Microbial communities in deep-sea environments

Microbiol genomics and evolution

Molecular evolution of microbial genomes

09/1993-06/1997        Lanzhou University, B.S. in Biochemistry, Dept. of Biology, China

09/1997-06/2000        Zhejiang University, M. S. in Marine Biotechnology, China

01/2001-12/2003       The University of Hong Kong, Ph.D. in Molecular Evolution and Bioinformatics

05/2004-12/2007        Postdoctoral Fellow, Genome Research Centre and Department of Zoology, The University of Hong Kong

01/2008-10/2008        Senior Research Assistant, Department of Microbiology, University of Hong Kong

02/2009-02/2012        Postdoctoral Fellow, King Abdullah University of Science and Technology, Saudi Arabia

03/2012-08/2013        Postdoctoral Fellow, Division of Life Science, Hong Kong University of Science and Technology, Hong Kong

08/2013-present          Senior Scientist, Institute of Deep Sea Science and Engineering, Chinese Academy of Sciences, Sanya, China

Genomics, 2016

The second prize of National Natural Science Award (rank 3)

Excellence prize of 'one hundred talents' program of CAS

1. Wang Y, Liu BQ, Luo QJ, Fei ZQ, Pei LQ, and Xue QZ. 2000. RAPD analysis of genetic variation among Porphyra haitanensis strains. Periodical of Ocean University of China. 30: 225-229. (In Chinese)

2. Luo BQ, Pei LQ, Pan SY, Wang Y, and Fei ZQ. 2002. Utilization of inorganic carbon in free-living conchocelis of Porphyra haitanensis. Journal of Fisheries of China 26: 477-480. (In Chinese)

3. Wang Y, Pei LQ, Luo Q J, Liu BQ, Fei ZQ, and Xue QZ. 2002. DNA extraction from Porphyra conchocelis. ACTA Oceanologica Sinica 24:146-148. (In Chinese)

4. Xia X, Xie Z, Salemi M, Chen L and Wang Y. 2003. An index of substitution saturation and its application. Molecular phylogenetics and evolution 26: 1-7.

5. Zeng FY, Chan CW, Chan MN, Chen JD, Chow KY, Hon CC, Hui KH, Li J, Li VY, Wang CY, Wang PY, Guan Y, Zheng B, Poon LL, Chan KH, Yuen KY, Peiris JS and Leung FC. 2003. The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849 (HK-39). Exp Biol Med (Maywood) 228:866-873.

6. Wang Y and Leung FCC. 2004. An evaluation of new criteria for CpG islands in the human genome as gene markers. Bioinformatics 20:1170-1177.

7. Wang Y, Rocha EPC, Leung FCC, and Danchin A. 2004. Cytosine methylation is not the major factor inducing CpG dinucleotide deficiency in bacterial genomes. Journal of Molecular Evolution 58:692-71

8. Wang Y, and Leung FCC. 2004. DNA structure constraint is probably a fundamental factor inducing CpG deficiency in bacteria. Bioinformatics 22:3336-3345.

9. Wang Y, and Leung FCC. 2006. Long inverted repeats in eukaryotic genomes: Recombinogenic motifs determine genomic plasticity. FEBS Letters 580: 1277-1284.

10. Wang Y, Wang ZG, Li J, Wang YJ and Leung FCC. 2007. Database for chicken full-length cDNAs. Physiological Genomics 28: 141-145.

11. Wang Y, Fong PY, Leung FCC, Mak W, and Sham PC. 2007 Increased gene coverage and Alu frequency in large linkage disequilibrium blocks of the human genome. Genetics and Molecular Research 6: 1131-1141.

12. Wang Y, Zeng F, Hon CC, Zhang YZ, and Leung FCC. 2008. The mitochondrial genome of Pleurotus ostreatus (oyster mushroom). FEMS Microbiology Letters 280: 34-41.

