081703-生物化工

生物分离材料制备、改性与应用

2005-09--2010-06   中国科学院过程工程研究所   生物化工博士
2001-08--2005-06   华东理工大学   生物工程学士以及英语学士

   

2016-07~2018-06,科技部中国生物技术发展中心, 借调
2013-10~2016-08,中国科学院过程工程研究所, 副研究员
2010-07~2013-09,中国科学院过程工程研究所, 助理研究员
2005-09~2010-06,中国科学院过程工程研究所, 生物化工博士
2001-08~2005-06,华东理工大学, 生物工程学士以及英语学士

2016-09-01-2017-12-30,中国科协主管《科学中国人》杂志社栏目负责人, 采编
2016-07-01-2018-07-01,科技部中国生物技术发展中心, 项目管理

生物过程工程

   

（1） 中国分析测试协会科学技术奖, 二等奖, 国家级, 2014

（ 1 ） 聚甲基丙烯酸缩水甘油酯类或其共聚物的亲水改性方法及改性所得材料, 2016, 第 2 作者, 专利号: 201610309058.3

（ 2 ） 一种聚苯乙烯类材料的亲水改性方法及其产品, 2015, 第 2 作者, 专利号: 201510671362.8

（ 3 ） 一种利用离子交换树脂对丁二酸发酵液进行脱色的方法, 2014, 第 1 作者, 专利号: 201110029752.7

（ 4 ） 一种连续结晶生物制造丁二酸的装置及方法, 2014, 第 1 作者, 专利号: 201110035318.X

（ 5 ） 一种基于生物脱硫的酸性硫酸盐有机废水综合处理装置及方法, 2014, 第 3 作者, 专利号: CN201110141078.1

（ 6 ） 一种基于全膜分离系统的丁二酸分离装置及方法, 2014, 第 3 作者, 专利号: CN201010574166.6

（ 7 ） 一种用于生产生物天然气的生物脱硫与二氧化碳回收耦合的方法和装置, 2014, 第 3 作者, 专利号: ZL 201110155482.4

（ 8 ） 一种聚苯乙烯类材料的亲水改性方法及其产品, 2014, 第 3 作者, 专利号: 201312130046130

（ 9 ） 一种生物脱硫处理反应器及生物脱硫处理系统和处理方法, 2013, 第 4 作者, 专利号: ZL 201010574170.2

（ 10 ） 一种具有硫酸盐还原功能的柠檬酸杆菌及其应用, 2012, 第 3 作者, 专利号: ZL 201110100429.4

   

