​    刘䶮(YAN)，博士，副研究员，硕士生导师。2006年本科毕业于江南大学食品学院，2009年硕士毕业于清华大学医学部&北京协和医学院，2009年起在中国科学院福建物质结构研究所工作，历任研究实习员、助理研究员、副研究员，2017年获得中国科学院大学博士学位。曾作为项目负责人先后主持过国家自然科学基金、福建省自然科学基金、中央级公益性科研专项等科研项目。目前已在Angew. Chem. Int. Edit., Chem. Eng. J., Nano Res., Carbohyd. Polym., Nanoscale, Int. J. Nanomed., Food Chem., Talanta, J. Biomol. Struct. Dyn., Food Chem. Toxicol., Mol. Syst. Des. Eng., Colloid Surface B., J. Lumin., J. Mol. Recognit., Environ. Sci. Pollut. R., J. Biochem. Mol. Toxic.等期刊发表学术论文50余篇。

目前从事研究方向：

 1、稀土纳米晶的光、酶、磁特性及其生物应用

 2、生物分子自组装、纳米界面活性及手性光学效应

2013-09--2017-05   中国科学院大学   博士研究生
2006-09--2009-05   清华大学医学部&北京协和医学院   硕士研究生
2002-09--2006-05   江南大学食品学院   本科

   

（ 1 ） 一种近红外染料共配位型纳米配位聚合物及其制备方法和应用, 专利授权, 2021, 第 3 作者, 专利号: CN111135313B

（ 2 ） 一种无载体纳米诊疗剂及其制备方法和应用, 发明专利, 2021, 第 3 作者, 专利号: 2021108233245

（ 3 ） 一种基于双激发比率型上转换荧光探针的胞内检测方法, 发明专利, 2021, 专利号: CN112444505A

（ 4 ） 一种基于纳米探针检测过氧化氢和相关目标物的方法, 专利授权, 2020, 专利号: CN110411990B

（ 5 ） 稀土掺杂碱土金属氟卤化物纳米发光材料及其制备方法和应用, 专利授权, 2020, 专利号: CN110358532B

（ 6 ） 一种基于CaS纳米荧光探针检测过氧化氢和相关目标物的方法, 发明专利, 2020, 专利号: CN111829993A

（ 7 ） 一种荧光量子点纳米探针、其制备方法及其检测循环肿瘤细胞的应用, 发明专利, 2020, 第 5 作者, 专利号: 202010666311.7

（ 8 ） 反相微乳液法合成稀土生物有机配位纳米探针及合成方法, 发明专利, 2020, 第 1 作者, 专利号: 202010544069.6

（ 9 ） 一种基于稀土金属的酶响应型探针及其制备方法和应用, 发明专利, 2020, 专利号: 202010140295.8

（ 10 ） 一种基于多巴胺聚合反应调控的上转换荧光共振能量传递检测组合物及检测方法, 专利授权, 2019, 专利号: CN107402198B

（ 11 ） 一种基于酶诱导磷酸根离子激活的近红外荧光免疫分析试剂盒及检测方法, 发明专利, 2018, 专利号: ZL 2018 1 1565498.0

（ 12 ） 一种基于稀土纳米材料荧光放大的microRNA检测方法, 发明专利, 2017, 专利号: CN107012210A

（ 13 ） 一种光学纯2-氨基-2’-羟基-1,1’-联萘的酶拆分方法, 发明专利, 2012, 第 2 作者, 专利号: CN102409074A

（ 14 ） 胆甾化壳聚糖纳米载体及其载药纳米粒子和制造方法, 发明专利, 2010, 专利号: CN101850122A

   

