基本信息
林旭  女  博导  中国科学院上海营养与健康研究所
电子邮件: xlin@sibs.ac.cn
通信地址: 上海市岳阳路320号
邮政编码: 200031
部门/实验室:营养科学研究所

招生信息

   
招生专业
100104-病理学与病理生理学
招生方向
代谢性疾病相关的遗传和营养等环境因素的人群队列和干预研究

教育背景

1990-09--美国康奈尔大学营养科学分部   营养生物化学专业获博
1978-10--浙江中医药大学   学士学位

工作经历

   
工作简历
2003-08~现在, 中国科学院上海生命科学研究院营养科学研究所, 研究员、博导
2003-01~现在, 美国国家环境保护署,国家健康与环境影响研究实验室, 研究员
2001-08~现在, 美国杜克大学医学中心外科系泌尿科, 研究员
1999-04~现在, 美国国立卫生研究院,美国国家老龄研究院,美国杜克大学医学中心老龄研究中心外科系, 博士后研究员
1997-10~现在, 美国国立卫生研究院、美国国家环境卫生科学研究院,美国北卡罗来那大学医学院病理和实验医学系, 博士后研究员
1990-09~现在, 美国康奈尔大学营养科学分部, 营养生物化学专业获博
1983-07~现在, 浙江省中医药大学附属浙江省中医院, 住院医师
1978-10~现在, 浙江中医药大学, 学士学位
社会兼职
2016-01-01-今,《Nutrition and Metabolism》杂志, 共同主编
2013-01-01-今,中国营养学会基础营养研究分会, 主任
2003-07-28-今,中国营养学会理事, 常务理事
2003-07-28-今,上海营养学会理事, 常务理事

专利与奖励

   
奖励信息
(1) 中国营养学会杰出贡献奖, , 其他, 2015
(2) 中国科学院科普工作先进个人, , 院级, 2014
(3) 中国十大最具影响力糖尿病研究奖, , 市地级, 2012
(4) 国务院政府特殊津贴, , 国家级, 2011
(5) 中科院建院60周年成果展, , 院级, 2009
(6) 中国科学院2008年度主要科技进展, , 院级, 2009
(7) 上海生命科学研究院首席科学家, , 院级, 2008
(8) 上海市领军人才, , 市地级, 2008
(9) 上海市三八红旗手, , 市地级, 2008
(10) 比翼双飞模范佳侣, , 市地级, 2008
专利成果
( 1 ) 亚麻子及其衍生物的新用途, 2010, 第 1 作者, 专利号: 201010538933.8
( 2 ) 膳食分析系统(版本号:V1.00), 2008, 第 1 作者, 专利号: 2008120420
( 3 ) 2型糖尿病易感位点及检测方法和试剂盒, 2012, 第 1 作者, 专利号: 201210226735.7
( 4 ) 中国人群体脂百分比预测公式的建立与验证, 2014, 第 1 作者, 专利号: 201410403782.3

