General
Prof. Dr. Yonghong Liu
CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, No. 164 West Xingang Road, Guangzhou 510301, China.
Tel/FAX: 0086-20-89023244 
Email: yonghongliu@scsio.ac.cn 

Brief CurriculumVitae of Dr. Yonghong Liu:
Dr. Yonghong Liu received a PhD degree from the Pusan National University, Busan, Korea. He undertook postdoctoral research at Osaka University, Osaka, Japan and the New University of Lisbon, Lisbon, Portugal, before returning to China to take a position as a senior scientist in 2006 at the South China Sea Institute of Oceanology, Chinese Academy of Sciences. Currently, he is working as vice-director of Guangdong Key Laboratory of Marine Materia Medica. He has authored more than 160 peer reviewed articles (including Natural Product Reports, Food Chemistry, Tetrahedron, Phytochemistry, Journal of Natural Products, Planta Medica, Journal of Ethnopharmacology, Helvetica Chimica Acta, Chemistry & Biodiversity, Organic & Biomolecular Chemistry, Bioorganic Medicinal Chemistry, European Journal of Organic Chemistry, etc.84 SCI Journals), edited 8 books and monographs (in English), served as editorial board member of 11 international Journal (Natural products research, SCI) , awarded 3 national and provincial prizes, and held 11 issued patents. He is reviewer of several International academic Journals: Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Process Biochemistry, Molecules, Journal of Ethnopharmacology, and ACS publications: Such as Journal of Natural Products, Journal of Agriculture and Food Chemistry, Journal of Organic Chemistry, etc.  He engaged in discovery of new natural products lead structure with bioactivity, he has focus on the isolation, structural elucidation, synthesis of biologically-active secondary metabolites from marine invertebrates and medicinal plants and their endosymbionts, to develop anti-inflammatory, anti anti-rheumatic, and antihyptensive effects new drugs.

Research Areas

1. Bioactivities constituents of tropical marine invertebrates and their symbiotic microorganisms
The important area of research emphasis is the study of marine natural products, biochemicals produced by tropical marine invertebrates and their symbiotic microorganisms, which may have pharmaceutical applications for human health.
Investigations carried out at the Lab are invoved in collecting and identifying marine invertebrates (such as sponge, sea stars), identifying, screening and fermenting the microorganisms that produce potentially interesting natural products, extracting, isolating and identifying those chemicals from marine invertebrates or microorganisms, and screening for their effectiveness as possible pharmaceuticals.
2.Marine chemical ecology
Chemical substances play an important role in the interaction between all living organisms and their environment. The research that considers the impact of naturally occurring substances in the interaction between organisms is called chemical ecology. Research in chemical ecology in marine environments is still in the beginning of its exploitation and it is reasonable to assume that it has a great potential. Settlement of larvae of other benthic organisms may threaten the survival of individuals of benthic invertebrates. Therefore, benthic invertebrates have developed various defense systems against biofouling in the course of evolution, among which chemical defense is prominent. On the other hand, benthic organisms often cause economic problems by settling on ships’ hulls, cooling systems of power stations, aquaculture cages, and other submersible structures. Organotin compounds including tributyltin (TBT) and tributyltin oxide (TBTO) were widely used for controlling these sessile organisms until recently, when they were found to be toxic to many marine organisms. Therefore, “environmentally friendly” antifoulants need to be developed urgently. We are trying to study the nontoxic antifouling targeted chemical defence substances from marine invertebrates (eg. sponges).
Investigations carried out at the Lab are invoved in isolating and identifying the chemical defence substances guided by antifouling activities, studying the structural modifications and structure-activity relationships.
3. Synthesis of biologically-active secondary metabolites from marine invertebrates.

Education

Ph. D. August, 2002. Major: Marine Natural products Chemistry, College of Pharmacy, Pusan Natinal University, Pusan, Korea.
M. S. in Phytochemistry, 1999. Graduate School, Changchun College of Traditional Chinese Medicine, Chanchun, China.
B. S. in Traditional Chinese Medicine, 1996. Department of Traditional Chinese Pharmacology, Changchun College of Traditional Chinese Medicine, Chanchun, China.

Experience

Ph. D. August, 2002. Major: Marine Natural products Chemistry, College of Pharmacy, Pusan Natinal University, Pusan, Korea.
M. S. in Phytochemistry, 1999. Graduate School, Changchun College of Traditional Chinese Medicine, Chanchun, China.
B. S. in Traditional Chinese Medicine, 1996. Department of Traditional Chinese Pharmacology, Changchun College of Traditional Chinese Medicine, Chanchun, China.
Work Experience
South China Sea Institute of Oceanology, CAS (January, 2006–) Professor, Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences.

New University of Lisbon (April 2004 –December 2005) Postdoctoral Research Associate, Department of Chemistry, Faculty of Sciences and Technology.
Osaka University (April, 2003 - March 2004 ) Postdoctoral Research Associate, Graduate School of Pharmaceutical Sciences.
Pusan National University (September, 2002-March, 2003): Graduate Research Assistant: College of Pharmacy.

Honors & Distinctions

1. PhD scholarship for study abroad awarded by the Ministry of Korean Sciences and Technology (1999-2002).
2. Postdoctorship of the Ministry of Korean Maritime Affairs and Fisheries $16,000. 2002-2003.
3. Postdoctorship of Japan Science and Technology Corporation, $20,000, 2003-2004.
4. Postdoctorship of Portugal Foundation of Science and Technology, $17950, 2004-2005.
5. The Grant of the K. C. Wong Education Foundation, Hong Kong, 2005-2006, $2000.
6. The Using Technologys of Bioactive Metabolites from Tropical Marine Organisms, 2007 National Scientific and Technological Progress Award, Second Class (Ranking 12).
7. Research on Ecological Environment and Biological Resource of Sanya Bay and Its Adjacent Sea Area, 2010 Hainan Province Scientific and Technological Progress First Prize (Ranking 14).
8. Saururus chinensis Etc. Five Chinese Medicinal Materials’ Medicinal Efficacy Material Base and Pharmaceutical Preparation “Xiaoganxian”, 2011 Jilin Province Scientific and Technological Progress Award, Second Class (Ranking 3).

Publications

Book
1. Dayou Liu, Yonghong Liu, etc. “Practical Beauty Prescription of Traditional Chinese Medicine”. People Public Heath Publishing House, in 1998.
2. Yonghong Liu, etc《China Marine Herbal》, The Chemistry Of Molluscs
Book chapter
3. Liu Y, Zhang S, Jung J, Xu T. Bioactive furanosesterterpenoids from marine sponge,《Topics in Heterocyclic Chemistry》book chapter,Springer publisher, 2007, pp231-258.
4. Liu Y. Alisma orientale, a common Traditional Chinese Medicine as a diuretic agent,《Encyclopedia of Medicinal Plant》book chapter, 2009, Stadium Pree LLC, U.S.A. pp427-445.
5 Hu J, Liu Y. Bioactive metabolites from seaweeds,《Handbook of Macroalgae: Biotechnology and Applied Phycology》book chapter,Wiley-Blackwell publisher
2011, p262-284.
(6) Yang B, Liu Y. Chemical Properties of Marine Cosmeoceuticals, 《Marine Cosmeceuticals: Latest Trends and Prospects》book chapter,CRC-Taylor & Francis publishers 2011, p11-38.
(7) Liu Y.《Marine Pharmacognosy: Trends and Applications》book chapter, Editor:Se-Kwon Kim,Taylor & Francis CRC Press
Papers

  1. Wang L, Yang B, Lin X, Zhou X,Liu Y*. Sesterterpenoids,Natural Product Reports, 2013, 30, 455-473 (IF11.876).
  2. Liu Y*,Wang L,Jung J, Zhang S.Sesterterpenoids.Natural Product Reports,2007,24(6), 1401-1429 (IF 11.876).

  3. Liu Y*, Zhang S, Abreu P. Heterocyclic terpenes: linear furano-and pyrroloterpenoids.Natural Product Reports, 2006, 23(4),630-651 (IF11.876).

  4. Wang J, Cong Z, Huang X,Hou C, Chen W, Tu Z, Huang D,Liu Y*.Soliseptide A,acyclichexapeptidepossessingpiperazicacidgroups fromStreptomyces solisilvaeHNM30702.Organic Letters, 2018,20,1371-1374 (IF6.555).

  5. ChenS,Wang J ,Lin X ,Zhao B ,Wei X ,Li G ,Kaliaperumal K ,Liao S ,Yang B ,Zhou X ,Liu J ,Xu S,*Liu Y*. Chrysamides A-C, three dimeric nitrophenyltrans-epoxyamides produced by the deep-sea-derived fungusPenicillium chrysogenumSCSIO41001.Organic Letters, 2016, 18, 3650-3653 (IF6.5555).

  6. Wang J, Wei X, Qin X, Lin X, Zhou X, Liao S, Yang B, Liu J, Tu Z, Liu Y*.Arthpyrones A–C,pyridone alkaloids from a sponge-derived fungusArthrinium arundinis ZSDS1-F3.Organic Letters, 2015, 17, 656-659 (IF6.555).

  7. Guo C, Wang P, Lin X, Salendra L, Yang B, Zhou X, Liao S, Wang J*,Liu Y.* Phloroglucinol heterodimers and bis-indolyl alkaloids from the sponge-derived fungusAspergillus sp. SCSIO 41018.Organic Chemistry Frontiers,2019, 6,3053-3059 (IF 5.076, 封面文章).

  8. Luo X, Chen C,Tao H, Lin X, Yang B, Zhou X,Liu Y.*Structurallydiversediketopiperazinealkaloids from themarine-derivedfungusAspergillus versicolorSCSIO 41016.Organic Chemistry Frontiers,2019, 6, 736-740 (IF5.076).

  9. Li K, Liang Z, Chen W, Luo X, Fang W, Liao S, Lin X, Yang B, Wang J, Tang L,* Liu Y, * Zhou X* Iakyricidins A‒D, antiproliferative piericidin analogs bearingcarbonyl group or cyclic skeleton fromStreptomyces iakyrus SCSIO NS104.Journal of Organic Chemistry, 2019, 84(19),12626-12631 (IF 4.745, 封面文章).  