13. Wang Y and Leung FCC. 2008. GC content increased at CpG flanking positions of fish genes compared with sea squirt orthologs as a mechanism for reducing impact of DNA methylation. PLoS ONE 3: e3612

14. Wang Y, and Leung FCC. 2008. Loss of CpG sites in GC-poor regions of vertebrate genomes: An indication of context-dependent mutagenicity of methylated CpG sites. Genomics, Proteomics & Bioinformatics 3-4: 144-154

15. Wang Y, and Leung FCC. 2009. A study on genomic distribution and sequence features of human long inverted repeats reveals species-specific intronic stem-loops. FEBS Journal 276: 1986-1998

16. Wang, Y. and F. C. C. Leung. 2009. Acquisition of inverted GSTM exons by an intron of primate GSTM5 gene. Journal of Human Genetics 54: 271-276

17. Wang, Y. and Leung FCC. 2009. In silico prediction of two classes of honeybee genes with CpG deficiency or CpG enrichment and sorting according to gene ontology classes. Journal of Molecular Evolution 68: 700-705

18. Wang Y, and Leung FCC. 2009. Comparative genomic study on context-dependence of CpG mutations: Acceleration effect of 5’ T nucleotides and new evidence of strand asymmetry in genes. Online Journal of Bioinformatics 10: 165-179

19. Wang Y, and Leung FCC. 2009. Discovery of a long inverted repeat in human POTE genes. Genomics 94: 278-283

20. Wang Y, and Qian PY. 2009. Conservative fragments in bacterial 16S rRNA genes and primer design for 16S ribosomal DNA amplicons in metagenomic studies. PLoS ONE 4: e7401.

21. Zhang HM, Zhao CQ, Li X, Zhu Y, Gan CS, Wang Y, Ravasi T, Qian PY, Wong SC, Sze SK, 2010. Study of monocyte membrane proteome perturbation during lipopolysaccharide-induced tolerance using iTRAQ-based quantitative proteomic approach. Proteomics 10: 2780-2789

22. Qian PY*, Wang Y, Lee OO, Yang JK, Lau SCK, Abdulaziz S and Wong T. 2011. Vertical stratification of microbial communities in the Red Sea. ISME J. 5: 507-518.

23. Lee OO, Wang Y, Yang JK, Al-Suwailem A, Qian PY*. 2011. Pyrosequencing reveals highly diverse and species-specific microbial communities in sponges from the Red Sea. ISME J. 5: 650-664.

24. Wang Y, Yang JK, Lee OO, Dash S, Lau SCK, Al-Suwailem A, Wong TYH, Qian PY*. 2011. Hydrothermally generated aromatic compounds are consumed by bacteria colonizing in Atlantis II Deep of the Red Sea. ISME J. 5: 1652-1659.

25. Wang Y, Yang JK, Lee OO, Lau SCK, Wong TYH, Al-Suwailem A, Danchin A, Qian PY*. 2011 Bacterial niche-specific genome expansion is coupled with highly frequent gene disruptions in deep-sea sediments. PLoS ONE e29149.

26. Lee OO, Yang JK, Bougouffa S, Wang Y, Batang Z, Tian RM, Al-Suwailem A, and Qian PY*，2012. Spatial and Species Variations in Bacterial Communities Associated with Corals from the Red Sea as Revealed by Pyrosequencing. Appl. Environ. Microbiol. 78: 7173-7184.

27. Arellano SM, Lee OO, Lafi FF, Yang JK, Wang Y, Young CM, Qian PY*, 2013. Deep sequencing of Myxilla (Ectyomyxilla) methanophila, an epibiotic sponge on cold-seep tubeworms, reveals methylotrophic, thiotrophic, and putative hydrocarbon-degrading microbial associations. Microb Eco. 64: 450-461.

28. Wang Y, Cao HL, Zhang GS, Bougouffa S, Lee OO, Al-Suwailem A, Qian PY*, 2013. Autotrophic microbe metagenomes and metabolic pathways differentiate adjacent red sea brine pools. Sci. Rep. 3: 17481 

29. Wang Y, Lee OO, Yang JK, Li T G, Qian PY*. 2013. Artifactual pyrosequencing reads in multiple-displacement-amplified sediment metagenomes from the Red Sea. PeerJ 1: e69 

