基本信息
常江  男  博导  中国科学院上海硅酸盐研究所
电子邮件: jchang@mail.sic.ac.cn
通信地址: 上海市定西路1295号
邮政编码: 200050

研究领域

   

招生信息

   
招生专业
080502-材料学
招生方向
生物陶瓷、有机/无机复合生物材料
生物材料的仿生制备及其物理化学过程研究

教育背景

1987-09--1991-06   德国达姆斯达特工业大学   博士
学历
   
学位
   

工作经历

   
工作简历
2000-12~现在, 中国科学院上海硅酸盐研究所, 研究员
1999-07~2000-11,美国强生公司组织损伤修复技术中心, 研究员
1997-07~1999-07,美国纽约大学医学院, 研究助理教授
1993-07~1997-06,新西兰奥克兰大学医学院, 研究员
1991-04~1993-06,德国卢卑克医科大学医学分子生物学研究所, 博士后研究员
1987-09~1991-06,德国达姆斯达特工业大学, 博士
社会兼职
   

教授课程

   

专利与奖励

   
奖励信息
(1) 美国生物医学工程协会的Fellow, 其他, 2015
(2) 英国皇家学会会士, 其他, 2014
(3) 第四届中国侨界贡献奖(创新人才), , 国家级, 2012
(4) 国际生物材料科学与工程学会联合会会士, , 其他, 2012
(5) 中国科学院朱李月华优秀教师奖, , 院级, 2012
(6) 全国归侨侨眷先进个人, , 国家级, 2009
(7) 第一届长宁区领军人才, , 市地级, 2007
(8) 可控性微结构多孔生物陶瓷作为组织工程支架的研制及应用, 二等奖, 省级, 2006
(9) 新西兰华人杰出贡献奖, , 其他, 1996
专利成果
( 1 ) 生物活性陶瓷材料及其制备方法, 2012, 第 2 作者, 专利号: 201210069971.2
( 2 ) 一种生物源人工小口径血管及其制备方法, 2011, 第 1 作者, 专利号: 201110165428.8
( 3 ) 硅酸钙前驱体水热制备羟基磷灰石粉体的方法, 2011, 第 1 作者, 专利号: 201110041186.1
( 4 ) 硬模板水热控制羟基磷灰石粉体形貌的方法, 2011, 第 1 作者, 专利号: 201110170339.2
( 5 ) 介孔生物活性玻璃和壳聚糖复合多孔止血材料及制备方法, 2010, 第 1 作者, 专利号: 201010525865.1
( 6 ) 含锶硅酸钙生物陶瓷及其制备方法和应用, 2013, 第 1 作者, 专利号: 201310439715.2
( 7 ) 一种新型白硅钙石生物活性涂层的制备方法及用途, 2012, 第 1 作者, 专利号: 201210529149.X
( 8 ) 一种新型的多功能介孔生物活性玻璃支架及其制备方法和用途, 2012, 第 2 作者, 专利号: 201210382838.2
( 9 ) 人工生物心脏瓣膜材料及制备方法和用途, 2013, 第 2 作者, 专利号: 201310571743.X
( 10 ) 一种医用植入体及其制备方法和用途, 2012, 第 1 作者, 专利号: 201210329792.8
( 11 ) 原位成型可注射生物活性复合水凝胶及其制备方法和应用, 2016, 第 1 作者, 专利号: 201610200187.9
( 12 ) 具有活性离子释放功能的天然高分子生物活性创伤修复材料及其制备方法, 2016, 第 1 作者, 专利号: 201610200187.9
( 13 ) 生物可降解镁基金属陶瓷复合材料及其制备方法和应用, 2015, 第 2 作者, 专利号: 201511009518.2
( 14 ) 一种抗溃散钙硅基复合骨水泥及其制备方法和应用, 2015, 第 1 作者, 专利号: 201510797255.X
( 15 ) 一种生物矿化层/光固化树脂复合材料以及制备方法和应用, 2015, 第 1 作者, 专利号: 201510791559.5
( 16 ) 一种温度敏感型皮肤创伤敷料及其制备方法和应用, 2015, 第 1 作者, 专利号: 201510373225.6
( 17 ) 具有诱导成骨功能的镁黄长石/PMMA复合骨水泥及其制备方法, 2014, 第 1 作者, 专利号: 201410541808.0