  10. Liao S, Qin X, Wang Z, Li D, Xu L, Li J, Tu Z,Liu Y*. Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivatives.European Journal of Medicinal Chemistry, 2016, 121, 500-509(IF4.833).

  11. Liao S, Qin X, Li D, Tu Z, Li J, Zhou X, Wang J, Yang B, Lin X, Liu J, Yang X,Liu Y*. Design and synthesis of novel soluble 2,5-diketopiperazine derivatives as potential anticancer agents.European Journal of Medicinal Chemistry, 2014, 83, 236-244(IF4.833).

  12. Li T,Hu S,Pang X,Wang J,Yin J,Li F,Wang J,Yang X,Xia B,Liu Y,Song W,Guo S.The marine-derived furanone reduces intracellular lipidaccumulation in vitro by targeting LXRα and PPARα.JournalofCellular andMolecularMedicine 2020,24,3384-3398 (IF 4.658).

  13. Wang J,He W,Kong F,Tian XWang P,Zhou X,Liu Y*. Ochracenes A-I, humulane-derived sesquiterpenoids from theAntarctic fungusAspergillus ochraceopetaliformis.Journal of Natural Products,2017, 6, 1725-1733 (IF4.257).

  14. Wang J, Wei X, Qin X, Tian X, Liao L, Zhou X, Yang X, Wang F, Tu Z, Chen B,Liu Y*.Antiviral merosesquiterpenoids produced by an antarctic fungusAspergillus ochraceopetaliformisSCSIO 05702.Journal of Natural Products, 2016, 79(1), 59-65 (IF 4.257).

  15. Yang X, Peng K, Liu Z, Zhang G, Li J, Wang N*, Steinmetz A,Liu Y*. Strepsesquitriol, a rearranged zizaane-type sesquiterpenoid from the deep-sea-derived actinomyceteStreptomyces sp. SCSIO 10355. Journal of Natural Products,2013, 76, 2360-2363 (IF 4.257).

  16. Li P, Liu X, Zhu H, Tang X, Shi X,Liu Y*, Li G*.Unusual inner-salt guaiazulene alkaloids and bis-sesquiterpene from the South China Sea gorgonianMuriceides collaris.Scientific Reports, 2017,7, 7697 (IF4.011).

  17. Zheng J, Wang J, Wang Q, Zou H, Wang H,Zhang H, Chen J, Wang Q, Wang P,  Zhao Y, Lu J, Zhang X, Xiang S, Wang H, Lei J, Chen H, Liu P,Liu Y,* Han F,*  Wang J.*Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin.Acta Pharmaceutica Sinica B, 2020,doi.org/10.1016/j.apsb.2020.07.001.

  18. Chen W, Chen C,Long J,Lan S,Lin, X, Liao S,Yang B,Zhou X,Wang, J,Liu Y.Bioactive secondary metabolites from the deep-sea derived fungus Aspergillus sp. SCSIO 41029.JOURNAL OF ANTIBIOTICS, 2020,DOI: 10.1038/s41429-020-00378-y.

  19. Liang Y, Huang H, Li Y, Du R, Li J, Liu Y, Li S, Zhang L. Efficient synthesis of cholic acid derivates through stereoselective C-H functionalization from hyodeoxycholic acidSteroids, 2020, 157, 108594.

  20. Lin X, Ai W , Li M, Zhou X, Liao S, Wang J, Liu J, Yang B,Liu Y.* Collacyclumines A–D from the endophytic fungusColletotrichum salsolaeSCSIO 41021 isolated from the mangroveKandelia candel.Phytochemistry 2020, 171, 12237 (IF 2.905).

  21. Han W, Cai J, Zhong W, Xu G, Wang F, Tian X, Zhou X, Liu Q,Liu Y, Wang J. Protein tyrosine phosphatase 1B (PTP1B) inhibitors from the deep-sea fungus Penicillium chrysogenum SCSIO 07007.Bioorganic Chemistry 2020, 96, 103646 (IF 3.926).

  22. Chen X, Xing N, Yang B, Zhou X, Gao C,Liu Y.* Two novel sesquiterpenes and a new pregnane derivative from the South China Sea gorgonianSubergorgia suberosa.Records Natural Products 2020, 14, 57-64. 

  23. Yang Z, Kaliaperumala K, Zhang J, Liang Y, Guo C, Zhang J, Yang B,Liu Y. Antifungal fatty acid derivatives againstPenicilliumitalicum from the deep-sea fungusAspergillus terreus SCSIO 41202.Natural Products Research 2020, https://doi.org/10.1080/14786419.2020.1716350.

  24. Lin X, Ai W, Li M, Pang X, Ju Z, Guan D, Yang B, Zhou X, Wang J, Liu J, Wang L, Liu Y. Colletoindole A from the mangrove plant endophytic fungus Colletotrichum tropicale SCSIO 41022.Chemistry & Biodiversity 2020, 17, e1900040.

  25. Li K, Cai J, Su Z, Yang B, Liu Y, Zhou X, Huang J, Tao H. Glycosylated natural products from marine microbes.Frontiers Chemistry, 2020,https://doi.org/10.3389/fchem.2019.00879

  26. Chen W, Liu H, Long J, Tao H, Lin X, Liao S, Yang B, Zhou X, Liu Y, Wang J. Asperpentenone A, A novel polyketide isolated from the deep-sea derived fungus Aspergillus sp. SCSIO 41024.Phytochemistry Letters 2020, 35, 99–102

  27. Luo X, Gao C, Lu H, Wang J, Su Z, Tao H, Zhou X, Yang B, Liu Y. HPLC-DAD-guided isolation of diversified chaetoglobosins from the coral-associated fungus Chaetomium globosum C2F17. Molecules 2020, 25, 1237; doi:10.3390/molecules25051237

  28. Peng Y, Cao L, Liu Y, Huang R. Sargassulfamide A, an unprecedented amide derivative from the seaweed Sargassum naozhouense.Chemistry of Natural Compounds, 2020, 56, DOI 10.1007/s10600-020-02952-0. 

  29. Pang X, Lin X, Zhou X, Yang B, Tian X, Wang J,* Shihai Xu,* Liu Y.*New quinoline alkaloid and bisabolane-type sesquiterpenoid derivatives from the deep-sea-derived fungus Aspergillus sp. SCSIO06786.Fitoterapia, 2020, 140, 104406.

  30. Tan Y, Deng W, Zhang Y, Ke M, Zou B, Luo X, Su J, Wang Y, Xu J, Nandakumar KS, Liu Y, Zhou X, Li X. A marine fungus-derived nitrobenzoyl sesquiterpenoid suppresses receptor activator of NF-κB ligand-induced osteoclastogenesis and inflammatory bone destruction.British Journalof Pharmacology2020, 177, 4242-4260.

  31. Luo X,Lu H,Chen X,Zhou X,Gao C,Liu Y.Secondary Metabolites And Their Biological Activities From The Sponge Derived Fungus Aspergillus Versicolor.Chemistryof Natural Compounds, 2020, 56(4), 716-719.

  32. Guo C,Lin X,Liao S,Yang B,Zhou X,Yang X,Tian X,Wang J,Liu Y.*Two new aromatic polyketides from a deep-sea fungusPenicillium sp. SCSIO 06720. NaturalProductResearch, 2020, 34, 9, 1197-1205.

  33. Wang J,Liang Z,Li KLYang B,Liu Y,Fang W,Tang L,Zhou X. Ene-yne Hydroquinones from a Marine-derived Strain of the Fungus Pestalotiopsis neglecta with Effects on Liver X Receptor Alpha.Journalof Natural Products, 2020, 83, 4, 1258-1264.

  34. Wang J,Peng Q,Yao X,Liu Y,Zhou X. New pestallic acids and diphenylketone derivatives from the marine alga-derived endophytic fungus Pestalotiopsis neglecta SCSIO41403.Journalof Antibiotics, 2020, 73, 8, 585-588.

  35. Chen W,Li K,Lin X,Liao S,Yang B,Zhou, X,Wang J,Liu Y,Wang J. Antioxidant CPA-type indole alkaloids produced from the deep-sea derived fungusAspergillus sp. SCSIO 41024.Natural Product Research, 2020, DOI: 10.1080/14786419.2020.1749614

  36. Long J,Wang J,Liao S,Lin X,Zhou X,Li YYang BLiu Y.Four new steroids from the marine soft coral-derived fungus Penicillium sp. SCSIO41201. Chinese Journalof Natural Medicines, 2020, 18(4), 250-255.

  37. Chen C,Tao H,Chen W,Yang B,Zhou X,Luo X,Liu Y. Recent advances in the chemistry and biology of azaphilones.RSC Advances, 2020, 10(17), 10197-10220.

  38. Luo X,Lin Y,Lu Y,Zhou X,Liu Y.* Peptides and polyketides isolated from the marine sponge-derived fungusAspergillus terreus SCSIO 41008.Chinese Journal of Natural Medicines, 2019, 17(2), 149-154.

  39. Liu N, Peng S, Yang J, Cong Z, Lin X, Liao S, Yang B, Zhou X, Zhou X, Liu Y,* Wang J.* Structurally diverse sesquiterpenoids and polyketides from a sponge-associated fungusAspergillus sydowii SCSIO41301.Fitoterapia,2019,135, 27-32.

  40. Xu H, Xu L, Luo X, Wang J, Zhou X, Yang B, Li D, Luo Z,Liu Y,* Liao S.* Transition-metal-free insertion of benzyl bromides into 2-(1H- benzo[d]imidazol-1-yl) benzaldehyde: One-pot switchable syntheses of benzo[4,5]imidazo[1,2-a]quinolin-5(7H)-ones and 3-arylquinolin-4-ones mediated by base.Tetrahedron, 2019, 75(19), 2785-2796.

