基本信息
宁德刚  男  博导  中国科学院水生生物研究所
电子邮件: ningdegang@ihb.ac.cn
通信地址: 武汉市东湖南路7号
邮政编码: 420071

招生信息

   
招生专业
071007-遗传学
071005-微生物学
071010-生物化学与分子生物学
招生方向
微生物遗传学

教育背景

2000-09--2003-07 中国科学院水生生物研究所 博士

工作经历

   
工作简历
2014-05--今 中国科学院水生生物研究所 研究员
2003-08--2015-04 江苏大学 教授
社会兼职
2007-07--今 江苏省微生物学会理事
2006-07--今 中国微生物学会会员

专利与奖励

   
奖励信息
(1) 城市污水中致病性类弯曲菌生态特征及控制技术研究,三等奖,市地级,2009
(2) alr0117, a two-component histidine kinase gene, is,一等奖,其他级,2005
专利成果
[1] 宁德刚. FimH在制备基于枯草芽孢杆菌芽孢载体的鱼类靶向口服疫苗中的应用. ZL202010630949.5, 2021-09-14.

出版信息

   
发表论文
[1] Ning Degang. The Toxin-antitoxin Systems VapBC10 and VapBC12 with Physical Interaction between Their Components involved in Adaptation of Synechocystis sp. PCC 6803 to Cadmium Ion Stress. Toxin (Basel)[J]. 2021, [2] Sun, Rui, Zhang, Miao, Chen, Hui, Wei, Yao, Ning, Degang. Germination-Arrest Bacillus subtilis Spores as An Oral Delivery Vehicle of Grass Carp Reovirus (GCRV) Vp7 Antigen Augment Protective Immunity in Grass Carp (Ctenopharyngodon idella). GENES[J]. 2020, 11(11): http://dx.doi.org/10.3390/genes11111351.
[3] Fei, Qian, Gao, EBin, Liu, Biao, Wei, Yao, Ning, Degang. A Toxin-Antitoxin System VapBC15 from Synechocystis sp PCC 6803 Shows Distinct Regulatory Features. GENES[J]. 2018, 9(4): http://www.irgrid.ac.cn/handle/1471x/1760428.
[4] 宁德刚, 孙瑞. 细菌II型毒素-抗毒素系统活性的调控. 微生物学通报. 2016, 43(12): 2714-2719, http://lib.cqvip.com/Qikan/Article/Detail?id=670863437.
[5] Gao, EBin, Huang, Youhua, Ning, Degang. Metabolic Genes within Cyanophage Genomes: Implications for Diversity and Evolution. GENESnull. 2016, 7(10): https://doaj.org/article/559045fa07e348f1858d0cca7bba44dd.
[6] 宁德刚, 赵卫飞, 钱亚如. 蓝细菌Synechocystis PCC 6803染色体上的基因ssl2138和sll1092构成的毒素-抗毒素系统. 微生物学报[J]. 2013, 53(10): 1043-1049, [7] Ning, Degang, Jiang, Yan, Liu, Zhaoying, Xu, Qinggang. Characterization of a Chromosomal Type II Toxin-Antitoxin System mazEaFa in the Cyanobacterium Anabaena sp PCC 7120. PLOS ONE[J]. 2013, 8(2): https://doaj.org/article/f16fae484fb34d02b850cabae7ab473d.
[8] Ning, Degang, Liu, Shuibing, Xu, Weidong, Zhuang, Qiang, Wen, Chongwei, Tang, Xiaoxia. Transcriptional and Proteolytic Regulation of the Toxin-Antitoxin Locus vapBC10 (ssr2962/slr1767) on the Chromosome of Synechocystis sp PCC 6803. PLOS ONE[J]. 2013, 8(11): https://doaj.org/article/a4ea45c6759a40d38e706343e586e5cd.
[9] 宁德刚, 汤晓夏. 蓝藻Hox氢酶催化产氢的调控. 微生物学通报[J]. 2013, 40(11): 2083-2089, [10] Wen ChongWei, Ning DeGang, Liu RuiJiang, Zhang YeWang. A Novel Target for Starving Tumor Therapy: Endocrine-gland-derived Vascular Endothelial Growth Factor. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2012, 39(7): 622-630, https://www.webofscience.com/wos/woscc/full-record/WOS:000306678200004.
