General

吴丽 女   化学与化工学院
Email:  wuli@ucas.ac.cn
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Research Areas

Regulation of Functional Nucleic Acid 

Research on chirality-related life evolution 

Biomacromolecule


Education

Tianjin University

Experience

2017-present  Associate Professor, School of Chemistry, University of Chinese Academy of Sciences

2014-2016  Lecturer, School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences

2011-2014  Postdoctoral fellow, Peking University School of Medicine

2007-2009  Postdoctoral fellow, Institute of Advanced Biotechnology (FIBER), Konan University, Japan


Publications

   (1) 手性氨基酸对DNA链式聚合反应的影响, Effect of chiral amino acids on DNA chain polymerization, 中国科学院大学学报, 2021, 通讯作者
(2) Redox manipulation of enzyme activity through physiologically active molecule, ISCIENCE, 2021, 通讯作者
(3) Comparative study on the removal of different-type organic pollutants on three-dimensional hexagonal-tungsten trioxide/reduced graphene oxide nanorod arrays: adsorption and visible light photodegradation, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS, 2021, 通讯作者
(4) 有机合成协同思政教育的课程体系构建探索, Exploration of Course Ideology and Politics Merging into Education of Organic Synthesis, 大学化学, 2021, 通讯作者
(5) Facile synthesis of nitrogen-vacancy pothole-rich few-layer g-C3N4 for photocatalytic nitrogen fixation into nitrate and ammonia, JOURNAL OF ALLOYS AND COMPOUNDS, 2021, 通讯作者
(6) A ratiometric nanoprobe based on carboxylated graphitic carbon nitride nanosheets and Eu3+ for the detection of tetracyclines, ANALYST, 2021, 通讯作者
(7) New insight into enzymatic hydrolysis of peptides with site-specific amino acid d-isomerization, BIOORGANIC CHEMISTRY, 2020, 通讯作者
(8) Replication of DNA Containing Mirror-Image Thymidine in E. coli Cells, CHEMICAL RESEARCH IN TOXICOLOGY, 2020, 通讯作者
(9) 偶氮苯修饰的发夹DNA对RNA转录的光调控, Photoregulating RNA transcription using azobenzene modified hairpin DNA, 中国科学院大学学报, 2020, 通讯作者
(10) Compatibility and Fidelity of Mirror-Image Thymidine in Transcription Events by T7 RNA Polymerase, MOLECULAR THERAPY-NUCLEIC ACIDS, 2020, 通讯作者
(11) Mutation analysis of L-thymidine-induced replication products using restriction enzyme mediated assay, Current Protocol in Nucleic Acid Chemistry, 2020, 通讯作者
(12) Fe3O4 nanoparticles functionalized with poly(ethylene glycol) for the selective separation and enrichment of Au(iii), NEW JOURNAL OF CHEMISTRY, 2020, 通讯作者
(13) Bioactivatable reductive cleavage of azobenzene for controlling functional dumbbell oligodeoxynucleotides, BIOORGANIC CHEMISTRY, 2019, 通讯作者
(14) 生物体系中还原裂解氮氮双键的研究进展, Research progress on reduction cleavage of azo bonds in biological systems, 中国科学:化学, 2019, 第 6 作者
(15) Reversible Photocontrol of Thrombin Activity by Replacing Loops of Thrombin Binding Aptamer using Azobenzene Derivatives, BIOCONJUGATE CHEMISTRY, 2019, 通讯作者
(16) Colorimetric detection of iron (II) using 4-mercaptobenzoic acid and 3,3′,5,5′-tetramethylbenzidine modified silver nanoparticles, MICROCHEMICAL JOURNAL, 2019, 通讯作者
(17) Influence of d -Amino Acids in Beer on Formation of Uric Acid, Food Technology and Biotechnology, 2019, 通讯作者
(18) A rapid pretreatment of PVC products for high-throughput and visual detection of trace heavy metals, MONATSHEFTE FUR CHEMIE, 2019, 通讯作者
(19) 偶氮苯修饰的DNA对引物延伸的光调控, Photoregulating primer extension using azobenzene linked DNA template, 中国科学院大学学报, 2019, 通讯作者
(20) 偶氮苯作用的核酸开关在生物体内的可逆光调控, Reversible photoregulation in biological systems via introduction of azobenzene into nucleic acid, 中国科学:化学, 2018, 第 10 作者
(21) Graphene and AuNPs based electrochemical aptasensor for ultrasensitive detection of hydroxylated polychlorinated biphenyl, ANALYTICA CHIMICA ACTA, 2018, 通讯作者
(22) D-氨基酸诱导的酿酒酵母细胞内活性氧的累积, Reactive oxygen species accumulation induced by D-amino acid in Saccharomyces cerevisiae, 中国科学院大学学报, 2018, 第 3 作者
(23) Caged circular siRNAs for photomodulation of gene expression in cells and mice, CHEMICAL SCIENCE, 2018, 第 6 作者
(24) Colorimetric and visual determination of Au(III) ions using PEGylated gold nanoparticles, MICROCHIMICA ACTA, 2018, 通讯作者
(25) Enantioselectivity of D-amino acid oxidase in the presence of ionic liquids, RSC ADVANCES, 2017, 通讯作者
(26) Mirror-image thymidine discriminates against incorporation of dNTP into DNA and repairs itself by DNA polymerases, Bioconjugate Chemistry, 2017, 通讯作者
(27) PH-Dependent Enantioselectivity of D-amino Acid Oxidase in Aqueous Solution, SCIENTIFIC REPORTS, 2017, 通讯作者
(28) Acid generation by 1,4-bis(phenylsulfonyloxy)benzene and their photochemical mechanism, MONATSHEFTE FUR CHEMIE, 2017, 通讯作者
(29) Colorimetric aggregation assay for arsenic(III) using gold nanoparticles, MICROCHIMICA ACTA, 2017, 通讯作者
(30) Facile method for the synthesis of Fe3O4@ HCP core-shell porous magnetic microspheres for fast separation of organic dyes from aqueous solution, RSC ADVANCES, 2016, 第 6 作者
(31) Photoregulating rna digestion using azobenzene linked dumbbell antisense oligodeoxynucleotides, BIOCONJUGATE CHEMISTRY, 2015, 第 1 作者
(32) Photoswitching properties of hairpin ODNs with azobenzene derivatives at the loop position, MEDCHEMCOMM, 2015, 第 1 作者
(33) Synthesis of Site-Specifically Phosphate-Caged siRNAs and Evaluation of Their RNAi Activity and Stability, CHEMISTRY-A EUROPEAN JOURNAL, 2014, 第 1 作者
(34) Caged circular antisense oligonucleotides for photomodulation of RNA digestion and gene expression in cells, NUCLEIC ACIDS RESEARCH, 2013, 第 1 作者
(35) Manipulation of gene expression in zebrafish using caged circular morpholino oligomers, NUCLEIC ACIDS RESEARCH, 2012, 第 2 作者
(36) Reversible stability switching of a hairpin DNA via a molecularly designed photo-responsive linker unit, Chemical Communications, 2009, 第 1 作者
(37) Photochemical Regulation of Gene Expression Using Caged siRNAs with Single Terminal Vitamin E Modification, Angewandte Chemie, 


Students