  41. Zhou X,* Liang Z, Li K, Fang W, Tian Y, Luo X, Chen Y, Zhan Z, Zhang T, Liao S, Liu S,Liu Y, Fenical W, Tang L.*Exploring the natural piericidins as anti-renal cell carcinoma agents targeting peroxiredoxin 1.Journal of Medicinal Chemistry, 2019, 62(15), 7058-7069 (IF 4.745).

  42. Salendra L, Luo X, Lin X, Wang J, Yang Y, Zhou X,Liu Y. Versispiroketal A, an unusual tetracyclic bridged spiroketal from the sponge-associated fungusAspergillus versicolor SCSIO 41013.Organic & Biomolecular Chemistry, 2019, 17, 2182-2186 (IF 3.490).

  43. Wang J, Qin L, Zhao B, Cai L, Zhong Z,Liu Y, Zhou X. Crotonols A and B, two rare tigliane diterpenoid derivatives against K562 cells fromCroton tiglium.Organic & Biomolecular Chemistry,2019, 17, 195-202 (IF 3.490).

  44. Wang J, Li K, Luo X, Wu Z, Gu T, Liao S, Lin X, Yang B,Liu Y, Fang W,* Zhou X.*  Sorbicillfurans A and B, two novel sorbicillinoid adducts from the fungus Penicillium citrinum SCSIO41402.Organic & Biomolecular Chemistry,2019, 17, 8721-8725 (IF 3.490).

  45. Fredimoses M, Zhou X, Ai W, Tian X, Bin B, Lin X, Liu J,Liu Y.* Emerixanthone E, a new xanthone derivative from deep sea fungusEmericella sp SCSIO 05240.NaturalProductResearch, 2019, 33(14), 2088-2094.

  46. Tan S, Yang B, Liu J, Xun T,Liu Y, Zhou X.Penicillixanthone A, a marine-derived dual-coreceptor antagonist as anti-HIV-1 agent.NaturalProductResearch, 2019, 33(10), 1467-1471.  

  47. Lei L, Lei J, Zhou X, Hu M, Niu H, Song C, Chen S,LiuY,* Zhang D.* Cytotoxic Polyketides from the Marine Sponge-Derived FungusPestalotiopsisheterocornisXWS03F09.Molecules,2019, 24, 2655; doi:10.3390/molecules24142655.

  48. Pang X, Cai G, Lin X, Salendra L, Zhou X, Yang B, Wang J, Wang J,* Xu S,*LiuY.* New Alkaloids and Polyketides from the Marine Sponge-Derived Fungus Penicillium sp. SCSIO41015.Marine Drugs, 2019, 17, 398; doi:10.3390/md17070398.

  49. Luo X, Chen C,Li KLin X,Gao C,Zhou X,Liu Y.* Sesquiterpenoids and meroterpenoids from a mangrove derived fungusDiaporthe sp. SCSIO 41011.NaturalProductResearch, 2019, DOI: 10.1080/14786419.2019.1627355.

  50. Salendra LLin X,Chen W,Pang, X,Luo X,Long J,Liao S,Wang J,Zhou X,Liu Y.* Cytotoxicity of polyketides and steroids isolated from the sponge-associated fungus Penicillium citrinum SCSIO 41017.NaturalProductResearch, 2019, DOI: 10.1080/14786419.2019.1610757.

  51. Li Y,Tan Y,Liu JZhou X,Zeng S,LiuY,Yang B. A new griseofulvin derivative from a soft coral-derived fungus Eupenicillium sp. SCSIO41208.NaturalProductResearch, 2019, DOI: 10.1080/14786419.2019.1596093.

  52. Lin X, Li K,Yang L,Peng X,Fang W,Tian X,Liu Y,Zhou X*. Dereplication and targeted isolation of bioactive sulphur compound from bacteria isolated from a hydrothermal field.Natural Product Research, 2019, 33(4), 494-499.

  53. Luo X,Gao C,Han F,Chen X,Lin X,Zhou X,Wang J,Liu Y.* A new naphthopyranone from the sponge-associated fungusPenicillium sp. XWS02F62.  Magnetic Resonancein Chemistry, 2019, 57(11), 982-986.

  54. Peng Y,Li JF,Huang RM,Liu Y.Chemical Constituents of the South China Sea Starfish Stellaster equestris.Chemistry Of Natural Compounds, 2019, 55(6), 1190-1191.

  55. Pang X, Lin X, Yang J, Zhou X, Yang B, Wang J,* Liu Y.* Spiro-phthalides and isocoumarins isolated from the marine-sponge-derived fungusSetosphaeria sp. SCSIO41009.Journal of Natural Products,2018, 81(8),1860-1866 (Most read articles, IF 3.947).

  56. Luo X, Lin X, Tao H, Wang J, Li J, Yang B, Zhou X,*Liu Y.* Isochromophilones A-F, cytotoxic chloroazaphilones from the marine mangrove endophytic fungusDiaporthe sp SCSIO 41011.Journal of Natural Products, 2018, 81 (4), 934-941. 

  57. Dai Y, Lin Y, Pang X, Luo X, Salendra L, Wang J, Zhou X, Lu Y, Yang B,*Liu Y.* Peptides from the soft coral-associated fungusSimplicilliumsp. SCSIO41209.Phytochemistry,2018, 154, 56-62.

  58. Yang B,Huang J,Zhou X,Lin X,Liu J,Liao S,Wang J,Liu F,Tao H,Liu Y.* The fungal metabolites with potential antiplasmodial activity. CurrentMedicinalChemistry, 2018, 25(31), 3796-3825.

  59. Pang X, Lin X, Wang P, Zhou X, Yang B, Wang J,* LiuY.Perylenequione derivatives with anticancer activities isolated from the marine sponge-derived fungus,Alternaria sp. SCSIO41014Marine Drugs,2018, 16(8), 280.

  60. Luo X, Yang J, Chen F, Lin X, Chen C, Zhou X,* Liu S,*Liu Y.* Structurally diverse polyketidesfrom the mangrove-derived fungusDiaporthe sp. SCSIO 41011 with their anti-influenza A virus activities.Frontiers in Chemistry,2018, 6, 282.

  61. Tian Y, Lin X, Zhou X,* Liu Y.* Phenol derivatives from the sponge-derived fungusDidymellaceae sp. SCSIO F46.Frontiers in Chemistry, 2018, 6, 536.

  62. Yang B, Tao H, Lin X, Wang J, Liao S, Dong J, Zhou X,*LiuY.* Prenylated indole alkaloids and chromone derivatives from the fungus Penicillium sp. SCSIO041218.Tetrahedron, 2018, 74, 77-82.

  63. Peng Y, Huang R, Lin X,Liu Y*. Norisoprenoids from the brown algaSargassum naozhouense Tseng et Lu. Molecules, 2018, 23, 348.

  64. Gu Y, Ding P, Liang Z, Song Y,Liu Y, Li J.*Activated production of silent metabolites from marine-derived fungusPenicillium citrinum.Fitoterapia, 2018, 127, 207-211.

  65. Zhang J*, Yang Z, Liang Y, Zhong L, Lin H, Zhong B, Li L,* Xu S,*Liu Y. Four New C9 metabolites from the sponge-associated fungusGliomastixsp. ZSDS1-F7-2.Marine Drugs 2018, 16, 231.

  66. Limbadri S, Luo X, Lin X, Liao S, Wang J, Zhou X, Yang B,* LiuY.* Bioactive novel indole alkaloids and steroids from deep sea-derived fungus Aspergillus fumigatus SCSIO 41012.Molecules, 2018, 23(9), 2379.

  67. Chen Y, Chen R, Xu J, Tian Y,*, Xu J,*LiuY.* Two New altenusin/thiazole hybrids and a new benzothiazole derivative from the marine sponge-derived fungusAlternaria sp. SCSIOS02F49.Molecules, 2018, 23, 2844.

  68. Xie C, Xia J, Su R, Li J,Liu Y, Yang X,* Yang Q.* Bacilsubteramide A, a new indole alkaloid, from the deep-sea-derivedBacillus subterraneus 11593.NaturalProductResearch, 2018, 32(21), 2553-2557.

  69. Fang W, Wang J, Wang J, Shi L, Li K, Lin X, Min Y, Yang B, Tang L,Liu Y, Zhou X. Cytotoxic and antibacterial eremophilane sesquiterpenes from the marine-derived fungusCochliobolus lunatus SCSI041401.Journal of Natural Products,2018, 81(6), 1405-1410.

  70. Tian Y,Lin S,Zhou H,Lin S,Wang S,Liu Y*.Protuboxepin C and protuboxepin D from the sponge-derived fungusAspergillus sp SCSIO XWS02F40.NaturalProductResearch, 2018, 32(21), 2510-2515.

  71. Tian Y,Lin SKumaravel KZhou HWang SLiu Y*. Polyketide-derived metabolites from the sponge-derived fungusAspergillussp F40.Phytochemistry Letters, 2018, 27, 74-77.

  72. Luo X, Zhou X,*Liu Y.* Nitrogenous compounds produced by the deep sea derived fungus Leptosphaeria sp. SCSIO 41005.Natural Product Communications, 2018, 13(6), 677-678.

  73. Tan Y, Yang B, Lin X, Luo X, Pang X, Tang L,Liu Y, Li X*, Zhou X*. Nitrobenzoyl sesquiterpenoids with cytotoxic activities from a marine-derivedAspergillus ochraceus fungus.Journal of Natural Products, 2018, 81(1), 92-97.

  74. Pang X,Lin X,Tian Y,Liang RWang J,Yang B,Zhou X,Kaliyaperumal K,Luo X,Tu Z,Liu Y*. Three new polyketides from the marine sponge-derived fungusTrichoderma sp. SCSIO41004.NaturalProductResearch, 2018, 32(1), 105-111.

  75. Pang X,Lin X, Wang J,Liang R, Tian Y, Salendra L,Luo X,Zhou X,Yang B,Tu Z,Liu Y*. Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungusCladosporiumsp . SCSIO41007.Steroids, 2018, 41-46.

  76. Wang J, Zhou L, Chen S, Yang B, Liao S, Kong F, Lin X, Wang F, Zhou X,Liu Y*. New chlorinated diphenyl ethers and xanthones from a deep-sea-derived fungusPenicillium chrysogenum SCSIO 41001. Fitoterapia, 2018, 125, 49-54.

