070302-分析化学
071011-生物物理学
0703J1-纳米科学与技术

光谱电化学
纳米生物界面分析
纳米细胞相互作用

2002-09--2005-12   中国科学院长春应用化学研究所   博士学位
1999-09--2002-07   东北师范大学   硕士学位
1995-09--1999-07   辽宁石油化工大学   学士学位

   

2010-09~现在, 中国科学院长春应用化学研究所电分析化学国家重点实验室, 研究员，博士生导师
2010-01~2010-04,德国Karlsruhe技术研究所, 博士后
2008-06~2009-12,德国Ulm大学, 博士后
2006-04~2008-05,德国Bielefeld大学, 洪堡学者
2002-09~2005-12,中国科学院长春应用化学研究所, 博士学位
1999-09~2002-07,东北师范大学, 硕士学位
1995-09~1999-07,辽宁石油化工大学, 学士学位

   

（ 1 ） 一种提高表面增强红外吸收光谱的增强因子的方法, 2016, 第 2 作者, 专利号: 201210418056.X

（ 2 ） 一种C3N4纳米复合材料、制备方法及其应用, 2015, 第 1 作者, 专利号: 201510979958.4

（ 3 ） 一种Bi2Te3二维纳米片、其制备方法及应用, 2015, 第 1 作者, 专利号: 201510454096.3

（ 4 ） 一种红外光谱仪反射附件, 2014, 第 1 作者, 专利号: ZL201210101360.1

   