（1） Enhanced binding by dextran-grafting to Protein A affinity chromatographic media, Journal of Separation Science, 2017, 第 4 作者
（2） Multi-layer dextran-decorated poly(glycidyl methacrylate)-co-divinyl benzene copolymer matrices enabling efficient protein chromatographic separation, Reactive & Functional Polymers, 2017, 通讯作者
（3） Efficient fabrication of high-capacity immobilized metal ion affinity chromatographic media: The role of the dextran-grafting process and its manipulation, Journal of Separation Science, 2016, 第 4 作者
（4） Functional hydrophilic polystyrene beads with uniformly size and high cross-linking degree facilitated rapid separation of exenatide, Journal of Chromatography B, 2016, 第 1 作者
（5） CO2 Biofixation of Actinobacillus succinogenes Through Novel Amine-Functionalized Polystyrene Microsphere Materials, Applied Biochemistry and Biotechnology, 2016, 通讯作者
（6） Preparation of a novel polymer monolith with high loading capacity by grafting block poly(PEGA-mPEGA) for high-efficiency solid phase synthesis, Reactive and Functional Polymers, 2015, 第 2 作者
（7） Preparation of PEGA grafted poly(chloromethylstyrene-co-ethylene glycol dimethacrylate) monolith for high-efficiency solid phase peptide synthesis under continuous flow techniques, Polymer, 2015, 第 2 作者
（8） Detailed exploration of structure formation of an epoxy-based monolith with three-dimensional bicontinuous structure, RSC Advances, 2015, 第 3 作者
（9） 聚二乙烯基苯微球介质制备及其在奥曲肽层析分离中的应用, 过程工程学报, 2015, 第 2 作者
（10） Cell-nanoparticle assembly fabricated for CO2 capture and in situ carbon conversion, Journal of CO2 Utilization, 2015, 第 1 作者
（11） Rapid octreotide separation from synthetic peptide crude mixtures by chromatography on poly(styrene-co-divinylbenzene)-based reversed phases, Separation and Purification Technology, 2015, 通讯作者
（12） Fine-tuning of ecaA and pepc gene expression increases succinic acid production in Escherichia coli, Appl Microbiol Biotechnol, 2015, 第 4 作者
（13） Preparation of water-in-oil emulsions using a hydrophobic polymer membrane with 3D bicontinuous skeleton structure, Journal of Membrane Science, 2015, 第 3 作者
（14） Improving the lactic acid production of Actinobacillus succinogenes by using a novel fermentation and separation integration system,  Process Biochemistry, 2014, 第 1 作者
（15） Preparation of Large-sized Highly Uniform Agarose Beads by Novel Rotating Membrane Emulsification, Journal of Membrane Science , 2014, 第 2 作者
（16） Hydrophilic modification gigaporous resins with poly(ethylenimine) for high-throughput proteins ion-exchange chromatography, Journal of Chromatography A, 2014, 第 2 作者
（17） Solvent Effect on Zeta Potential at an Aqueous/Oil Interface in Surfactant-Free Emulsion, Langmuir, 2014, 第 2 作者
（18） Effects of metal ions on the hydrolysis of bamboo biomass in 1-butyl-3-methylimidazolium chloride with dilute acid as catalyst, Bioresource Technology , 2014, 第 4 作者
（19） Efficient resveratrol production by immobilized beta-glucosidase on cross-linked chitosan microsphere modified by L-lysine, Journal of Molecular Catalysis B: Enzymatic, 2014, 通讯作者
（20） A novel gigaporous GSH affinity medium for high-speed affinity chromatography of GST-tagged proteins. , Protein Expression and Purification, 2014, 第 4 作者
（21） Ionic liquid pretreatment to increase succinic acid production from lignocellulosic biomass, Bioresource Technology, 2014, 第 3 作者
（22） Clarification of succinic acid fermentation broth by ultrafiltration in succinic acid biorefinery, Journal of Chemical Technology and Biotechnology, 2013, 第 2 作者
（23） Efficient decolorization and deproteinization using uniform polymer microspheres in the succinic acid biorefinery from bio-waste cotton (Gossypium hirsutum L.) stalks, Bioresource Technology, 2013, 第 1 作者
（24） In situ inhibitor (HCl) removal promoted heterogeneous Friedel-Crafts reaction of polystyrene microsphere with Lewis acids catalysts, Journal of Molecular Catalysis A: Chemical, 2013, 第 1 作者
（25） An insight into structure regulation of uniform polystyrene micro/nano-particles by porogen in premix membrane emulsification process, Journal of Membrane Science, 2013, 第 1 作者
（26） Enzymatic Hydrolysis and Succinic Acid Fermentation from Steam-Exploded Corn Stalk at High Solid Concentration by Recombinant Escherichia coli, Applied Biochemistry and Biotechnololy, 2013, 第 1 作者
（27） Bio-oil based biorefinery strategy for the production of succinic acid. , Biotechnology for Biofuels, 2013, 第 4 作者
（28） Clarification of succinic acid fermentation broth by ultrafiltration in bio-refinery of succinic acid,  Journal of Chemical Technology and Biotechnology, 2013, 第 2 作者
（29） In situ magnetization technique for synthesis of magnetic polymer microspheres. , Powder Technology, 2013, 第 4 作者
（30） Simultaneous Removal of Thiophene and Dibenzothiophene by Immobilized Pseudomonas delafieldii R-8 cells, Chinese Journal of Chemical Engineering, 2012, 第 2 作者
（31） Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM), Journal of Zhejiang University-Science B(Biomedicine & Biotechnology), 2012, 第 2 作者
（32） 国家生化工程技术研究中心(北京), 科学中国人, 2012, 第 1 作者
（33） Preparation of molecularly imprinted nanospheres by premix membrane emulsification technique. , Journal of Membrane Science, 2012, 第 2 作者
（34） Preparation of poly (ethylene glycol) acrylate grafted polystyrene resin for solid-phase peptide synthesis. , Reactive and Functional Polymers, 2012, 第 2 作者
（35） Covalently Coating Dextran on Macroporous Polyglycidyl Methacrylate Microsphere Enabled Rapid Protein Chromatographic Separation. , Materials Science and Engineering C-Materials, 2012, 第 2 作者
（36） Membrane fouling mechanism in ultrafiltration of succinic acid fermentation broth. , Bioresource Technology, 2012, 第 2 作者
（37） Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM), Zhejiang Univ Sci B (Biomed Biotechnol), 2012, 第 2 作者
（38） A novel up-flow inner-cycle anoxic bioreactor (UIAB) system for the treatment of sulfide wastewater from purification of biogas. , Water Science and Technology, 2012, 第 2 作者
（39） Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsorption system. , Biochemical Engineering Journal, 2011, 第 1 作者
（40） Enhancement of desulfurization performance of nickel-based adsorbents by hydrogen reduction pretreatment. , Catalysis Communications, 2011, 第 2 作者
（41） Efficient production of succinic acid from corn stalk hydrolysates by a recombinant Escherichia coli with ptsG mutation, Process Biochemistry, 2011, 第 2 作者
（42） One step recovery of succinic acid from fermentation broths by crystallization. , Separation and Purification Technology, 2011, 第 1 作者
（43） Efficient conversion of crop stalk wastes into succinic acid production by Actinobacillus succinogenes. , Bioresource Technology, 2010, 第 1 作者
（44） pH Neutralization while succinic acid adsorption onto anion-exchange resins. , Applied Biochemistry and Biotechnology, 2010, 第 1 作者
（45） Kinetic evaluation of products inhibition to succinic acid producers Escherichia coli NZN111, AFP111 BL21 and Actinobacillus succinogenes 130ZT. , The Journal of Microbiology, 2010, 第 1 作者
（46） Dual-phase fermentation enables Actinobacillus succinogenes 130ZT to be a potential role for high-level lactate production from the bioresource. , Bioresource Technology, 2010, 第 1 作者