30. Bougouffa S, Yang JK, Lee OO, Wang Y , Batang Z, Al-Suwailem A, Qian PY*. 2013. Distinctive microbial community structure in highly stratified deep-sea brine water columns. Appl. Env. Microbiol. 79: 3425-3437 

31. Zhang WP, Wang Y, Lee OO, Tian RM, Cao HL,  Gao ZM, Li YX, Yu L, Xu Y, Qian PY*. 2013. Adaptation of intertidal biofilm communities is driven by metal ion and oxidative stresses. Sci Rep. 3: 3180 (共同第一作者) 

32. Lee OO, Chung HC, Yang J, Wang Y, Wang H, Qian PY*. 2014. Molecular techniques revealed highly diverse microbial communities in natural marine biofilms on polystyrene dishes for invertebrate larval settlement. Microb Eco. 68: 81-93.

33. Lee OO, Wang Y, Tian RM, Zhang WP,    Shek CS,        Bougouffa S, Al-Suwailem A, Batang ZB, Xu W, Wang GC, Zhang XX,        Lafi FF, Bajic VB, Qian PY*, 2014. In situ environment rather than substrate type dictates microbial community structure of biofilms in a cold seep system. Sci Rep. 4: 3587 (共同第一作者)

34. Wang Y, Zhang WP, Cao HL, Shek CS, Tian RM, Wong YH, Batang Z, Al-Suwailem A, Qian PY*. 2014. Diversity and distribution of eukaryotic microbes in and around a brine pool adjacent to the Thuwal cold seeps in the Red Sea. Front Microbiol. 5:37

35. Cao HL, Wang Y, Lee OO, Zeng X, Shao ZZ, Qian PY*. 2014. Microbial Sulfur Cycle in Two Hydrothermal Chimneys on the Southwest Indian Ridge. mBio 5(1):e00980-13.

36. Wang Y, Tian RM, Gao ZM, Bougouffa S, He LS, and Qian PY*. 2014. Optimal eukaryotic 18S and universal 16S/18S ribosomal RNA primers and their application in a study of symbiosis. PLoS ONE 9: e90053.

37. Gao ZM, Wang Y, Tian RM, Wong YH, Batang ZB, Al-Suwailem AM, Bajice VB, Qian PY*. 2014. Symbiotic adaptation drives genome streamlining of the cyanobacterial sponge symbiont candidatus Synechococcus spongiarum. mBio. 5(2): e00079.

38. Tian RM, Wang Y, Bougouffa S, Gao ZM, Cai L, Bajic V, Qian PY*. 2014. Genomic analysis reveals versatile heterotrophic capacity of a potentially symbiotic sulfur-oxidizing bacterium in sponge. Environ. Microbiol. 16: 3548-3561. (共同第一作者).

39. Zhang P, Wang Y, Tian RM, Bougouffa S, Yang B, Cao HL, Zhang G, Wong YH, Xu W, Batang Z, Alsuwailem A, Zhang XX, Qian PY*. 2014. Species sorting during biofilm assembly by artificial substrates deployed in a cold seep system. Sci. Rep. 4:6647.

40. Zhang WP, Bougouffa S, Wang Y, Lee OO, Yang JK, Chan C, Song XY, Qian PY*. 2014. Toward Understanding the Dynamics of Microbial Communities in an Estuarine System. PLOS ONE. 9: e94449.

41. Tian RM, Wang Y, Bougouffa S, Gao ZM, Cai L, Zhang WP, Bajic V, Qian PY*. 2014. Effect of Copper Treatment on the Composition and Function of the Bacterial Community in the Sponge Haliclona cymaeformis. mBio. 5: e01980.

42. Gao ZM, Wang Y, Lee OO, Tian RM, Wong YH, Bougouffa S, Batang Z, Al-Suwailem A, Lafi FF, Bajic VB, Qian PY*. 2014. Pyrosequencing reveals the microbial communities in the Red Sea sponge Carteriospongia foliascens and their impressive shifts in abnormal tissues. Microb. Eco, 68: 621-32.

43. Tian RM, Lee OO, Wang Y, Cai L, Bougouffa S, Chiu JMY, Wu RSS , Qian PY*, 2015. Effect of polybrominated diphenyl ether (PBDE) treatment on the composition and function of the bacterial community in the sponge Haliclona cymaeformis. Front Microbiol 5: 799.

