基本信息
孟令红 女 硕导 中国科学院海洋研究所
电子邮件： menglh@ms.qdio.ac.cn
通信地址： 山东省青岛市市南区南海路7号
邮政编码：
电子邮件： menglh@ms.qdio.ac.cn
通信地址： 山东省青岛市市南区南海路7号
邮政编码：
研究领域
1.海洋天然产物结构多样性与生物活性研究
2.海洋真菌次级代谢调控
教育背景
2010-09--2015-07 中国科学院海洋研究所 博士学位
2006-09--2010-07 山东大学 学士学位
2006-09--2010-07 山东大学 学士学位
工作经历
工作简历
2021-08~2022-08,东京大学, 访问学者
2018-10~现在, 中国科学院海洋研究所, 特聘研究员
2018-01~现在, 中国科学院海洋研究所, 副研究员
2015-08~2017-12,中国科学院海洋研究所, 助理研究员
2018-10~现在, 中国科学院海洋研究所, 特聘研究员
2018-01~现在, 中国科学院海洋研究所, 副研究员
2015-08~2017-12,中国科学院海洋研究所, 助理研究员
教授课程
海洋有机物提取与解谱技术
专利与奖励
奖励信息
（1） 海洋植物源内生真菌活性物质研究, 二等奖, 省级, 2020
（2） 汇泉青年学者, 研究所（学校）, 2018
（3） 中国科学院青年创新促进会会员, 院级, 2017
（4） 山东省优秀博士论文, 一等奖, 省级, 2016
（5） 中国科学院院长特别奖, 特等奖, 院级, 2015
（2） 汇泉青年学者, 研究所（学校）, 2018
（3） 中国科学院青年创新促进会会员, 院级, 2017
（4） 山东省优秀博士论文, 一等奖, 省级, 2016
（5） 中国科学院院长特别奖, 特等奖, 院级, 2015
专利成果
[1] 孟令红, 王莹, 李晓明, 王斌贵. 一种马来酸酐脂环类化合物及其制备方法和应用. CN: CN114891017A, 2022-08-12.
[2] 孟令红, 王莹, 李晓明, 王斌贵. 一种马来酸酐脂环类化合物及其制备方法和应用. CN: CN114891017B, 2023-08-22.
[3] 王斌贵, 胡雪怡, 李晓明, 孟令红. 一种混源萜类化合物及其制备方法和应用. CN: CN116514754A, 2023-08-01.
[4] 王斌贵, 胡雪怡, 李晓明, 孟令红, 李鑫. 一种细胞松弛素类化合物及其制备方法和应用. CN: CN113861208A, 2021-12-31.
[5] 王斌贵, 张凡忠, 孟令红, 李晓明, 杨遂群. 一种硫代大环内酯化合物及其制备方法和抗水产病害菌活性应用. CN: CN109467546A, 2019-03-15.
[6] 王斌贵, 李洪雷, 李晓明, 孟令红. 羟基蒽醌类衍生物及其应用. CN: CN106478399A, 2017-03-08.
[7] 王斌贵, 孟令红, 李晓明. 硫代二酮哌嗪类化合物及其应用. CN: CN106397459A, 2017-02-15.
[8] 王斌贵, 李洪雷, 孟令红, 李晓明. 一种具有抗氧化活性的二苯甲酮类化合物及其制备方法和应用. CN: CN107586721A, 2018-01-16.
[9] 王斌贵, 孟令红, 李晓明. 一种三环系倍半萜类化合物及其制备方法和用途. CN: CN104277982A, 2015-01-14.
[10] 王斌贵, 孟令红, 黄才国, 李晓明. 硫代二酮哌嗪类化合物及其制备方法和用途. CN: CN104804020A, 2015-07-29.
[11] 王斌贵, 孟令红, 黄才国, 吕翠婷, 李晓明, 李春顺, 徐刚明. 一种弯孢霉菌素类衍生物及其制备方法和应用. CN: CN103435590A, 2013-12-11.
[12] 王斌贵, 李洪雷, 李晓明, 孟令红. 羟基蒽醌类衍生物及其应用. CN: CN1727327A, 2006-02-01.
[2] 孟令红, 王莹, 李晓明, 王斌贵. 一种马来酸酐脂环类化合物及其制备方法和应用. CN: CN114891017B, 2023-08-22.
[3] 王斌贵, 胡雪怡, 李晓明, 孟令红. 一种混源萜类化合物及其制备方法和应用. CN: CN116514754A, 2023-08-01.
[4] 王斌贵, 胡雪怡, 李晓明, 孟令红, 李鑫. 一种细胞松弛素类化合物及其制备方法和应用. CN: CN113861208A, 2021-12-31.
[5] 王斌贵, 张凡忠, 孟令红, 李晓明, 杨遂群. 一种硫代大环内酯化合物及其制备方法和抗水产病害菌活性应用. CN: CN109467546A, 2019-03-15.
