085238-生物工程

基因组学
数量遗传学

2005-09--2009-01 中国农业大学 博士
1998-09--2005-07 山西农业大学 学士、硕士

   

2009-09--2012-01 美国马里兰大学；美国农业部动物与自然资源系 博士后
2006-10--2008-03 丹麦奥胡斯大学遗传与生物技术系 访问学者

   

（1） 校长奖学金，研究所（学校）级，2004

   

[1] Yali Hou, Zhao, Shilei, liu qi, zhang xiaolong, Yongbiao Xue, Hua Chen. Ongoing positive selection drives the evolution of SARS-CoV-2 genomes. Genomics, Proteomics & Bioinformatics[J]. 2022, [2] Zhao, Shilei, Yali Hou, Hua Chen, Xue, Yongbiao. Pinpointing the animal origins of SARS-CoV-2: a genomic approach. Journal of Genetics and Genomics[J]. 2022, [3] Chen, Xia, Bai, Xue, Liu, Huagui, Zhao, Binbin, Yan, Zhixun, Hou, Yali, Chu, Qin. Population Genomic Sequencing Delineates Global Landscape of Copy Number Variations that Drive Domestication and Breed Formation of in Chicken. FRONTIERS IN GENETICS[J]. 2022, 13: http://dx.doi.org/10.3389/fgene.2022.830393.
[4] Sun, Dongxiao, Hou, Yali, Xie, Yan, Yang, Shaohua, Han, Bo, Shi, Lijun, Bai, Xue, Liang, Ruobing, Dong, Tian, Zhang, Shengli, Zhang, Qin. EEF1D facilitates milk lipid synthesis by regulation of PI3K-Akt signaling in mammals. FASEB JOURNAL[J]. 2021, 35(5): http://dx.doi.org/10.1096/fj.202000682RR.
[5] Li, Chunyan, Olave, Melisa, Hou, Yali, Qin, Geng, Schneider, Ralf F, Gao, Zexia, Tu, Xiaolong, Wang, Xin, Qi, Furong, Nater, Alexander, Kautt, Andreas F, Wan, Shiming, Zhang, Yanhong, Liu, Yali, Zhang, Huixian, Zhang, Bo, Zhang, Hao, Qu, Meng, Liu, Shuaishuai, Chen, Zeyu, Zhong, Jia, Zhang, He, Meng, Lingfeng, Wang, Kai, Yin, Jianping, Huang, Liangmin, Venkatesh, Byrappa, Meyer, Axel, Lu, Xuemei, Lin, Qiang. Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution. NATURE COMMUNICATIONS[J]. 2021, 12(1): https://doaj.org/article/4c6a58d53f7140b1ae6ebc48c1b1ee50.
[6] Tao Li, Jialin Liu, Jing Feng, Zhenzhen Liu, Sixue Liu, Minjie Zhang, Yuezheng Zhang, Yali Hou, Dafei Wu, Chunyan Li, Yongbin Chen, Hua Chen, Xuemei Lu. Variation in the life history strategy underlies functional diversity of tumors. NATIONAL SCIENCE REVIEW. 2020, 8(2): [7] Hou Yali. Genomic Analysis Revealed a Convergent Evolution of LINE-1 inCoat Color: A Case Study in Water Buffaloes (Bubalus bubalis). Mol. Biol. Evol.. 2020, [8] Hou, Yali, Qi, Furong, Bai, Xue, Ren, Tong, Shen, Xu, Chu, Qin, Zhang, Xiquan, Lu, Xuemei. Genome-wide analysis reveals molecular convergence underlying domestication in 7 bird and mammals. BMC GENOMICS[J]. 2020, 21(1): https://doaj.org/article/314610e6c7de4c4bb6f6a174d798387d.
[9] Qi, Furong, Yang, Airong, Ambreen, Sadaf, Bai, Xue, Hou, Yali, Lu, Xuemei. Birth and death of Mx genes and the presence/absence of genes regulating Mx transcription are correlated with the diversity of anti-pathogenicity in vertebrate species. MOLECULAR GENETICS AND GENOMICS[J]. 2019, 294(1): 121-133, https://www.webofscience.com/wos/woscc/full-record/WOS:000457456800011.
[10] Fan, Hongying, Hou, Yali, Sahana, Goutam, Gao, Hongding, Zhu, Caiye, Du, Lixin, Zhao, Fuping, Wang, Lixian. A Transcriptomic Study of the Tail Fat Deposition in Two Types of Hulun Buir Sheep According to Tail Size and Sex. ANIMALS[J]. 2019, 9(9): http://dx.doi.org/10.3390/ani9090655.