  77. Lei H, Lin X, Han L, Ma J, Dong K, Wang X, Zhong J, Mu Y,Liu Y, Huang X*. Polyketide derivatives from a marine-sponge-associated fungusPestalotiopsis heterocornis.Phytochemistry, 2017, 142, 51-59.

  78. Ju Z, Lin X, Li M, Wang y, Tian Y, Wang J, Liu J, Tu Z, Xu S*,Liu Y*.Chaetochromones A-C, three new polyketides from mangrove plant derived endophytic fungusPhomopsis sp. SCSIO 41006.Chemistry & Biodiversity, 2017, 14(11), e1700266 and e1870034.

  79. Lin X, Wu Q, Yu Y, Liang Z,Liu Y, Zhou L*, Tang L*, Zhou X*. Penicilliumin B, a novel sesquiterpene methylcyclopentenedione from a deep sea-derivedPenicilliumstrain with renoprotective activities.Scientific Reports, 2017, 7(1), 10757.

  80. Li Y,Wang J,He W,Lin X,Zhou X,Liu Y*. One strain-many compounds method for production of polyketide metabolites using the sponge-derived fungusArthrinium arundinis ZSDS1-F3. Chemistry of Natural Compounds, 2017, 53(2), 373-374.

  81. Lei HLin X,Han LMa JMa Q,Zhong J,Liu Y,Sun T,Wang J,Huang X. New metabolites and bioactive chlorinated benzophenone derivatives produced by a marine-derived fungusPestalotiopsis heterocornis.MarineDrugs, 2017, 15(3), 69.

  82. Luo X, Lin X,Salendra L,Pang X,Dai Yu,Yang BinLiu JuanWang J,Zhou X*,Liu Y*. Isobenzofuranones and isochromenones from the deep-sea derived fungusLeptosphaeria sp. SCSIO 41005.MarineDrugs, 2017, 15(7), 204.

  83. Wang J,Liang R,Liao S,Yang B,Tu Z,Lin X,Wang B,Liu Y*. Vaccinols J-S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungusPestalotiopsis vaccinii.Fitoterapia, 2017, 120,164-170.

  84. Wang L, Wang J, Liu J,Liu Y*. Antitubercular marine natural products.Current Medicinal Chemistry, 2018, 25, 2304-2328. 

  85. Luo X, Zhou X,Lin X, Qin X,Zhang T,Wang J,Tu Z,Yang B,Liao S,Tian Y,Pang X, Kaliyaperumal K,Li JL,Tao H,Liu Y*. Antituberculosis compounds from a deep-sea-derived fungusAspergillussp. SCSIO Ind09F01. Natural Product Research, 2017, 31(16), 1958-1962.

  86. Liao SRTang YXu LZhou XFWang JF,Yang BLiu Y*. Ring-contraction from benzo[b][1,4]thiazines to benzo[d]thiazolines induced by oxygen.Tetrahedron, 2017, 73(1), 98-107.

  87. Xian J, Lin X, Lu X, Wan J, Wang J, Zhou X,AiW, Tu Z,Liu Y*. Pestalachloride E, a new chlorinated benzophenone derivative from mangrove endophytic fungusPestalotiopsis versicolor.ChineseJournal of Antibiotics,2017,42, 8-13.

  88. Yang B, Tao H, Qin X, Wang Z, Dong J, Lin X, Zhou X, Li J, Tu Z,Liu Y*. Aspergone, a new chromanone derivative from fungusAspergillus sp. SCSIO41002 derived of mangrove soil sample.Journal of Antibiotics,2017,6, 788-790.

  89. Chen S, Wang J, Wang Z, Lin X, Zhao B, Kaliaperumal K, Liao X, Tu Z, Li J, Xu S,Liu Y*. Structurally diverse secondary metabolites from a deep-sea-derived fungusPenicillium chrysogenumSCSIO 41001 and their biological evaluation.  Fitoterapia, 2017, 17, 71-78.

  90. He WJ, Zhou XJ, Qin XC, Mai YX, Lin X, Liao S, Yang B, Zhang T, Tu Z,Liu Y*. Quinone/hydroquinone meroterpenoids with antitubercular and cytotoxic activities produced by the sponge-derived fungusGliomastixsp. ZSDS1-F7.Natural Product Research, 2017, 31(5), 604-609.

  91. Wang J, Qin X, Chen Z, Ju Z, He W, Tan Y, Zhou X, Tu Z, Lu F*,Liu Y*. Two new anthraquinones with antiviral activities from the barks ofMorinda citrifolia (Noni). Phytochemistry Letters, 2016, 15, 13-15.

  92. Zhao BQPeng SHe WJLiu YWang JF,Zhou X*. Antitubercular and cytotoxic tigliane-type diterpenoids fromCroton tiglium.Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 4996–4999.

  93. Kim A, Kim M, Noh T, Hong J,Liu Y, Wei X, Jung J*. Synthesis and antibacterial evaluation of hamacanthin B analogues.Bioorganic & Medicinal Chemistry Letters, 2016, 26(20), 5013–5017.

  94. Kim E, Li J, Hong J, Yoon W, Kim H,Liu Y, Wei X, Jung J*. An unusual 1(10-19)abeo steroid from a jellyfish-derived fungus.Tetrahedron Letters, 2016, 57(25), 2803-2806.

  95. Wang H, Hong J, Yin J, Liu J,Liu Y, Choi J, Jung, J*. Paecilonic acids A and B, bicyclic fatty acids from the jellyfish-derived fungusPaecilomyces variotiiJ08NF-1.Bioorganic & Medicinal Chemistry Letters, 2016, 26(9), 2220-2223.

  96. Xu G, Wang Z, Zhao B, Liu N, Yang S,Liu Y, Wang J*, Zhou X.* Saniculamins A and B, two new flavonoids fromSanicula lamelligeraHance inhibiting LPS-induced nitric oxide release. Phytochemistry Letters,2016, 18, 35-38.

  97. Liu J, Jung J,Liu Y*. Antimicrobial compounds from marine invertebrates-derived microorganisms.Current Medicinal Chemistry, 2016,23(25), 2892-2905.

  98. Wang J, He W, Huang X, Tian X, Liao S, Yang B, Wang F, Zhou X,Liu Y*.Antifungal new oxepine-containing alkaloids and xanthones from the deep-sea-derived fungusAspergillus versicolor SCSIO 05879.Journal of Agriculture and Food Chemistry,2016, 64, 2910-2916.

  99. Zhou X, Fang W, Tan S, Lin X, Xun T, Yang B, Liu S,Liu Y*. Aspernigrins with anti-HIV-1 activities from the marine-derived fungusAspergillus nigerSCSIO Jcsw6F30.Bioorganic & Medicinal Chemistry Letters, 2016, 26, 361-365.

  100. Tian Y, Lin X, Wang Z, Zhou X, Qin X, Kaliyaperumal K, Zhang T, Tu Z,Liu Y*. Asteltoxins with antiviral activities from the marine sponge-derived fungusAspergillus sp. SCSIO XWS02F40.Molecules, 2016, 21(1), 34.

  101. Liao S , Du L, Qin X, Xu L, Wang J, Zhou X, Tu Z, Li J*,Liu Y*. Site selective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6Z)-2,5-diketopiperazines via a one-pot multicomponent method.Tetrahedron, 2016, 72(8), 1051-1057.

  102. Fang W, Lin X, Wang J,Liu Y, Tao H, Zhou X*. Asperpyrone-Type bis-naphtho--pyrones with cox-2-inhibitory activities from marine-derived fungusAspergillus niger.Molecules, 2016, 21(7), 941.

  103. Ju ZR,Qin XC,Lin XP,Wang JF,Kaliyaperumal K,Tian YQ,Liu J,Liu F,Tu ZC,Xu SH,Liu Y*.New phenyl derivatives from endophytic fungusBotryosphaeriasp. SCSIO KcF6 derived of mangrove plantKandelia candel.Natural Product Research, 2016, 30(2), 192-198.

  104. Yang B, Huang J, Lin X, Zhang Y, Tao H,Liu Y*. A new diketopiperazine from the marine spongeCallyspongia species.Records of Natural Products, 2016, 10 (1), 117-121.

  105. Yang B, Huang J, Li X, Lin X, Zhou X, Tao H,Liu Y*. Isolation, Characterization, and Bioactivity Evaluation of Alkaloids from Soft CoralSinularia kotanianensis.Chemistry of Natural Compounds, 2016, 52(3), 564-566.

  106. Tao G, Liu J, Jung JH, Guo W, Wen XQ,LiuY*. Compounds from a jellyfish-derived fungusAspergillus fumigates.Natural Product Sciences, 2016, 22(2):82-86.

  107. Wang H, Hong J, Yin J, Moon H, Liu YWei X, Oh D, Jung J*. Dimeric Octaketide Spiroketals from the Jellyfish-Derived FungusPaecilomyces variotiiJ08NF-1.Journal of Natural Products, 2015, 78(11), 2832-2836.

  108. Liao S, Xu Y, Tang Y, Wang J, Zhou X, Xu L,Liu Y*. Design, synthesis and biological evaluation of soluble 2,5-diketopiperazines derivatives as potential antifouling agents.RSC Advances, 2015, 5, 5, 51020-51026

  109. Wang J, He W, Qin X, Wei X, Tian X, Liao L, Liao S, Yang B, Tu Z, Chen B, Wang F, Zhou X,Liu Y*. Three new indolyl diketopiperazine metabolites from the antarctic soil-derived fungusPenicilliumsp SCSIO 05705.RSC Advances, 2015, 5(84), 68736-68742.

  110. Zhang J, Lin X, Li L, Zhong B, Liao X,Liu Y*, Xu S*. Gliomasolides A–E, unusual macrolides from a sponge-derived fungusGliomastix sp. ZSDS1-F7-2. RSC Advances,2015, 5, 54645–54648.

