基本信息

王旭霞 女  武汉物理与数学研究所
电子邮件:wangxuxia@wipm.ac.cn
通信地址:武汉市武昌小洪山西30号
邮政编码:

招生信息

   
招生专业
070208-无线电物理
招生方向
小动物脑疾病的磁共振成像研究

教育背景

2002-09--2008-06 中国科学院武汉物理与数学研究所 博士学位

工作经历

   
工作简历
2008-07--今 中国科学院武汉物理与数学研究所 工作

出版信息

   
发表论文
[1] Xuxia Wang, Fuchun Lin, Yan Kang, Hao Lei. Brain structural plasticity in rats subjected to early binocular enucleation characterized by high resolution anatomical magnetic resonance imaging and diffusion tensor imaging. MAGNETIC RESONANCE LETTERS[J]. 2023, 3(1): 14-21, http://dx.doi.org/10.1016/j.mrl.2022.10.001.
[2] Wang, Xuxia, Li, Ronghui, He, Rui, Fang, Fang. Effects of repeated manganese treatment on proton magnetic resonance spectra of the globus pallidus in rat brain. NMR IN BIOMEDICINE[J]. 2022, 35(1): http://dx.doi.org/10.1002/nbm.4617.
[3] 胡赢丹, 蔡悦, 王旭霞, 刘思婕, 康彦, 雷皓, 林富春. 尼古丁易感的脑结构特征的磁共振成像研究. 波谱学杂志[J]. 2021, 38(3): 345-355, http://lib.cqvip.com/Qikan/Article/Detail?id=7105477469.
[4] Li, Ronghui, Wang, Xuxia, Lin, Fuchun, Song, Tao, Zhu, Xutao, Lei, Hao. Mapping accumulative whole-brain activities during environmental enrichment with manganese-enhanced magnetic resonance imaging. NEUROIMAGE[J]. 2020, 210: http://dx.doi.org/10.1016/j.neuroimage.2020.116588.
[5] Gao, Lifeng, Huang, Mingming, Luo, Xiaowen, Song, Tao, Wang, Xuxia, Wang, Zhe, Zhang, Wei, Chen, Jiangyuan, Lei, Hao. Microstructure abnormity in the optic nerve of type 1 diabetic rats revealed by diffusion tensor imaging study. MAGNETIC RESONANCE IMAGING[J]. 2020, 71: 105-114, http://dx.doi.org/10.1016/j.mri.2020.05.003.
[6] Zhou, Wenchang, Cai, Aoling, Nie, Binbin, Zhang, Wen, Yang, Ting, Zheng, Ning, Manyande, Anne, Wang, Xuxia, Xu, Fuqiang, Tian, Xuebi, Wang, Jie. Investigation of robust visual reaction and functional connectivity in the rat brain induced by rocuronium bromide with functional MRI. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH[J]. 2020, 12(6): 2396-2408, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000548245700005.
[7] AnQi Chen, Zhi Fang, XiaoLu Chen, Shuai Yang, YiFan Zhou, Ling Mao, YuanPeng Xia, HuiJuan Jin, YaNan Li, MingFeng You, XuXia Wang, Hao Lei, QuanWei He, Bo Hu. Microglia-derived TNF-α mediates endothelial necroptosis aggravating blood brain–barrier disruption after ischemic stroke. CELL DEATH AND DISEASE[J]. 2019, 10(7): 1-18, https://doaj.org/article/c466c341dffd4bd5b76ca611536681c2.
[8] Zhou, YiFan, Li, YaNan, Jin, HuiJuan, Wu, JieHong, He, QuanWei, Wang, XuXia, Lei, Hao, Hu, Bo. Sema4D/PlexinB1 inhibition ameliorates blood-brain barrier damage and improves outcome after stroke in rats. FASEB JOURNAL[J]. 2018, 32(4): 2181-2196, http://202.127.146.157/handle/2RYDP1HH/4937.