[6] 王斌贵, 李洪雷, 李晓明, 孟令红. 羟基蒽醌类衍生物及其应用. CN: CN106478399A, 2017-03-08.
[7] 王斌贵, 孟令红, 李晓明. 硫代二酮哌嗪类化合物及其应用. CN: CN106397459A, 2017-02-15.
[8] 王斌贵, 李洪雷, 孟令红, 李晓明. 一种具有抗氧化活性的二苯甲酮类化合物及其制备方法和应用. CN: CN107586721A, 2018-01-16.
[9] 王斌贵, 孟令红, 李晓明. 一种三环系倍半萜类化合物及其制备方法和用途. CN: CN104277982A, 2015-01-14.
[10] 王斌贵, 孟令红, 黄才国, 李晓明. 硫代二酮哌嗪类化合物及其制备方法和用途. CN: CN104804020A, 2015-07-29.
[11] 王斌贵, 孟令红, 黄才国, 吕翠婷, 李晓明, 李春顺, 徐刚明. 一种弯孢霉菌素类衍生物及其制备方法和应用. CN: CN103435590A, 2013-12-11.
[12] 王斌贵, 李洪雷, 李晓明, 孟令红. 羟基蒽醌类衍生物及其应用. CN: CN1727327A, 2006-02-01.
出版信息
发表论文
[1] Angewandte Chemie International Edition. 2024, 第 1 作者
[2] Journal of Natural Products. 2024, 通讯作者
[3] Bioorganic Chemistry. 2024, 通讯作者
[4] Beilstein Journal of Organic Chemistry. 2024, 通讯作者
[5] Chinese Chemical Letters. 2023, 通讯作者
[6] Ying, Zhen, Li, XiaoMing, Wang, BinGui, Li, HongLei, Meng, LingHong. Rubensteroid A, a new steroid with antibacterial activity from Penicillium rubens AS-130. JOURNAL OF ANTIBIOTICS. 2023, 第 5 作者 通讯作者 http://dx.doi.org/10.1038/s41429-023-00634-x.
[7] Li, YanHe, Mandi, Attila, Li, HongLei, Li, XiaoMing, Li, Xin, Meng, LingHong, Yang, SuiQun, Shi, XiaoShan, Kurtan, Tibor, Wang, BinGui. Isolation and characterization of three pairs of verrucosidin epimers from the marine sediment-derived fungus Penicillium cyclopium and configuration revision of penicyrone A and related analogues. MARINE LIFE SCIENCE & TECHNOLOGY[J]. 2023, 第 6 作者5(2): 223-231, http://dx.doi.org/10.1007/s42995-023-00173-2.
[8] Yang, SuiQun, Song, Qi, Li, XiaoMing, Li, Xin, Li, HongLei, Meng, LingHong, Wang, BinGui. Antimicrobial polyketides and sesquiterpene lactones from the deep-sea cold-seep-derived fungus Talaromyces minioluteus CS-113 triggered by the histone deacetylase inhibitor SAHA. ORGANIC & BIOMOLECULAR CHEMISTRY. 2023, 第 6 作者http://dx.doi.org/10.1039/d3ob00058c.
[9] Ying, Zhen, Li, XiaoMing, Yang, SuiQun, Wang, BinGui, Li, HongLei, Meng, LingHong. New Polyketide and Sesquiterpenoid Derivatives from the Magellan Seamount-Derived Fungus Penicillium rubens AS-130. CHEMISTRY & BIODIVERSITY. 2023, 第 6 作者 通讯作者 20(4): http://dx.doi.org/10.1002/cbdv.202300229.
[10] Ying, Zhen, Li, XiaoMing, Yang, SuiQun, Wang, BinGui, Li, HongLei, Meng, LingHong. New Polyketide and Sesquiterpenoid Derivatives from the Magellan Seamount-Derived Fungus Penicillium rubens AS-130. CHEMISTRY & BIODIVERSITY[J]. 2023, 第 6 作者 通讯作者 20(4): http://dx.doi.org/10.1002/cbdv.202300229.
[11] Zhang, FanZhong, Li, XiaoMing, Meng, LingHong, Wang, BinGui. A new steroid with potent antimicrobial activities and two new polyketides from Penicillium variabile EN-394, a fungus obtained from the marine red alga Rhodomela confervoides. JOURNAL OF ANTIBIOTICS. 2023, 第 3 作者 通讯作者 http://dx.doi.org/10.1038/s41429-023-00666-3.
[12] Li, YanHe, Mandi, Attila, Li, HongLei, Li, XiaoMing, Li, Xin, Meng, LingHong, Yang, SuiQun, Shi, XiaoShan, Kurtan, Tibor, Wang, BinGui. Isolation and characterization of three pairs of verrucosidin epimers from the marine sediment-derived fungus Penicillium cyclopium and configuration revision of penicyrone A and related analogues. MARINE LIFE SCIENCE & TECHNOLOGY[J]. 2023, 第 6 作者5(2): 223-231, http://dx.doi.org/10.1007/s42995-023-00173-2.
