基本信息
郭黎媛  女  硕导  中国科学院心理研究所
电子邮件: guoly@psych.ac.cn
通信地址: 北京市朝阳区林萃路16号院中国科学院心理研究所D401
邮政编码:

招生信息

   
招生专业
071010-生物化学与分子生物学
0710Z2-计算生物学
招生方向
精神神经疾病的发生发展规律
神经精神疾病生物标志物的鉴定

教育背景

2004-09--2009-06   北京大学   博士
1999-09--2004-06   山西医科大学   学士

工作经历

   
工作简历
2016-03~现在, 中国科学院心理研究所, 副研究员
2009-07~2016-02,中国科学院心理研究所, 助理研究员
2004-09~2009-06,北京大学, 博士
1999-09~2004-06,山西医科大学, 学士

专利与奖励

   
专利成果
( 1 ) 自身免疫类神经疾病的诊断, 2021, 第 2 作者, 专利号: CN112285363A

( 2 ) 一种人类大脑基因时空表达模式在线分析系统及其方法, 2019, 第 2 作者, 专利号: CN110428867A

( 3 ) 一种人类大脑基因表达时空常模的建立方法, 2019, 第 2 作者, 专利号: CN110349625A

出版信息

   
发表论文
(1) Preservation Analysis on Spatiotemporal Specific Co-expression Networks Suggests the Immunopathogenesis of Alzheimer's Disease, FRONTIERS IN AGING NEUROSCIENCE, 2021, 通讯作者
(2) Autoantibody against the Rab6A/Rab6B in primary autoimmune cerebellar ataxia associated with Sjogren's syndrome: A case report, JOURNAL OF NEUROIMMUNOLOGY, 2021, 第 1 作者
(3) Prevalence and Correlates of Anxiety and Depressive Symptoms in Patients With and Without Multi-Drug Resistant Pulmonary Tuberculosis in China, FRONTIERS IN PSYCHIATRY, 2021, 通讯作者
(4) A Systematic Analysis Revealed the Potential Gene Regulatory Processes of ATRA-Triggered Neuroblastoma Differentiation and Identified a Novel RA Response Sequence in the NTRK2 Gene, BIOMED RESEARCH INTERNATIONAL, 2020, 第 1 作者
(5) Identification of a missense ARSA mutation in metachromatic leukodystrophy and its potential pathogenic mechanism, MOLECULAR GENETICS & GENOMIC MEDICINE, 2020, 第 1 作者
(6) Identification of key genes and pathways for Alzheimer’s disease via combined analysis of genome-wide expression profiling in the hippocampus, BIOPHYSICS REPORTS, 2019, 第 5 作者
(7) BEST: a web server for brain expression Spatio-temporal pattern analysis, BMC BIOINFORMATICS, 2019, 第 1 作者
(8) Identification of key genes and pathways for Alzheimer's disease via combined analysis of genome-wide expression profiling in the hippocampus, Identification of key genes and pathways for Alzheimer’s disease via combined analysis of genome-wide expression profiling in the hippocampus, 生物物理学报:英文版, 2019, 第 5 作者
(9) RSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks, NUCLEIC ACIDS RESEARCH, 2018, 第 1 作者
(10) Common variants near IKZF1 are associated with primary Sjogren's syndrome in Han Chinese, PLOS ONE, 2017, 第 4 作者
(11) A combined analysis of genome-wide expression profiling of bipolar disorder in human prefrontal cortex, JOURNAL OF PSYCHIATRIC RESEARCH, 2016, 第 4 作者
(12) rVarBase: an updated database for regulatory features of human variants, NUCLEIC ACIDS RESEARCH, 2016, 第 1 作者
(13) I-GSEA4GWAS v2: a web server for functional analysis of SNPs in trait-associated pathways identified from genome-wide association study, PROTEIN & CELL, 2015, 第 3 作者
(14) Network analysis reveals a stress-affected common gene module among seven stress-related diseases/systems which provides potential targets for mechanism research, SCIENTIFIC REPORTS, 2015, 第 1 作者
(15) Applying Differentially Expressed Genes From Rodent Models of Chronic Stress to Research of Stress-Related Disease: An Online Database, PSYCHOSOMATIC MEDICINE, 2014, 第 1 作者
(16) Applying differentially expressed genes from rodent models of chronic stress to researches of stress-related disease: an online database, Psychosomatic Medicine., 2014, 第 1 作者
(17) rSNPBase: a database for curated regulatory SNPs, NUCLEIC ACIDS RESEARCH, 2014, 第 1 作者
(18) The neural correlates of reward-related processing in major depressive disorder: A meta-analysis of functional magnetic resonance imaging studies, JOURNAL OF AFFECTIVE DISORDERS, 2013, 第 3 作者
(19) MK4MDD: A Multi-Level Knowledge Base and Analysis Platform for Major Depressive Disorder, PLOS ONE, 2012, 第 1 作者
(20) ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework, NUCLEIC ACIDS RESEARCH, 2011, 第 4 作者
(21) Mechanisms involved in phosphatidylinositol 3-kinase pathway mediated up-regulation of the mu opioid receptor in lymphocytes, BIOCHEMICAL PHARMACOLOGY, 2010, 第 3 作者
(22) The mechanism involved in the repression of the mu opioid receptor gene expression in CEM x 174 cells infected by simian immunodeficiency virus, JOURNAL OF LEUKOCYTE BIOLOGY, 2009, 第 3 作者
(23) Involvement of STAT5a signaling in morphine-induced up-regulation of the cyclin D1, BIOCHEMICAL PHARMACOLOGY, 2009, 第 1 作者

科研活动

   
科研项目
( 1 ) 慢性温和应激环境下BALB/c小鼠全脑基因表达调控网络构建与分析, 负责人, 国家任务, 2013-01--2015-12
( 2 ) 人脑视知觉认知数据计算与组织, 参与, 国家任务, 2015-01--2019-08