[1] 张云钦, 曹洋, 刘䶮, 杨颖婕, 陈名懋, 高航, 林璐珊, 陈学元. Time-Resolved Luminescent Nanoprobes Based on Lanthanide Nucleotide Self-Assemblies for Alkaline Phosphatase Detection. Nano Res.[J]. 2023, [2] 刘若湄, 冯艳辉, 李卓, 卢珊, 关天用, 李幸俊, 刘䶮, 陈卓, 陈学元. A novel near-infrared responsive lanthanide upconversion nanoplatform for drug delivery based on photocleavage of cypate. Acta Chim. Sinica[J]. 2022, 80(4): 423-427, http://sioc-journal.cn/Jwk_hxxb/CN/10.6023/A22010001.
[3] Yang, Yingjie, Liu, Yan, Tu, Datao, Chen, Mingmao, Zhang, Yunqin, Gao, Hang, Chen, Xueyuan. Tumor-Microenvironment-Responsive Biodegradable Nanoagents Based on Lanthanide Nucleotide Self-Assemblies toward Precise Cancer Therapy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 61(14): http://dx.doi.org/10.1002/anie.202116983.
[4] Yan Liu, Jia Tian, Yulei Fu, Yingjie Yang, Mingmao Chen, Qiqing Zhang. Near-infrared light-triggered nanobomb for in situ on-demand maximizing photothermal/photodynamic efficacy for cancer therapy. Biomater. Sci.[J]. 2021, 9: 700-711, [5] Gao, Hang, Zhang, Peng, Guan, Tianyong, Yang, Yingjie, Chen, Mingmao, Wei, Jiaojiao, Han, Siyuan, Liu, Yan, Chen, Xueyuan. Rapid and accurate detection of phosphate in complex biological fluids based on highly improved antenna sensitization of lanthanide luminescence. TALANTA[J]. 2021, 231: 122243-, http://dx.doi.org/10.1016/j.talanta.2021.122243.
[6] Chen, Mingmao, Li, Ruyue, Liu, Yan, Song, Xiaorong, Tian, Jia, Fu, Yulei, Yang, Yingjie, Liu, Chun, Zhang, Qiqing. Near infrared and pH dual-activated coordination polymer nanosystem for imaging-guided chemo-photothermal therapy. CHEMICAL ENGINEERING JOURNAL[J]. 2021, 406: 126745-, http://dx.doi.org/10.1016/j.cej.2020.126745.
[7] Liu, Yan, Tian, Jia, Fu, Yulei, Yang, Yingjie, Chen, Mingmao, Zhang, Qiqing. Near-infrared light-triggered nanobomb for in situ on-demand maximization of photothermal/photodynamic efficacy for cancer therapy. BIOMATERIALS SCIENCE[J]. 2021, 9(3): 700-711, https://www.webofscience.com/wos/woscc/full-record/WOS:000616677300007.
[8] Wei, Jiaojiao, Zheng, Wei, Huang, Ping, Gong, Zhongliang, Liu, Yan, Lu, Shan, Li, Zhuo, Chen, Xueyuan. Direct photoinduced synthesis of lead halide perovskite nanocrystals and nanocomposites. NANO TODAY[J]. 2021, 39: 101179-, http://dx.doi.org/10.1016/j.nantod.2021.101179.
[9] Zhou, Shanyong, Tu, Datao, Liu, Yan, You, Wenwu, Zhang, Yunqin, Zheng, Wei, Chen, Xueyuan. Ultrasensitive Point-of-Care Test for Tumor Marker in Human Saliva Based on Luminescence-Amplification Strategy of Lanthanide Nanoprobes. ADVANCED SCIENCE[J]. 2021, 8(5): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927602/.
[10] Huang, Ping, Zheng, Wei, Tu, Datao, Shang, Xiaoying, Zhang, Meiran, Li, Renfu, Xu, Jin, Liu, Yan, Chen, Xueyuan. Unraveling the Electronic Structures of Neodymium in LiLuF4 Nanocrystals for Ratiometric Temperature Sensing. ADVANCED SCIENCE[J]. 2019, 6(10): 1802282-, https://doaj.org/article/d32efe4186ce47a8a648a38dfd058838.
[11] Chen, Mingmao, Song, Feifei, Liu, Yan, Tian, Jia, Liu, Chun, Li, Ruyue, Zhang, Qiqing. A dual pH-sensitive liposomal system with charge-reversal and NO generation for overcoming multidrug resistance in cancer. NANOSCALE[J]. 2019, 11(9): 3814-3826, [12] Li, Xingjun, Zhou, Shanyong, Lu, Shan, Tu, Datao, Zheng, Wei, Liu, Yan, Li, Renfu, Chen, Xueyuan. Lanthanide Metal-Organic Framework Nanoprobes for the In Vitro Detection of Cardiac Disease Markers. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(47): 43989-43995, http://dx.doi.org/10.1021/acsami.9b17637.
[13] Jianxi Ke, Shan Lu, Xiaoying Shang, Yan Liu, Hanhan Guo, Wenwu You, Xingjun Li, Jin Xu, Renfu Li, Zhuo Chen, Xueyuan Chen. A Strategy of NIR Dual‐Excitation Upconversion for Ratiometric Intracellular Detection. ADVANCED SCIENCE[J]. 2019, 6(22): n/a-n/a, https://doaj.org/article/5a21835e8fc44375bd0e6daa31466548.
[14] Wei, Jiaojiao, Zheng, Wei, Shang, Xiaoying, Li, Renfu, Huang, Ping, Liu, Yan, Gong, Zhongliang, Zhou, Shanyong, Chen, Zhuo, Chen, Xueyuan. Mn2+-activated calcium fluoride nanoprobes for time-resolved photoluminescence biosensing. SCIENCE CHINA-MATERIALS[J]. 2019, 62(1): 130-137, https://www.webofscience.com/wos/woscc/full-record/WOS:000455325400014.