[11] Ning, Degang, Ye, Sen, Liu, Biao, Chang, Jianing. The Proteolytic Activation of the relNEs (ssr1114/slr0664) Toxin-Antitoxin System by Both Proteases Lons and ClpP2s/Xs of Synechocystis sp PCC 6803. CURRENT MICROBIOLOGY[J]. 2011, 63(5): 496-502, https://www.webofscience.com/wos/woscc/full-record/WOS:000295164200015.
[12] 宁德刚. Analysis of the expression and the activity of the putative alkaline phosphatases in cyanobacterium Anabaena FACHB 709. 2011, [13] Li, Guohui, Tang, Qi, Chen, Huiqing, Yao, Qin, Ning, Degang, Chen, Keping. Display of Bombyx mori Nucleopolyhedrovirus GP64 on the Bacillus subtilis Spore Coat. CURRENT MICROBIOLOGY[J]. 2011, 62(5): 1368-1373, https://www.webofscience.com/wos/woscc/full-record/WOS:000289110000004.
[14] Ning, Degang, Qian, Yaru, Miao, Xiaogang, Wen, Chongwei. Role of the all1549 (ana-rsh) Gene, A relA/spoT Homolog, of the Cyanobacterium Anabaena sp PCC7120. CURRENT MICROBIOLOGY[J]. 2011, 62(6): 1767-1773, https://www.webofscience.com/wos/woscc/full-record/WOS:000292561100017.
[15] Ning, D, Leng, X, Li, Q, Xu, W. Surface-displayed VP28 on Bacillus subtilis spores induce protection against white spot syndrome virus in crayfish by oral administration. JOURNAL OF APPLIED MICROBIOLOGY[J]. 2011, 111(6): 1327-1336, https://www.webofscience.com/wos/woscc/full-record/WOS:000297848900004.
[16] 徐旭东, 张唯, 王煜, 宁德刚. 鱼腥藻pcc7120异形胞分化中的基因调控关系. 中国海洋湖沼学会藻类学分会第七届会员大会暨第十四次学术讨论会论文摘要集null. 2008, http://ir.ihb.ac.cn/handle/342005/14678.
[17] Ning, DG, Xu, XD. alr0117, a two-component histidine kinase gene, is involved in heterocyst development in Anabaena sp PCC 7120. MICROBIOLOGY-SGM[J]. 2004, 150: 447-453, http://ir.ihb.ac.cn/handle/152342/9568.
[18] 宁德刚, 徐旭东. 鱼腥藻PCC7120基因组中一个影响异形胞发育和图式形成的新区域. 水生生物学报[J]. 2004, http://lib.cqvip.com/Qikan/Article/Detail?id=9017589.
[19] Ning De-gang, Xu Xu-Dong. A novel region involved in heterocyst development and pattern formation in the genome of Anabaena sp. PCC 7120. Acta Hydrobiologica Sinica[J]. 2004, 28(1): 40914-, http://www.irgrid.ac.cn/handle/1471x/543387.
[20] 徐旭东, 孔任秋, 刘珂, 王江新, 宁德刚. 集胞藻ORFs侧翼序列的PCR扩增和定向基因插入失活策略. 水生生物学报. 2001, 25(6): 544-, http://lib.cqvip.com/Qikan/Article/Detail?id=5767921.

科研活动

   
科研项目
(1) 集胞藻 PCC 6803毒素-抗毒素系统VapBC10在细胞适应镉胁迫中的调控作用,主持,国家级,2015-01--2018-12
(2) 异育银鲫抗CyHV-2口服重组芽胞免疫制剂的创制与应用示范,主持,省级,2015-01--2017-12
(3) 蓝藻毒素-抗毒素系统与细胞适应环境昼夜和季节变化关系的研究,主持,市地级,2014-05--2016-07
(4) 蓝藻适应环境胁迫的分子机制研究,主持,研究所(学校)级,2013-01--2015-12
(5) 枯草芽孢杆菌芽孢表面展示技术及应用,主持,国家级,2013-01--2016-12

指导学生

现指导学生

费倩  硕士研究生  071007-遗传学