[9] Li, Shuang, Wang, Xinghua, Yang, Junjie, Lei, Hao, Wang, Xuxia, Xiang, Yi. Metabolic profile of visual cortex in diabetic rats measured with in vivo proton MRS. NMR IN BIOMEDICINE[J]. 2017, 30(11): http://dx.doi.org/10.1002/nbm.3783.
[10] Wu, H, Wang, X, Gao, Y, Lin, F, Song, T, Zou, Y, Xu, L, Lei, H. NMDA RECEPTOR ANTAGONISM BY REPETITIVE MK801 ADMINISTRATION INDUCES SCHIZOPHRENIA-LIKE STRUCTURAL CHANGES IN THE RAT BRAIN AS REVEALED BY VOXEL-BASED MORPHOMETRY AND DIFFUSION TENSOR IMAGING. NEUROSCIENCE[J]. 2016, 322: 221-233, http://dx.doi.org/10.1016/j.neuroscience.2016.02.043.
[11] Feng, Yue, Zhu, Hang, Zhang, Xu, Wang, Xuxia, Xu, Fuqiang, Tang, Huiru, Ye, Chaohui, Liu, Maili. NMR Based Cerebrum Metabonomic Analysis Reveals Simultaneous Interconnected Changes during Chick Embryo Incubation. PLOS ONE[J]. 2015, 10(10): http://ir.wipm.ac.cn/handle/112942/9031.
[12] Wang, Xuxia, Lin, Fuchun, Gao, Yunling, Lei, Hao. Bilateral common carotid artery occlusion induced brain lesions in rats: A longitudinal diffusion tensor imaging study. MAGNETIC RESONANCE IMAGING[J]. 2015, 33(5): 551-558, http://dx.doi.org/10.1016/j.mri.2015.02.010.
[13] Zhang, Run, Fa, Zhiqiang, Liu, Yi, Sun, Haitao, Li, Peng, Li, Shaorui, Wang, Xuxia, Lei, Hao, Jiang, Xiaodan. Dynamic MRI of rat brain following manganese administration through the internal carotid artery. NEUROLOGICAL RESEARCH[J]. 2014, 36(7): 679-686, http://ir.iphy.ac.cn/handle/311004/59397.
[14] Xiao, Yan, Xue, Rong, You, Tianyan, Li, Xiaojing, Pei, Fengkui, Wang, Xuxia, Lei, Hao. Gadolinium-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugate of arabinogalactan as a potential liver-targeting magnetic resonance imaging contrast agent. CARBOHYDRATE RESEARCH[J]. 2014, 395(33): 9-14, http://dx.doi.org/10.1016/j.carres.2014.05.022.
[15] Li, Jianfeng, Huang, Shixian, Shao, Kun, Liu, Yang, An, Sai, Kuang, Yuyang, Guo, Yubo, Ma, Haojun, Wang, Xuxia, Jiang, Chen. A choline derivate-modified nanoprobe for glioma diagnosis using MRI. SCIENTIFIC REPORTS[J]. 2013, 3: http://www.irgrid.ac.cn/handle/1471x/960781.
[16] He, Rui, Xing, Gengmei, Wang, Xuxia, Jiao, Yanhua, Zhao, Hong, Yuan, Hui, Wang, Shukuan, Dong, Jinquan, Lei, Hao. Synthesis and Evaluation of Bingel-Hirsch Multiadducts of Paramagnetic Gadofullerene as Potential Magnetic Resonance Imaging Contrast Agents. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2013, 13(2): 1549-1554, http://ir.ihep.ac.cn/handle/311005/224150.
