070703-海洋生物学
090801-水产养殖

海洋分子病毒学与功能基因组学、海洋环境微生物功能基因组学
鱼类细胞与分子免疫学

   

（ 1 ） 一株生产1,3-丙二醇的工程菌及其构建方法, 2013, 第 2 作者, 专利号: CN103146740A

（ 2 ） 一种红树林克雷伯氏菌及其在发酵法生产1,3-丙二醇中的应用, 2012, 第 2 作者, 专利号: ZL201210053231.X

（ 3 ） 一种石斑鱼虹彩病毒保护性抗原的筛选方法, 2011, 第 1 作者, 专利号: 201110110400.4

（ 4 ） 一种石斑鱼虹彩病毒囊膜蛋白的提取方法, 2011, 第 1 作者, 专利号: 201110110422.0

（ 5 ） 一种石斑鱼虹彩病毒灭活疫苗的制备方法, 2011, 第 2 作者, 专利号: 201110110399.5

   

（1） Generation and characterization of novel DNA aptamers against coat protein of grouper nervous necrosis virus(GNNV)with antiviral activities and delivery potential in grouper cells, Antiviral Research, 2016, 通讯作者
（2） JNK1 derived from orange-spotted grouper, Epinephelus coioides, involving in the evasion and infection of Singapore grouper iridovirus (SGIV), Frontiers in Microbiology, 2016, 通讯作者
（3） MHC polymorphism and disease resistance to Singapore grouper iridovirus (SGIV) in orange-spotted grouper, Epinephelus coioides., Science Bulletin, 2016, 通讯作者
（4） MHC class IIα polymorphisms and their association with resistance/susceptibility to Singapore grouper iridovirus (SGIV) in orange-spotted grouper, Epinephelus coioides, Aquculture, 2016, 通讯作者
（5） A tumour necrosis factor receptor-like protein encoded by Singapore grouper iridovirus modulates cell proliferation, apoptosis and viral replication, J Gen Virol, 2016, 通讯作者
（6） Characterization of cathepsin B gene from orange-spotted grouper, Epinephelus coioides involved in SGIV infection, Fish and Shellfish Immunology, 2014, 通讯作者
（7） Identification and characterization of Rab7 from orange-spotted grouper, Epinephelus coioides, Fish and Shellfish Immunology, 2014, 通讯作者
（8） Molecular cloning and expression of a C-type lectin-like protein from orange-spotted grouper Epinephelus coioides, Journal of Fish Biology, 2014, 通讯作者
（9） Characterization of LPS-induced TNFα factor (LITAF) from orange-spotted grouper, Epinephelus coioides, Fish and Shellfish Immunology, 2013, 通讯作者
（10） Molecular cloning, expression and functional analysis of ISG15 in orange-spotted grouper, Epinephelus coioides, Fish and Shellfish Immunology, 2013, 通讯作者
（11）  Identification and characterization of a tumor necrosis factor receptor like protein encoded by Singapore grouper iridovirus.,  Virus Research, 2013, 通讯作者
（12） Identification and characterization of TRP14, a thioredoxin-related protein of 14 kDa from orange-spotted grouper, Epinephelus coioides. , Fish and Shellfish Immunology, 2013, 通讯作者
（13） Molecular cloning, characterization of one key molecule of teleost innate immunity from orange-spotted grouper (Epinephelus coioides): Serum amyloid A. , Fish and Shellfish Immunology, 2013, 通讯作者
（14） Characterization of an envelope gene VP19 from Singapore grouper iridovirus, Virology Journal, 2013, 通讯作者
（15） miR-homoHSV of Singapore Grouper Iridovirus (SGIV) Inhibits Expression of the SGIV Pro-apoptotic Factor LITAF and Attenuates Cell Death, Plos One, 2013, 通讯作者
（16） An insulin-like growth factor homologue of Singapore grouper iridovirus modulates cell proliferation, apoptosis and enhances viral replication, Journal of General Virology, 2013, 通讯作者
（17） Medaka haploid embryonic stem cells are susceptible to Singapore grouper iridovirus as well as to other viruses of aquaculture fish species, Journal of General Virology, 2013, 通讯作者
（18）  Functional genomic studies on an immune- and antiviral-related gene of MyD88 in orange-spotted grouper, Epinephelus coioides, Chinese Science Bulletin, 2012, 通讯作者
（19） Grouper translationally controlled tumor protein prevents cell death and inhibits the replication of Singapore group er iridovirus (SGIV), Fish and Shellfish Immunology, 2012, 通讯作者
（20） Immunogenicity and protective effects of inactivated Singapore grouper iridovirus (SGIV) vaccines in orange-spotted grouper, Epinephelus coioides, Developmental and Comparative Immunology, 2012, 通讯作者
（21） Isolation and characterization of a thioredoxin domain-containing protein 12 from orange-spotted grouper,Epinephelus coioides, Fish and Shellfish Immunology, 2012, 通讯作者
（22） Selection and identification of Singapore grouper iridovirus vaccine candidate antigens using bioinformatics and DNA vaccination, Veterinary Immunology and Immunopathology, 2012, 通讯作者
（23） Cloning, characterization, and expression analysis of a thioredoxin from orange-spotted grouper (Epinephelus coioides), Developmental and Comparative Immunology, 2012, 通讯作者
（24） Molecular cloning and characterization of c-typ e lysozyme gene in orange-spotted groupe r,Epinephelus coioides, Fish and Shellfish Immunology, 2012, 通讯作者
（25） Singapore grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a cell type dependent fashion and evokes ERK signaling, Apoptosis, 2011, 通讯作者
（26） Roles of stress-activated protein kinases in the replication of Singapore grouper iridovirus and regulation of the inflammatory responses in grouper cells, J Gen Virol., 2011, 通讯作者
（27） Involvement of the mitogen-activated protein kinase pathway in soft-shelled turtle iridovirus-induced apoptosis, Apoptosis, 2011, 通讯作者
（28） Establishment of a cell line from the brain of grouper (Epinephelus akaara) for cytotoxicity testing and virus pathogenesis, Aquaculture , 2011, 通讯作者
（29） Gong J, Huang YH, Huang XH, Ouyang ZL, Qin QW. Establishment and Characterization of a new cell line derived from kidney of grouper (Epinephelus akaara) susceptible to Singapore grouper iridovirus (SGIV), Journal of fish disease, 2011, 通讯作者
（30） Zhou S, Wan Q, Huang Y, Huang X, Cao J, Ye L, Lim TK, Lin Q, Qin Q. Proteomic analysis of Singapore grouper iridovirus envelope proteins and characterization of a novel envelope protein VP088, Proteomics, 2011, 通讯作者
（31） Identification of a Novel Marine Fish Virus, Singapore Grouper Iridovirus-Encoded MicroRNAs Expressed in Grouper Cells by Solexa Sequencing, PLoS One, 2011, 通讯作者
（32） Differential profiles of gene expression in Singapore grouper iridovirus （SGIV） infected grouper, Epinephelus coioides revealed by suppression subtractive hybridization （SSH） and DNA microarray, Journal of Fish Biology, 2010, 通讯作者
（33） Establishment and characterization of a new marine fish cell line derived from red spotted grouper, Epinephelus akaara, Journal of Fish Biology, 2010, 通讯作者
（34） Nuclear-export-signal-dependent protein translocation of dUTPase encoded by Singapore grouper iridovirus.,  Arch Virol., 2010, 通讯作者
（35） Identification and characterization of a novel capsid protein encoded by Singapore grouper iridovirus ORF038L. , Arch Virol., 2010, 通讯作者
（36） Identification and characterization of Singapore grouper iridovirus (SGIV) ORF162L, an immediate-early gene involved in cell growth control and viral replication. , Virus Res., 2010, 通讯作者
（37） Molecular cloning, characterization and expression analysis of a C-type lectin (Ec-CTL) in orange-spotted grouper, Epinephelus coioides. , Fish and Shellfish Immunology, 2009, 通讯作者
（38） Characterization of Singapore grouper iridovirus (SGIV) ORF086R, a putative homolog of ICP18 involved in cell growth control and virus replication. , Arch Virol., 2009, 通讯作者
（39） Characterization of two grouper Epinephelus akaara cell lines: Application to studies of Singapore grouper iridovirus (SGIV) propagation and virus–host interaction. , Aquaculture, 2009, 通讯作者
（40） Complete sequence determination of a novel reptile iridovirus isolated from soft-shelled turtle and evolutionary analysis of Iridoviridae. , BMC Genomics, 2009, 通讯作者
（41）  Identification and characterization of a putative lipopolysaccharide-induced TNF-alpha factor (LITAF) homolog from Singapore grouper iridovirus. , Biochem Biophys Res Commun. , 2008, 通讯作者
（42） Rapid and sensitive detection of Singapore grouper iridovirus by loop-mediated isothermal amplification. , J Appl Microbiol. , 2008, 通讯作者
（43） Whole-genome transcriptional profiles of a novel marine fish iridovirus, Singapore grouper iridovirus (SGIV) in virus-infected grouper spleen cell cultures and in orange-spotted grouper, Epinephulus coioides. , Virology, 2008, 通讯作者
（44） Development of a sensitive and quantitative assay for spring viremia of carp virus based on real-time RT-PCR. , J Virol Methods, 2008, 通讯作者
（45） Characterization of complete genome sequence of the spring viremia of carp virus isolated from common carp (Cyprinus carpio) in China.,  Archives of Virology, 2007, 通讯作者
（46） Development of a SYBR green I Real-time PCR for quantitative detection of Vibro alginolyticus in seawater and sea food. , Journal of Applied Microbiology, 2007, 通讯作者