出版信息

   
发表论文
(1) Nickel Exposure is Associated with the Prevalence of Type 2 Diabetes in Chinese Adults. , Int J Epidemiol. , 2015, 第 11 作者
(2) Dairy consumption, type 2 diabetes, and changes in cardiometabolic traits: a prospective cohort study of middle-aged and older chinese in beijing and shanghai., Diabetes Care. , 2014, 第 11 作者
(3) Lipopolysaccharide binding protein, obesity status, and incidence of metabolic syndrome: a prospective study among middle-aged and older Chinese. , Diabetologia., 2014, 第 11 作者
(4) Association of genetic predisposition to obesity with type 2 diabetes risk in Chinese Hans. , Diabetologia. , 2014, 第 11 作者
(5)  A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans., Diabetes. , 2013, 第 11 作者
(6) Thiamine nutritional status and depressive symptoms are inversely associated among older Chinese adults. , Journal of Nutrition. , 2013, 第 11 作者
(7) Associations of fatty acids in the de novo lipogenesis pathway with risk of metabolic syndrome in middle-aged and older Chinese., Am J Clin Nutr., 2013, 第 11 作者
(8) Erythrocyte trans-fatty acids, type 2 diabetes, and cardiovascular risk factors in middle-aged and older Chinese. , Diabetologia., 2012, 第 11 作者
(9) Associations of erythrocyte palmitoleic acid with adipokines, inflammatory markers, and metabolic syndrome in middle-aged and older Chinese., Am J Clin Nutr., 2012, 第 11 作者
(10) Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans. , J Hypertens., 2011, 第 11 作者
(11) Effects of Body Fat on the Associations of High-molecular-weight Adiponectin, Leptin and Soluble Leptin Receptor with Metabolic Syndrome in Chinese., PLoS One., 2011, 第 11 作者
(12)  Lean body mass, interleukin 18, and metabolic syndrome in apparently healthy chinese., PLoS One. , 2011, 第 11 作者
(13) Substituting Brown Rice for White Rice to Lower Diabetes Risk: A Focus Group Study in Chinese Adults. , J Am Diet Assoc., 2010, 第 11 作者
(14) MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai. , BMC Med Genet., 2010, 第 11 作者
(15) Independent and Opposite Associations of Trunk and Leg Fat Depots with Adipokines, Inflammatory Markers, and Metabolic Syndrome in Middle-Aged and Older Chinese Men and Women., Journal of Clinical Endocrinology and Metabolism., 2010, 第 11 作者
(16) A Marker of Endotoxemia Is Associated With Obesity and Related Metabolic Disorders in Apparently Healthy Chinese., Diabetes Care, 2010, 第 11 作者
(17) Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population. , Diabetologia., 2010, 第 11 作者
(18) Lifestyle counseling and supplementation with flaxseed or walnuts influence the management of metabolic syndrome., J Nutr., 2010, 第 11 作者
(19)  Opposite associations of trunk and leg fat depots with plasma ferritin levels in middle-aged and older Chinese men and women. , PLoS One., 2010, 第 11 作者
(20) Associations of alcohol consumption with diabetes mellitus and impaired fasting glycemia among middle-aged and elderly Chinese., BMC public health. , 2010, 第 11 作者
(21) Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population. , PLoS One., 2010, 第 11 作者
(22) Identification of new genetic risk variants for type 2 diabetes., PLoS Genet., 2010, 第 11 作者
(23) Mapping the availability and accessibility of healthy food in rural and urban New Zealand - Te Wai o Rona: Diabetes Prevention Strategy., Public Health Nutrition. , 2010, 第 11 作者
(24) Plasma 25-hydroxyvitamin D Concentration and Metabolic Syndrome among Middle-aged and Elderly Chinese., Diabetes Care. , 2009, 第 11 作者
(25) Meta-analysis of the effects of flaxseed interventions on the blood lipids., American Journal of Clinical Nutrition., 2009, 第 11 作者
(26) Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese. , Journal of Affective Disorders., 2009, 第 11 作者
(27) Associations of physical activity with inflammatory factors, adipocytokines and metabolic syndrome in middle-aged and older Chinese people. , Circulation., 2009, 第 11 作者
(28) Franco OH. Sleep Quality in Middle-aged and Elderly Chinese: distribution, associated factors and associations with cardio-metabolic risk factors. , BMC Public Health., 2009, 第 11 作者
(29) Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. , Human Molecular Genetics. , 2009, 第 11 作者
(30) Franco OH. Self-Rated Health in middle-aged and elderly Chinese: distribution, determinants and associations with cardio-metabolic risk factors., BMC Public Health., 2009, 第 11 作者
(31) Associations of inflammatory factors with glycemic status among middle-aged and older Chinese people., Clin Endocrinol., 2009, 第 11 作者
(32) Independent association of body-size adjusted fat mass and fat-free mass with the metabolic syndrome in Chinese., Annals of Human Biology. , 2009, 第 11 作者
(33) Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients., British Journal of Nutrition. , 2009, 第 11 作者
(34) Role of Iron Deficiency and Overload in the Pathogenesis of Diabetes and Diabetic Complications., Current Medicinal Chemistry., 2009, 第 11 作者
(35) Association of GCKRrs 780094 alone or in combination with GCKrs 1799884 with type 2 diabetes and related traits in a Chinese Han population., Diabetologia., 2009, 第 11 作者
(36) Obesity related metabolic abnormalities: Distribution and geographic differences among middle-aged and older Chinese populations., Preventive Medicine., 2009, 第 2 作者
(37) Enterolactone inhibits insulin-like growth factor-1 receptor signaling in human prostatic carcinoma PC-3 cells., Journal of Nutrition., 2009, 第 11 作者
(38) RBP4 variants are significantly associated with plasmaRBP4 levels and hypertriglyceridemia risk in Chinese Hans., Journal of Lipid Research. , 2009, 第 11 作者
(39) Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8 and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population, Diabetes, 2008, 第 11 作者
(40) Variants in FTO gene are not associated with obesity in a Chinese Han population, Diabetes., 2008, 第 11 作者
(41) Adiponectin and Metabolic Syndrome in Middle-aged and Elderly Chinese, Obesity, 2008, 第 11 作者
(42) Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study., Journal of Affective Disorders., 2008, 第 11 作者
(43) Prevalence and geographic disparity of depressive symptoms among middle-aged and elderly in China, Journal of Affective Disorders, 2008, 第 11 作者
(44) The Association of Depressive Symptoms with Inflammatory Factors and Adipokines in Middle-aged and Older Chinese., PLoS ONE, 2008, 第 11 作者
(45) Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation. , European Journal of Human Genetics., 2008, 第 11 作者
(46) Soy protein intake has sex-specific effects on the risk of metabolic syndrome in middle-aged and elderly Chinese., Journal of Nutrition., 2008, 第 11 作者
(47) Ferritin concentrations, metabolic syndrome, and type 2 diabetes in middle-aged and elderly Chinese. , Journal of Clinical Endocrinology and Metabolism, 2008, 第 11 作者
(48) Associations of resistin with inflammatory and fibrinolytic markers, insulin resistance, and metabolic syndrome in middle-aged and older Chinese., European Journal of Endocrinology., 2008, 第 11 作者
(49) Macrosomia is associated with high weight-for-height in children aged 1-3 years in Shanghai, China., International Journal of Obesity., 2008, 第 11 作者
(50) Dietary energy density predicts the risk of incident type 2 diabetes: the European Prospective Investigation of Cancer (EPIC)-Norfolk Study, Diabetes Care, 2008, 第 11 作者

