研究领域主要包括: 蓝藻毒素分子毒理学、蓝藻毒素生物学功能及蓝藻毒素的防御及控制.

    主要招收有生物化学或微生物学研究背景的本届或应届毕业生。 

招生专业： 水生生物学
招生方向： 蓝藻生物毒素学
                   蓝藻生物化学

071004-水生生物学

   

-- 研究生

-- 博士

   

2011-06--2011-12 University of California at Riverside 访问研究
2007-10--2009-04 Georgetown University 访问研究

   

[1] 甘南琴, 宋立荣, 陈莉婷. 具有溶藻活性的假单胞菌及其应用. CN: CN111471609B, 2022-03-15.
[2] 宋立荣, 戴国飞, 甘南琴, 陈伟. 一种去除微囊藻毒素改良活性炭及制备方法. CN: CN102580677A, 2012-07-18.
[3] 宋立荣, 戴国飞, 甘南琴, 全昌云, 张先正. 一种去除微囊藻毒素凝胶离子材料及制备方法. CN: CN102247816A, 2011-11-23.
[4] 宋立荣, 刘梅, 甘南琴, 李林, 陈伟, 李阔宇. 一种毒微囊藻培养的方法. 中国: CN1234843, 2006-01-04.
[5] 宋立荣, 刘梅, 甘南琴, 李林, 陈伟, 李阔宇. 一种高产毒微囊藻培养的方法. CN: CN1563344A, 2005-01-12.
[6] 宋立荣, 潘卉, 翟超, 甘南琴, 刘永定. 一种检测微囊藻产毒的方法. CN: CN1428434A, 2003-07-09.
[7] 宋立荣, 沈强, 陈伟, 甘南琴, 何振荣, 刘永定, 雷腊梅. 一种微囊藻毒素的提取纯化方法. CN: CN1401660A, 2003-03-12.

   