[11] Li, Chunyan, Hou, Yali, Xu, Jin, Zhang, Aiqun, Liu, Zhenzhen, Qi, Furong, Yang, Zuyu, Chen, Ke, Liu, Sixue, Huang, Huanwei, Wang, Qianfei, Dong, Jiahong, Wu, ChungI, Lu, Xuemei. A Direct Test of Selection in Cell Populations Using the Diversity in Gene Expression within Tumors. MOLECULAR BIOLOGY AND EVOLUTION[J]. 2017, 34(7): 1730-1742, https://www.webofscience.com/wos/woscc/full-record/WOS:000402754400016.
[12] Gao, Yahui, Jiang, Jianping, Yang, Shaohua, Hou, Yali, Liu, George E, Zhang, Shengli, Zhang, Qin, Sun, Dongxiao. CNV discovery for milk composition traits in dairy cattle using whole genome resequencing. BMC GENOMICS[J]. 2017, 18(1): http://dx.doi.org/10.1186/s12864-017-3636-3.
[13] Xu, Lingyang, Hou, Yali, Bickhart, Derek M, Zhou, Yang, Hay, El Hamidi Abdel, Song, Jiuzhou, Sonstegard, Tad S, Van Tassell, Curtis P, Liu, George E. Population-genetic properties of differentiated copy number variations in cattle. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000372609400001.
[14] Fang, Lingzhao, Hou, Yali, An, Jing, Li, Bingjie, Song, Minyan, Wang, Xiao, Sorensen, Peter, Dong, Yichun, Liu, Chao, Wang, Yachun, Zhu, Huabin, Zhang, Shengli, Yu, Ying. Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to Staphylococcus aureus. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY[J]. 2016, 6: http://dx.doi.org/10.3389/fcimb.2016.00193.
[15] Wang, Kaile, Ma, Qin, Jiang, Lan, Lai, Shujuan, Lu, Xuemei, Hou, Yali, Wu, ChungI, Ruan, Jue. Ultra-precise detection of mutations by droplet-based amplification of circularized DNA. BMC GENOMICS[J]. 2016, 17(1): http://www.corc.org.cn/handle/1471x/2374305.
[16] Kaile Wang, Qin Ma, Lan Jiang, Shujuan Lai, Xuemei Lu, Yali Hou, Chung-I Wu, Jue Ruan. Erratum to: ‘Ultra-precise detection of mutations by droplet-based amplification of circularized DNA’. BMC GENOMICS. 2016, 17(1): http://www.corc.org.cn/handle/1471x/2374306.
[17] Cui, Xiaogang, Hou, Yali, Yang, Shaohua, Xie, Yan, Zhang, Shengli, Zhang, Yuan, Zhang, Qin, Lu, Xuemei, Liu, George E, Sun, Dongxiao. Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing. BMC GENOMICS[J]. 2014, 15(1): 226-226, http://dx.doi.org/10.1186/1471-2164-15-226.
[18] Xu, Lingyang, Hon, Yali, Bickhart, Derek M, Song, Jiuzhou, Van Tassell, Curtis P, Sonstegard, Tad S, Liu, George E. A genome-wide survey reveals a deletion polymorphism associated with resistance to gastrointestinal nematodes in Angus cattle. FUNCTIONAL & INTEGRATIVE GENOMICS[J]. 2014, 14(2): 333-339, https://www.webofscience.com/wos/woscc/full-record/WOS:000338197800006.
[19] Xu, Lingyang, Cole, John B, Bickhart, Derek M, Hou, Yali, Song, Jiuzhou, VanRaden, Paul M, Sonstegard, Tad S, Van Tassell, Curtis P, Liu, George E. Genome wide CNV analysis reveals additional variants associated with milk production traits in Holsteins. BMC GENOMICS[J]. 2014, 15(1): http://dx.doi.org/10.1186/1471-2164-15-683.
[20] Yali Hou, Yachun Wang, Xuemei Lu, Xu Zhang, Qian Zhao, Rory J Todhunter, Zhiwu Zhang. Correction: Monitoring Hip and Elbow Dysplasia Achieved Modest Genetic Improvement of 74 Dog Breeds over 40 Years in USA. PLOS ONE[J]. 2013, 8(10): https://doaj.org/article/6574da6a9e09403e8ec52e0561a1b487.