[13] Hu, XueYi, Li, XiaoMing, Yang, SuiQun, Wang, BinGui, Meng, LingHong. New Cytochalasin Derivatives from Deep-Sea Cold Seep-Derived Endozoic Fungus Curvularia verruculosa CS-129. CHEMISTRY & BIODIVERSITY[J]. 2022, 第 5 作者 通讯作者 19(8): http://dx.doi.org/10.1002/cbdv.202200550.
[14] Du, FengYu, Mandi, Attila, Li, XiaoMing, Meng, LingHong, Kurtan, Tibor, Wang, BinGui. Experimental and Computational Analysis of the Solution and Solid-State Conformations of Hexadepsipeptides from Beauveria felina. CHINESE JOURNAL OF CHEMISTRY[J]. 2022, 第 4 作者40(3): 378-384, http://dx.doi.org/10.1002/cjoc.202100586.
[15] Hu, XueYi, Li, XiaoMing, Wang, BinGui, Meng, LingHong. Uncommon Polyketides from Penicillium steckii AS-324, a Marine Endozoic Fungus Isolated from Deep-Sea Coral in the Magellan Seamount. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 第 4 作者 通讯作者 23(11): http://dx.doi.org/10.3390/ijms23116332.
[16] Ying Wang, XiaoMing Li, SuiQun Yang, FanZhong Zhang, BinGui Wang, HongLei Li, LingHong Meng. Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa. MARINE DRUGS[J]. 2022, 第 7 作者 通讯作者 20(3):
[17] Hu, XueYi, Li, XiaoMing, Wang, BinGui, Meng, LingHong. Tanzawaic Acid Derivatives: Fungal Polyketides from the Deep-Sea Coral-Derived Endozoic Penicillium steckii AS-324. JOURNAL OF NATURAL PRODUCTS[J]. 2022, 第 4 作者 通讯作者 85(5): 1398-1406, http://dx.doi.org/10.1021/acs.jnatprod.2c00211.
[18] Shi, XiaoShan, Song, YinPing, Meng, LingHong, Yang, SuiQun, Wang, DunJia, Zhou, XingWang, Ji, NaiYun, Wang, BinGui, Li, XiaoMing. Isolation and Characterization of Antibacterial Carotane Sesquiterpenes from Artemisia argyi Associated Endophytic Trichoderma virens QA-8. ANTIBIOTICS-BASEL[J]. 2021, 第 3 作者10(2): http://dx.doi.org/10.3390/antibiotics10020213.
[19] Du, FengYu, Mandi, Attila, Li, XiaoMing, Meng, LingHong, Kurtan, Tibor, Wang, BinGui. Experimental and Computational Analysis of the Solution and Solid-State Conformations of Hexadepsipeptides from Beauveria felina. CHINESE JOURNAL OF CHEMISTRY[J]. 2021, 第 4 作者7,
[20] Hu, XueYi, Wang, ChenYin, Li, XiaoMing, Yang, SuiQun, Li, Xin, Wang, BinGui, Si, ShuYi, Meng, LingHong. Cytochalasin Derivatives from the Endozoic Curvularia verruculosa CS-129, a Fungus Isolated from the Deep-Sea Squat Lobster Shinkaia crosnieri Living in the Cold Seep Environment. JOURNAL OF NATURAL PRODUCTS[J]. 2021, 第 8 作者 通讯作者 84(12): 3122-3130, http://dx.doi.org/10.1021/acs.jnatprod.1c00907.
[21] Shi, XiaoShan, Li, HongLei, Li, XiaoMing, Wang, DunJia, Li, Xin, Meng, LingHong, Zhou, XingWang, Wang, BinGui. Highly oxygenated polyketides produced by Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the fresh roots of the medicinal plant Artemisia argyi. BIOORGANIC CHEMISTRY[J]. 2020, 第 6 作者94: http://dx.doi.org/10.1016/j.bioorg.2019.103448.
[22] Meng, LingHong, Li, XiaoMing, Li, HongLei, Wang, BinGui. Chermebilaenes A and B, New Bioactive Meroterpenoids from Co-Cultures of Marine-Derived Isolates ofPenicillium bilaiaeMA-267 andPenicillium chermesinumEN-480. MARINE DRUGS[J]. 2020, 第 1 作者 通讯作者 18(7): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000554187500001.
[23] Du, FengYu, Li, XiaoMing, Sun, ZeChun, Meng, LingHong, Wang, BinGui. Secondary Metabolites with Agricultural Antagonistic Potentials from Beauveria felina, a Marine-Derived Entomopathogenic Fungus. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2020, 第 4 作者68(50): 14824-14831, http://dx.doi.org/10.1021/acs.jafc.0c05696.