[15] Zhang, Meiran, Zheng, Wei, Liu, Yan, Huang, Ping, Gong, Zhongliang, Wei, Jiaojiao, Gao, Yu, Zhou, Shanyong, Li, Xingjun, Chen, Xueyuan. A New Class of Blue-LED-Excitable NIR-II Luminescent Nanoprobes Based on Lanthanide-Doped CaS Nanoparticles. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(28): 9556-9560, [16] Chen, Mingmao, Tian, Jia, Liu, Yan, Cao, Huan, Li, Ruyue, Wang, Jianhua, Wu, Jiulin, Zhang, Qiqing. Dynamic covalent constructed self-healing hydrogel for sequential delivery of antibacterial agent and growth factor in wound healing. CHEMICAL ENGINEERING JOURNAL[J]. 2019, 373: 413-424, http://dx.doi.org/10.1016/j.cej.2019.05.043.
[17] Yan Liu, Datao Tu, Wei Zheng, Lianyu Lu, Wenwu You, Shanyong Zhou, Ping Huang, Renfu Li, Xueyuan Chen. A strategy for accurate detection of glucose in human serum and whole blood based on an upconversion nanoparticles-polydopamine nanosystem. NANO RESEARCH,[J]. 2018, 11(6): 3164-3174, https://www.webofscience.com/wos/woscc/full-record/WOS:000433048600019.
[18] Chen, MingMao, Song, FeiFei, Feng, Mei, Liu, Yan, Liu, YuanYuan, Tian, Jia, Lv, Feng, Zhang, QiQing. pH-sensitive charge-conversional and NIR responsive bubble-generating liposomal system for synergetic thermo-chemotherapy. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2018, 167: 104-114, http://dx.doi.org/10.1016/j.colsurfb.2018.04.001.
[19] Liu, Yan, Jiang, Longguang, Song, Ling, Tu, Datao, Zheng, Wei, Huang, Ping, Chen, Mingmao, Chen, Xueyuan. Deciphering molecular interaction of binaphthyl compounds with Penicillium expansum lipase: enantioselectivity and reactivity prediction for lipase. MOLECULAR SYSTEMS DESIGN & ENGINEERING[J]. 2018, 3(4): 658-667, https://www.webofscience.com/wos/woscc/full-record/WOS:000441582300008.
[20] Yan, Shufeng, Song, Xiaorong, Liu, Yan, Dai, Tao, Huang, Mingdong, Chen, Xueyuan, Chen, Zhuo. An efficient synergistic cancer therapy by integrating cell cycle inhibitor and photosensitizer into polydopamine nanoparticles. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2018, 6(17): 2620-2629, https://www.webofscience.com/wos/woscc/full-record/WOS:000431421800014.
[21] Lei, Xialian, Li, Renfu, Tu, Datao, Shang, Xiaoying, Liu, Yan, You, Wenwu, Sun, Caixia, Zhang, Fan, Chen, Xueyuan. Intense near-infrared-II luminescence from NaCeF4:Er/Yb nanoprobes for in vitro bioassay and in vivo bioimaging. CHEMICAL SCIENCE[J]. 2018, 9(20): 4682-4688, https://www.webofscience.com/wos/woscc/full-record/WOS:000433426700016.
[22] Lu, Lianyu, Tu, Datao, Liu, Yan, Zhou, Shanyong, Zheng, Wei, Chen, Xueyuan. Ultrasensitive detection of cancer biomarker microRNA by amplification of fluorescence of lanthanide nanoprobes. NANO RESEARCH[J]. 2018, 11(1): 264-273, https://www.webofscience.com/wos/woscc/full-record/WOS:000419002100021.
[23] Liu, Yan, Tu, Datao, Zheng, Wei, Lu, Lianyu, You, Wenwu, Zhou, Shanyong, Huang, Ping, Li, Renfu, Chen, Xueyuan. A strategy for accurate detection of glucose in human serum and whole blood based on an upconversion nanoparticles-polydopamine nanosystem. NANO RESEARCH[J]. 2018, 11(6): 3164-3174, http://lib.cqvip.com/Qikan/Article/Detail?id=675560639.
[24] You, Wenwu, Tu, Datao, Zheng, Wei, Shang, Xiaoying, Song, Xiaorong, Zhou, Shanyong, Liu, Yan, Li, Renfu, Chen, Xueyuan. Large-scale synthesis of uniform lanthanide-doped NaREF4 upconversion/downshifting nanoprobes for bioapplications. NANOSCALE[J]. 2018, 10(24): 11477-11484, https://www.webofscience.com/wos/woscc/full-record/WOS:000436133400028.
[25] Chen, MingMao, Cao, Huan, Liu, YuanYuan, Liu, Yan, Song, FeiFei, Chen, JingDi, Zhang, QiQing, Yang, WenZhi. Sequential delivery of chlorhexidine acetate and bFGF from PLGA-glycol chitosan core-shell microspheres. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2017, 151: 189-195, http://dx.doi.org/10.1016/j.colsurfb.2016.05.045.