出版信息

   
发表论文
(1) A bifunctional biomaterial with photothermal effect for tumor therapy and bone regeneration, Advanced Functional Materials, 2016, 第 11 作者
(2) Bioglass promotes wound healing by affecting gap junction connexin 43 mediated endothelial cell behavior, Biomaterials, 2016, 第 11 作者
(3) Design of a thermosensitive bioglass/agarose–alginate composite hydrogel for chronic wound healing, Journal of Materials Chemistry B, 2015, 第 11 作者
(4) Mesoporous bioactive glass nanolayer-functionalized 3D-printed scaffolds for accelerating osteogenesis and angiogenesis, Nanoscale, 2015, 第 11 作者
(5) Hierachically micro-patterned nanofibrious scaffolds with nanosized bio-glass surface for accelerating wound healing, Nanoscale, 2015, 第 11 作者
(6) D printing of hollow struts-packed bioceramic scaffolds for bone regeneration, ACS Applied Materials & Interfaces, 2015, 第 11 作者
(7) Clinoenstatite coatings have high bonding strength, bioactive ion release, and osteoimmunomodulatory effects that enhance in vivo osseointegration, Biomaterials, 2015, 第 11 作者
(8) Stimulation of osteogenesis and angiogenesis of hBMSCs by delivering Si ions and functional drug from mesoporous silica nanospheres, Acta Biomaterialia, 2015, 第 11 作者
(9) Stimulation of osteogenesis and angiogenesis of hBMSCs by delivering Si ions and functional drug from mesoporous silica nanospheres, Acta Biomaterialia, 2015, 第 11 作者
(10) Procyanidins-crosslinked aortic elastin scaffolds with distinctive anti-calcification and biological properties, Acta Biomaterialia, 2015, 第 11 作者
(11) Novel tricalcium silicate/magnesium phosphate composite bone cement having high compressive strength, in vitro bioactivity and cytocompatibility, Acta Biomaterialia, 2015, 第 11 作者
(12) Novel Co-akermanite (Ca2CoSi2O7) bioceramics with activity to stimulate osteogenesis and angiogenesis, Journal of Materials Chemistry B, 2015, 第 11 作者
(13) Preparation of hierarchical enamel like structures from nano- to macro-scale regulated by inorganic templates derived from enamel, Journal of Materials Chemistry B, 2015, 第 11 作者
(14) Designing ordered micropatterned hydroxyapatite bioceramics to promote the growth and osteogenic differentiation of bone marrow stromal cells, Journal of Materials Chemistry B, 2015, 第 11 作者
(15) An anisotropically and heterogeneously aligned patterned electrospun scaffold with tailored mechanical property and improved bioactivity for vascular tissue engineering, ACS Appl Mater Interfaces, 2015, 第 11 作者
(16) The stimulation of osteogenic differentiation of mesenchymal stem cells and vascular endothelial growth factor secretion of endothelial cells by β-CaSiO3/β-Ca3(PO4)2 scaffolds, Journal of Biomedical Materials Research. Part A, 2014, 第 11 作者
(17) Tailoring Si-substitution level of Si-hydroxyapatite nanowires via regulating Si-content of calcium silicates as hydrothermal precursors, Ceramics International, 2014, 第 11 作者
(18) Collagen/wollastonite nanowire hybrid scaffolds promoting osteogenic differentiation and angiogenic factor expression of mesenchymal stem cells, Journal of Nanoscience and Nanotechnology, 2014, 第 11 作者
(19) Multilevel hierarchically ordered artificial biomineral, Small , 2014, 第 11 作者
(20) Silicate bioceramics enhanced vascularization and osteogenesis through stimulating interactions between endothelia cells and bone marrow stromal cells, Biomaterials, 2014, 第 11 作者
