General
苗龙 男 汉族 博导 生物物理研究所
Email: lmiao@moon.ibp.ac.cn
Telephone: 010-64888425
Address: 北京市朝阳区大屯路15号
Postcode: 100101

Research Areas

   

Education

1999 Ph.D. College of Biological Science, China Agricultural University

1994 B.S. Department of Agronomy, Inner Mongolian Agricultural University

Experience

2007-present Professor and Principal Investigator
 The Institute of Biophysics
Chinese Academy of Sciences

2003-2006 Research Assistant
Department of Biological Science
Florida State University

2001-2003 Postdoctoral fellow
Department of Biological Science
Florida State University
Advisor: Dr. Thomas M Roberts

1999-2000 Postdoctoral fellow
Division of Biological Sciences
University of California, Davis
Advisor: Dr. William J Lucas

1994-1999 Doctoral
College of Biological Science
China Agricultural University
Advisor: Professor Xue-Chen Wang
Teaching Experience
1996 – 1997 Teaching assistant for computer lab
China Agricultural University

1996 Directed undergraduate research
China Agricultural University

1995 Teaching assistant for plant physiology lab
China Agricultural University
Work Experience
   

Honors & Distinctions

2014 “Distinguished Young Scholar” from National Science Foundation of China
2009 Biochemical Journal Young Investigator Award

2007 Chinese Academy of Sciences: Hundred Talents Award

2004 AAAS/Science: Program for Excellence in Science Award

2004 3rd International Conference on Electron Tomography Travel Award for Young Investigator
1999 Excellent Thesis, China Agricultural University
1996 Graduate School Outstanding Student Award in Recognition of Progress in Research, China Agricultural University

1996 Honor Student, China Agricultural University

Publications

   
Papers
 1. Liu Z , Wang B , He R , Zhao Y , and Miao L. (2014) Calcium signaling and the MAPK cascade are required for sperm activation in Caenorhabditis elegans. Biochimica et biophysica acta 1843: 299-308.
2. Ma X , Zhu Y , Li C , Xue P , Zhao Y , Chen S , Yang F , and Miao L. (2014) Characterisation of Caenorhabditis elegans sperm transcriptome and proteome. BMC genomics 15: 168.
3. Chen D , Jian Y , Liu X , Zhang Y , Liang J , Qi X , Du H , Zou W , Chen L., Chai Y , et al. (2013) Clathrin and AP2 are required for phagocytic receptor-mediated apoptotic cell clearance in Caenorhabditis elegans. PLoS Genet 9: e1003517.
4. Liu Z , Chen L , Shang Y , Huang P , and Miao L. (2013) The micronutrient element zinc modulates sperm activation through the SPE-8 pathway in Caenorhabditis elegans. Development 140:2103-2107.
5. Huang P , Ma X , Zhao Y , and Miao L. (2013) The C. elegans homolog of RBBP6 (RBPL-1) regulates fertility through controlling cell proliferation in the germline and nutrient synthesis in the intestine. PloS one: e58736.
6. Shang Y , Chen L , Liu Z , Wang X , Ma X , and Miao L. (2013) Cytosolic Ca(2+) as a multifunctional modulator is required for spermiogenesis in Ascaris suum. Protein Cell 4:456-466.
7. Ma X , Zhao Y , Sun W , Shimabukuro K , and Miao L. (2012) Transformation: how do nematode sperm become activated and crawl? Protein Cell 3:755-761.
8. Dou J , Chen L , Hu Y , and Miao L. (2012). Cholesterol and the biosynthesis of glycosphingolipids are required for sperm activation in Caenorhabditis elegans. Biochimica et biophysica acta 1821:934-942.
9. Ma X , Zhao Y , Sun W , Shimabukuro K , and Miao L. (2012) Transformation: how do nematode sperm become activated and crawl? Protein Cell 3: 755-761.
10. Ma, X., Zhao, Y., Sun, W., Shimabukuro, K., and Miao, L. (2012). Transformation: how do nematode sperm become activated and crawl? Protein Cell 3, 755-761. 
11. Dou J, Chen L, Hu Y, Miao L. (2012) Cholesterol and the biosynthesis of sphingolipids are required for sperm activation in Caenorhabditis elegans. Biochim Biophys Acta [Epub ahead of print]
12. Zhao Y, Sun W, Zhang P, Chi H, Zhang M, Song C, Ma X, Shang Y, Wang B, Hu Y, Hao Z, Hühmer A, Meng, F, L'Hernault S, He S, Dong M, Miao L. (2012) Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin). PNAS 109: 1542–1547
13. Ma X, Zhu Y, Li C, Shang Y, Meng F, Chen S, Miao L. (2011) Comparative transcriptome sequencing of Germline and Somatic Tissues of the Ascaris suum Gonad. BMC Genomics 12:481
14. Chen D, Xiao D, Zhang K, Wang B, Gao Z, Jian Y, Qi X, Sun J, Miao L, Yang C. (2010) Retromer Sorting Complex Regulates Apoptotic Cell Clearance by Phagocytic Receptor Recycling. Science 327: 1261-1264
15. Zhang Y, Yan L, Zhou Z, Yang P, Tian E, Zhang K, Zhao Y, Li Z, Song B, Han J, Miao L,Zhang H. (2009) SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans. Cell 136: 308–321
16. Miao L, Vanderlinde O, Liu J, Grant RP, Wouterse A, Philipse A, Stewart M, Roberts TM. (2008) The role of filament packing dynamics in powering amoeboid cell motility. PNAS 105: 5390-5395
17. Wang B, Liu Z, Miao L. (2008) Recent Advances in the study of spermatogenesis and fertilization in Caenorhabditis elegans. Hereditas(Beijing) 30:677-686(invited review in Chinese)
18. Miao L. (2007) Recent progresses on the cellular motility, cell migration and cytoskeleton. Acta Biophysica Sinica 23:281-289 (invited review in Chinese)
19. Miao L, Yi K, Mackey JM, Roberts TM. (2007) Reconstitution in vitro of MSP-based filopodium extension in nematode sperm. Cell Motility and Cytoskeleton. 64:235-247.
20. Wolgemuth C, Miao L, Vanderlinde O, Roberts TM, Oster G. (2005) MSP dynamics drives nematode sperm locomotion. Biophysical Journal 88: 2462-2471.
21. Miao L, Vanderlinde O, Stewart M, Roberts TM. (2003) Retraction in amoeboid cell motility powered by cytoskeletal dynamics. Science 302: 1405-1407.

Patents
   

Students

已指导学生

刘志宇  博士研究生  071009-细胞生物学  

尚云龙  博士研究生  071009-细胞生物学  

黄平  博士研究生  071009-细胞生物学  

胡攸乔  博士研究生  071009-细胞生物学  

现指导学生

孙维  博士研究生  071009-细胞生物学  

林婷婷  博士研究生  071009-细胞生物学  

王秋实  博士研究生  071009-细胞生物学  

袁志恒  博士研究生  071009-细胞生物学  

王鹏  硕士研究生  071009-细胞生物学  

杜宝臣  博士研究生  071009-细胞生物学  

Research Interests

   

Conferences

   

Collaboration