[21] Hou Yali. Analyses of copy number variations in Holstein cows identify potential mechanisms contributing to differences in residual feed intake. Functional and Integrative Genomics. 2012, [22] Hou, Yali, Bickhart, Derek M, Hvinden, Miranda L, Li, Congjun, Song, Jiuzhou, Boichard, Didier A, Fritz, Sebastien, Eggen, Andre, DeNise, Sue, Wiggans, George R, Sonstegard, Tad S, Van Tassell, Curtis P, Liu, George E. Fine mapping of copy number variations on two cattle genome assemblies using high density SNP array. BMC GENOMICS[J]. 2012, 13(1): 376-376, http://dx.doi.org/10.1186/1471-2164-13-376.
[23] Hou, Yali, Liu, George E, Bickhart, Derek M, Matukumalli, Lakshmi K, Li, Congjun, Song, Jiuzhou, Gasbarre, Louis C, Van Tassell, Curtis P, Sonstegard, Tad S. Genomic regions showing copy number variations associate with resistance or susceptibility to gastrointestinal nematodes in Angus cattle. FUNCTIONAL & INTEGRATIVE GENOMICS[J]. 2012, 12(1): 81-92, https://www.webofscience.com/wos/woscc/full-record/WOS:000301834100007.
[24] Bickhart, Derek M, Hou, Yali, Schroeder, Steven G, Alkan, Can, Cardone, Maria Francesca, Matukumalli, Lakshmi K, Song, Jiuzhou, Schnabe, Robert D, Ventura, Mario, Taylor, Jeremy F, Garcia, Jose Fernando, Van Tasse, Curtis P, Sonstegard, Tad S, Eichler, Evan E, Liu, George E. Copy number variation of individual cattle genomes using next-generation sequencing. GENOME RESEARCH[J]. 2012, 22(4): 778-790, https://www.webofscience.com/wos/woscc/full-record/WOS:000302203800018.
[25] Zhongde Wang, Yoshimi Kuroiwa, James M Robl, Yali Hou, George E Liu. Assessment of genome integrity with array CGH in cattle transgenic cell lines produced by homologous recombination and somatic cell cloning. GENOME INTEGRITY[J]. 2011, 2(1): http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706307744810ZK.
[26] Hou, Yali, Liu, George E, Bickhart, Derek M, Cardone, Maria Francesca, Wang, Kai, Kim, Euisoo, Matukumalli, Lakshmi K, Ventura, Mario, Song, Jiuzhou, VanRaden, Paul M, Sonstegard, Tad S, Van Tassell, Curt P. Genomic characteristics of cattle copy number variations. BMC GENOMICS[J]. 2011, 12(1): 127-127, https://doaj.org/article/902ad0fe7d77468a80bee2bf9eaa8c6f.
[27] Liu, George E, Hou, Yali, Zhu, Bin, Cardone, Maria Francesca, Jiang, Lu, Cellamare, Angelo, Mitra, Apratim, Alexander, Leeson J, Coutinho, Luiz L, DellAquila, Maria Elena, Gasbarre, Lou C, Lacalandra, Gianni, Li, Robert W, Matukumalli, Lakshmi K, Nonneman, Dan, Regitano, Luciana C de A, Smith, Tim P L, Song, Jiuzhou, Sonstegard, Tad S, Van Tassell, Curt P, Ventura, Mario, Eichler, Evan E, McDaneld, Tara G, Keele, John W. Analysis of copy number variations among diverse cattle breeds. GENOME RESEARCH[J]. 2010, 20(5): 693-703, https://www.webofscience.com/wos/woscc/full-record/WOS:000277244800015.
[28] Li, Robert W, Hou, Yali, Li, Congjun, Gasbarre, Louis C. Localized complement activation in the development of protective immunity against Ostertagia ostertagi infections in cattle. VETERINARY PARASITOLOGY[J]. 2010, 174(3-4): 247-256, http://dx.doi.org/10.1016/j.vetpar.2010.08.037.
[29] Hou, Yali, Wang, Yachun, Lust, George, Zhu, Lan, Zhang, Zhiwu, Todhunter, Rory J. Retrospective Analysis for Genetic Improvement of Hip Joints of Cohort Labrador Retrievers in the United States: 1970-2007. PLOS ONE[J]. 2010, 5(2): https://doaj.org/article/1af293b4e1154b369ca3fd141dee0858.
[30] Hou Yali. Genetic Analysis of Days from Calving to First Insemination and Days Open in Danish Holstein Using Different Models and Censoring Scenarios. Dairy Science. 2009,