44.Yang B, Zhang W, Tian R, Wang Y, Qian PY*. 2015. Changing composition of microbial communities indicates seepage fluid difference of the Thuwal Seeps in the Red Sea. Antonie Van Leeuwenhoek, 108(2):461-471.

45. Gao ZM, Wang Y, Tian RM, Lee OO, Wong TH,  Batang ZB,  Al-Suwailem A, Lafi FF, Bajic VB, Qian PY*. 2015. Pyrosequencing revealed shifts of prokaryotic communities between healthy and disease-like tissues of the Red Sea sponge Crella cyathophora. PeerJ, 3: e890.

46. Cao H, Zhang W, Wang Y, Qian PY. 2015*. Microbial community changes along the active seepage site of one cold seep in the Red Sea. Front Microbiol. 6:739.

47.Zhang WP, Wang Y, Bougouffa S, Tian RM, Cao HL, Li YX, Cai L, Wong YH, Zhang G, Zhou GW, Zhang XX, Bajic VB, Al-suwailem A, Qian PY*. 2015. Synchronized dynamics of bacterial niche-specific functions during biofilm development in a cold seep brine pool. Environmental Microbiology, 17(10): 4089-4104.

48. Wang Y, Li JT, He LS, Yang B, Gao ZM, Cao HL, Batang Z, Al-Suwailem A, Qian PY*. 2015. Zonation of Microbial Communities by a Hydrothermal Mound in the Atlantis II Deep (the Red Sea). Plos ONE, 10(10): e0140766.

49. Wang Y, Gao ZM, Xu Y, Li GY, He LS, Qian PY*. 2016. An evaluation of multiple annealing and looping based genome amplification using a synthetic bacterial community. ACTA Oceanol Sin, 35: 131-136.

50. Wang Y, Huang JM, Wang SL, Gao ZM, Zhang AQ, Danchin A*, He LS*. 2016. Genomic characterization of symbiotic mycoplasmas from the stomach of deep-sea isopod bathynomus sp. Environmental Microbiology, 18(8): 13411.

51. Wang Y, Gao ZM, Li JT, Bougouffa S, Tian RM, Bajic VB, Qian PY*. 2016. Draft genome of a bacterium in the phylum Aerophobetes (CD12) reveals a facultative lifestyle in deep-sea anaerobic sediments. Science Bulletin, 61: 1176-1186.

52. Wang Y*, Li TG, Wang MY, Lai QL, Li JT, Gao ZM, Shao ZZ, Qian PY*. 2016. Archive of bacterial community in anhydrite crystals from a deep-sea basin provides evidence of past oil-spilling in a benthic environment in the Red Sea. Biogeoscience, 13, 6405-6417.

53. Yang B , Wang Y, Qian PY*. 2016. Sensitivity and correlation of hypervariable regions in 16S rRNA genes in phylogenetic analysis. BMC Bioinformatics, 17: 135.

54. Wang Y*. Huang JM. 2017. LIR: A package for identification of long inverted repeats in genomes. Genomics, Proteomics & Bioinformatics, 15: 141-146.

55. Speth DR, Lagkouvardos I, Wang Y, Qian PY, Dutilh BE, Jetten MSM. 2017. Draft genome of Scalindua rubra, obtained from the interface above the Discovery Deep brine in the Red Sea, sheds light on potential salt adaptation strategies in anammox bacteria. Microbial Ecology, 74: 1-5.

56. Li JT, Cui JM, Yang QH, Cui GJ, Wei BB, Wu ZJ,WangY, Zhou HY *. 2017. Oxidative weathering and microbial diversity of an inactive seafloor hydrothermal sulfide chimney. Front Microbiol, 8:1378

57. Lin HN, Wang Y, Huang JM, Lai QL, Xu Y. 2017 Deinococcus planoceraesp. nov., isolated from a marine flatworm. Antonie van Leeuwenhoek, 110: 811-817.