（1） Recent developments in methodology employed to study the interactions between nanomaterials and model lipid membranes, Analytical and Bioanalytical Chemistry, 2016, 通讯作者
（2） Polycatechol nanosheet: a superior nanocarrier for, Nanoscale, 2016, 通讯作者
（3） Breaking of the Phosphodiester Bond: A Key Factor That Induces Hemolysis, ACS Applied Materials & Interfaces, 2015, 通讯作者
（4） Fabrication of Multifunctional SiO2@GN-Serum Composites for Chemo-Photothermal Synergistic Therapy, ACS Applied Materials & Interfaces, 2015, 通讯作者
（5） Toxicity mechanism of graphene oxide and nitrogen-doped graphene quantum dots in RBCs revealed by surface-enhanced infrared absorption spectroscopy, Toxicology Research, 2015, 通讯作者
（6） Monitoring of the Enzymatic Degradation of Protein Corona and Evaluating the Accompanying Cytotoxicity of Nanoparticles, ACS Applied Materials & Interfaces, 2015, 通讯作者
（7） Large mesoporous carbons decorated with silver and gold nanoparticles by a self-assembly method: enhanced electrocatalytic activity for H2O2 electroreduction and sodium nitrite electrooxidation, RSC Advances, 2015, 通讯作者
（8） Label-Free Surface-Enhanced Infrared Spectroelectrochemistry Studies the Interaction of Cytochrome c with Cardiolipin-Containing Membranes, The Journal of Physical Chemistry C, 2015, 通讯作者
（9） Revealing the Nature of Interaction between Graphene Oxide and Lipid Membrane by Surface-Enhanced Infrared Absorption Spectroscopy, Journal of the American Chemical Society, 2015, 通讯作者
（10） Label-free surface-enhanced infrared spectro-electro-chemical analysis of the Redox potential shift of cytochrome c complexed with a cardiolipin-containing lipid membrane of varied composition, Chinese Physics B, 2015, 通讯作者
（11） Nanoparticle interactions with live cells: Quantitative fluorescence microscopy of nanoparticle size effects, Beilstein Journal of nanotechnology, 2014, 第 3 作者
（12） Effects of nanoparticle surface ligands on protein adsorption and subsequent cytotoxicity, Biomaterials Science, 2014, 通讯作者
（13） Impact of Shape and Pore Size of Mesoporous Silica Nanoparticles on Serum Protein Adsorption and RBCs Hemolysis, ACS Applied Materials & Interfaces, 2014, 通讯作者
（14） Multifunctional PEG-GO/CuS nanocomposites for near-infrared chemo-photothermal therapy, Biomaterials, 2014, 通讯作者
（15） Hydrogen Peroxide Biosensor Based on Carbon Supported Ultrafine Silver Nanoparticles, Chinese Journal of Analytical Chemistry, 2014, 通讯作者
（16） A sensitive hydrogen peroxide and glucose biosensor based on gold/silver core-shell nanorods, Electrochimica Acta, 2013, 通讯作者
（17） Investigation of the effects of surface chemistry on adsorption of albumin by surface-enhanced FTIR spectroscopy, RSC Advances, 2013, 通讯作者
（18） A Facile One-Pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites for Enhanced Detecting of H2O2 in Biological Environments, Analytical Chemistry, 2013, 通讯作者
（19） New views on cellular uptake and trafficking of manufactured nanoparticles, Journal of the Royal Society Interface, 2013, 第 2 作者
（20） Facile Preparation of Porous Carbon Nanosheets without Template and Their Excellent Electrocatalytic Property, ACS Applied Materials & Interfaces, 2013, 通讯作者
（21） Facile-green synthesis of nitrogen-doped carbon-supported ultrafine silver catalyst with enhanced electrocatalytic property, Electrochimica Acta, 2013, 通讯作者
（22） High sensitivity hydrogen peroxide and hydrazine sensor based on silver nanocubes with rich {100} facets as an enhanced electrochemical sensing platform, Biosensors and Bioelectronics, 2013, 通讯作者
（23） Size-Dependent Stability of Water-Solubilized CdTe Quantum Dots and Their Uptake Mechanism by Live HeLa Cells, ACS Appl. Mater. Interfaces, 2013, 通讯作者
（24） Bioanalytical Applications of Surface-enhanced Infrared Absorption Spectroscopy, Chinese Journal of Analytical Chemistry, 2012, 通讯作者
（25） Adsorption orientation of horse heart cytochrome c on a bare gold electrode hampers its electron transfer, J. Phys. Chem. C, 2012, 通讯作者
（26） Cellular uptake of nanoparticles by membrane penetration: a study combining confocal microscopy with FTIR spectroelectrochemistry, ACS nano, 2012, 通讯作者
（27） Hydrogen peroxide and glucose biosensor based on silver nanowires synthesized by polyol process, Analyst, 2012, 通讯作者
（28） Specific effects of surface carboxyl groups on anionic polystyrene particles in their interactions with mesenchymal stem cells, Nanoscale, 2011, 第 1 作者
（29） The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages, Biomaterials, 2010, 第 4 作者
（30） Specific effects of surface amines on polystyrene nanoparticles in their interactions with mesenchymal stem cells,  Biomacromolecules, 2010, 第 1 作者
（31）  Endo- and exocytosis of zwitterionic quantum dot nanoparticles by live HeLa cells, ACS nano, 2010, 第 1 作者
（32） Molecular impact of the membrane potential on the regulatory mechaism of proton transfer in sensory rhodopsin II , J. Am. Chem. Soc., 2010, 第 1 作者
（33） Quantitative analysis of the protein corona on FePt nanoparticles formed by transferrin binding, Journal of The Royal Society Interface, 2010, 第 1 作者
（34） Influence of the molecular structure of carboxyl-terminated self-assembled monolayer on the electron transfer of cytochrome c adsorbed on an an electrode: In situ observation by surface-enhanced infrared absorption spectroscopy, Journal of Physical Chemistry C, 2008, 第 1 作者
（35） In Situ monitoring of the orientated assembly of strep-tagged membrane proteins on the gold surface by surface enhanced infrared absorption spectroscopy, Physical Chemistry Chemical Physics, 2008, 第 1 作者
（36） Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy. Proceedings of the national academy of sciences, Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2008, 第 1 作者
（37） Investigations on the adsorption behavior of Neutral Red on mercaptoethane sulfonate protected gold nanoparticles, Journal of Photochemistry and Photobiology A-Chemistry, 2007, 第 3 作者
（38） 电化学氧化还原诱导微过氧化物酶-11构象变化的原位紫外和圆二色光谱电化学研究, In-situ UV and CD spectroelectrochemistry investigation of the electrochemical reduction reaction induced conformational transition of microperoxidase-11, 高等学校化学学报, 2006, 第 1 作者
（39） Didodecyldimethylammonium Bromide lipid bilayer-protected gold nanoparticles: synthesis, characterization and self-Assembly, Langmuir, 2006, 第 4 作者
（40） Conformational changes of beta-lactoglobulin induced by anionic phospholipid, Biophysical Chemistry, 2006, 第 3 作者
（41） In vitro study on the binding of neutral red to bovine serum albumin by molecular spectroscopy, Journal of Photochemistry and Photobiology A-Chemistry, 2006, 第 2 作者
（42） Assemble of poly (aniline–co–o -aminobenzenesulfonic acid) three-dimensional tubal net-works onto ITO electrode and its application for the direct electrochemistry and electrocatalytic behavior of cytochrome c, Electrochemistry Communications, 2006, 第 1 作者
（43） Surface-enhanced resonance Raman spectroscopy and spectroscopy study of redox-induced conformational equilibrium of cytochrome c adsorbed on DNA-modified metal electrode, Biosensors & Bioelectronics, 2006, 第 1 作者
（44） Effect of electrode surface microstructure on electron transfer induced conformation changes in cytochrome c monitored by in situ UV and CD spectroelectrochemistry., Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2005, 第 1 作者
（45） Attachment of gold nanoparticles to glassy carbon electrode and its application for the direct electrochemistry and electrocatalytic behavior of hemoglobin, Biosensors & Bioelectronics, 2005, 第 2 作者
（46） Attachment of gold nanoparticles to glassy carbon electrode and its application for the voltammetric resolution of ascorbic acid and dopamine, Journal of Electroanalytical Chemistry, 2005, 第 2 作者
（47） Syntheses of fully sulfonated polyaniline nano-networks and its application to the direct electrochemistry of cytochrome c, Biosensors & Bioelectronics, 2005, 第 2 作者
（48） Spectrometric and voltammetric investigation of interaction of neutral red with calf thymus DNA: pH effect, Biophysical Chemistry, 2005, 第 1 作者
（49） Effect of colloidal gold size on the conformational changes of adsorbed cytochrome c: probing by circular dichroism, UV-visible and infrared spectroscopy, Biomacromolecules, 2005, 第 1 作者
（50） A Colloidal Au monolayer modulates the conformation and orientation of a protein at the electrode/solution interface, ChemPhysChem, 2005, 第 1 作者
（51） Cytochrome c superstructure biocomposite nucleated by gold nanoparticle: Thermal stability and voltammetric behavior, Biomacromolecules, 2005, 第 1 作者
（52） Surface charge influence on the surface plasmon absorbance of electroactive thiol-protected gold nanoparticles, Langmuir, 2004, 第 3 作者
（53） pH-dependent conformation changes of ferricytochrome c induced by electrode surface microstructure, Biophysical Chemistry, 2004, 第 1 作者
（54） 利用奇异值分解最小二乘法（SVDLS）解析蛋白质的现场光谱电化学圆二色（CD）谱, Analyzing the in situ spectroelectrochemical circular dichroism (CD) spectra of protein by the method of singular value of decomposition and least squares (SVDLS), 计算机与应用化学, 2003, 第 2 作者
（55） One-step synthesis and size control of dendrimer-protected gold nanoparticles: a heat-treatment-based strategy, Macromolecular Rapid Communications, 2003, 第 2 作者
（56） 双核磺化酞菁钴在混合溶剂中聚集现象的光谱和电化学研究, Spectroscopy and electrochemistry studies on the aggregation of binuclear cobalt phthalocyaninehexasulfonate in mixed solutions, 光谱学与光谱分析, 2003, 第 2 作者
（57） Electrochemistry and electrocatalysis of binuclear cobalt phthalocyaninehexasulfonate-surfactant film modified electrode, Talanta, 2003, 第 1 作者
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Quantum Dots: Applications in Biology-Basics for the preparation of QDs and their interactions with living cells, Humana Press, 2014-08, 第 1 作者