[24] Zhang, FanZhong, Li, XiaoMing, Meng, LingHong, Wang, BinGui. Cladocladosin A, an unusual macrolide with bicyclo 5/9 ring system, and two thiomacrolides from the marine mangrove-derived endophytic fungus, Cladosporium cladosporioides MA-299. BIOORGANIC CHEMISTRY[J]. 2020, 第 3 作者 通讯作者 101: http://dx.doi.org/10.1016/j.bioorg.2020.103950.
[25] Hu, Xueyi, Li, Xiaoming, Meng, Linghong, Wang, Bingui. Antioxidant bisabolane-type sesquiterpenoids from algal-derived fungusAspergillus sydowiiEN-434. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2020, 第 3 作者 通讯作者 38(5): 1532-1536, http://lib.cqvip.com/Qikan/Article/Detail?id=7102940543.
[26] Hu, XueYi, Li, XiaoMing, Yang, SuiQun, Liu, Hui, Meng, LingHong, Wang, BinGui. Three New Sesquiterpenoids from the Algal-Derived Fungus Penicillium chermesinum EN-480. MARINE DRUGS[J]. 2020, 第 5 作者 通讯作者 18(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000533909300047.
[27] Shi, XiaoShan, Meng, LingHong, Li, Xin, Wang, DunJia, Zhou, XingWang, Du, FengYu, Wang, BinGui, Li, XiaoMing. Polyketides and Terpenoids with Potent Antibacterial Activities from the Artemisia argyi-Derived Fungus Trichoderma koningiopsis QA-3. CHEMISTRY & BIODIVERSITY[J]. 2020, 第 2 作者17(11): https://www.webofscience.com/wos/woscc/full-record/WOS:000584000700001.
[28] Wang, YaNan, Meng, LingHong, Wang, BinGui. Progress in Research on Bioactive Secondary Metabolites from Deep-Sea Derived Microorganisms. MARINE DRUGS[J]. 2020, 第 2 作者 通讯作者 18(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761599/.
[29] Lu, Fengyi, Li, Xiaoming, Chi, Luping, Meng, Linghong, Wang, Bingui. A new acyclic peroxide fromAspergillus nidulansSD-531, a fungus obtained from deep-sea sediment of cold spring in the South China Sea. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2020, 第 4 作者38(4): 1225-1232, http://lib.cqvip.com/Qikan/Article/Detail?id=7102292174.
[30] Meng, LingHong, Li, XiaoMing, Zhang, FanZhong, Wang, YaNan, Wang, BinGui. Talascortenes A-G, Highly Oxygenated Diterpenoid Acids from the Sea-Anemone-Derived Endozoic Fungus Talaromyces scorteus AS-242. JOURNAL OF NATURAL PRODUCTS[J]. 2020, 第 1 作者 通讯作者 83(8): 2528-2536, https://www.webofscience.com/wos/woscc/full-record/WOS:000566765000024.
[31] Zhang, FanZhong, Li, XiaoMing, Li, Xin, Yang, SuiQun, Meng, LingHong, Wang, BinGui. Polyketides from the Mangrove-Derived Endophytic Fungus Cladosporium cladosporioides. MARINE DRUGS[J]. 2019, 第 5 作者 通讯作者 17(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000470964600049.
[32] Zhang, FanZhong, Li, XiaoMing, Yang, SuiQun, Meng, LingHong, Wang, BinGui. Thiocladospolides A-D, 12-Membered Macrolides from the Mangrove-Derived Endophytic Fungus Cladosporium cladosporioides MA-299 and Structure Revision of Pandangolide 3. JOURNAL OF NATURAL PRODUCTS[J]. 2019, 第 4 作者 通讯作者 82(6): 1535-1541, https://www.webofscience.com/wos/woscc/full-record/WOS:000473827300017.
[33] Li, HongLei, Li, XiaoMing, Yang, SuiQun, Meng, LingHong, Li, Xin, Wang, BinGui. Prenylated Phenol and Benzofuran Derivatives from Aspergillus terreus EN-539, an Endophytic Fungus Derived from Marine Red Alga Laurencia okamurai. MARINE DRUGS[J]. 2019, 第 4 作者17(11): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000502262200049.
[34] Cao, Jin, Li, XiaoMing, Li, Xin, Li, HongLei, Meng, LingHong, Wang, BinGui. New lactone and isocoumarin derivatives from the marine mangrove-derived endophytic fungus Penicillium coffeae MA-314. PHYTOCHEMISTRY LETTERS[J]. 2019, 第 5 作者32: 1-5, http://dx.doi.org/10.1016/j.phytol.2019.04.018.