  111. Bai Z, Lin X, Wang J, Zhou X, Liu J, Yang Y, Yang X, Liao S, Wang L,Liu Y*.New meroterpenoids from the endophytic fungusAspergillus flavipesAIL8 derived from the mangrove plantAcanthus ilicifolius.Marine Drugs, 2015, 13, 237-248.

  112. Liu J, Wei X, Kim E, Lin X, Yang X, Zhou X, Yang B, Jung J,Liu Y*. New glucosidated pyrazinoquinazoline indole alkaloids from fungusAspergillus fumigatusderived of a jellyfish.Tetrahedron, 2015, 71, 271-275.

  113. Wang J, Wang Z, Ju Z, Wan J, Liao S,  Lin X, Zhang T, Zhou X,Chen H, Yang B, Tu Z, Liu Y*.Cytotoxic cytochalasins from marine-derived fungusArthrinium arundinisZSDS1-F3.Planta Medica, 2015, 81, 160-166.

  114. Li J, Huang L, Liu J, Song Y, Gao J, Jung J, Liu Y*, Chen G*. Acetylcholinesterase inhibitory dimeric indole derivatives from the marine actinomycetesRubrobacter radiotoleransFitoterapia, 2015, 102, 203-207.

  115. Wang J, Yang S, Liu Y, Li D, He W, Zhang X,Liu Y*, Zhou X*. Five new phorbol esters with cytotoxic and selective anti-inflammatory activites fromCroton tiglium.Bioorganic & Medicinal Chemistry Letters, 2015, 25(9), 1986-1989.

  116. Wang L, Wang J, Wang L, Ma S,Liu Y*.Anti-enterovirus 71 agents of natural products.Molecules, 2015,20(9), 16320-16333.

  117. Qin C, Lin X, Lu X, Wan J, Zhou X, Liao S, Tu Z, Xu S,Liu Y*. Sesquiterpenoids and xanthones derivatives produced by sponge-derived fungusStachybotry sp. HH1 ZSDS1F1-2.Journal of Antibiotics,2015,68, 121-125.

  118. Ai W,Lin L,Wang Z,Lu X,Mangaladoss F,Yang X, Zhou X,Tu Z,Liu Y*.Cladosporone A, a new dimeric tetralone from fungusCladosporiumsp. KcFL6’ derived of mangrove plantKandelia candel.Journal of Antibiotics,2015, 68, 213-215.

  119. Tian Y, Qin X, Lin X, Kumaravel K, Zhou X, Liu J, Ju Z, Tu Z, Liu Y*. Sydoxanthone C and acremolin B produced by deep-sea-derived fungusAspergillussp. SCSIO Ind09F01.Journal of Antibiotics,2015, 68, 703-706.

  120. Ju Z,Lin X,Lu X,Tu Z,Wang J,Kaliyaperumal K,Liu J,Tian Y,Xu S,* Liu Y*. Botryoisocoumarin A, a new COX-2 inhibitor from the mangrove Kandelia candel endophytic fungusBotryosphaeria sp KcF6. Journal of Antibiotics,2015, 68, 653-656.

  121. Ai W, Lin X, Tu Z, Tian X, Lu X, Mangaladoss M, Zhong J,Liu Y*. Axinelline A, a new COX-2 inhibitor from Streptomyces axinellae SCSIO02208.Natural Product Research,2015, 68, 213-215.

  122. Tian Y,Lin X, Liu J, Kaliyaperumal K, Ai W, Ju J, Yang Y, Wang J, Yang X,Liu Y*.Ascomycotin A, a new citromycetin analogue produced byAscomycotasp. Ind19F07 isolated from deep sea sediment.Natural Product Research,2015, 29(9), 820-826.

  123. Sun J, Yang B, Zhou X, Yang X, Wang L, Liu Y*. A new briarane-type diterpenoid from the South China Sea GorgonianDichotella gemmacea.Natural Product Research,2015, 29(9), 807-812.

  124. Fredimoses M, Zhou X, Ai W, Tian X, Yang B, Lin X, Xian J,Liu Y*.Westerdijkin A, a new hydroxyphenylacetic acid derivative from deep sea fungusAspergillus westerdijkiae SCSIO 05233.Natural Product Research,2015, 29(2), 158-162.

  125. Wang J, Qin X, Xu F, Zhang T, Liao S, Lin X, Yang B, Liu J, Wang L, Tu Z,Liu Y*. Tetramic acid derivatives and polyphenols from sponge-derived fungus and their biological evaluation.Natural Product Research,2015, 29(18), 1761-1765.

  126. Yang B, Huang J, Lin X, Liao S, Zhou X, Liu J, Wang J, Wang L,Liu Y*. New casbane diterpenoids from the Hainan soft coralSinularia species.Helvetica Chimica Acta, 2015, 98(6), 834-841.

  127. Wang J, Wei X, Qin X, Chen H, Lin X, Zhang T, Yang X, Liao S, Yang B, Liu J, Zhou X, Tu Z,Liu Y*. Two new prenylated phenols from endogenous fungusPestalotiopsis vacciniiof mangrove plantKandelia candel (L.) Druce.Phytochemistry Letters, 2015, 12, 59-62.

  128. Huang R, Chen Y, Zhou X, Yang X,Liu Y*. A new N-Acyl taurine from the South China Sea marine spongeCallyspongiasp.Chemistry of Natural Compounds, 2015, 51(3), 540-541.

  129. Sun J, Wu Y, Yang B,Liu Y*. Chemical constituents of marine spongeHalichondriasp. from South China Sea. Chemistry of Natural Compounds, 2015, 51(5), 975-977.

  130. Wang H, Hong J, Yin J, Moon H,Liu Y, Wei X, Oh D, Jung JH*.Dimeric Octaketide spiroketals from the jellyfish-derived fungusPaecilomyces variotiiJ08NF-1,Journal of Natural Products, 2015, 78(11), 2832-2836.

  131. Yang X, Miao Z, Ma X, Zhang G, Steinmetz A, Yang B, Wang J, Liu J,Liu Y, Wang N. Asterolloside, a novel enolic saccharide from the sea starAsterias rollestoni Bell.Tetrahedron Letters, 2015, 56, 6174-6176.

  132. Wang J, He W, Zhang X, Zhao B,Liu Y,Zhou X*. Dicarabrol, a new dimeric sesquiterpene from Carpesium abrotanoides L.Bioorganic & Medicinal Chemistry Letters, 2015, 25, 4082-4084.

  133. Wang B, Wang L, Li Y,Liu Y*. Heterocyclic terpenes: linear furano-and pyrroloterpenoids.RSC Advances, 2014,4, 12216-12234.

  134. Lei H, Sun S, Han Z, Zhou X, Yang B,Liu Y*. Fragilisinins A-L, new briarane-type diterpenoids from gorgonianJunceella fragilis.RSC Advances,2014,4(10), 5261-5271.

  135. Wang L, Zhou X, Fredimoses M, Liao S,Liu Y*.Naturally occurring organoiodines. RSC Advances, 2014, 4 (101), 57350- 57376.

  136. Fredimoses M, Zhou X, Lin X, Tian X, Ai W, Wang W, Liao S, Liu J, Yang B, Yang X,Liu Y*.New prenylxanthones from the deep-sea derived fungusEmericella sp. SCSIO 05240.Marine Drugs, 2014, 12(6), 3190-3202.

  137. Yang B,Wei X,Huang J,Lin X,Liu J,Liao S,Wang J,Zhou X,Wang L,Liu Y*.Sinulolides A-H, new cyclopentenone and butenolide derivatives from softcoralSinulariasp.Marine Drugs, 2014, 12(10), 5316-5327.

  138. Yang B, Dong J, Lin X, Zhou X, Zhang Y,Liu Y*.New prenylated indole alkaloids from fungusPenicilliumsp. derived of mangrove soil sample.Tetrahedron, 2014, 70(25), 3859–3863.
  139. Ai W,Wei X,Lin X,Sheng L,Wang Z,Tu Z,Yang X,Zhou X,Li J,Liu Y*.Guignardins A-F, spirodioxynaphthalenes from the endophytic fungusGuignardiasp KcF8 as a new class of PTP1B and SIRT1 inhibitors.Tetrahedron, 2014, 70(35), 5806-5814.

  140. Wang J, Wei X, Lu X,Xu F, Wan J, Lin X, Zhou X,Liao S,Yang B, Tu Z,Liu Y*. Eight new polyketide metabolites fromthe fungusPestalotiopsis vacciniiendogenous with the mangrove plantKandelia candel(L.) Druce.Tetrahedron, 2014,70, 9695-9701.

  141. Fang W, Lin X, Zhou X, Ai W, Lin J. Yang B, Tu C,Liu Y*. Cytotoxic and antiviral sesquiterpenoid nitrobenzoyl esters from the marine-derived fungusAspergillussp. Jcma1F17. MedChemComm,2014, 5, 701-705.

  142. Bai Z, Lin X, Wang Y, Wang J, Zhou X, Yang B, Liu J, Yang X, Wang Y,Liu Y*. New phenyl derivatives from endophytic fungusAspergillus flavipes AIL8 derived of mangrove plantAcanthus ilicifolius. Fitoterapia, 2014, 95, 194-202.

  143. Sun J, Lin X, Zhou X, Wan J, Zhang T, Yang B, Yang X, Tu Z,Liu Y*.PestalolsA-E, newalkenyl phenol and benzaldehydederivatives from endophytic fungusPestalotiopsissp. acbc2 isolated from theChinese mangrove plantAegiceras corniculatum.Journal of Antibiotics,2014, 67(6), 451-457.

  144. Wang J, Lin X, Qin Z, Liao S, Wan J, Zhang T, Liu J, Fredimoses M, Chen H, Yang Y, Zhou X, Yang X, Tu Z,Liu Y*. Antimicrobial and antiviral sesquiterpenoids from sponge-associated fungus,Aspergillus sydowii ZSDS1-F6. Journal of Antibiotics,2014,67(8), 581-583.

  145. Liao S, Qin C,Yao P, Li J, Zhou X,Wang J, Huang Z,Liu Y*.A one-pot synthesis of unsaturated, polysubstituted 3-aminoazepan-2-ones.Synthesis2014, 46(5), 621-628.