58. Gao Z-M, Zhou G-W, Huang H, Wang Y *. 2017. The Cyanobacteria-dominated spongeDactylospongia elegansin the South China Sea: Prokaryotic community and metagenomic insights. Front Microbiol, 8: 1387.

59. Kou Q., Chen J., Li* XZ, He LS, Wang Y.. 2017. New species of the giant deep-sea isopod genus Bathynomus (Crustacea, Isopoda, Cirolanidae) from Hainan Island, South China Sea. Intergrative Zool. 12: 283-291.

60. Yan GY, Zhang G, Huang JM, Lan Y, Sun J, Zeng C, Wang Y, Qian PY, He LS. 2017. Comparative transcriptomic analysis reveals candidate genes and pathways involved in larval settlement of the barnacle megabalanus volcano. Int J Mol Sci. 18: 2253.

61. Kou Q, Li X.Z.*, He L-S, Wang Y.2018. Rediscovery of the hadal species Amblyops magnus Birstein & Tchindonova, 1958 (Crustacea: Mysida: Mysidae): first record from the Mariana Trench. Zootaxa 4402:42-52

62. He L-S, Zhang G, Wang Y, Yan G-Y, Qian P-Y*. 2018 Toward understanding barnacle cementing by characterization of one cement protein-100kDa in Amphibalanus amphitrite. Biochemical and Biophysical Research Communications (BBRC). 495: 969-975.

63. He L-S, Zhang P-W, Huang J-M, Zhu F-C, Danchin A., Wang Y.*2018 The enigmatic genome of an obligate ancient Spiroplasma symbiont in a hadal holothurian. Appl Env Microbiol. 84: e01965-17

64.Wang Y*, Zhu FC, He LS, Danchin A.*. 2018. Unique tRNA gene profile suggests paucity of nucleotide modifications in anticodons of a deep-sea symbiotic Spiroplasma. Nucleic Acids Res. 46：2197-2203. 

65. Wu YZ, Qiu JW, Qian PY*, Wang Y * 2018. The vertical distribution of prokaryotes in the surface sediment of Jiaolong cold seep at the northern South China Sea. Extremophiles, 22：499-510.

66. Wang S-L, Li Y-L, Han Z, Chen X., Chen Q-J, Wang Y, He L-S* 2018. Molecular characterization of a novel N-acetylneuraminate lyase from a deep-sea symbiotic Mycoplasma. Mar. Drugs 16: 80

67.Wang Y*, Huang JM. 2018. Assessment of molecular for classification of bacterial phyla using topological dissimilarity of phylogenetic trees. J Phylo Evol Biol, 6: 100204

68. Li W-L, Huang J-M, Zhang P-W, Cui G-J, Wei Z-F, Wu Y-Z, Gao Z-M, Han Z., Wang Y.* 2019. Periodic and spatial spreading of alkanes and Alcanivorax bacteria in deep waters of the Mariana Trench. Appl. Env. Microbiol. 85: e02089-18 

69. Wang Y*, Huang J-M, Cui G-J, Nunoura T, Takaki Y. Li W-L, Li J, Gao Z-M, Ken T, Zhang A-Q, Stepanauskas R. 2019.       Genomics insights into ecotype formation of ammonia-oxidizing archaea in the deep ocean. Environ. Microbiol. 21:716-729.

70. Wang Y*, Gao Z-M, Li J, He L-S, Cui G-J, Li W-L, Chen J, Xin Y-Z, Cai D-S, Zhang A-Q. 2019. Hadal water sampling by in situ microbial filtration and fixation (ISMIFF) apparatus. Deep-Sea Res I. 144:132-137

71. Kou Q. Meland K; Li XZ*, He LS, Wang Y. 2019. Deepest record of Eucopia sculpticauda (Crustacea: Lophogastrida: Eucopiidae) and the order, with new insights into the distribution and genetic diversity of the species. 2019. Bull Mar Sci. bms.2018.0074.

72. Cui G-J. Li J. Gao Z-M, Wang Y*.2019. Spatial variations of microbial communities in abyssal and hadal sediments across the Challenger Deep. PeerJ 7:e6961.