[35] Shi, XiaoShan, Meng, LingHong, Li, XiaoMing, Li, Xin, Wang, DunJia, Li, HongLei, Zhou, XingWang, Wang, BinGui. Trichocadinins B-G: Antimicrobial Cadinane Sesquiterpenes from Trichoderma virens QA-8, an Endophytic Fungus Obtained from the Medicinal Plant Artemisia argyi. JOURNAL OF NATURAL PRODUCTS[J]. 2019, 第 2 作者82(9): 2470-2476, http://ir.qdio.ac.cn/handle/337002/163419, http://www.irgrid.ac.cn/handle/1471x/6861263, http://ir.qdio.ac.cn/handle/337002/163420, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488424000012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[36] Cao, Jin, Li, XiaoMing, Meng, LingHong, Konuklugil, Belma, Li, Xin, Li, HongLei, Wang, BinGui. Isolation and characterization of three pairs of indolediketopiperazine enantiomers containing infrequent N-methoxy substitution from the marine algal-derived endophytic fungus Acrostalagmus luteoalbus TK-43. BIOORGANIC CHEMISTRY[J]. 2019, 第 3 作者90: 103030, http://dx.doi.org/10.1016/j.bioorg.2019.103030.
[37] Yang, SuiQun, Li, XiaoMing, Li, Xin, Li, HongLei, Meng, LingHong, Wang, BinGui. New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535. PHYTOCHEMISTRY LETTERS[J]. 2018, 第 5 作者25: 191-195, http://dx.doi.org/10.1016/j.phytol.2018.04.023.
[38] Jiang, Wenli, Meng, Linghong, Xu, Guangming, Lv, Cuiting, Wang, Hongliang, Tian, He, Chen, Ruohua, Jiao, Binghua, Wang, Bingui, Huang, Caiguo. Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer. ONCOLOGY LETTERS[J]. 2018, 第 2 作者16(5): 6445-6457, http://dx.doi.org/10.3892/ol.2018.9486.
[39] Li, HongLei, Xu, Rui, Li, XiaoMing, Yang, SuiQun, Meng, LingHong, Wang, BinGui. Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332. ORGANIC LETTERS[J]. 2018, 第 5 作者20(5): 1465-1468, https://www.webofscience.com/wos/woscc/full-record/WOS:000426804200049.
[40] Xu, Gangming, Yang, Suiqun, Meng, Linghong, Wang, BinGui. The plant hormone abscisic acid regulates the growth and metabolism of endophytic fungus Aspergillus nidulans. SCIENTIFIC REPORTS[J]. 2018, 第 3 作者8(1): https://doaj.org/article/8404ac005c1344cdb1ac9953af1d0662.
[41] 罗寒, 李晓栋, 李晓明, 刘洋, 孟令红, 王斌贵. 红树林来源内生真菌杂色曲霉Aspergillus versicolor MA-229次级代谢产物研究. 中国抗生素杂志[J]. 2017, 第 5 作者42(4): s14-s20, http://lib.cqvip.com/Qikan/Article/Detail?id=671862672.
[42] Shi, XiaoShan, Wang, DunJia, Li, XiaoMing, Li, HongLei, Meng, LingHong, Li, Xin, Pi, Yan, Zhou, XingWang, Wang, BinGui. Antimicrobial polyketides from Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the medicinal plant Artemisia argyi. RSC ADVANCES[J]. 2017, 第 5 作者7(81): 51335-51342, http://ir.qdio.ac.cn/handle/337002/157272.
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[37] Yang, SuiQun, Li, XiaoMing, Li, Xin, Li, HongLei, Meng, LingHong, Wang, BinGui. New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535. PHYTOCHEMISTRY LETTERS[J]. 2018, 第 5 作者25: 191-195, http://dx.doi.org/10.1016/j.phytol.2018.04.023.
[38] Jiang, Wenli, Meng, Linghong, Xu, Guangming, Lv, Cuiting, Wang, Hongliang, Tian, He, Chen, Ruohua, Jiao, Binghua, Wang, Bingui, Huang, Caiguo. Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer. ONCOLOGY LETTERS[J]. 2018, 第 2 作者16(5): 6445-6457, http://dx.doi.org/10.3892/ol.2018.9486.
[39] Li, HongLei, Xu, Rui, Li, XiaoMing, Yang, SuiQun, Meng, LingHong, Wang, BinGui. Simpterpenoid A, a Meroterpenoid with a Highly Functionalized Cyclohexadiene Moiety Featuring gem-Propane-1,2-dione and Methylformate Groups, from the Mangrove-Derived Penicillium simplicissimum MA-332. ORGANIC LETTERS[J]. 2018, 第 5 作者20(5): 1465-1468, https://www.webofscience.com/wos/woscc/full-record/WOS:000426804200049.
[40] Xu, Gangming, Yang, Suiqun, Meng, Linghong, Wang, BinGui. The plant hormone abscisic acid regulates the growth and metabolism of endophytic fungus Aspergillus nidulans. SCIENTIFIC REPORTS[J]. 2018, 第 3 作者8(1): https://doaj.org/article/8404ac005c1344cdb1ac9953af1d0662.
[41] 罗寒, 李晓栋, 李晓明, 刘洋, 孟令红, 王斌贵. 红树林来源内生真菌杂色曲霉Aspergillus versicolor MA-229次级代谢产物研究. 中国抗生素杂志[J]. 2017, 第 5 作者42(4): s14-s20, http://lib.cqvip.com/Qikan/Article/Detail?id=671862672.
