Protein PTMs

 Glycosylation 

Protein Carbonylation

2013.07-2018.06, Dalian Institute of Chemical Physics, Associate Professor

2018.07-Now, Dalian Institute of Chemical Physics, Professor

（1） A New Searching Strategy for the Identification of O-Linked Glycopeptides, Analytical Chemistry, 2019, 第 3 作者
（2） Proteomics Analysis of Site-specific Glycoforms by a Virtual Multistage Mass Spectrometry Metho, Analytica Chimica Acta, 2019, 第 1 作者
（3） LCN1 is highly expressed in cholangiocarcinoma patients and indicates poor prognosis, INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 第 4 作者
（4） Highly Efficient Identification of O-GalNAc Glycosylation by an Acid-Assisted Glycoform Simplification Approach, Proteomics, 2018, 第 1 作者
（5） Recent advances in methods for the analysis of protein o-glycosylation at proteome level, JOURNAL OF SEPARATION SCIENCE, 2018, 第 2 作者
（6） Caffeic acid phenethyl ester (CAPE) revisited: Covalent modulation of XPO1/CRM1 activities and implication for its mechanism of action, CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 第 3 作者
（7） In-Depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge, ANALYTICAL CHEMISTRY, 2017, 第 1 作者
（8） Proteomics Analysis of O-GaINAc Glycosylation in Human Serum by an Integrated Strategy, ANALYTICAL CHEMISTRY, 2017, 第 1 作者
（9） Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer, ONCOTARGET, 2016, 第 1 作者
（10） Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1 beta Producing Inflammasome, ACS Nano，, 2014, 第 3 作者
（11） Layer-by-layer assembly of multilayer polysaccharide coated magnetic nanoparticles for the selective enrichment of glycopeptides，, Chem. Commun., 2013, 第 2 作者
（12） Facile synthesis of yolk-shell magnetic mesoporous carbon microspheres for efficient enrichment of low abundance peptides, Nanoscale, 2013, 第 2 作者
（13） Facile preparation of ordered mesoporous silica-carbon composite nanoparticles for glycan enrichment, CHEMICAL COMMUNICATIONS, 2013, 第 1 作者
（14） Phosphoric acid functionalized mesoporous organo-silica (EPO) as the adsorbent for in situ enrichment and isotope labeling of endogenous phosphopeptides, Chem. Commun., 2012, 第 1 作者
（15）  Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation, Chem. Commun., 2012, 第 1 作者
（16） A poly(ethylene glycol)-brush decorated magnetic polymer for highly specific enrichment of phosphopeptides, Chem. Sci, 2012, 第 2 作者
（17） Highly Efficient Extraction of Serum Peptides by Ordered Mesoporous Carbon, Angew. Chem. Int. Ed., 2011, 第 1 作者
（18） Size-Selective Enrichment of N-Linked Glycans Using Highly Ordered Mesoporous Carbon Material and Detection by MALDI-TOF MS, Anal. Chem., 2011, 第 1 作者

现指导学生

周家华  博士研究生  070302-分析化学  

刘莉  硕士研究生  070302-分析化学  

王佳怡  硕士研究生  070302-分析化学  

陈尧  博士研究生  070302-分析化学