  146. Yang X, Li S, Li Y, Feng L, Shen Y, Lin S, Tian J, Zeng H, Wang N, Steinmetz A,Liu Y, Zhang W*.Chemical constituents ofAbies delavayi.Phytochemistry, 2014, 105, 164-170.  

  147. Peng Y, Huang R, Hu J, Zhou X, Yang B, Liu L, Yang X,Liu Y*. Bioactive chemical constituents of the South China Sea starfishStellaster equestris.Chemistry of Natural Compounds, 2014, 50(1), 184-185.

  148. Huang R, Yan T, Peng Y, Zhou X, Yang X,Liu Y*. Diketopiperazines from the marine spongeAxinella sp.Chemistry of Natural Compounds, 2014, 50(1), 191-193.

  149. Wang J, Xu F, Wang Z, Lu X, Wan J, Yang B, Zhou X, Zhang T, Tu Z,Liu Y*.A new naphthalene glycoside from the sponge-derived fungusArthrinium arundinis ZSDS1-F3.Natural Product Research,2014, 28(14), 1070-1074.

  150. Yang B, Dong J, Lin X, Tao H, Zhou ZLiu Y*. Xylaolide A,a newlactone from the fungusXylariaceae sp. DPZ-SY43.Natural Product Research,2014,28(13), 967-970.

  151. Zhou X, Sun J, Ma W, Fang W, Chen Z, Yang B,Liu Y*. A new aromatic amine from fungusPestalotiopsis vaccinii.Phytochemistry Letters,2014, 7, 35-37.

  152. Zhou X, Sun J, Ma W, Fang W, Chen Z, Yang B,Liu Y*. Bioactivities of six sterols isolated from marine invertebrates.Pharmaceutical Biology, 2014, 52(2), 187-190.

  153. Yang B, Tao H,Zhou X, Lin X,Liu Y*.Two new alkaloids from marine spongeCallyspongiasp. Natural Product Research, 2013,27(4-5),433-437.

  154. Yang B, Liao S, Lin X, Wang J, Liu J, Zhou X, Yang X,Liu Y*.New sinularianin sesquiterpenes from soft coral Sinularia sp.Marine Drugs, 2013, 11, 4747-4750.

  155.  Sun J, Han Z, Zhou X, Yang Y, Lin X, Liu J, Peng Y, Yang X,Liu Y*. Antifouling briarane type diterpenoids from South China Sea gorgoniansDichotella gemmaceaTetrahedron 2013, 69, 971-880.

  156.  Zhou X, Liu J, Yang B, Lin X, Yang X,Liu Y*. Marine natural products with anti-HIV activities in the last decade. Current Medicinal Chemistry, 2013, 20(7), 953-973.

  157. Yang X, Zhang G, Ying J, Yang B, Zhou X, Steinmetz A,Liu Y*.Wang N*.Isolation, characterization, and bioactivity evaluation of 3-((6-methylpyrazin-2-yl) methyl)-1H-indole, a new alkaloid from a deep-sea-derivated actinomyceteSerinicoccus profundisp. nov.Marine Drugs,2013, 11, 33-39.

  158. Huang RM, Peng Y, Zhou XF, Yang X,Liu Y*.A new taurine derivative from South China Sea marine spongeAxinella sp.Natural Product Research, 2013,27(17),1537-1541.

  159. Huang R, Peng Y, Zhou X, Fu M, Tian S,Liu Y*. A new pyrimidinedione derivative from the gorgonian coralVerrucellaumbraculum.Natural Product Research, 2013,27(4-5),319-322.

  160. Zhou X, Lin X, Guo X, Yang Y, Yang X,Liu Y*.Chemical constituents of the spongeMycalespecies from South China Sea.Records of Natural Products, 2013,7, 119-123.

  161. Yang B, Zhou X, Huang H, Yang X, Liu J, Lin X, Li X, Peng Y,Liu Y*.New cembrane diterpenoids from a Hainan soft coralSinulariasp.Marine Drugs,2012, 10, 2023-2032.

  162. Yang B, Zhou X, Lin X, Liu J, Peng Y, Yang X, Liu Y*.Cembrane diterpenes chemistry and biological properties.Current Organic Chemistry,2012, 16(12), 1512-1539.

  163. ChenJ, Lan X,LiuY*, Jia A*.In vitro effects of natural diketopiperazines on release of cytokines and chemokines in J774A.1 macrophages.Bioorganic Medicinal ChemistryLetter,2012, 16, 3177-3180.

  164. LinX, ZhouX, WangF, LiuK, YangB, YangX,Peng P, Liu L,RenZ,LiuY*.Anewcytotoxicsesquiterpenequinoneproduced byPenicillium sp. F00120isolated from adeepseasedimentsample.Marine Drugs,2012, 10, 106-115.

  165. Kim E, Li J, Dang H, Hong J, Lee C, Kim D, Yoon W, Kim E,Liu Y, Jung J*.Cytotoxic cytochalasins from the endozoic fungusPhoma sp. of the giant jellyfishNemopilema nomurai.Bioorganic & Medicinal Chemistry Letters, 2012, 22, 3126–3129.

  166. Li W, Wang L, Zhao D,Liu Y*. Steroidal alkaloids fromVeratrum nigrum L.Chemistry of Natural Compounds, 2012, 48(5), 919-920.

  167. He WH, Lin L, Xu T, Jung JH, Yin H, Yang B,Liu Y*. A new norsesterterpenoid from the sponge speciesSarcotragus.Chemistry of Natural Compounds, 2012, 48(2), 208-210.

  168. Peng Y, Xie E, Zheng K, Fredimoses M, Yang Y, Zhou X, Wang Y, Yang B, Lin X, Liu J,Liu Y*.Nutritional and chemical composition and antiviral activity of cultivated seaweedSargassum naozhouense Tseng et Lu.Marine Drugs,2013, 11, 20-32.

  169. Huang R, Wang B,Liu Y*.Briarane-type diterpenoids from the gorgonian coralVerrucella umbraculum.Chemistry of Natural Compounds,2012, 48(3), 516-517.

  170. Yang B, Hu J, Lei H, Chen XC, Zhou XF,Liu Y*. Chemical constituents of marine sponge Callyspongia sp. from the South China Sea.Chemistry of Natural Compounds,2012, 48(2), 350-351.                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        

  171. Liao X,Tang L, Liang Y, Jian S,Xu S,Liu Y*.New pentahydroxylated steroids from the South China Sea gorgonianSubergorgia suberosa. Chemistry & Biodiversity, 2012,9, 370-375.

  172. Liu Y*.Renaissance of marine natural product drug discovery and development.Journal of Marine Science Research & Development,2012, 2, 1000e106.

  173. Sun J, Huang H, Chai X, Yang X, Meng L, Huang C, Zhou X, Yang B, Hu J, Chen X, Lei H, Wang L,Liu Y*. Dichotellides A-E, five new iodine-containing briarane type diterpenoids fromDichotella gemmacea.Tetrahedron, 2011, 67, 1245-1250.

  174. Wang L, Zhao D, Di L, Xu T, Lin X, Yang B, Zhou X, Yang X,Liu Y*. The analgesic and anti-rheumatic effects ofThladiantha dubia fruit crude polysaccharide fraction in mice and rats.Journal of Ethnopharmacology,2011,137, 1381-1387.

  175. Zhou X, Lu Y, Lin X, Yang Y, Yang X,Liu Y*.Brominated aliphatic hydrocarbons and sterols from the spongeXestospongia testudinaria with their bioactivities.Chemistry and Physics of lipids,2011,164, 703-706.

  176. Yang X, Li Y, Li S, Shen Y, Tian J, Zhu Z, Feng L, Wu, L, Lin, S, Wang, N,Liu Y, Zhang W*. Mono- and sesquiterpenoids, flavonoids, lignans, and other miscellaneous compounds ofAbies georgei.Planta Medica, 2011, 77(7), 742-748.

  177. Wang L, Zhao D,Di L, Cheng D,Zhou X, Yang X,Liu Y*. The anti-hyperplasiaofmammaryglandeffectofThladiantha dubia root ethanol extract inratsreducedbyestrogenandprogestogen.Journal of Ethnopharmacology,2011,134, 136-140.

  178. Yang X, Dong G, Zhou X, Chai X, Li Y, Yang B, Zhang W,Liu Y*.Isolation and structural characterisation of five new and 14 known metabolites from the commercial starfishArchaster typicus Food Chemistry,2011,124, 1634-1638.

  179. Liu Y*, Yan H, Wen K, Zhang J, Xu T, Wang L, Zhou X, Yang X. Identification of epidioxysterol from South China Sea urchinTripneustes gratilla Linnaeus and its cytotoxic activity.Journal of Food Biochemistry, 2011, 35, 932-938.

  180. Hu J, Yang B, Lin X, Zhou X, Yang X, Long L,Liu Y*.Chemical and biological studies of soft coralsNephtheidae family.Chemistry &Biodiversity, 2011, 8,1011-1032.

  181. Dong G, Yang X, Zhou X.Liu Y*.Chemical constituents and bioactivities of starfish.Chemistry & Biodiversity, 2011, 8(5), 740-791.

  182. Huang R, Zhou X, Peng Y, Yang X, Xu T, Liu Y*.Nucleosides from the marine spongeCallyspongiasp.Chemistry of Natural Compounds,2011, 46, 1010-1011.

  183. Liu Y*, Jung J, Xu T, Long LJ, Lin XP, Yin H., Yang B, Zhou XF, Yang XW. New cyclitol derivative from a spongeSarcotragusspecies.Natural Products Research,2011, 25(6), 648-652.

  184. Chai X, Sun J, Tang L, Yang X, Li Y, Huang H, Zhou X, Yang B,Liu Y*. A novel cyclopentene derivative and a polyhydroxylated steroid from a South China Sea gorgonianMenellasp.Cheimcal & Pharmaceutical Bulletin,2010, 58(10), 1391-1394.