[42] Shi, XiaoShan, Wang, DunJia, Li, XiaoMing, Li, HongLei, Meng, LingHong, Li, Xin, Pi, Yan, Zhou, XingWang, Wang, BinGui. Antimicrobial polyketides from Trichoderma koningiopsis QA-3, an endophytic fungus obtained from the medicinal plant Artemisia argyi. RSC ADVANCES[J]. 2017, 第 5 作者7(81): 51335-51342, http://ir.qdio.ac.cn/handle/337002/157272.
[43] Li, HongLei, Li, XiaoMing, Li, Xin, Wang, ChenYin, Liu, Hui, Kassack, Matthias U, Meng, LingHong, Wang, BinGui. Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501. JOURNAL OF NATURAL PRODUCTS[J]. 2017, 第 7 作者 通讯作者 80(1): 162-168, http://ir.qdio.ac.cn/handle/337002/157266.
[44] Li HongLei, Li XiaoMing, Li Xin, Wang ChenYin, Liu Hui, Kassack Matthias U, Meng LingHong, Wang BinGui. Antioxidant Hydroanthraquinones from the Marine Algal-Derived Endophytic Fungus Talaromyces islandicus EN-501. JOURNAL OF NATURAL PRODUCTS[J]. 2017, 第 7 作者
[45] Meng, LingHong, Li, XiaoMing, Liu, Yang, Xu, GangMing, Wang, BinGui. Antimicrobial alkaloids produced by the mangrove endophyte Penicillium brocae MA-231 using the OSMAC approach. RSC ADVANCES[J]. 2017, 第 1 作者7(87): 55026-55033, http://ir.qdio.ac.cn/handle/337002/157391.
[46] Hu, XueYi, Meng, LingHong, Li, Xin, Yang, SuiQun, Li, XiaoMing, Wang, BinGui. Three New Indole Diterpenoids from the Sea-Anemone-Derived Fungus Penicillium sp AS-79. MARINE DRUGS[J]. 2017, 第 2 作者15(5): http://ir.qdio.ac.cn/handle/337002/137147.
[47] Meng, LingHong, Chen, HuiQin, Form, Imke, Konuklugil, Belma, Proksch, Peter, Wang, BinGui. New Chromone, Isocoumarin, and Indole Alkaloid Derivatives from three Sponge-derived Fungal Strains. NATURAL PRODUCT COMMUNICATIONS[J]. 2016, 第 1 作者11(9): 1293-1296, https://www.webofscience.com/wos/woscc/full-record/WOS:000384513600027.
[48] Meng, LingHong, Wang, ChenYin, Mandi, Attila, Li, XiaoMing, Hu, XueYi, Kassack, Matthias U, Kurtan, Tibor, Wang, BinGui. Three Diketopiperazine Alkaloids with Spirocyclic Skeletons and One Bisthiodiketopiperazine Derivative from the Mangrove-Derived Endophytic Fungus Penicillium brocae MA-231. ORGANICLETTERS[J]. 2016, 第 1 作者18(20): 5304-5307, https://www.webofscience.com/wos/woscc/full-record/WOS:000386187300030.
[49] Li, HongLei, Li, XiaoMing, Liu, Hui, Meng, LingHong, Wang, BinGui. Two New Diphenylketones and a New Xanthone from Talaromyces islandicus EN-501, an Endophytic Fungus Derived from the Marine Red Alga Laurencia okamurai. MARINE DRUGS[J]. 2016, 第 4 作者 通讯作者 14(12): http://ir.qdio.ac.cn/handle/337002/157263.
[50] Li, XiaoDong, Li, Xin, Li, XiaoMing, Xu, GangMing, Zhang, Peng, Meng, LingHong, Wang, BinGui. Tetranorlabdane Diterpenoids from the Deep Sea Sediment-Derived Fungus Aspergillus wentii SD-310. PLANTA MEDICA[J]. 2016, 第 6 作者82(9-10): 877-881, http://ir.qdio.ac.cn/handle/337002/157251.
[51] Meng, LingHong, Mandi, Attila, Li, XiaoMing, Liu, Yang, Kurtan, Tibor, Wang, BinGui. Isolation, Stereochemical Study, and Antioxidant Activity of Benzofuranone Derivatives from a Mangrove-derived Fungus Eurotium rubrum MA-150. CHIRALITY[J]. 2016, 第 1 作者28(8): 581-584, http://www.corc.org.cn/handle/1471x/2375120.
[52] Meng, LingHong, Zhang, Peng, Li, XiaoMing, Wang, BinGui. Penicibrocazines A-E, Five New Sulfide Diketopiperazines from the Marine-Derived Endophytic Fungus Penicillium brocae. MARINE DRUGS[J]. 2015, 第 1 作者13(1): 276-287, https://doaj.org/article/e7d45244cd054cbaa1013953a197196e.