   

（ 1 ） 纳米—生物相互作用的分析研究, 负责人, 国家任务, 2014-01--2016-12
（ 2 ） 吉林省纳米生物分析创新团队, 负责人, 地方任务, 2015-01--2017-12
（ 3 ） (青年基金)基于半导体负载的石墨烯纳米复合物协同治疗癌症, 参与, 地方任务, 2014-01--2016-12
（ 5 ） H2O2-激活的半导体纳米粒子用于成像分析介导的光热和光动力治疗癌症, 参与, 国家任务, 2016-01--2018-12

（1）纳米材料与细胞膜的相互作用及毒性机理研究   中国毒理学会第七次全国学术大会   姜秀娥，武 烈，王田田   2015-10-25
（2）Biodegradable PLA-mediated sustainable release nanocarrier for target drug delivery and mitigating the side-effects   第六届中国国际纳米科学技术会议   马志方，姜秀娥   2015-09-03
（3）Study the Interaction between Graphene Derivatives and Lipid Membrane by Surface-Enhanced Infrared Absorption (SEIRA) Spectroscopy   第十五届国际电分析化学学术会议   姜秀娥，武烈，王田田   2015-08-13
（4）表面增强红外光谱电化学研究细胞色素 c 与含心磷脂生物膜的相互作用   第十二届全国分析化学年会   曾丽，刘丽，姜秀娥   2015-05-08
（5）Confocal Microscopy and Surface-Enhanced FT-IR Spectroscopy Study the Toxic Mechanism of Quantum Dots in Red Blood Cells   第8届IUPAP国际生物物理大会   姜秀娥   2014-06-18
（6）A Facile One-pot Synthesis of Copper Sulfide-Decorated Reduced Graphene Oxide Composites and their applications in sensor and chemo-photothermal therapy   第五届中国国际纳米科学技术会议   姜秀娥   2013-09-05
（7）Application of Surface-enhanced FTIR Spectroelectrochemistry in Biological Membrance-related Interfacial Analysis   第十四届国际电分析化学学术会议   姜秀娥   2013-08-17
（8）配体对CdSe/ZnS 量子点与HAS相互作用的影响   第十一届全国分析化学年会   姜秀娥   2012-10-26
（9）Cellular Uptake of Nanoparticles: A Study Combining Confocal Microscopy with FTIR Spectroelectrochemistry   第六届纳米毒理学国际大会   姜秀娥   2012-09-04