The proliferation and differentiation mechanism of neuroepithelial cell

The development mechanism of function of visual neural circuit

2000-2005   The Institute of Biophysics, Chinese Academy of  Sciences, Ph.D

1996-2000   Zhejiang University, B.S

2005 – 2010  Postdoctoral Fellow, Stowers Institute for Medical Research, USA.

2010 – 2013  Postdoctoral Fellow, The Department of Physiology, Development and  Neuroscience, University of Cambridge, UK 

2013 – Now  Investigator, the Laboratory of Stem Cells and Neurogenesis, The Institute  of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China

（1） Bipotent progenitors as embryonic origin of retinal stem cells, Journal of Cell Biology, 2017, Corresponding author.
（2） How Variable Clones Build an Invariable Retina, Neuron, 2012, the first author.
（3） Distinct Signals Conveyed by Pheromone Concentrations to the Mouse Vomeronasal Organ, Journal of Neuroscience, 2010, the first author.
（4） Encoding Gender and Individual Information in the Mouse Vomeronasal Organ, Science, 2008, the first author.

Brain complexity is implemented by astounding diversity of cell types connected in appropriate numbers and combinations. The precise control of neural progenitor/stem cell (NPC/NSC) division and differentiation is a prerequisite for the development and maintenance of circuit integrity, plasticity and regeneration. In the laboratory, our present interest is to develop various genetic and optical tools, by which we hope to gain access to the complete development from single stem (progenitor) cells to their progeny-derived neural circuits in distinct brain regions of zebrafish (Danio rerio), and thereby elucidating the fundamental logics underlying the determination of cell number, neuronal diversity, functional property of neural circuits.

已指导学生

徐佰杰  博士研究生  071006-神经生物学  

李艳  博士研究生  071006-神经生物学  

王梅  博士研究生  071006-神经生物学  

张慧  博士研究生  071006-神经生物学  

喻曙光  博士研究生  071006-神经生物学  

杜蕾  博士研究生  071006-神经生物学  

金梦梦  博士研究生  071006-神经生物学  

现指导学生

杨简  博士研究生  071006-神经生物学  

秦慧雯  博士研究生  071006-神经生物学  

李亚男  博士研究生  071006-神经生物学  

王晓鸥  博士研究生  071006-神经生物学  

陇兴涛  硕士研究生  071008-发育生物学