[53] Liu, Yang, Li, XiaoMing, Meng, LingHong, Jiang, WenLi, Xu, GangMing, Huang, CaiGuo, Wang, BinGui. Bisthiodiketopiperazines and Acorane Sesquiterpenes Produced by the Marine-Derived Fungus Penicillium adametzioides AS-53 on Different Culture Media. JOURNAL OF NATURAL PRODUCTS[J]. 2015, 第 3 作者78(6): 1294-1299, http://dx.doi.org/10.1021/acs.jnatprod.5b00102.
[54] Liu, Yang, Mandi, Attila, Li, XiaoMing, Meng, LingHong, Kurtan, Tibor, Wang, BinGui. Peniciadametizine A, a Dithiodiketopiperazine with a Unique Spirofuran-2,7 '-pyrazino1,2-b1,2oxazine Skeleton, and a Related Analogue, Peniciadametizine B, from the Marine Sponge-Derived Fungus Penicillium adametzioides. MARINEDRUGS[J]. 2015, 第 4 作者13(6): 3640-3652, http://dx.doi.org/10.3390/md13063640.
[55] Meng, LingHong, Liu, Yang, Li, XiaoMing, Xu, GangMing, Ji, NaiYun, Wang, BinGui. Citrifelins A and B, Citrinin Adducts with a Tetracyclic Framework from Cocultures of Marine-Derived Isolates of Penicillium citrinum and Beauveria felina. JOURNAL OF NATURAL PRODUCTS[J]. 2015, 第 1 作者78(9): 2301-2305, http://www.irgrid.ac.cn/handle/1471x/1036649.
[56] Zhang, Peng, Meng, LingHong, Mandi, Attila, Li, XiaoMing, Kurtan, Tibor, Wang, BinGui. Structure, absolute configuration, and conformational study of resorcylic acid derivatives and related congeners from the fungus Penicillium brocae. RSC ADVANCES[J]. 2015, 第 2 作者5(50): 39870-39877, http://www.corc.org.cn/handle/1471x/2376512.
[57] Liu, Yang, Li, XiaoMing, Meng, LingHong, Wang, BinGui. Polyketides from the marine mangrove-derived fungus Aspergillus ochraceus MA-15 and their activity against aquatic pathogenic bacteria. PHYTOCHEMISTRY LETTERS[J]. 2015, 第 3 作者12: 232-236, http://www.corc.org.cn/handle/1471x/2376478.
[58] Meng, LingHong, Du, FengYu, Li, XiaoMing, Pedpradab, Patchara, Xu, GangMing, Wang, BinGui. Rubrumazines A-C, Indolediketopiperazines of the Isoechinulin Class from Eurotium rubrum MA-150, a Fungus Obtained from Marine Mangrove-Derived Rhizospheric Soil. JOURNAL OF NATURAL PRODUCTS[J]. 2015, 第 1 作者78(4): 909-913, http://dx.doi.org/10.1021/np5007839.
[59] Zhang, Peng, Meng, LingHong, Mandi, Attila, Li, XiaoMing, Kurtan, Tibor, Wang, BinGui. structure, absolute configuration, and conformational study of resorcylic acid derivatives and related congeners from the fungus Penicillium brocae (vol 5, pg 39870, 2015). RSC ADVANCES. 2015, 第 2 作者5(62): 49904-49904, http://www.corc.org.cn/handle/1471x/2376725.
[60] Meng, LingHong, Li, XiaoMing, Liu, Yang, Wang, BinGui. Polyoxygenated dihydropyrano2,3-cpyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity. CHINESE CHEMICAL LETTERS[J]. 2015, 第 1 作者26(5): 610-612, http://www.corc.org.cn/handle/1471x/2376746.
[61] Meng, LingHong, Li, XiaoMing, Liu, Yang, Wang, BinGui. Penicibilaenes A and B, Sesquiterpenes with a Tricyclo6.3.1.0(1,5)dodecane Skeleton from the Marine Isolate of Penicillium bilaiae MA-267. ORGANIC LETTERS[J]. 2014, 第 1 作者16(23): 6052-6055, http://dx.doi.org/10.1021/ol503046u.
[62] Meng, LingHong, Li, XiaoMing, Lv, CuiTing, Huang, CaiGuo, Wang, BinGui. Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina. JOURNAL OF NATURAL PRODUCTS[J]. 2014, 第 1 作者77(8): 1921-1927, http://dx.doi.org/10.1021/np500382k.
[63] Liu, Yang, Li, XiaoMing, Meng, LingHong, Wang, BinGui. N-Formyllapatin A, a new N-formylspiroquinazoline derivative from the marine-derived fungus Penicillium adametzioides AS-53. PHYTOCHEMISTRY LETTERS[J]. 2014, 第 3 作者10: 145-148, http://dx.doi.org/10.1016/j.phytol.2014.08.018.