[26] Chen MM, Liu YY, Su GH, Song FF, Liu Y, Zhang QQ. NIR responsive liposomal system for rapid release of drugs in cancer therapy. INTERNATIONAL JOURNAL OF NANOMEDICINE[J]. 2017, 12: 4225-4239, https://doaj.org/article/683f7901c2fc4a2b8501ac59fbd034bc.
[27] Zhou, Zhihao, Zheng, Wei, Kong, Jintao, Liu, Yan, Huang, Ping, Zhou, Shanyong, Chen, Zhuo, Shi, Jianlin, Chen, Xueyuan. Rechargeable and LED-activated ZnGa2O4 : Cr3+ near-infrared persistent luminescence nanoprobes for background-free biodetection. NANOSCALE[J]. 2017, 9(20): 6846-6853, http://ir.sic.ac.cn/handle/331005/25404.
[28] Chen, Mingmao, Liu, Yan, Cao, Huan, Song, Ling, Zhang, Qiqing. The secondary and aggregation structural changes of BSA induced by trivalent chromium: A biophysical study (vol 158, pg 116, 2015). JOURNAL OF LUMINESCENCEnull. 2016, 175: 274-274, https://www.webofscience.com/wos/woscc/full-record/WOS:000374865800043.
[29] Yan Liu, Mingmao Chen, Longguang Jiang, Ling Song. Corrigendum to "Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin" Food Chem. 181 (2015) 170–178. FOOD CHEMISTRY. 2016, 1349-1349, http://dx.doi.org/10.1016/j.foodchem.2015.11.125.
[30] Zheng, Wei, Zhou, Shanyong, Xu, Jin, Liu, Yongsheng, Huang, Ping, Liu, Yan, Chen, Xueyuan. Ultrasensitive Luminescent In Vitro Detection for Tumor Markers Based on Inorganic Lanthanide Nano-Bioprobes. ADVANCED SCIENCE[J]. 2016, 3(11): 1600197-, https://www.webofscience.com/wos/woscc/full-record/WOS:000387649100015.
[31] Lin, Jingjing, Liu, Yan, Chen, Mingmao, Huang, Huayin, Song, Ling. Investigation on the binding activities of citalopram with human and bovine serum albumins (vol 146, pg 114, 2014). JOURNAL OF LUMINESCENCEnull. 2016, 170: 336-336, https://www.webofscience.com/wos/woscc/full-record/WOS:000365606600050.
[32] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. New insight into molecular interaction of heavy metal pollutant-cadmium(II) with human serum albumin (vol 21, pg 6994 2014). ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCHnull. 2016, 23(5): 4959-4959, https://www.webofscience.com/wos/woscc/full-record/WOS:000371156100095.
[33] Mingmao Chen, Yan Liu, Huan Cao, Ling Song, Qiqing Zhang. Corrigendum to: "The secondary and aggregation structural changes of BSA induced by trivalent chromium: A biophysical study" J. Lumin. 158 (2015) 116–124. JOURNAL OF LUMINESCENCE. 2016, 175: 274-274, http://dx.doi.org/10.1016/j.jlumin.2016.01.002.
[34] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin (vol 181, pg 170, 2015). FOOD CHEMISTRYnull. 2016, 197: 1349-1349, https://www.webofscience.com/wos/woscc/full-record/WOS:000366987500043.
[35] Chen, Mingmao, Liu, Yan, Cao, Huan, Song, Ling, Zhang, Qiqing. The secondary and aggregation structural changes of BSA induced by trivalent chromium: A biophysical study. JOURNAL OF LUMINESCENCE[J]. 2015, 158: 116-124, http://dx.doi.org/10.1016/j.jlumin.2014.09.021.
[36] Liu, Yan, Lin, Jingjing, Chen, Mingmao, Song, Ling. Investigation on the interaction of the toxicant, gentian violet, with bovine hemoglobin (vol 58, pg 264, 2013). FOOD AND CHEMICAL TOXICOLOGYnull. 2015, 86: 385-385, https://www.webofscience.com/wos/woscc/full-record/WOS:000368203200041.
[37] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin. FOOD CHEMISTRY[J]. 2015, 181: 170-178, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201903250003887LS.
[38] Cao, Huan, Chen, MingMao, Liu, Yan, Liu, YuanYuan, Huang, YuQing, Wang, JianHua, Chen, JingDi, Zhang, QiQing. Fish collagen-based scaffold containing PLGA microspheres for controlled growth factor delivery in skin tissue engineering. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2015, 136: 1098-1106, http://dx.doi.org/10.1016/j.colsurfb.2015.10.022.
[39] Yan Liu, Jingjing Lin, Mingmao Chen, Ling Song. Corrigendum to "Investigation on the interaction of the toxicant, gentian violet, with bovine hemoglobin" Food Chem. Toxicol. 58 (2013) 264–272. FOOD AND CHEMICAL TOXICOLOGY. 2015, 86: 385-385, http://dx.doi.org/10.1016/j.fct.2015.11.006.
