病毒纳米生物学

微生物学

   

博士

博士

2008-2012，中国科学院高能物理研究所

2012-至今， 中国科学院武汉病毒研究所

   

[1] 崔宗强, 张晓玮, 李炜, 张先恩. 一种受microRNA调控的重组溶瘤肠道病毒71型及应用. CN: CN111117973A, 2020-05-08.

[2] 崔宗强, 张晓玮, 李炜, 王汉中. 肠道病毒71型在制备溶瘤药物中的应用. CN: CN111110706A, 2020-05-08.

[3] 崔宗强, 印文, 李炜, 张先恩, 李芹, 刘霁. 一种抑制肌动蛋白重组的多肽及应用. CN: CN110194793A, 2019-09-03.

[4] 崔宗强, 陈明海, 李炜, 张先恩. 一种基于荧光蛋白Venus的三片段荧光互补系统及应用. CN: CN109385450A, 2019-02-26.

[5] 崔宗强, 张先恩, 陈明海, 张治平, 李炜. 一种基于荧光蛋白iRFP的双分子荧光片段互补系统及应用. CN: CN105624178A, 2016-06-01.

   

[1] 武伟红, 李炜, 张先恩, 崔宗强. 合成生物学与荧光成像技术. 合成生物学[J]. 2022, 3(2): 369-384, http://lib.cqvip.com/Qikan/Article/Detail?id=7107125374.
[2] Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, JIawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui. Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement. FRONTIERS IN IMMUNOLOGY[J]. 2022, 13: 905431-, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9124840/.
[3] Li, Wei, Liu, Ji, Liu, Yuanyuan, Li, Qin, Yin, Wen, Wanderi, Kevin K, Zhang, Xiaowei, Zhang, Zhiping, Zhang, XianEn, Cui, Zongqiang. HIV-1 Uses Dynamic Podosomes for Entry into Macrophages. JOURNAL OF VIROLOGY[J]. 2021, 95(10): https://www.webofscience.com/wos/woscc/full-record/WOS:000647441000001.
[4] 崔宗强, 李炜, 张先恩. 纳米生物传感研究进展. 中国科学:生命科学[J]. 2020, 50(7): 755-765, https://www.sciengine.com/doi/10.1360/SSV-2019-0300.
[5] Yin, Wen, Li, Wei, Li, Qin, Liu, Yuanyuan, Liu, Ji, Ren, Min, Ma, Yingxin, Zhang, Zhiping, Zhang, Xiaowei, Wu, Yuntao, Jiang, Shibo, Zhang, XianEn, Cui, Zongqiang. Real-time imaging of individual virion-triggered cortical actin dynamics for human immunodeficiency virus entry into resting CD4 T cells. NANOSCALE[J]. 2020, 12(1): 115-129, https://www.webofscience.com/wos/woscc/full-record/WOS:000504106900038.
[6] Zhang, Xiaowei, Wang, Hanzhong, Sun, Yuhan, Qi, Mi, Li, Wei, Zhang, Zhiping, Zhang, XianEn, Cui, Zongqiang. Enterovirus A71 Oncolysis of Malignant Gliomas. MOLECULAR THERAPY[J]. 2020, 28(6): 1533-1546, http://dx.doi.org/10.1016/j.ymthe.2020.04.005.
[7] Hu, Meng, Wang, Fei, Li, Wei, Zhang, Xiaowei, Zhang, Zhiping, Zhang, XianEn, Cui, Zongqiang. Ebola Virus Uptake into Polarized Cells from the Apical Surface. VIRUSES-BASEL[J]. 2019, 11(12): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000506894800052.
[8] Yuan, Jing, Chen, Chen, Cui, Jinghua, Lu, Jing, Yan, Chao, Wei, Xiao, Zhao, Xiangna, Li, NanNan, Li, Shaoli, Xue, Guanhua, Cheng, Weiwei, Li, Boxing, Li, Huan, Lin, Weishi, Tian, Changyu, Zhao, Jiangtao, Han, Juqiang, An, Daizhi, Zhang, Qiong, Wei, Hong, Zheng, Minghua, Ma, Xuejun, Li, Wei, Chen, Xiao, Zhang, Zheng, Zeng, Hui, Ying, Sun, Wu, JianXin, Yang, Ruifu, Liu, Di. Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae. CELL METABOLISM[J]. 2019, 30(4): 675-+, http://dx.doi.org/10.1016/j.cmet.2019.08.018.
[9] Li Wei. Real-time imaging of individual virion-triggered cortical actin dynamics for human immunodeficiency virus entry into resting CD4 T cells. Nanaoscale. 2019, [10] Meng Hu, Fei Wang, Wei Li, Xiaowei Zhang, Zhiping Zhang, XianEn Zhang, Zongqiang Cui. Ebola Virus Uptake into Polarized Cells from the Apical Surface. VIRUSES. 2019, 11(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949903/.