（ 1 ） 鱼类细胞培养理论与技术, Theory and technology of fish cell culture , 科学出版社, 2011-04, 第 2 作者

   

（ 1 ） 现代生态海洋农业科技创新技术试验与示范, 负责人, 中国科学院计划, 2011-01--2013-12
（ 2 ） 鱼类虹彩病毒病暴发和流行机制, 负责人, 国家任务, 2006-01--2011-12
（ 3 ） 水产保护学, 负责人, 国家任务, 2008-01--2011-12
（ 4 ） 石斑鱼宿主细胞感染虹彩病毒（SGIV）后的细胞凋亡机制, 负责人, 国家任务, 2010-01--2013-12
（ 5 ） 重要海水养殖动物病害防控的理论与技术, 负责人, 中国科学院计划, 2009-01--2011-12
（ 6 ） 南海特色海洋生物功能基因开发与利用, 负责人, 国家任务, 2012-01--2014-12
（ 7 ） 新型海洋微生物制品开发的关键技术研究与示范应用, 负责人, 国家任务, 2012-01--2015-12
（ 8 ） 重要海水养殖动物病害防控的理论与技术, 负责人, 中国科学院计划, 2011-01--2013-12
（ 9 ） 黑潮驱动下南海东北部生物多样性与生产力分布格局, 负责人, 国家任务, 2013-01--2017-12
（ 10 ） 在单病毒粒子水平研究石斑鱼虹彩病毒SGIV侵染宿主细胞的机制, 负责人, 国家任务, 2014-01--2018-12
（ 11 ） 鱼类虹彩病毒病爆发的细胞基础与分子机制, 负责人, 国家任务, 2012-01--2016-12