[1] 曾佳颖, 江婧宇, 左俊, 甘南琴. 不同无机碳转运基因型蓝藻对环境CO2变化的响. 水生生物学报[J]. 2023, 47(7): 1069-1076, [2] 左俊, 曾佳颖, 杨丝雨, 宋立荣, 甘南琴. 藻类连续培养体系的构建与优化及其在产毒和无毒微囊藻竞争中的应用. 水生生物学报[J]. 2022, 46(7): 1060-1069, http://lib.cqvip.com/Qikan/Article/Detail?id=7107679734.
[3] Zuo, Jun, Hu, Lili, Shen, Wei, Zeng, Jiaying, Li, Lin, Song, Lirong, Gan, Nanqin. The involvement of alpha-proteobacteria Phenylobacterium in maintaining the dominance of toxic Microcystis blooms in Lake Taihu, China. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(2): 1066-1078, https://www.webofscience.com/wos/woscc/full-record/WOS:000587696600001.
[4] Wei, Nian, Song, Lirong, Gan, Nanqin. Quantitative Proteomic and Microcystin Production Response of Microcystis aeruginosa to Phosphorus Depletion. MICROORGANISMS[J]. 2021, 9(6): http://dx.doi.org/10.3390/microorganisms9061183.
[5] 陈莉婷, 左俊, 宋立荣, 刘津, 甘南琴. 溶藻细菌筛选及溶藻活性物质对铜绿微囊藻生理活性的影响. 水生生物学报[J]. 2020, 44(3): 638-, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2020&filename=SSWX202003024&v=MDAwNDFyQ1VSN3FlWitSdkZpemtWNzdQTmo3Y2RyRzRITkhNckk5SFlJUjhlWDFMdXhZUzdEaDFUM3FUcldNMUY=.
[6] Siyi Tao, Suqin Wang, Lirong Song, Nanqin Gan. Understanding the Differences in the Growth and Toxin Production of Anatoxin-Producing Cuspidothrix issatschenkoi Cultured with Inorganic and Organic N Sources from a New Perspective: Carbon/Nitrogen Metabolic Balance. TOXINS[J]. 2020, 12(724): https://doaj.org/article/1497dc7458134ca4ab8a3672f8a20399.
[7] 甘南琴. 鱼腥藻毒素HPLC-PDA和UPLC-MS/MS检测方法的比较研究. 食品安全质量检测学报. 2020, [8] 陶思依, 左俊, 陈莉婷, 甘南琴, 宋立荣, 戴国飞. 利用微生物控制蓝藻的研究进展. 武汉大学学报(理学版)[J]. 2019, 401-410, http://ir.ihb.ac.cn/handle/342005/30858.
[9] 甘南琴. Assessment of different mcy genes for detecing the toxic to non-toxic Microcystis ratio in the field by multiplex qPCR. Journal of Oceanology and Limnology. 2018, [10] Zhao, Liang, Song, Yulong, Li, Lin, Gan, Nanqin, Brand, Jerry J, Song, Lirong. The highly heterogeneous methylated genomes and diverse restriction-modification systems of bloom-forming Microcystis. HARMFUL ALGAE[J]. 2018, 75(1): 87-93, http://ir.ihb.ac.cn/handle/342005/34521, http://www.irgrid.ac.cn/handle/1471x/6853831, http://ir.ihb.ac.cn/handle/342005/34522, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000438969100008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[11] Ding Yi, Gan Nanqin, Liu Jin, Zheng Lingling, Li Lin, Song Lirong. Survival, recovery and microcystin release of Microcystis aeruginosa in cold or dark condition. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2017, 35(2): 313-323, http://dx.doi.org/10.1007/s00343-016-5215-x.
[12] 魏念, 甘南琴, 宋立荣. 微囊藻毒素生物学功能研究进展. 湖泊科学[J]. 2017, 29(1): 1-8, http://lib.cqvip.com/Qikan/Article/Detail?id=671055247.
[13] 甘南琴. Microcystin-degrading bacteria affect mcyD expression and microcystin synthesis in Microcystis sppl. J Environ Sci (China). 2016, [14] Wei, Nian, Hu, Lili, Song, Lirong, Gan, Nanqin. Microcystin-Bound Protein Patterns in Different Cultures of Microcystis aeruginosa and Field Samples. TOXINS[J]. 2016, 8(10): https://doaj.org/article/7ef8680ec284406c9ecf3b8ad4eafdca.
[15] Hu, Lili, Shan, Kun, Lin, Lizhou, Shen, Wei, Huang, Licheng, Gan, Nanqin, Song, Lirong. Multi-Year Assessment of Toxic Genotypes and Microcystin Concentration in Northern Lake Taihu, China. TOXINS[J]. 2016, 8(1): http://ir.ihb.ac.cn/handle/342005/27945.
[16] Wang, Suqin, Zhu, Lin, Li, Qi, Li, Genbao, Li, Lin, Song, Lirong, Gan, Nanqin. Distribution and population dynamics of potential anatoxin-a-producing cyanobacteria in Lake Dianchi, China. HARMFUL ALGAE[J]. 2015, 48: 63-68, http://dx.doi.org/10.1016/j.hal.2015.07.005.
[17] Zhu, Lin, Wu, Yanlong, Song, Lirong, Gan, Nanqin. Ecological Dynamics of Toxic Microcystis spp. and Microcystin-Degrading Bacteria in Dianchi Lake, China. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2014, 80(6): 1874-1881, http://www.irgrid.ac.cn/handle/1471x/852692.
[18] 甘南琴. Fast removal of cyanobacterial toxin MC-LR by low-cytotoxic microgel-Fe3+ complex. Water Research. 2012, [19] 甘南琴. Enhancement of colony formation in bloom-forming Cyanobacterium Microcystis spp. by Microcystin-RR via induction of exopolysaccharides. Environmental Microbiology. 2012, [20] Sun, Xiaoyun, Mi, Lixin, Liu, Jin, Song, Lirong, Chung, FungLung, Gan, Nanqin. Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2011, 255(1): 9-17, http://dx.doi.org/10.1016/j.taap.2011.05.011.
[21] Gan, Nanqin, Sun, Xiaoyun, Song, Lirong. Activation of Nrf2 by Microcystin-LR Provides Advantages for Liver Cancer Cell Growth. CHEMICAL RESEARCH IN TOXICOLOGY[J]. 2010, 23(9): 1477-1484, http://ir.ihb.ac.cn/handle/342005/13773.
[22] Gan, Nanqin, Mi, Lixin, Sun, Xiaoyun, Dai, Guofei, Chung, FungLung, Song, Lirong. Sulforaphane protects Microcystin-LR-induced toxicity through activation of the Nrf2-mediated defensive response. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2010, 247(2): 129-137, http://dx.doi.org/10.1016/j.taap.2010.06.005.
[23] Lixin Mi, Nanqin Gan, Amrita Cheema, Sivanesan Dakshanamurthy, Xiantao Wang, David CH Yang, FungLung Chung. Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes. JOURNAL OF BIOLOGICAL CHEMISTRY. 2009, 284(25): 17039-17051, http://dx.doi.org/10.1074/jbc.M901789200.
[24] Hu, Chenlin, Gan, Nanqin, Chen, Yuanyuan, Bi, Lijun, Zhang, Xianen, Song, Lirong. Detection of microcystins in environmental samples using surface plasmon resonance biosensor. TALANTA[J]. 2009, 80(1): 407-410, http://dx.doi.org/10.1016/j.talanta.2009.06.044.
[25] Mi, Lixin, Gan, Nanqin, Chung, FungLung. Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2009, 388(2): 456-462, https://www.webofscience.com/wos/woscc/full-record/WOS:000274534300051.
[26] Gan Nanqin, Wu Yu-Chieh, Brunet Mathilde, Garrido Carmen, Chung Fung-Lung, Dai Chengkai, Mi Lixin. Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Up-regulation of Hsp27 *. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 285(46): 35528-35536, http://dx.doi.org/10.1074/jbc.M110.152686.

   

（1） 微囊藻毒素在微囊藻群体形成中的作用及机制研究，主持，国家级，2011-01--2013-12
（2） 藻毒素快速生物检测技术，主持，国家级，2009-10--2012-01
（3） 蓝藻毒素在群体形成中的作用，主持，国家级，2009-07--2012-07
（4） 微囊藻胶被形成及群体竞争优势的生理学基础，主持，国家级，2008-09--2013-08

已指导学生

孙晓云  硕士研究生  071004-水生生物学  

现指导学生

魏念  硕士研究生  071004-水生生物学