[11] Qin, Chong, Li, Wei, Li, Qin, Yin, Wen, Zhang, Xiaowei, Zhang, Zhiping, Zhang, XianEn, Cui, Zongqiang. Real-time dissection of dynamic uncoating of individual influenza viruses. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019, 116(7): 2577-2582, http://www.corc.org.cn/handle/1471x/2373194.
[12] Yingxin Ma, Zhike He, Tianwei Tan, Wei Li, Zhiping Zhang, Shuang Song, Xiaowei Zhang, Qinxue Hu, Peng Zhou, Yuntao Wu, XianEn Zhan, Zongqiang Cui. Real-time imaging of single HIV-1 disassembly with multicolor viral particles. NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY, AND MEDICINE. 2018, 14(5): 1873-1873, http://dx.doi.org/10.1016/j.nano.2017.11.353.
[13] Qi, Mi, Zhang, XianEn, Sun, Xianxun, Zhang, Xiaowei, Yao, Yanfeng, Liu, Siling, Chen, Ze, Li, Wei, Zhang, Zhiping, Chen, Jianjun, Cui, Zongqiang. Intranasal Nanovaccine Confers Homo- and Hetero-Subtypic Influenza Protection. SMALL[J]. 2018, 14(13): http://www.corc.org.cn/handle/1471x/2373324.
[14] Li, Qin, Yin, Wen, Li, Wei, Zhang, Zhiping, Zhang, Xiaowei, Zhang, XianEn, Cui, Zongqiang. Encapsulating Quantum Dots within HIV-1 Virions through Site-Specific Decoration of the Matrix Protein Enables Single Virus Tracking in Live Primary Macrophages. NANO LETTERS[J]. 2018, 18(12): 7457-7468, http://202.127.146.157/handle/2RYDP1HH/6293.
[15] Yin, Wen, Li, Wei, Li, Qin, Qin, Chong, Zhang, Zhiping, Zhang, Xiaowei, Zhang, XianEn, Cui, Zongqiang. Structural Characterization and Analysis of Human Immunodeficiency Virus Encapsulating Quantum Dots. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2018, 18(7): 4487-4494, http://www.corc.org.cn/handle/1471x/2373339.
[16] Chen, Minghai, Li, Wei, Zhang, ZhiPing, Pan, Jingdi, Sun, Yuhan, Zhang, Xiaowei, Zhang, XianEn, Cui, Zongqiang. Three-Fragment Fluorescence Complementation for Imaging of Ternary Complexes under Physiological Conditions. ANALYTICAL CHEMISTRY[J]. 2018, 90(22): 13299-13305, http://www.corc.org.cn/handle/1471x/2373219.
[17] Fayyadh, Thaer Kadhim, Ma, Fuying, Qin, Chong, Zhang, Xiaowei, Li, Wei, Zhang, XianEn, Zhang, Zhiping, Cui, Zongqiang. Simultaneous detection of multiple viruses in their co-infected cells using multicolour imaging with self-assembled quantum dot probes. MICROCHIMICA ACTA[J]. 2017, 184(8): 2815-2824, http://202.127.146.157/handle/2RYDP1HH/4309.
[18] Zhang, Xiaowei, Qin, Chong, Li, Wei, Zhene, Zhenhua, Wang, Hanzhong, Cui, Zongqiang. Isolation and characterization of a highly evolved type 3 vaccine-derived poliovirus in China. VIRUS RESEARCH[J]. 2017, 238: 179-182, http://www.corc.org.cn/handle/1471x/2373382.
[19] Ma, Yingxin, Wang, Mingxiu, Li, Wei, Zhang, Zhiping, Zhang, Xiaowei, Wu, Guoqiang, Tan, Tianwei, Cui, Zongqiang, Zhang, XianEn. Live Visualization of HIV-1 Proviral DNA Using a Dual-Color-Labeled CRISPR System. ANALYTICAL CHEMISTRY[J]. 2017, 89(23): 12896-12901, http://202.127.146.157/handle/2RYDP1HH/4452.
[20] Li, Qin, Li, Wei, Yin, Wen, Guo, Jia, Zhang, ZhiPing, Zeng, Dejun, Zhang, Xiaowei, Wu, Yuntao, Zhang, XianEn, Cui, Zongqiang. Single-Particle Tracking of Human Immunodeficiency Virus Type 1 Productive Entry into Human Primary Macrophages. ACS NANO[J]. 2017, 11(4): 3890-3903, http://www.corc.org.cn/handle/1471x/2373406.