  185. Liu J, Wang L, Zhao D, Cheng D, Xu T, Zhou X, Yang X,Liu Y*. A new lignan fromSaururus chinensis.Chemistry of Natural Compounds,2010, 46(4), 631-632.

  186. Zhou X, Xu T, Yang X, Xu S,Liu Y*.Chemical and biological aspects of marine sponge of the genusXestospongia.Chemistry & Biodiversity,2010, 7, 2201-2227.

  187. Wang L, Zhou X, Xu T, Yang X,Liu Y*. Lignans fromSaururus chinensis.Chemistry of Natural Compounds, 2010, 46(3), 451-452.

  188. Peng Y, Zheng J, Huang R, Wang Y, Xu T, Zhou X, Liu Q, Zeng F, Ju H, Yang X,Liu Y*.Polyhydroxysteroids and saponins from the China Sea starfishAsterina sp. and their biological activities.Chemical & Pharmaceutical Bulletin, 2010, 58(6), 856-858.

  189. Zhou X*, Liu Y, Tang L, Zhang P, Wu J. Chemical constituents from the roots ofActinidia chinensis.Chemistry of Natural Compounds,2010, 46(2), 308-309.

  190. Huang L, Wen K, Gao X,Liu Y*. Hypolipidemic effect of fucoidan fromLaminaria japonica in hyperlipidemic rats.Pharmaceutical Biology,2010,48(4), 422-426.

  191. Huang R, Ma W, Dong J, Zhou X, Xu T, Lee K,Yang X, Xu S,Liu Y*. A new 1,4-diazepine from South China Sea marine spongeCallyspongiaspecies.Molecules,2010, 15, 871-877.

  192. Yang X, Li S, Wu L, Li Y, Feng L, Shen Y, Tian J, Tang J, Wang N,Liu Y, Zhang W*. Abiesatrines A-J: anti-inflammatory and anti-tumor triterpenoids fromAbies georgei Orr.Organic & Biomolecular Chemistry,2010, 8, 2609-2616.

  193. Ren S, Ma W, Xu T, Lin X, Yin H, Yang B, Zhou X, Yang X, Long L, Lee K, Gao Q,Liu Y*. Two novel alkaloids from the South China Sea marine spongeDysideasp. Journal of Antibiotics,2010,63, 699-701.

  194. Huang R, Zhou X, Xu T, Yang X,Liu Y*.Diketopiperazines from marine organisms.Chemistry & Biodiversity,2010,7, 2809-2829.

  195. Yang X, Li S, Li Y, Xia J, Wu L, Shen Y, Tian J, Wang N,Liu Y, Zhang W. Abiespiroside A, an unprecedented sesquiterpenoid spirolactone with a 6/6/5 ring system fromAbies delavayi.European Journal of Organic Chemistry,2010, 34, 6531-6534.  

  196. Xu Y,Liu Y, Xu T, Xie S, Si Y, Liu Y, Zhou H, Liu T, Xu D.A new furostanol glycoside fromTribulus terrestris.Molecules,2010,15,613-618.

  197. Xu Y, Bai L,Liu Y, Xu T, Liu Y, Xie S, Si Y, Zhou H, Liu T, Xu D. A new triterpenoid saponin fromPulsatilla cernua.Molecules, 2010, 15, 1891-1897.

  198. Lei H, Zhou X, Yang Y, Xu T, Yang X, Sun J, Yang Y, Hu J, Lin X, Long L,Liu Y*.Bryostatins from South China Sea bryozoanBugula neritina L.Biochemical Systematics and Ecology,2010,38, 1231-1233.

  199. Zhou X, Wen K, Yang X, Huang R, Dong G, Yang B, Sun J,Liu Y*. Chemical constituents from the sea urchinGlyptocidaris crenularis.Biochemical Systematics and Ecology,2010, 38, 103-105.

  200. Yang X, Feng L, Li S, Liu X, Li Y, Wu L, Shen Y, Tian J, Zhang X, Liu X, Wang N,Liu Y, Zhang, W*.Isolation, structure, and bioactivities of abiesadines A–Y, twenty-five new diterpenes fromAbies georgeiOrr.Bioorganic Medicinal Chemistry, 2010,18, 744-754.

  201. Wang L, Cheng D, Wang H, Di L, Zhou X, Xu T, Yang X,Liu Y*.The hepatoprotective and antifibrotic effects ofSaururus chinensis against carbon tetrachloride induced hepatic fibrosis in rats.Journal of Ethnopharmacology, 2009, 126, 487-491.

  202. Wang L, Zhao D, Xu T, Zhou X, Yang X,Liu Y*. A new triterpene hexaglycoside from the bark ofKalopanax septemlobus(Thunb.) Koidz.Molecules,2009,14, 4497-4504.

  203. Zhou X*, Tang L, Liu Y. An isomeric mixture of novel cerebrosides isolated fromImpatiens pritzellii reduces lipopolysaccharide-induced release of IL-18 from human peripheral blood mononuclear cells.Lipids, 2009, 44(8), 759-763.

  204. Zhou X, Tang L, Zhang P, Zhao X, Pi H, Zhang Y, Ruan H,Liu Y, Wu J*. The interleukin-18 inhibitory activities of echinocystic acid and its saponins fromImpatiens pritzellii var. hupehensis.Zeitschrift Fur Naturforschung,2009, 64c, 369-372.

  205. Wang L, Zhao D,Liu Y*. GC-MS analysis of the supercritical CO2 fluid extraction ofEphedrasinica roots and its antisudorific activity.Chemistry of Natural Compounds,2009, 45(3), 434-436.

  206. Wang B, Dong J, Zhou X, Lee KJ, Huang R, Zhang S,Liu Y*. Nucleosides from marine sponges including known ones fromHaliclona sp.Zeitschrift Fur Naturforschung,2009, 64c, 143-148.

  207. Wang B, Lee K, Zhang S, Jung J,Liu Y*. 2-Palmitamidoethanesulfonic acid, new aminoethylsulfonic acid derivative from marine spongeHaliclona sp.Chemistry of Natural Compounds,2009, 45(1), 137-138.

  208. Yang B, Dong J, Zhou X, Yang X, Lee K, Wang L, Zhang S,Liu Y*. Proline-containing dipeptides from the marine sponge aCallyspongia species.Helvetica Chimica Acta,2009, 92, 1112-1117.

  209. Zhou X, Xu T, Wen K, Yang X, Xu S,Liu Y*.A newN-acyl taurine from the sea urchinGlyptocidaris crenularis.Bioscience, Biotechnology and Biochemistry,2009, 74(5), 1089-1091.

  210. Liu Y, Abreu P. Tirucallane triterpenes from the roots ofOzoroa insignis.Phytochemistry, 2006, 67,1309-1315.

  211. Liu Y, Mansoor T,Hong J, Lee C, Sim C, Im K, Jung J.New cytotoxic sesterterpenoids and norsesterterpenoids from twosponges of the genusSarcotragus.Journalof Natural Products, 2003, 66(11),1451-1456.

  212. Liu Y, Hong J, Lee C, Im KS,Kim N, Choi J, Jung J.Newcytotoxicfurano- andpyrroloterpenoids from thespongeSarcotragusspecies.Journalof Natural Products, 2002, 65(9),1307-1314.

  213. Liu Y, Bae B, Alam N, Hong J, Sim C, Lee C, Im K,Jung J.New cytotoxic sesterterpenes from the spongeSarcotragus species.Journalof Natural Products, 2001, 64(10), 1301-1304.

  214. Tao H, Wang L, Cui Z, Zhao D,Liu Y*.Dimeric proanthocyanidins from rootsofEphedra sinica Stapf.Planta Medica, 2008, 74, 1823-1825.

  215. Liu Y, Lee C, Hong, J, Jung J.Cyclitolderivatives from thespongeSarcotragusspecies.Bulletinofthe Korean Chemical Society, 2002, 23(10),1467-1469.

  216. Liu Y*, Jung J, Zhang S. Linear pyrrolosesterterpenes from a spongeSarcotragus species.Biochemical Systematics and Ecology, 2006, 34, 774-776.

  217. Park Y, Liu Y, Hong J, Lee C, Cho H, Kim D, Im K,Jung J.Newbromotyrosinederivatives from anassociation oftwosponges,Jaspis wondoensis andPoecillastra wondoensis. Journalof Natural Products, 2003, 66(11),1495-1498.

  218. Wang L, Zhao D, Cheng D,Liu Y*.ent-Sauchinone fromSaururus chinensis.Heterocycles, 2008, 75(5), 1241-1246.

  219. Wang W, Li F, Alam N,Liu Y, Hong J, Lee C, Jung J.Newsaponins from thestarfishCertonardoa semiregularis.Journalof Natural Products, 2002, 65(11),1649-1656.

  220. Liu Y*, Jung J,JiH, ZhangS. Glycerolipids from aSarcotragusspeciessponge.Molecules,2006,11, 714-719.

  221. Liu Y*, Ji H, Zhang S, Jung J, Xu T.Trisoxazole macrolides from the spongeSarcotragusspecies.Chemistry of Natural Compounds,2008, 44(1), 140-141.

  222. Abreu P*,Liu Y.Ozoroalide, a new macrolide fromOzoroa insignis.Fitoterapia,2007, 78, 388-389.

  223. Yin H, Zhang S*, Luo X,Liu Y. Preparative isolation and purification of two benzoxazinoid glucosides fromAcanthus ilicifoliusL. by high-speed counter-current chromatography.Journal of Chromatography A,2008, 1205, 177-181.

  224. Wang L, Zhao D,Liu Y*. Quality assessment ofVeratrum nigrum L. by LC-ELSD fingerprints and LC quantitative analysis.Chromatographia, 2008, 68, 961-967.

  225. Liu Y*, Murakami N, Wang L, Zhang S.Preparative high-performance liquid chromatography for the purification of natural acylatedanthocyanins from red radish (Raphanus sativus L).Journal of Chromatographic Science, 2008, 46(8), 743-746.

  226. Liu Y*, Ji H, Dong J, Zhang S. Lee K, Matthew S.Antioxidantalkaloid from South China SeamarinespongeIotrochota sp. Zeitschrift Fur Naturforschung,2008, 63c, 636-638.

