071008-发育生物学

再生医学、发育生物学

2004-09--2009-06   中国农业大学   博士
2000-09--2004-06   河北大学   学士

   

2013-01~现在, 中国科学院动物研究所, 副研究员
2009-07~2012-12,中国科学院动物研究所, 助理研究员
2004-09~2009-06,中国农业大学, 博士
2000-09~2004-06,河北大学, 学士

   

（1） Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics, Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics, CELL RESEARCH, 2022, 第 7 作者
（2） A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 第 9 作者
（3） Smarca5-mediated epigenetic programming facilitates fetal HSPC development in vertebrates, BLOOD, 2021, 第 3 作者
（4） De novo generation of macrophage from placenta-derived hemogenic endothelium, DEVELOPMENTAL CELL, 2021, 第 8 作者
（5） Generation of foxn1/Casper Mutant Zebrafish for Allograft and Xenograft of Normal and Malignant Cells, STEM CELL REPORTS, 2020, 第 2 作者
（6） Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling, PLOS BIOLOGY, 2020, 第 6 作者
（7） Primary cilia regulate hematopoietic stem and progenitor cell specification through Notch signaling in zebrafish, NATURE COMMUNICATIONS, 2019, 第 5 作者
（8） 胚胎期造血干细胞发育的分子调控, Molecular Regulation of Hematopoietic Stem Cell during Embryogenesis, 中国细胞生物学学报, 2017, 第 2 作者
（9） Essential Role for SUN5 in Anchoring Sperm Head to the Tail, ELIFE, 2017, 第 9 作者
（10） The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b, DEVELOPMENTAL CELL, 2017, 第 5 作者
（11） m(6)A modulates haematopoietic stem and progenitor cell specification, NATURE, 2017, 第 6 作者
（12） Epigenetic Regulation of Left-Right Asymmetry by DNA Methylation, EMBO JOURNAL, 2017, 第 4 作者
（13） The rising zebrafish research in China:Meeting report of the 3rd Chinese Zebrafish Principal Investigator Meeting & the Inaugural Meeting of China Zebrafish Society, 遗传学报(英文版), 2016, 第 1 作者
（14） Irf4 Regulates the Choice between T Lymphoid-Primed Progenitor and Myeloid Lineage Fates during Embryogenesis, DEVELOPMENTAL CELL, 2015, 第 3 作者
（15） Genome Editing and Its Applications in Model Organisms, Genome Editing and Its Applications in Model Organisms, GENOMICS PROTEOMICS & BIOINFORMATICS, 2015, 第 1 作者
（16） G protein-coupled receptor 183 facilitates endothelial-to-hematopoietic transition via Notch1 inhibition., CELL RESEARCH, 2015, 第 7 作者
（17） Inflammatory Signaling Regulates Hematopoietic Stem and Progenitor Cell Emergence in Vertebrates, BLOOD, 2015, 第 5 作者
（18） Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish., BLOOD, 2014, 第 2 作者
（19） Regulatory mechanisms of thymus and T cell development, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2013, 第 1 作者
（20） Foxn1 maintains thymic epithelial cells to support T-cell development via mcm2 in zebrafish, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 第 1 作者
（21） 烟草转酮醇酶基因（NtTK）的克隆与表达, Cloning and Expression of Transketolase Gene (NtTK)in Tobacco, 河南农业大学学报, 2008, 第 2 作者

   

（ 1 ） 血液发育相关转录因子突变体系统研制, 参与, 国家任务, 2019-09--2024-08
（ 2 ） Foxn1及其下游基因调控斑马鱼胸腺和T细胞发育分子机制的研究, 负责人, 国家任务, 2014-01--2017-12
（ 3 ） Foxn1调控斑马鱼胸腺及T细胞发育分子机制的初步研究, 负责人, 国家任务, 2011-01--2013-12