[21] Yingxin Ma, Mingxiu Wang, Wei Li, Zhiping Zhang, Xiaowei Zhang, Tianwei Tan, XianEn Zhang, Zongqiang Cui. Live cell imaging of single genomic loci with quantum dot-labeled TALEs. NATURE COMMUNICATIONS[J]. 2017, 8(1): http://www.corc.org.cn/handle/1471x/2373403.
[22] Chen, Minghai, Liu, Sanying, Li, Wei, Zhang, Zhiping, Zhang, Xiaowei, Zhang, XianEn, Cui, Zongqiang. Three-Fragment Fluorescence Complementation Coupled with Photoactivated Localization Microscopy for Nanoscale Imaging of Ternary Complexes. ACS NANO[J]. 2016, 10(9): 8482-8490, http://www.corc.org.cn/handle/1471x/2375027.
[23] Ma, Yingxin, Cui, Zongqiang, He, Zhike, Li, Wei, Zhang, Zhiping, Zhang, Xiaowei, Zhang, XianEn, Tan, Tianwei. Delaying Photobleaching of a Light-Switch Complex for Real-Time Imaging of Single Viral Particle Uncoating. ANALYTICAL CHEMISTRY[J]. 2016, 88(21): 10675-10679, https://www.webofscience.com/wos/woscc/full-record/WOS:000386991200049.
[24] Ma, Yingxin, He, Zhike, Tan, Tianwei, Li, Wei, Zhang, Zhiping, Song, Shuang, Zhang, Xiaowei, Hu, Qinxue, Zhou, Peng, Wu, Yuntao, Zhang, XianEn, Cui, Zongqiang. Real-Time Imaging of Single HIV-1 Disassembly with Multicolor Viral Particles. ACS NANO[J]. 2016, 10(6): 6273-6282, https://www.webofscience.com/wos/woscc/full-record/WOS:000378973700076.
[25] Zhang, Xiaowei, Zhang, Fei, Ma, Xiaohe, Zhao, Xing, Li, Wei, Zhang, Zhiping, Zhang, Jibin, Zhang, XianEn, Cui, Zongqiang. Identification of interaction between HIV-1 glycoprotein 41 and integrase. VIROLOGICA SINICA[J]. 2016, 31(5): 415-424, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193419/.
[26] Sun, Xianxun, Li, Wei, Zhang, Xiaowei, Qi, Mi, Zhang, Zhiping, Zhang, XianEn, Cui, Zongqiang. In Vivo Targeting and Imaging of Atherosclerosis Using Multifunctional Virus-Like Particles of Simian Virus 40. NANO LETTERS[J]. 2016, 16(10): 6164-6171, http://www.corc.org.cn/handle/1471x/2374899.
[27] Gao, Ding, Lin, XiuPing, Zhang, ZhiPing, Li, Wei, Men, Dong, Zhang, XianEn, Cui, ZongQiang. Intracellular cargo delivery by virus capsid protein-based vehicles: From nano to micro. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE[J]. 2016, 12(2): 365-376, http://dx.doi.org/10.1016/j.nano.2015.12.028.
[28] Chen, Minghai, Li, Wei, Zhang, Zhiping, Liu, Sanying, Zhang, Xiaowei, Zhang, XianEn, Cui, Zongqiang. Novel near-infrared BiFC systems from a bacterial phytochrome for imaging protein interactions and drug evaluation under physiological conditions. BIOMATERIALS[J]. 2015, 48: 97-107, http://dx.doi.org/10.1016/j.biomaterials.2015.01.038.
[29] Wang, Jingyi, Liu, Ru, Su, Yunming, Li, Wei. Embedded Carbon Nanotubes Nanoparticles in Plasma Membrane Induce Cellular Calcium Outflow Imbalancing. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2014, 14(6): 4058-4065, http://ir.ihep.ac.cn/handle/311005/225125.
[30] Han, Yu, Wang, Shifeng, Zhang, Zhiping, Ma, Xiaohe, Li, Wei, Zhang, Xiaowei, Deng, Jiaoyu, Wei, Hongping, Li, Zhaoyang, Zhang, XianEn, Cui, Zongqiang. In vivo imaging of protein-protein and RNA-protein interactions using novel far-red fluorescence complementation systems. NUCLEIC ACIDS RESEARCH[J]. 2014, 42(13): e103-e103, https://www.webofscience.com/wos/woscc/full-record/WOS:000341515400001.