(21) Multidirectional effects of Sr, Mg and Si-containing bioceramic coatings with high bonding strength on inflammation, osteoclastogenesis and osteogenesis, ACS Applied Materials Interfaces, 2014, 第 11 作者
(22) Stimulation of osteogenic and angiogenic ability of cells on polymers by pulsed laser deposition of uniform akermanite-glass nanolayer, Acta Biomaterialia, 2014, 第 11 作者
(23) Mussel-inspired β-tricalcium phosphate bioceramics with Ca-P/polydopamine hybrid nanolayer: preparation, formation mechanism and improved cellular bioactivity, Acta Biomaterialia, 2014, 第 11 作者
(24) n vitro assessment of 3D-Plotted nagelschmidtite bioceramic scaffolds with varied macropore morphology, Acta Biomaterialia, 2014, 第 11 作者
(25) Nano-sized mesporous bioactive glass/poly (latic-co-glycolic acid) composite-coated CaSiO3 scaffolds with multifunctional properties for bone tissue engineering, BioMed Research International, 2014, 第 11 作者
(26) Bioactive bredigite coating with improved bonding strength, rapid apatite mineralization and excellent cytocompatibility, Journal of Biomaterials Applications, 2014, 第 11 作者
(27) Tailoring the Nanostructured Surfaces of Hydroxya patite Bioceramics to Promote Protein Adsorption, Osteoblast Growth, and Osteogenic Differentiation,  ACS Applied Materials Interfaces, 2013, 第 11 作者
(28) Enhanced osteoporotic bone regeneration by strontium-substituted calcium silicate bioactive ceramics, Biomaterials , 2013, 第 11 作者
(29) Delivery of dimethyloxallyl glycine in mesoporous bioactive glass scaffolds to improve angiogenesis and osteogenesis of human bone marrow stromal cells, Acta Biomaterialia, 2013, 第 11 作者
(30) The calcium silicate/alginate composite: preparation and evaluation of its behavior as bioactive injectable hydrogels, Acta Biomaterialia, 2013, 第 11 作者
(31) Enhanced osteogenesis through nano-structured surface design of macroporous hydroxyapatite bioceramic scaffolds via activation of ERK and p38 MAPK signaling pathways, Journal of Materials Chemistry B, 2013, 第 11 作者
(32) Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity, Biomaterials, 2013, 第 11 作者
(33) Functional mesoporous bioactive glass nanospheres: synthesis, apatite mineralization, controllable delivery of doxorubicin and inhibitory effect on bone cancer cells, Journal of Materials Chemistry B, 2013, 第 11 作者
(34) Nagelschmidtite bioceramics with osteostimulation property: material chemistry activating osteogenic genes and WNT signalling pathway of human bone marrow stromal cells, Journal of Materials Chemistry B, 2013, 第 11 作者
(35) Containerless processing for preparation of akermanite bioceramic spheres with homogenous structure, tailored bioactivity and degradation, Journal of Materials Chemistry B, 2013, 第 11 作者
(36) A brief review of bioactive silicate ceramics, Biomedical Materials, 2013, 第 11 作者
(37) Preparation, characterization and in vitro bioactivity of nagelschmidtite bioceramics, Journal of the American Ceramic Society, 2013, 第 3 作者
(38) Facile fabrication of nanorod-assembled fluorine-substituted hydroxyapatite (FHA) microspheres, Chemistry–An Asian Journal, 2013, 第 11 作者
(39) Osteogenesis and angiogenesis induced by porous b-CaSiO3/PDLGA compositescaffold via activation of AMPK/ERK1/2 and PI3K/Akt pathways, Biomaterials, 2013, 第 11 作者
(40) Stimulation of proangiogenesis by calcium silicate bioactive ceramic,  Acta Biomaterilia, 2013, 第 11 作者
(41) 硅酸盐生物活性陶瓷用于骨组织修复及再生的研究, 无机材料学报, 2013, 第 11 作者
(42) The effect of plaster (CaSO4?1/2H2O) on the compressive strength, self-setting property and in vitro bioactivity of silicate-based bone cement, Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2013, 第 11 作者