[17] Hou, Yi, Qiao, Ruirui, Fang, Fang, Wang, Xuxia, Dong, Chengyan, Liu, Kan, Liu, Chunyan, Liu, Zhaofei, Lei, Hao, Wang, Fan, Gao, Mingyuan. NaGdF4 Nanoparticle-Based Molecular Probes for Magnetic Resonance Imaging of Intraperitoneal Tumor Xenografts in Vivo. ACS NANO[J]. 2013, 7(1): 330-338, http://ir.wipm.ac.cn/handle/112942/949.
[18] 邓尚友, 方可, 王旭霞, 谭萍. 自触发心脏磁共振成像. 中国医学影像技术[J]. 2012, 28(1): 164-, http://lib.cqvip.com/Qikan/Article/Detail?id=40570527.
[19] 林富春, 王旭霞, 赵前程, 雷皓. 小动物高分辨扩散磁共振成像数据分析方法. 生物化学与生物物理进展[J]. 2012, 39(6): 513-, http://lib.cqvip.com/Qikan/Article/Detail?id=42213446.
[20] Yan, Huihui, Wang, Lu, Wang, Jiyao, Weng, Xiaofu, Lei, Hao, Wang, Xuxia, Jiang, Lu, Zhu, Jianhua, Lu, Weiyue, Wei, Xunbin, Li, Cong. Two-Order Targeted Brain Tumor Imaging by Using an Optical/Paramagnetic Nanoprobe across the Blood Brain Barrier. ACS NANO[J]. 2012, 6(1): 410-420, http://ir.wipm.ac.cn/handle/112942/1594.
[21] Mao, Xian, Li, Ning, Mao, Jiezhen, Li, Qiurong, Xiao, Nan, Jiang, Bin, Jiang, Ling, Wang, Xuxia, Liu, Maili. Fast detection of choline-containing metabolites in liver using 2D H-1-N-14 three-bond correlation (HN3BC) spectroscopy. JOURNAL OF MAGNETIC RESONANCE[J]. 2012, 214: 352-359, http://ir.wipm.ac.cn/handle/112942/1688.
[22] Han, Liang, Li, Jianfeng, Huang, Shixian, Huang, Rongqin, Liu, Shuhuan, Hu, Xing, Yi, Peiwei, Shan, Dai, Wang, Xuxia, Lei, Hao, Jiang, Chen. Peptide-conjugated polyamidoamine dendrimer as a nanoscale tumor-targeted T1 magnetic resonance imaging contrast agent. BIOMATERIALS[J]. 2011, 32(11): 2989-2998, http://dx.doi.org/10.1016/j.biomaterials.2011.01.005.
[23] Li,S, Huang,MM, Wang,XH, Wang,XX, Chen,F, Lei,H, Jiang,FG. Retinal Metabolic Changes in an Experimental Model of Optic Nerve Transection by Ex Vivo (1)H Magnetic Resonance Spectroscopy. NEUROCHEMICAL RESEARCH[J]. 2011, 36(12): 2427-2433, http://ir.wipm.ac.cn/handle/112942/1909.
[24] Xu, Wei, Zhan, Yanqiang, Huang, Wei, Wang, Xuxia, Zhang, Sumin, Lei, Hao. Reduction of Hippocampal N-Acetyl Aspartate Level in Aged APP(Swe)/PS1(dE9) Transgenic Mice Is Associated With Degeneration of CA3 Pyramidal Neurons. JOURNAL OF NEUROSCIENCE RESEARCH[J]. 2010, 88(14): 3155-3160, http://dx.doi.org/10.1002/jnr.22479.
[25] Meng, Huan, Xing, Gengmei, Sun, Baoyun, Zhao, Feng, Lei, Hao, Li, Wei, Song, Yan, Chen, Zhen, Yuan, Hui, Wang, Xuxia, Long, Jing, Chen, Chunying, Liang, Xingjie, Zhang, Ning, Chai, Zhifang, Zhao, Yuliang. Potent Angiogenesis Inhibition by the Particulate Form of Fullerene Derivatives. ACS NANO[J]. 2010, 4(5): 2773-2783, http://ir.ihep.ac.cn/handle/311005/239820.