[31] Chen, Qianqian, Zhang, Juan, Zhao, Kai, Li, Wei, Miao, Qi, Sun, Yang, Zhao, Xingyu, Wei, Taotao, Yang, Fuyu. Lysosomal chymotrypsin induces mitochondrial fission in apoptotic cells by proteolytic activation of calcineurin. PROTEIN & CELL[J]. 2014, 5(8): 643-647, [32] Duan, Wenjuan, Zhou, Juefei, Li, Wei, Zhou, Teng, Chen, Qianqian, Yang, Fuyu, Wei, Taotao. Plasma membrane calcium ATPase 4b inhibits nitric oxide generation through calcium-induced dynamic interaction with neuronal nitric oxide synthase. PROTEIN & CELL[J]. 2013, 4(4): 286-298, [33] Li, Wei, Liu, Ru, Wang, Yaling, Zhao, Yuliang, Gao, Xueyun. Temporal Techniques: Dynamic Tracking of Nanomaterials in Live Cells. SMALL[J]. 2013, 9(9-10): 1585-1594, http://dx.doi.org/10.1002/smll.201201508.
[34] Wang, Liming, Liu, Ying, Li, Wei, Jiang, Xiumei, Ji, Yinglu, Wu, Xiaochun, Xu, Ligeng, Qiu, Yang, Zhao, Kai, Wei, Taotao, Li, Yufeng, Zhao, Yuliang, Chen, Chunying. Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy. NANO LETTERS[J]. 2011, 11(2): 772-780, [35] 赵宇亮. Full assessment of fate and physiological behavior of quantum dots utilizing Caenorhabditis elegans as a model organism. NANO LETTERS[J]. 2011, 11(8): 3174-3183, http://www.corc.org.cn/handle/1471x/2176084.
[36] Li, Wei, Zhao, Lina, Wei, Taotao, Zhao, Yuliang, Chen, Chunying. The inhibition of death receptor mediated apoptosis through lysosome stabilization following internalization of carboxyfullerene nanoparticles. BIOMATERIALS[J]. 2011, 32(16): 4030-4041, [37] Li Wei. Intracellular dynamics of cationic and anion polystyrene nanoparticles without direct interaction with mitotic spindle and chromosomes. Biomaterials. 2011, [38] 赵宇亮. Fullerene Nanoparticles Selectively Enter Oxidation-Damaged Cerebral Microvessel Endothelial Cells and Inhibit JNK-Related Apoptosis. ACS NANO[J]. 2009, 3(11): 3358-3368, http://dx.doi.org/10.1021/nn900912n.
[39] 赵宇亮. Cellular Biological Effects of Carbon Nanomaterials. PROGRESS IN CHEMISTRY[J]. 2009, 21(2-3): 430-435, http://ir.ihep.ac.cn/handle/311005/237459.
[40] 赵宇亮. The translocation of fullerenic nanoparticles into lysosome via the pathway of clathrin-mediated endocytosis. NANOTECHNOLOGY[J]. 2008, 19(14): 145102-, http://ir.ihep.ac.cn/handle/311005/241004.
[41] Li Wei. An Accurate and Quantitative Analytical Method for Metal Impurities in Carbon Nanotubes: ICP-MS coupled with Neutron Activation and protocol for sample pretreatment. Anal. Chem. 2008, [42] Zhang, S, Li, W, Gao, QH, Wei, TT. Effect of melatonin on the generation of nitric oxide in murine macrophages. EUROPEAN JOURNAL OF PHARMACOLOGY[J]. 2004, 501(1-3): 25-30, http://dx.doi.org/10.1016/j.ejphar.2004.08.015.
[43] Li, W, Zhang, S, Gao, QH, Hou, JW, Wei, TT. Different effects of ferulic acid and tetramethylpyrazine on the production of superoxide anion and nitric oxide in murine macrophages. RESEARCH ON CHEMICAL INTERMEDIATESnull. 2004, 30(6): 605-613, https://www.webofscience.com/wos/woscc/full-record/WOS:000223789900003.