[40] Chen, MingMao, Huang, YuQing, Cao, Huan, Liu, Yan, Guo, Hao, Chen, Lillian S, Wang, JianHua, Zhang, QiQing. Collagen/chitosan film containing biotinylated glycol chitosan nanoparticles for localized drug delivery. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2015, 128: 339-346, http://dx.doi.org/10.1016/j.colsurfb.2015.02.024.
[41] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. Stereoselective interaction of cinchona alkaloid isomers with bovine serum albumin. FOOD CHEMISTRY[J]. 2015, 170-178, http://dx.doi.org/10.1016/j.foodchem.2015.02.040.
[42] Chen, MingMao, Huang, YuQing, Guo, Hao, Liu, Yan, Wang, JianHua, Wu, JiuLin, Zhang, QiQing. Preparation, Characterization, and Potential Biomedical Application of Composite Sponges Based on Collagen from Silver Carp Skin. JOURNAL OF APPLIED POLYMER SCIENCE[J]. 2014, 131(21): 40998-1-40998-8, https://www.webofscience.com/wos/woscc/full-record/WOS:000340401400033.
[43] Liu, Yan, Chen, Mingmao, Wang, Shuaihua, Lin, Jingjing, Cai, Lizhen, Song, Ling. New insight into the stereoselective interactions of quinine and quinidine, with bovine serum albumin. JOURNAL OF MOLECULAR RECOGNITION[J]. 2014, 27(5): 239-249, http://dx.doi.org/10.1002/jmr.2355.
[44] Lin, Jingjing, Liu, Yan, Chen, Mingmao, Huang, Huayin, Song, Ling. Investigation on the binding activities of citalopram with human and bovine serum albumins. JOURNAL OF LUMINESCENCE[J]. 2014, 146: 114-122, http://dx.doi.org/10.1016/j.jlumin.2013.09.054.
[45] Liu, Yan, Chen, Mingmao, Jiang, Longguang, Song, Ling. New insight into molecular interaction of heavy metal pollutant-cadmium(II) with human serum albumin. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH[J]. 2014, 21(11): 6994-7005, https://www.webofscience.com/wos/woscc/full-record/WOS:000336371000021.
[46] Chen, Mingmao, Guo, Hao, Liu, Yan, Zhang, Qiqing. Structural Changes of Human Serum Albumin Induced by Cadmium Acetate. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY[J]. 2014, 28(6): 281-287, https://www.webofscience.com/wos/woscc/full-record/WOS:000337621400006.
[47] Liu, Yan, Chen, Mingmao, Luo, Zhipu, Lin, Jingjing, Song, Ling. Investigation on the site-selective binding of bovine serum albumin by erlotinib hydrochloride. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS[J]. 2013, 31(10): 1160-1174, https://www.webofscience.com/wos/woscc/full-record/WOS:000324002100012.
[48] Liu, Yan, Liu, Lingrong, Chen, Mingmao, Zhang, Qiqing. Double thermal transitions of type I collagen in acidic solution. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS[J]. 2013, 31(8): 862-873, https://www.webofscience.com/wos/woscc/full-record/WOS:000321732100006.
[49] Liu, Yan, Lin, Jingjing, Chen, Mingmao, Song, Ling. Investigation on the interaction of the toxicant, gentian violet, with bovine hemoglobin. FOOD AND CHEMICAL TOXICOLOGY[J]. 2013, 58: 264-272, http://dx.doi.org/10.1016/j.fct.2013.04.048.
[50] Liu, Yan, Chen, Mingmao, Song, Ling. Comparing the effects of Fe(III) and Cu(II) on the binding affinity of erlotinib to bovine serum albumin using spectroscopic methods. JOURNAL OF LUMINESCENCE[J]. 2013, 134: 515-523, http://dx.doi.org/10.1016/j.jlumin.2012.07.036.
[51] Lin, Jingjing, Liu, Yan, Liu, Lingrong, Song, Ling. Studies on the Toxic Interaction Mechanism between 2-Naphthylamine and Herring Sperm DNA. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY[J]. 2013, 27(5): 279-285, http://www.corc.org.cn/handle/1471x/2221473.
[52] Ding, Lei, Lin, Lirong, Liu, Chengyong, Li, Hongkun, Qin, Anjun, Liu, Yan, Song, Ling, Zhang, Hui, Tang, Ben Zhong, Zhao, Yufen. Concentration effects in solid-state CD spectra of chiral atropisomeric compounds. NEW JOURNAL OF CHEMISTRY[J]. 2011, 35(9): 1781-1786, http://ir.fjirsm.ac.cn/handle/335002/1129.
[53] Liu, Yan, Chen, Mingmao, Bian, Guangling, Liu, Junfeng, Song, Ling. Spectroscopic investigation of the interaction of the toxicant, 2-naphthylamine, with bovine serum albumin. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY[J]. 2011, 25(6): 362-368, http://ir.fjirsm.ac.cn/handle/335002/1402.