（ 1 ） 耦合生化反应与分离的原位分离技术, in situ separtaion technology coupled bioreaction, 化学工业出版社, 2010-01, 第 1 作者
Microorganisms in Biorefineries, Springer, 2015-01, 第 1 作者
Production of 1,4-Diacids (Succinic, Fumaric, and Malic) from Biomass, Springer, 2017-06, 第 1 作者

   

（ 1 ） 细胞-纳米组装体的构筑及其对CO2捕获与原位碳转化, 负责人, 国家任务, 2013-01--2015-12
（ 2 ） 工业生物过程强化原理与方法, 负责人, 国家任务, 2013-01--2015-01
（ 3 ） 能够高效穿透粘液层和杯状细胞的口服多肽递送系统, 参与, 国家任务, 2013-01--2015-12
（ 4 ） 类病毒颗粒组合层析一体化介质的制备与性能研究, 参与, 国家任务, 2014-01--2016-12
（ 5 ） 原子转移自由基聚合法亲水修饰超大孔聚合物微球及其应用于生化分离, 参与, 研究所自主部署, 2012-01--2014-11

（1）干细胞及转化研究重点专项组织管理工作   国家重点研发计划干细胞及转化研究重点专项启动会   2017-12-13
（2）Preparation of hydrophilic modified uniformly sized polystyrene beadswith highly cross-linked degree and their application in chromatographyseparation    Qiang Li   2015-10-24
（3）葡聚糖接枝型高载量抗体介质的载量提升机制研究    2015年中国化工学会年会   朱凯   2015-10-17
（4）Combinatorial engineering of intergenic regions in operons to improve the succinic acid production in Escherichia coli   Dan Wang   2014-11-06
（5）Enhanced succinic acid production and magnesium utilization by overexpression of magnesium transport MgtA in Escherichia coli   Jing Wang   2014-05-17
（6）Rapid separation of peptide octreotide by chromatography on poly(styrene–co-divinylbenzene)-based reversed phases   Chenxu Zhang   2013-10-14
（7）Efficient decolorization and deproteinization using uniform polymer microspheres in the succinic acid biorefinery from bio-waste cotton stalks   Qiang Li   2013-06-16
（8）In situ mineral acid removal enhanced solid-phase Friedel-Crafts acylation on polystyrene microspheres   Qiang Li   2012-10-26