(43) Controlled drug release from polymer matrix by patterned electrospun nanofibers with controllable hydrophobicity, J Materials Chemistry B, 2013, 第 11 作者
(44) Electrospun Poly(l-lactide) Fiber with Ginsenoside Rg3 for Inhibiting Scar Hyperplasia of Skin, PLoS ONE, 2013, 第 11 作者
(45) Fabrication of patterned PDLLA/PCL composite scaffold by electrospinning, Journal of Applied Polymer Science, 2013, 第 11 作者
(46)  Strontium substituted hydroxyapatite porous microspheres: surfactant-free hydrothermal synthesis, enhanced biological response and sustained drug release, Chemical Engineering Journal, 2013, 第 11 作者
(47) Hollow magnetic hydroxyapatite microspheres with hierarchically mesoporous microstructure for pH –responsive drug delivery, CrystEngComm, 2013, 第 11 作者
(48) Stimulatory effects of the ionic products from Ca-Mg-Si bioceramics on both osteogenesis and angiogenesis in vitro, Acta Biomaterialia, 2013, 第 11 作者
(49) Bioactive silicate materials stimulate angiogenesis in fibroblast and endothelial cell co-culture system through paracrine effect,  Acta Biomaterialia., 2013, 第 11 作者
(50) Silicate bioceramics induce angiogenesis during bone regeneration, Acta Biomaterials, 2012, 第 11 作者
(51) The enhancement of bone regeneration by the combination of osteoconductivity and osteostimulation using β-CaSiO3/β-Ca3(PO4)2 composite bioceramics, Acta Biomaterialia, 2012, 第 11 作者
(52) Preparation and characterization of Sr hardystonite Sr2ZnSi2O7 for bone repair applications, Materials Science Engineering C, 2012, 第 11 作者
(53) In Vitro Degradation Behaviour and Bioactivity of Magnesium-Bioglass Composites for Orthopeadic Applications, Journal of Biomedical Materials Research B, 2012, 第 11 作者
(54) Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering, Biomaterials, 2012, 第 11 作者
(55) Dual drug release from electrospun poly(lactic-co-glycolic acid)/mesoporous silica nanoparticles composite mats with distinct release profiles, Acta Biomaterialia, 2012, 第 11 作者
(56) Study on Gentamicin Loading and Release from Mesoporous Bioactive Glasses (MBGs) with Different Shapes, Chemical Composition and Surface Property, Journal of Biomaterials and Tissue Engineering, 2012, 第 11 作者
(57) Effect of tricalcium silicate on the proliferation and odontogenic differentiation of human dental pulp cells, Journal of Endodont, 2011, 第 11 作者
(58) Proliferation and osteogenic differentiation of human periodontalligament cells on akermanite and beta-TCP bioceramics, European Cells Materials, 2011, 第 11 作者
(59) Ionic products from akermanite dissolution stimulate osteogenic differentiation of human adipose-derived stem cells via activation of ERK pathway, Biomaterials, 2011, 第 11 作者
(60) Mussel-inspired porous SiO2 scaffolds with improved mineralization and cytocompatibility for drug delivery and bone tissue engineering, Journal of Materials Chemistry, 2011, 第 3 作者
(61) Multifunctional magnetic mesoporous bioactive glass scaffolds with hierarchical pore structure, Acta Biomaterialia, 2011, 第 11 作者
(62) In situ preparation and protein delivery of silicate-alginate composite microspheres with core-shell structure, Journal of the Royal Society Interface, 2011, 第 11 作者
(63) Biomimetic hydroxyapatite porous microspheres with co-substituted essential trace elements:Surfactant-free hydrothermal synthesis,enhanced degradation and drug release,  Journal of Materials Chemistry, 2011, 第 11 作者
