General

焦保卫 男   昆明动物研究所
Email: jiaobaowei@mail.kiz.ac.cn
Telephone:  0871-65191706
Address:  32 Jiaochang E. Road, Kunming, Yunnan
Postcode:  650223

Research Areas

1. Mammary gland stem cells and its application in breast cancer.

2. Imprinted genes functions in development and breast cancer.

3. LncRNA roles in breast cancer.

Education

-- Ph.D. in the Chinese University of Hong Kong.

Experience

Postdoctoral training in University of Massachusetts Medical School.

Work Experience
PI since 2013 in Kunming Institute of Zoology, CAS.

Honors & Distinctions

Young Talent of National 1000 Plan.

Publications

1.          Yang X, Wang H and Jiao B. Mammary gland stem cells and their application in breast cancer. Oncotarget. Accepted.

 

2.          Ke H, Zhao L, Feng X, Xu H, Zou L, Yang Q, Su X, Peng L, Jiao B. NEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548. Gene Regul Syst Bio. 2016 Apr 27;10(Suppl 1):11-7.

 

3.          Wu Y, Feng X, Gao L and Jiao B. Imprinted genes: important regulators in development. Hereditas(Beijing), 2016, 38(6): 508-22.

 

4.          Shin J., Wallingford MC, Gallant J., Marcho C., Jiao B., Byron M., Bossenz M., Lawrence JB, Jones S., Mager J. & Bach I. 2013 Rnf12/RLIM is dispensable for X chromosome inactivation in the mouse embryonic epiblast. Nature. 511(7507):86-9.

 

5.          Jiao B, Güngör C, Johnsen SA, Peters MA, Taniguchi-Ishigaki N, Chen YW, Riethdorf S, Drung A, Shin J, Pagnis R, Pantel K, Tachibana T, Lewis BC & Bach I. 2013. Nucleo-cytoplasmic shuttling regulates functional activity of Rnf12/RLIM. Mol Biol Cell. 2013 24(19):3085-96

 

6.          Jiao B., Ma H., Shokhirev M., Drung A., Yang Q., Shin J., Lu S., Byron M., Kalantry S., Mercurio AM, Lawrence JB, Hoffmann A. and Bach I. 2012. Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell. 149:630-41.

 

7.          Li MH, Wu FR, Gu Y, Wang TR, Wang H, Yang SJ, Sun YL, Zhou LY, Huang XG, Jiao B, Cheng CH, Wang DS. 2012. Insulin-Like Growth Factor 3 Regulates Expression of Genes Encoding Steroidogenic Enzymes and Key Transcription Factors in the Nile Tilapia Gonad. Biology of Reproduction. 86:163, 1-10.

 

8.          Shin J., Bossenz M., Chung Y., Ma H., Byron M., Taniguchi-Ishigaki N., Zhu X., Jiao B., Hall LL, Green MR, Jones SN, Hermans-Borgmeyer I, Lawrence JB and Bach I. 2010.  Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature. 467:977-81.

 

9.          Lin ZX, Jiao B., Che CT, Zuo Z, Mok CF, Zhao M, Ho WK, Tse WP, Lam KY, Fan RQ, Yang ZJ and Cheng CH. 2010. Ethyl acetate fraction of the root of Rubia cordifolia L. inhibits keratinocyte proliferation in vitro and promotes keratinocyte differentiation in vivo: potential application for psoriasis treatment. Phytotherapy Research. 24:1056-64.

 

10.      Jiao B., Yeung E.K.C., Chan C.B. and Cheng C.H.K. 2008. Establishment of a transgenic yeast screening system for estrogenicity and identification of the anti-estrogenic activity of malachite green. Journal of Cellular Biochemistry. 105:1399-409.

 

11.      Zhang Y., Liu Y., Huang X., Liu X., Jiao B., Meng Z., Zhu P., Li S., Lin H. and Cheng C.H.K. 2008. Two alternatively spliced GPR39 transcripts in seabream: molecular cloning, genomic organization, and regulation of gene expression by metabolic signals. Journal of Endocrinology. 199: 457-70.

 

12.      Jiao B. and Cheng C.H.K. 2010. Disrupting actions of bisphenol A and malachite green on growth hormone receptor gene expression and signal transduction in seabream. Fish Physiology and Biochemistry. 36:251-61.

 

13.      Wang D.S., Jiao B.*, Hu C., Huang X., Liu Z. and Cheng C.H.K. 2008. Discovery of a gonad-specific IGF subtype in teleost, Biochemical and Biophysical Research Communications. 367, 336-41.

 

14.      Huang X., Jiao B.*, Fung K.K., Zhang Y., Chan C. B., Lin H., Wang D.S. and Cheng C.H.K. 2007. The presence of two distinct prolactin receptors with different signal pathways and constructive expression pattern under the stimulation of steroid hormones in teleost. Journal of Endocrinology. 194, 373-92.

 

15.​      Liu Z., Wu F., Jiao B.*, Zhang X., Hu C., Huang B., Zhou L., Huang X., Wang Z., Zhang Y., Nagahama Y., Cheng C.H.K. and Wang D.S. 2007. Molecular cloning of Dmrt1, Foxl2 and Cyp19 in Southern catfish and their possible roles in sex differentiation. Journal of Endocrinology 194, 223-41.


16.   Jiao B., Huang X., Chan C.B., Zhang L., Wang D.S. and Cheng C.H.K. 2006. The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream. Journal of Molecular Endocrinology 36, 23-40.


Students

现指导学生

赵丽敏  硕士研究生  071009-细胞生物学  

柯浩  博士研究生  071009-细胞生物学  

杨星  硕士研究生  071009-细胞生物学  

赵丽娜  博士研究生  071009-细胞生物学  

马玉洁  硕士研究生  071009-细胞生物学