Wenjun Tang
Research Professor
State Key Laboratory of Bio-Organic & Natural Products Chemistry
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
345 Ling Ling Road, Shanghai 200032
Tel: (+0086)-21-54925515
E-mail: tangwenjun@sioc.ac.cn
Group website:http://wenjuntang.sioc.ac.cn
Research Areas
1) Design and development of novel, efficient, and practical chiral catalytic reactions;
2) Total synthesis of complex and biologically active natural products;
3) Green synthesis of active pharmaceutical drugs or agrochemicals.
Education
1995 B.Eng., East China University of Sciences and Technology (supervisor: Prof. Guohou Cheng)
1998 M.Sc., Shanghai Institute of Organic Chemistry, CAS (supervisor: Prof. Dawei Ma)
2003 Ph.D., Department of Chemistry, The Pennsylvania State University (supervisor: Prof. Xumu Zhang)
Experience
2003 Postdoctoral fellow, The Scripps Research Institute (supervisor: Prof. KC Nicolaou)
2005 Senior scientist, Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc.
2009 Principal scientist, Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc.
2011 Research professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Work Experience
2003 Postdoctoral fellow, The Scripps Research Institute (supervisor: Prof. KC Nicolaou)
2005 Senior scientist, Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc.
2009 Principal scientist, Chemical Development, Boehringer Ingelheim Pharmaceuticals Inc.
2011 Research professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Teaching Experience
Advanced Organic Chemistry
Honors & Distinctions
2012 National “Thousand Talents” Youth program
2012 Thieme Chemistry Journal Award
2015 Asian Core Lectureship Award
2015 National Homogenous Catalysis Youth Award
2017 The National Science Fund for Distinguished Young Scholars
Publications
D. Chen, G. Xu, Q. Zhou, L. -W. Chung, W. Tang* Practical and Asymmetric Reductive Coupling of Isoquinolines Templated by Chiral Diborons J. Am. Chem. Soc. 2017, 139, 9767-9770.
G. Zhao, G. Xu, Q. Chao, W. Tang* Efficient Enantioselective Syntheses of (+)-Dalesconol A & B J. Am. Chem. Soc., 2017, 139, 3360-3363.
C. Li, Y. Zhang, Q. Sun, T. Gu, H. Peng, W. Tang* Transition-Metal-Free Stereospecific Cross-Coupling with Alkenylboronic Acids as Nucleophiles J. Am. Chem. Soc. 2016, 138, 10774-10777.
N. Hu, K. Li, Z. Wang, W. Tang* Synthesis of Chiral 1,4-Benzodioxanes and Chromans by Enantioselective Palladium-Catalyzed Alkene Aryloxyarylation Angew. Chem., Int. Ed. 2016, 55, 5044-5048
L. Huang, J. Zhu, G. Jiao, Z. Wang, X. Yu, W.-P. Deng,* W. Tang* Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Ketones: Efficient Synthesis of Escitalopram Angew. Chem., Int. Ed. 2016, 55, 4527-4531.
N. Hu, G. Zhao, Y. Zhang, X. Liu, G. Li, W. Tang* Synthesis of Chiral α-Amino Tertiary Boronic Esters by Enantioselective Hydroboration of α-Arylenamides J. Am. Chem. Soc. 2015, 137, 6746-6749.
C. Li, T. Chen, G. Xiao, B. Li, W. Tang* Efficient Syntheses of Sterically Hindered Acyclic Secondary Alkyl Arenes by Suzuki-Miyaura Cross-Couplings Angew. Chem., Int. Ed. 2015, 54, 3792-3796.
K. Du, P. Guo, Y. Chen, Z. Cao, W. Tang* Enantioselective Palladium-Catalyzed Dearomative Cyclization for Efficient Synthesis of Terpenes and Steroids Angew. Chem., Int. Ed. 2015, 54, 3033-3037.
W. Fu, M. Nie, A. Wang, W. Tang* Highly Enantioselective Nickel-Catalyzed Intramolecular Reductive Cyclization of Alkynone Angew. Chem., Int. Ed. 2015, 54, 2520-2524.
G. Xu, W. Fu, G. Liu, C. H. Senanayake, W. Tang* Efficient Syntheses of Korupensamine A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions J. Am. Chem. Soc. 2014, 136, 570−573.
G. Liu, X. Liu, Z. Cai, G. Jiao, G. Xu, W. Tang* Design of Phosphorus Ligands with Deep Chiral Pockets: Practical Synthesis fo Chiral β-Arylamines by Asymmetric Hydrogenation Angew. Chem., Int. Ed. 2013, 52, 4235-4238
Research Interests
Design and development of novel, efficient, and practical chiral catalytic reactions
Total synthesis of complex and biologically active natural products
Development of efficient, economical, and green chemical processes for pharmaceutically important molecules
Students
已指导学生
赵庆 硕士研究生 070303-有机化学
郭盼 硕士研究生 085216-化学工程
徐广庆 博士研究生 070303-有机化学
杜康 博士研究生 070303-有机化学
胡乃夫 博士研究生 070303-有机化学
陈栋萍 硕士研究生 070303-有机化学
杨心童 硕士研究生 070303-有机化学
李承喜 博士研究生 070303-有机化学
付文振 博士研究生 070303-有机化学
李博文 博士研究生 070303-有机化学
聂明 博士研究生 070303-有机化学
柏珩 硕士研究生 085216-化学工程
陈远 博士研究生 070303-有机化学
穆星烨 博士研究生 070303-有机化学
李凯迪 硕士研究生 070303-有机化学
田端帅 博士研究生 070303-有机化学
钱超 博士研究生 070303-有机化学
现指导学生
吴婷 博士研究生 070303-有机化学
周明康 博士研究生 070303-有机化学
顾威 硕士研究生 085216-化学工程
柏珩 博士研究生 070303-有机化学
万枫 博士研究生 070303-有机化学
唐自强 硕士研究生 070303-有机化学
林尧东 硕士研究生 070303-有机化学
赵帝 硕士研究生 085216-化学工程
董文锋 博士研究生 070303-有机化学
黄建勋 硕士研究生 070303-有机化学
朱雨欣 硕士研究生 070303-有机化学
常钦仁 硕士研究生 086000-生物与医药
付鑫鹏 硕士研究生 086000-生物与医药
高犇 硕士研究生 085600-材料与化工
贺东阳 硕士研究生 086000-生物与医药
温韬 博士研究生 070303-有机化学
田威 博士研究生 070303-有机化学
唐叶华 硕士研究生 070303-有机化学