   

（ 1 ） 基于稀土上转换纳米荧光探针的艾滋病早期标志物体外检测研究, 负责人, 国家任务, 2015-01--2017-12
（ 2 ） 基于多元滴定发光体系对手性药物对映体拮抗/协同作用的研究, 负责人, 地方任务, 2013-01--2015-12
（ 3 ） 基于稀土上转换纳米探针的艾滋病早期标志物检测应用研究, 负责人, 地方任务, 2018-01--2020-12
（ 4 ） 稀土掺杂钙钛矿量子点荧光探针：控制合成、光学性能和生物应用, 参与, 国家任务, 2018-01--2021-12
（ 5 ） 高效染料敏化稀土上转换荧光探针及其肿瘤标志物体外检测应用, 参与, 国家任务, 2017-01--2020-12
（ 6 ） 复合型芳香胺类环境污染物与人血清白蛋白相互作用及复合效应的研究, 参与, 国家任务, 2013-01--2015-12
（ 7 ） 纳米生物标记材料及应用研究团队-8, 参与, 其他任务, 2015-01--2017-12
（ 8 ） 体外模拟金属离子作用下手性抗抑郁药与人体血液载体蛋白识别模式差异性及复合效应的分子机制研究, 负责人, 地方任务, 2012-01--2012-12
（ 9 ） 致癌物1-萘胺 / 2-萘胺与人血清白蛋白复合作用的分子机制研究, 负责人, 地方任务, 2013-01--2013-12
（ 10 ） 基于稀土纳米荧光探针的唾液肿瘤标志物体外检测, 参与, 国家任务, 2018-01--2021-12
（ 11 ） 基于稀土氧化物纳米晶聚集体探针的痕量肿瘤标志物荧光免疫分析, 负责人, 地方任务, 2021-11--2024-11