基本信息
李洁  女  硕导  中国科学院微生物研究所
电子邮件: lijie824@im.ac.cn
通信地址: 北京朝阳区北辰西路1号院3号
邮政编码:

招生信息

   
招生专业
071005-微生物学
招生方向
甲烷古菌环境适应与转录后调控

工作经历

   
工作简历
2017-10~2019-05,中国科学院微生物研究所, 副研究员
2010-07~2017-09,中国科学院微生物研究所, 助理研究员

出版信息

   
发表论文
(1) Genome-wide mRNA processing in methanogenic archaea reveals post-transcriptional regulation of ribosomal protein synthesis, Nucleic Acids Research, 2017, 通讯作者
(2) New molecular insights into an archaeal RNase J reveal a conserved processive exoribonucleolysis mechanism of the RNase J family, Molecular Microbiology, 2017, 通讯作者
(3) Conserved TRAM Domain Functions as an Archaeal Cold Shock Protein via RNA Chaperone Activity, Frontiers in Microbiology, 2017, 通讯作者
(4) Global mapping transcriptional start sites revealed both transcriptional and post-transcriptional regulation of cold adaptation in the methanogenic archaeon Methanolobus psychrophilus, Scientific Reports, 2015, 第 1 作者
(5) Characterization of an Archaeal Two-Component System That Regulates Methanogenesis in Methanosaeta harundinacea, PLOS one, 2015, 第 1 作者
(6) Mechanism for Stabilizing mRNAs Involved in Methanol-Dependent Methanogenesis of Cold-Adaptive Methanosarcina mazei zm-15, Applied and Environmental Microbiology, 2014, 第 2 作者
(7) Acyl homoserine lactone-based quorum sensing in a methanogenic archaeon, The ISME Journal, 2012, 第 4 作者
(8) Identification and Characterization of the Cognate Anti- Sigma Factor and Specific Promoter Elements of a T. tengcongensis ECF Sigma Factor, PLOS one, 2012, 第 2 作者
(9) Functional evaluation of four putative DNA-binding regions in Thermoanaerobacter tengcongensis reverse gyrase, Extremophiles, 2011, 第 1 作者
(10) Two Distantly Homologous DnaG Primases from Thermoanaerobacter tengcongensis Exhibit Distinct Initiation Specificities and Priming Activities, JOURNAL OF BACTERIOLOGY, 2010, 第 1 作者
(11) Mechanism for the TtDnaA–Tt-oriC cooperative interaction at high temperature and duplex opening at an unusual AT-rich region in Thermoanaerobacter tengcongensis, Nucleic Acids Research, 2007, 第 3 作者

科研活动

   
科研项目
( 1 ) 古菌RNA加工流转关键酶生理生化功能及分子机制, 主持, 国家级, 2017-01--2020-12
( 2 ) 青藏高原湿地低温甲烷代谢途径及其功能产甲烷菌的温度适应机制, 参与, 国家级, 2018-01--2021-12
( 3 ) 低温甲烷古菌对冷胁迫的转录后响应机制, 参与, 国家级, 2015-01--2019-12