(64) Hierarchically structured nanocrystalline hydroxyapatite assembled hollow fibers as a promising protein delivery system, Chemical Communications, 2011, 第 11 作者
(65) Synthesis of the Element-substituted Hydroxyapatite with Controllable Morphologies and Chemical Compositions using Calcium Silicate as Precursor, CrystEngComm, 2011, 第 11 作者
(66) Modulation of Hydroxyapatite Crystal formed from Alpha-Tricalcium Phosphate by Surfactant-free Hydrothermal Exchange, CrystEngComm, 2011, 第 11 作者
(67) Facile Synthesis of Hydroxyapatite Nanoparticles, Nanowires and Hollow Nano-structured Microspheres using Similar Structured Hard-precursors, Nanoscale, 2011, 第 11 作者
(68) Polymer nanocomposites with controllable distribution and arrangement of inorganic nanocomponents, Nanoscale, 2011, 第 11 作者
(69) Physicochemical Properties and Biocompatibility of Tricalcium and Dicalcium Silicate Composite Cements after Hydration , International Journal of Applied Ceramic Technology, 2011, 第 11 作者
(70) Evaluation of an osteostimulative putty in the sheep spine, Journal of Materials Science: Materials in Medicine, 2011, 第 11 作者
(71) In vitro remineralization of human dental enamel by bioactive glasses, Journal of Materials Science: Materials in Medicine, 2011, 第 11 作者
(72) Biomedical Materials, Bulletin of the Chinese Academy of Sciences, 2011, 第 1 作者
(73) Effect of tricalcium aluminate on the properties of tricalcium silicate-tricalcium aluminate mixtures: setting time, mechanical strength and biocompatibility, International Endodontic Journal, 2011, 第 11 作者
(74) Fabrication and Characterization of Hydroxyapatite/Wollastonite Composite Bioceramics with controllable properties for hard tissue repair, of the American Ceramic Society, 2011, 第 11 作者
(75) Preparation and characterization of clinoenstatite bioceramics, Journal of the American ceramics Society, 2011, 第 11 作者
(76) Tricalcium silicate induced mineralization for occlusion of dentinal tubules, Australian Dental Journal, 2011, 第 11 作者
(77) Antibacterial activity of silicate bioceramics, Journal of Wuhan University of Technology-Mater.Sci.Ed, 2011, 第 11 作者
(78) The influences of poly(lactic-co-glycolic acid)(PLGA) coating on the biodegradability, bioactivity, and biocompatibility of calcium silicate bioceramics, Journal of Materials Science: Materials in Medicine, 2011, 第 11 作者
(79) Improvement of mechanical properties of macroporous b-tricalcium phosphate bioceramic scaffolds with uniform and interconnected pore structures, Ceramics International, 2011, 第 11 作者
(80) Study on the effect of inorganic salts on the alignment of electrospun fiber, Journal of Applied Polymer Science, 2011, 第 11 作者
(81) Evaluation of host inflammatory responses of β- tricalcium phosphate bioceramics caused by calcium pyrophosphate impurity using a subcutaneous model., Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2011, 第 11 作者
(82) Synthesis of well-ordered mesoporous 58S (M58S) bioactive glass by a simple method,  International Journal of Applied Ceramic Technology, 2011, 第 11 作者
(83) 介孔生物活性玻璃/脱钙骨复合支架的制备及性能研究, 无机材料学报, 2011, 第 11 作者
(84) 介孔生物活性玻璃装载和释放抗癌药物表阿霉素的研究, 无机材料学报, 2011, 第 11 作者
(85) Quercetin crosslinked porcine heart valve matrix: mechanical property, stability, anti-calcification and cytocompatibility, Acta Biomaterialia, 2010, 第 11 作者
(86) (87) 
发表著作
( 1 ) 生物活性无机材料在骨再生和药物释放中的应用, Advanced bioactive inorganic materials for bone regeneration and drug delivery, CRC Press and Taylor Francis, 2013-01, 第 2 作者