73. Huang JM, Baker JB, Li JT, Wang Y.* 2019. New microbial lineages capable of carbon fixation and nutrient cycling in deep-sea sediments of the northern South China Sea. Appl. Env. Microbiol. 85: 00523-19

74. Huang JM, Wang Y.* 2019. Genomic differences within the phylum Marinimicrobia: From waters to sediments in the Mariana Trench. Marine Genomics. 100699

75. Cheng XY, Wang Y, Li JY, Yan GY, He LS*. 2019. Comparative analysis of the gut microbial communities between two dominant amphipods from the Challenger Deep, Mariana Trench. Deep-Sea Res I. 103081

76. Gao, Z.M., Huang, J.M., Cui, G.J., Li, W.L., Li, J., Wei, Z.F., Chen, J., Xin YZ, Cai, D.S., Zhang, A.Q., Wang, Y.*, 2019. In situ meta-omic insights into the community compositions and ecological roles of hadal microbes in the Mariana Trench. Environmental Microbiology. 21:4192-4108

77. Kou, Q., Meland, K., Li, X.Z.*, He, L.S., Wang, Y., 2019. "Unicorn from Hades", a new genus of Mysidae (Malacostraca: Mysida) from the Mariana Trench, with a systematic analysis of the deep-sea mysids. Mol Phylogenet Evol 143:106666

78. Lian, C.-A., Yan, G.Y., Huang, J.M., Danchin, A., Wang, Y.*, He, L.S.*, 2020. Genomic characterization of a novel gut symbiont from the hadal snailfish. Front. Microbiol. 10:2978.

79. Wei, Z.F., Li, W.L., Li, J., Chen, J., Xin, Y. Z., He, L. S., Wang, Y.*, 2020. Multiple in situ nucleic acid collections (MISNAC) from deep-sea waters. Front. Mar. Sci. 18: 00081.

80. Wang, Y.*, Huang, J.M., Zhou, Y.L. Almerda, A., Finn, R.D., Danchin, A., He, L.S., 2020. Phylogenomics of expanding uncultured environmental Tenericutes provides insights into their pathogenicity and evolutionary relationship with Bacilli. BMC Genomics 21: 408.

81. Wei, Z.F., Li, W.L., Huang, J.M., Wang, Y.*, 2020. Metagenomic studies of SAR202 bacteria at the full-ocean depth in the Mariana Trench. Deep Sea Res I 165:103396.

82. Li, W.L., Wu, Y.Z., Zhou, G.W., Huang, H., Wang, Y.*, 2020. Metabolic diversification of anaerobic methanotrophic archaea in a deep‑sea cold seep. Mar. Life Sci. Technol. 2: 431-441

83. Cui, G.J., Zhou, Y.L., Li,W.L., Gao,Z.M.,Huang,J.M., Wang, Y.*, 2020. A novel bacterial phylum that participates in carbon and osmolytecycling in the Challenger Deep sediments. Environ. Microbiol. 23: 3758-3772

84. Lu, R., Gao, Z.M.*, Li, W.L., Wei, Z.F., Wei, T.S., Huang, J.M., Li, M., Tao, J., Wang, H.B., Wang, Y.*, 2021. Asgard archaea in the Haima cold seep: spatial distribution and genomic insights. Deep Sea Res I. 170: 103489

85. Li, Z. X., Pan, D., Wei, G., Pi, W., Zhang, C., Wang, J.H., Peng, Y.Y., Zhang, L., Wang, Y., Hubert, C.R.J., Dong, X.Y.*, 2021. Deep sea sediments associated with cold seeps are a subsurface reservoir of viral diversity. ISME J. 15：2366–2378

86. Li, Q-M, Zhou, Y.L., Wei, Z.-F., Wang, Y.*, 2021. Phylogenomic insights into distribution and adaptation of Bdellovibrionota in marine waters. Microorganisms. 9: 757.

87. Wang, Y.*, Li, W.L., Li, Q.M., Zhou, Y.L., Gao, Z.M., Feng, D., 2021. Deep-sea carbonates are a reservoir of fossil microbes previously inhabiting cold seeps. Front. Mar. Sci. 8: 698545. 