  227. Wang L, Li W,Liu Y*.Hypotensive effect and toxicology of total alkaloids and veratramine from roots and rhizomes ofVeratrum nigrum L. in spontaneously hypertensive rats.Pharmazie, 2008, 63(8), 606-610.

  228. Jiang S, Li X, Zhang L, Sun W, Dai S, Xie L,Liu Y, Lee K. Culturable actinobacteria isolated from marine spongeIotrochota sp.Marine Biology, 2008, 153(5), 945-952.

  229. Jiang S,Sun W,Chen M,Dai S,Zhang L,Liu Y,Lee K,Li X.Diversity of culturable actinobacteria isolated from marine spongeHaliclona sp.Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology,2007, 92(4), 405-416.

  230. Liu Y*, Ji H, Zhang S, Murakami N, Xu T. Structure-activity relationships of1'-acetoxychavicol acetate homologues as new nuclear export signal inhibitors.Pharmazie2007, 62(9), 659-662.

  231. Liu Y*, Zhang S,Jung J, Xu T.Variabilin, a chemotaxonomic marker for the familly Irciniidae.Zeitschrift Fur Naturforschung,2007, 62c, 473-476.

  232. Jung J*, Shinde P, Hong J,Liu Y, Sim C. Secondary metabolites from a marine spongeDiscodermia calys.Biochemical Systematics and Ecology,2007, 35,48-51.

  233. Liu Y*, Murakami N, AbreuP, Ji H, Zhang S. Antimalarial flavonol glycosides fromEuphorbia hirta.Pharmaceutical Biology, 2007, 45(4), 278-281.

  234. Liu Y*, Jung J, Zhang S. An unsaturated ω-hydroxy methyl ester from a spongeSarcotragus species.Chemistry of Natural Compounds, 2006, 42(4), 487-488.

  235. Liu Y, Abreu P*. Long chain alkyl and alkenyl phenols fromOzoroa insignis.Journalofthe Brazilian Chemical Society, 2006, 17(3),527-536.

  236. Liu Y*, Jung J, Zhang S. Indole alkaloids from a spongeSarcotragus species.Biochemical Systematics and Ecology, 2006, 34(5), 453-456.

  237. Liu Y, Shinde PB, Hong J, Lee C-O, Im KS, Jung JH*. Trisoxazole macrolide from a marine sponge Sarctragus species.Natural Product Sciences, 2005, 11(1), 50-53.

  238. Zhao Q,Liu Y, Hong J, Lee C-O, Park JH, Lee DS, Jung JH. A new cyclitol derivatives from a sponge Stelletta species.Natural Product Sciences, 2003, 9(1), 18-21.


Patents
Issued Patent
1. Preparation Method and Applications of Cyclitol from Marine Sponge Sarcotragus. Patent No: ZL200610035618.7, Inventors: Yonghong Liu
2. Preparation Method and Applications of Norsestertepenoid from Marine Sponge Sarcotragus. Patent No: ZL200610035603.0, Inventors: Yonghong Liu
3. Preparation Method of Antihyptensive Marine Drug and Dispersing Tablet. Patent No: ZL200610124326.0. Inventors: Yonghong Liu
4. Preparation Method and Pharmaceutical Applications of Saururus Chinensistotal Active Fraction. Patent No: ZL200710055422.9. Inventors: Yonghong Liu
5. Preparation Method and Anticancer Applications of Sea Urchin Extract. Patent No: ZL200710032474.4. Inventors: Yonghong Liu
6. Preparation Method and Anticancer Applications of Diflavonoids. Patent No: ZL200710032476.3. Inventors: Yonghong Liu 
7. A marine drug for Mammary Hyperplasia. Patent No: ZL201110137130.6 Inventors: Yonghong Liu

Research Interests

Marine organisms are plentiful source of bioactive lead compounds. They are subjects of intensive screening program for new drug leads. Our research interests are discovery of antitumor and antifouling compounds from marine invertebrates and the microorganisms isolated from invertebrates.
Our main research activities include:
1. Collection of invertebrates by SCUBA diving
2. Isolation of fungi and bacteria from the collected invertebrates
3. Mass culture of the microorganisms
4. Chemical analysis of the active components of the invertebrates and marine-derived microorganisms
5. Simple ‘Bench-top’ screening systems including brine shrimp assay, antimicrobial assay, DPPH assay, bioautographic TLC, ELISA assay
6.Synthesis of biologically-active secondary metabolites from marine invertebrates.

Students

已指导学生

董光  硕士研究生  070703-海洋生物学  

黄日明  博士研究生  070702-海洋化学  

杨斌  博士研究生  070702-海洋化学  

孙见凡  博士研究生  070702-海洋化学  

胡静  硕士研究生  070702-海洋化学  

连喜平  博士研究生  070703-海洋生物学  

白志强  硕士研究生  070702-海洋化学  

钟志龙  硕士研究生  070702-海洋化学  

冼嘉韵  硕士研究生  070702-海洋化学  

艾文  博士研究生  070702-海洋化学  

李晋昇  硕士研究生  070702-海洋化学  

汤勇  硕士研究生  070702-海洋化学  

田永奇  博士研究生  070702-海洋化学  

戴昱  硕士研究生  070702-海洋化学  

庞小艳  博士研究生  070702-海洋化学  

郭翠  硕士研究生  070703-海洋生物学  

罗小卫  博士研究生  070703-海洋生物学  

现指导学生

陈伟豪  博士研究生  070703-海洋生物学  

李坤龙  博士研究生  070703-海洋生物学  

宋莹莹  硕士研究生  070703-海洋生物学  

龙洁怡  博士研究生  070703-海洋生物学  

王佳敏  硕士研究生  070703-海洋生物学  

陈春梅  博士研究生  070703-海洋生物学  

Postdoctoral position

Postdoctoral position - Marine Natural Product Chemistry
A postdoctoral position will shortly be available in the Guangdong Key Laboratory of Marine Materia Medica, at South China Sea Institute of Oceanology, Chinese Academy of Sciences in Guangzhou, China, working with Dr. Yonghong Liu in the area of Marine Natural Product Chemistry.
Essential qualifications:
Applicants must have a Ph. D. in Medicinal Chemistry, Synthesis, Natural Products Chemistry, microbiology, Pharmacognosy or a related field. The position requires experience in the isolation and structure elucidation of natural products. The position requires proficiency in nuclear magnetic resonance (NMR) and high performance liquid chromatography (HPLC) techniques, and in the interpretation of the resulting data. Other important abilities are the uses of various types of chromatography to achieve purification of natural products and the ability to work independently. This is a two-year appointment.
Salary: about 250000- 450000RMB/year.
Description of Duties:
Bioassay-guided fractionation of natural product extracts (marine organism), isolation, and structure determination of active molecules by using chromatographic and spectral methods. Opportunities to help instruct students in natural product-related techniques.
The application should include a detailed resume, a list of publications, and contact information for at least three references. Applications (as well as requests for additional information) should be sent, preferably by e-mail, to:
Dr. Yonghong Liu,yonghongliu@scsio.ac.cn
Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510-301, China

 This recruitment is open year-round


International PhD Positions

International PhD Position- Marine Natural Product Chemistry
A International PhD Position will shortly be available in the Guangdong Key Laboratory of Marine Materia Medica, at South China Sea Institute of Oceanology, Chinese Academy of Sciences in Guangzhou, China, working with Dr. Yonghong Liu in the area of Marine Natural Product Chemistry.
Essential qualifications:
Applicants must have a Master degree. in Medicinal Chemistry, Synthesis, Natural Products Chemistry, microbiology, Pharmacognosy or a related field. The position requires experience in the isolation and structure elucidation of natural products. The position requires proficiency in nuclear magnetic resonance (NMR) and high performance liquid chromatography (HPLC) techniques, and in the interpretation of the resulting data. Other important abilities are the uses of various types of chromatography to achieve purification of natural products and the ability to work independently. This is a three-five year appointment.
Salary: about 5000 RMB per month.
Description of Duties:
Bioassay-guided fractionation of natural product extracts (marine organism), isolation, and structure determination of active molecules by using chromatographic and spectral methods. Opportunities to help instruct students in natural product-related techniques.
The application should include a detailed resume, a list of publications, and contact information for at least three references. Applications (as well as requests for additional information) should be sent, preferably by e-mail, to:
Dr. Yonghong Liu,yonghongliu@scsio.ac.cn
Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510-301, China
This recruitment is open year-round

International Master students

International Master student- Marine Natural Product Chemistry
A International Master student Position will shortly be available in the Guangdong Key Laboratory of Marine Materia Medica, at South China Sea Institute of Oceanology, Chinese Academy of Sciences in Guangzhou, China, working with Dr. Yonghong Liu in the area of Marine Natural Product Chemistry.
Essential qualifications:
Applicants must have a bachelor degree. in Medicinal Chemistry, Synthesis, Natural Products Chemistry, microbiology, Pharmacognosy or a related field. The position requires experience in the isolation and structure elucidation of natural products. The position requires proficiency in nuclear magnetic resonance (NMR) and high performance liquid chromatography (HPLC) techniques, and in the interpretation of the resulting data. Other important abilities are the uses of various types of chromatography to achieve purification of natural products and the ability to work independently. This is a three-year appointment.
Salary: about 2000RMB per month.
Description of Duties:
Bioassay-guided fractionation of natural product extracts (marine organism), isolation, and structure determination of active molecules by using chromatographic and spectral methods. Opportunities to help instruct students in natural product-related techniques.
The application should include a detailed resume, a list of publications, and contact information for at least three references. Applications (as well as requests for additional information) should be sent, preferably by e-mail, to:
Dr. Yonghong Liu,yonghongliu@scsio.ac.cn
Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510-301, China
This recruitment is open year-round

Group member

Professor: Dr.  Xuefeng Zhou

Associate Professor: Dr.  Bin Yang, Junfeng Wang, Xiuping Lin,  Shengrong Liao,
Assistant Professor: Dr. Xiaoyan Pang