科研活动

   
科研项目
( 1 ) 硬组织生物活性材料与宿主局部微环境的相互作用以及在组织再生中的转归, 主持, 国家级, 2012-01--2016-12
( 2 ) 新型可降解生物活性骨内固定复合材料研究, 主持, 部委级, 2012-01--2015-12
( 3 ) 用于修复骨质疏松骨缺损的新型掺锶硅酸钙材料的研究, 主持, 国家级, 2011-01--2013-12
( 4 ) 骨替代生物材料的免疫反应, 主持, 部委级, 2015-01--2016-12
( 5 ) 颌骨组织“仿生理性”再生的调控及其机制研究, 参与, 国家级, 2015-01--2019-12
( 6 ) 生物材料化学信号、微纳米结构及力学特性对非骨组织再生诱导作用及其机制研究, 主持, 国家级, 2016-07--2020-12
( 7 ) 生物材料化学信号对组织诱导的作用, 主持, 国家级, 2016-07--2020-12
参与会议
(1)Design of bioactive materials for tissue regeneration   2015中国生物材料大会   2015-11-21
(2)Bioactive materials for bone tissue engineering   2015-11-05
(3)Bioactive ceramics for enhanced tissue regeneration    2015-10-27
(4)Study on injectable bioactive hydrogels for tissue regeneration    中国材料大会   2015-07-10
(5)Study on Calcium Silicate/Magnesium Phosphate Composite Bone Cement   2015-05-18
(6)Study on injectable bioactive hydrogels for tissue regeneration   2015-05-06
(7)Design of bioactive materials for tissue regeneration   2015-04-07
(8)生物活性陶瓷材料的设计及在骨修复/骨组织工程中的应用   2013中国生物材料年会   常江   2013-12-20
(9)Design of bioactive ceramics for enhanced bone regeneration   Jiang Chang   2013-12-04
(10)Study on bioactive ceramics for bone tissue engineering   Jiang Chang    2013-11-22
(11)用于硬组织修复的生物活性陶瓷/高分子复合材料研究   第十四届全国生物材料大会   常江   2013-09-27
(12)Bioactive ceramics stimulating osteogenic differentiation of stem cells, angiogenesis and bone regeneration   Jiang Chang   2013-09-16
(13) Silicates: A new generation of bioceramics for tissue regeneration!    Jiang Chang   2013-06-26
(14)Stimulation of osteogenesis and angiogenesis by bioceramics   Jiang Chang   2013-06-11
(15)Study on injectable silicates/alginate composite hydrogels   Jiang Chang   2013-04-08
(16)Bioceramics with bioactive composition and nano-structure for bone regeneration   第12届亚洲生物陶瓷会   Jiang Chang   2012-11-20
(17)Biomaterials with bioactive composition and nano-structure for tissue regeneration   Jiang Chang   2012-09-19
(18)Mesoporous silica and bioactive glasses for drug delivery and Tissue Engieering   Jiang Chang   2012-06-01
(19)Study on biomaterials with osteogenic and angiogenic properties   Jiang Chang   2011-12-18
(20)Study on silicate bioceramics   Jiang Chang   2011-11-30
(21)Biomaterials with bioactive composition and nano-structure for tissue regeneration   国际亚洲材料大会(IUMRS-ICA)   Jiang Chang   2011-09-19
(22)生物活性医用敷料的研究与临床应用   2011中国国际医用敷料大会   常江   2011-08-08
(23)Study on biomaterials with osteogenic and angiogenic properties   Jiang Chang   2011-05-29
(24)Modulation of Hydroxyapatite Crystal formed from Alpha-Tricalcium Phosphate by Surfactant-free Hydrothermal Exchange   Jiang Chang   2011-05-04
(25)Fabrication of nano structured biomaterials   Jiang Chang   2011-04-11

合作情况

   
项目协作单位
   

指导学生