88. Dong, X.Y., Zhang, C.W., Li, W.L., Weng, S.Z., Song, W.Z., Li, J.T., Wang, Y.*, 2021. Functional diversity of microbial communities in inactive seafloor sulfide deposits. FEMS Microbiology Ecology, 97: fiab108.

89. Li, W.-L., Dong, X.Y., Lu, R. Zheng, P.F., Feng, D.,Wang, Y.* 2021. Diverse microbial populations potentially mediate sulfur cycling in sediments associated with cold seeps. Environ. Microbiol. 28: 6844-6858. 

90. Yong Wang*, Jun Li, Zhanfei Wei, Qingmei Li, Yingli Zhou, Wenli Li, Jun Chen, Suixue Wang, Yongzhi Xin, Aiqun Zhang. 2021. In situ cultivation of deep-sea water with bicarbonate fueled a different microbial community. Acta Oceanologica Sinica，in press.

Microbial composition in deep-sea environments and extreme conditions;

Molecular evolution of microbial species;

Genomic characteristics of extremophiles

Pei LQ, Wang Y and Xue QZ. 2000 RAPD analysis of genetic variation in seaweed Porphyra haitanensis. Proceedings of the International Symposium on Marine Biotechnology. 6-8 December, Qingdao, China, 95.

Lee OO, Yang J, Wang Y, Batang Z, Al-Suwailem A, Qian PY. 2011, Pyrosequencing reveals spatial and species variations in bacterial communities associated with corals from the Red Sea. The 4th Congress of European Microbiologists, Geneva, Switzerland

Wang Y, Gao ZM, Xu Y, He LS, Qian PY. 2014. An Evaluation of Multiple Annealing and Looping Based Amplification (MALBAC) Using a Synthetic Bacterial Community. The 10^th Asian Pacific Conference of Marine Biotechnology. Taipei, May 4-8

Wang Y, Danchin A, He LS. 2016. Symbiotic mycoplasmas from the stomach of deep-sea isopod bathynomus sp. The 5^th international workshop of Deep-sea microbiology. Kyoto, Japan.

​

Wang Y. and Leung F.C. 2003 An evaluation of new criteria for CpG islands in the genome as gene markers. The 11th International Conference on Intelligent Systems for Molecular Biology. 29 June – 3 July, Brisbane, Australia

Wang Y. Wang Z.G. and Leung F. C. 2006 A database for chicken full-length cDNAs.  Annual Meeting of Poultry Science Association, 2006, Edmonton, Canada

Wang Y., Yang J. K., O. O. Lee, S. C. K. Lau, T. Wong, Pei-Yuan Qian 2010 Brine-filled Atlantis II Deep in the Red Sea: A new hydrothermal ecosystem induces genetic isolation among bacterial inhabitants under compositional shifts. Annual Meeting of American Society of Microbiology, San Diego, US

Wang Y., Yang J. K., Lee O.O., Al-Suwailem A., Danchin A., Qian P.-Y. 2011, Bacterial lineage-specific genome expansion is coupled with highly frequent gene disruptions in the sediments in a deep-sea brine pool. The 4th Congress of European Microbiologists, 2011, Geneva, Switzerland

Lee O.O., H.C. Chung, J. Yang, Y. Wang, S. Dash, P.-Y. Qian. 2011. Microbial community and chemical profiles of natural biofilms dictate larval settlement preference of the barnacle Balanus amphitrite. The 4th Congress of European Microbiologists, Geneva, Switzerland

Wang Y. Zhaoming Gao, Pei-yuan Qian. 2015. Genomics of an Aerophobetes bacterium (CD12) indication of an anaerobic facultative lifestyle in cold seeps. The 14^th Deep Sea Biology Symposium. Aveiro, Portugal

Wang Yong, Gao Zhao-Ming, Pei-Yuan Qian, 2016. Archive of bacterial community in anhydrite crystals from a deep-sea basin provides evidence of past oil-spilling in a benthic environment in the Red Sea. The 16^th ISME international conference. Montreal, Canada.

Master students: Wu Yuzhi; Yuan Ke

PhD students: Cui Guojie; Huang Jiaomei; Li Wenli, Zhou Yingli, Li Qingmei