[26] Zhang, Zhi, He, Rui, Yan, Kun, Guo, Qianni, Lu, Yunguo, Wang, Xuxia, Lei, Hao, Li, Zaoying. Synthesis and in vitro and in vivo evaluation of manganese(III) porphyrin-dextran as a novel MRI contrast agent. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS[J]. 2009, 19(23): 6675-6678, http://dx.doi.org/10.1016/j.bmcl.2009.10.003.
[27] Li, Yingxia, Fang, Fang, Wang, Xuxia, Lei, Hao. Neuronal projections from ventral tegmental area to forebrain structures in rat studied by manganese-enhanced magnetic resonance imaging. MAGNETIC RESONANCE IMAGING[J]. 2009, 27(3): 293-299, http://dx.doi.org/10.1016/j.mri.2008.07.011.
[28] Li, Weisheng, Li, Zhongfeng, Jing, Fengying, Deng, Yuefeng, Wei, Lai, Liao, Peiqiu, Yang, Xiangguang, Li, Xiaojing, Pei, Fengkui, Wang, Xuxia, Lei, Hao. Synthesis and evaluation of Gd-DTPA-labeled arabinogalactans as potential MRI contrast agents. CARBOHYDRATE RESEARCH[J]. 2008, 343(4): 685-694, http://dx.doi.org/10.1016/j.carres.2008.01.008.
[29] He, Rui, Wang, Xuxia, Fang, Ke, Liu, Nianqing, Zhang, Zhiyong, Huang, Yuying, He, Wei, Lei, Hao. Elemental distributions in rat olfactory bulbs after exposure to MnCl2 measured by synchrotron radiation X-ray fluorescence. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY[J]. 2007, 272(3): 589-593, http://ir.ihep.ac.cn/handle/311005/238044.
[30] Li, Zhongfeng, Li, Weisheng, Li, Xiaojing, Pei, Fengkui, Wang, Xuxia, Lei, Hao. Mn(II)-monosubstituted polyoxometalates as candidates for contrast agents in magnetic resonance imaging. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2007, 101(7): 1036-1042, http://dx.doi.org/10.1016/j.jinorgbio.2007.04.003.
[31] Wang, Xuxia, Qian, Junchao, He, Rui, Wei, Li, Liu, Nianqing, Zhang, Zhiyong, Huang, Yuying, Lei, Hao. Delayed changes in T-1-weighted signal intensity in a rat model of 15-minute transient focal ischemia studied by magnetic resonance imaging/spectroscopy and synchrotron radiation X-ray fluorescence. MAGNETIC RESONANCE IN MEDICINE[J]. 2006, 56(3): 474-480, http://ir.wipm.ac.cn/handle/112942/4589.
[32] 王旭霞, 李英霞, 方芳, 方可, 雷皓. 外源性锰在大鼠脑内选择性沉积的磁共振成像研究. 中国医学影像技术[J]. 2006, 22(10): 1538-, http://ir.wipm.ac.cn/handle/112942/18751, http://www.irgrid.ac.cn/handle/1471x/6858344, http://ir.wipm.ac.cn/handle/112942/18752.
[33] Xuxia Wang, Fuchun Lin, Yan Kang, Hao Lei. Brain structural plasticity in rats subjected to early binocular enucleation characterized by high resolution anatomical magnetic resonance imaging and diffusion tensor imaging. MAGNETIC RESONANCE LETTERS. http://dx.doi.org/10.1016/j.mrl.2022.10.001.

科研活动

   
科研项目
(1) 基于“铁蛋白-髓鞘-轴突”机制的多模态MRI对阿尔茨海默病的早期预测研究,参与,国家级,2012-01--2015-12
(2) 视觉剥夺引起大鼠脑结构可塑性改变的多模态磁共振成像研究,主持,国家级,2011-01--2013-12
参与会议
(1) 锰中毒引起大鼠苍白球代谢紊乱的磁共振波谱研究,第15届全国波谱学学术会议,2008-10,王旭霞