[64] Zhang, Peng, Meng, LingHong, Mandi, Attila, Kurtan, Tibor, Li, XiaoMing, Liu, Yang, Li, Xin, Li, ChunShun, Wang, BinGui. Brocaeloids A-C, 4-Oxoquinoline and Indole Alkaloids with C-2 Reversed Prenylation from the Mangrove-Derived Endophytic Fungus Penicillium brocae. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2014, 第 2 作者2014(19): 4029-4036, http://dx.doi.org/10.1002/ejoc.201400067.
[65] Sun, HaoFen, Li, XiaoMing, Meng, LingHong, Cui, ChuanMing, Gao, ShuShan, Li, ChunShun, Wang, BinGui. Two New Secoanthraquinone Derivatives from the Marine-Derived Endophytic Fungus Aspergillus wentii EN-48. HELVETICA CHIMICA ACTA[J]. 2013, 第 3 作者96(3): 458-462, https://www.doi.org/10.1002/hlca.201200201.
[66] Meng, LingHong, Li, XiaoMing, Lv, CuiTing, Li, ChunShun, Xu, GangMing, Huang, CaiGuo, Wang, BinGui. Sulfur-Containing Cytotoxic Curvularin Macrolides from Penicillium sumatrense MA-92, a Fungus Obtained from the Rhizosphere of the Mangrove Lumnitzera racemosa. JOURNAL OF NATURAL PRODUCTS[J]. 2013, 第 1 作者76(11): 2145-2149, http://dx.doi.org/10.1021/np400614f.
科研活动
科研项目
（ 1 ） 中国科学院青年创新促进会会员项 目, 负责人, 中国科学院计划, 2017-01--2020-12
（ 2 ） 汇泉青年学者, 负责人, 研究所自选, 2018-01--2020-12
（ 3 ） 共培养策略提高海洋真菌次级代谢产物的分子多样性和抗菌活性, 负责人, 国家任务, 2019-01--2021-12
（ 4 ） 麦哲伦海山底栖动物内生真菌次级代谢产物多样性及抗水产致病菌活性研究, 负责人, 国家任务, 2020-01--2023-12
（ 5 ） 全球变化背景下信息素在棘皮动物和鱼类中作用过程和机制的比较研究, 参与, 国家任务, 2021-01--2023-12
（ 6 ） 海山底栖动物内生真菌源活性先导化合物的发现与挖掘, 负责人, 地方任务, 2020-07--2023-06
（ 7 ） 海洋植物源真菌共培养增加其代谢产物分子多样性及抗植物病害菌活性研究, 负责人, 国家任务, 2017-01--2019-12
（ 8 ） 海洋真菌来源含硫、含氮杂原子抗肿瘤活性先导化合物的定向分离与鉴定研究, 负责人, 地方任务, 2016-11--2019-06
（ 9 ） 基于海洋真菌-病原真菌共培养策略的抗菌活性代谢产物的发现, 负责人, 国家任务, 2022-01--2025-12
（ 2 ） 汇泉青年学者, 负责人, 研究所自选, 2018-01--2020-12
（ 3 ） 共培养策略提高海洋真菌次级代谢产物的分子多样性和抗菌活性, 负责人, 国家任务, 2019-01--2021-12
（ 4 ） 麦哲伦海山底栖动物内生真菌次级代谢产物多样性及抗水产致病菌活性研究, 负责人, 国家任务, 2020-01--2023-12
（ 5 ） 全球变化背景下信息素在棘皮动物和鱼类中作用过程和机制的比较研究, 参与, 国家任务, 2021-01--2023-12
（ 6 ） 海山底栖动物内生真菌源活性先导化合物的发现与挖掘, 负责人, 地方任务, 2020-07--2023-06
（ 7 ） 海洋植物源真菌共培养增加其代谢产物分子多样性及抗植物病害菌活性研究, 负责人, 国家任务, 2017-01--2019-12
（ 8 ） 海洋真菌来源含硫、含氮杂原子抗肿瘤活性先导化合物的定向分离与鉴定研究, 负责人, 地方任务, 2016-11--2019-06
（ 9 ） 基于海洋真菌-病原真菌共培养策略的抗菌活性代谢产物的发现, 负责人, 国家任务, 2022-01--2025-12
参与会议
（1）海洋真菌中活性次级代谢产物的结构多样性研究 2020年中国药学大会 2020-09-08
（2）海洋真菌中含硫、含氮等天然产物的结构多样性与活性研究 第十四届海洋药物学术年会暨2019国际海洋药物论坛 2019-11-13
（2）海洋真菌中含硫、含氮等天然产物的结构多样性与活性研究 第十四届海洋药物学术年会暨2019国际海洋药物论坛 2019-11-13
指导学生
已指导学生
王莹 硕士研究生 085238-生物工程
现指导学生
英振 硕士研究生 086000-生物与医药
冯星妍 硕士研究生 086000-生物与医药
张澳元 硕士研究生 086000-生物与医药