科研活动

   
科研项目
( 1 ) 2型糖尿病全基因组关联分析和药物基因组学研究, 主持, 国家级, 2009-01--2011-12
( 2 ) 基因与环境因素相互作用对2型糖尿病发病的影响研究, 主持, 国家级, 2010-01--2013-12
( 3 ) 重大慢性疾病发生发展的营养与遗传机制的研究, 主持, 部委级, 2008-10--2011-09
( 4 ) 营养因素与2型糖尿病的关系及作用机制, 参与, 国家级, 2011-01--2013-12
( 5 ) 中国人群的营养遗传与慢性代谢性疾病的关系及预防研究, 参与, 部委级, 2011-01--2013-12
( 6 ) 糖脂代谢调控在代谢性疾病发生中的致病机制研究, 参与, 国家级, 2011-01--2013-12
( 7 ) 脂代谢紊乱疾病发生发展进程中的标志性代谢产物研究, 参与, 国家级, 2010-12--2015-12
( 8 ) GRK5 基因区域与2 型糖尿病相关的功能性位点的研究, 主持, 国家级, 2015-01--2018-12
( 9 ) 中国万人脂肪酸谱的建立、特征及其与疾病的关系, 主持, 部委级, 2016-01--2018-12
( 10 ) 新时期国民营养和粮食需求战略研究计划 2017/1/1 2017/12/31 700, 主持, 部委级, 2017-01--2017-12
( 11 ) 肥胖及2型糖尿病个体化治疗靶标发现与新技术研发, 主持, 国家级, 2017-01--2019-12
参与会议
(1)Linking of omics-based biomarkers with cardiometabolic diseases in Chinese   2016-05-27
(2)The findings from 2 stages of vitamin D trials in Chinese   2016-01-28
(3)Genetic Variants, Nutrient-related Biomarkers Metabolic Diseases in Chinese   2015-10-14
(4)Genetic variants, nutrient-related biomarkers on metabolic diseases in Chinese   2015年联合利华合作研讨会   2015-09-21
(5)Linking of Omics-based Biomarkers with Nutritional Status and Cardiometabolic Outcome in Chinese   2015营养基因组学研究与应用研讨会   2015-05-15
(6)Nutrition and Diabetes- roles of nutrient and other biomarkers in disease prediction   林旭   2014-11-20
(7)The productive role of omics-based biomarkers in the development of type 2 diabetes   林旭   2014-11-07
(8)营养素生物标记,基因变异,以及其交互作用与营养状况和代谢性疾病的中国人群研究(Studies of Nutrient Biomarkers, Genetic Variants and Their Interactions on Nutritional Status and Metabolic Disease in Chinese Population)   第三届“广州营养与健康国际学术研讨会”   林旭   2014-09-16
(9)Effects of nutrition, lifestyle and genetic factors on metabolic abnormalities among Chinese   林旭   2013-09-14
(10)Effects of genetic variants and nutritional factors on metabolic disease among Chinese populations   第12届国际人类遗传学大会和第61届美国人类遗传学会年会   林旭   2011-11-01
(11)中国人群红细胞膜脂肪酸与慢性代谢性疾病的关系研   中国居民蛋白质脂肪摄入状况与相关慢性病学术研讨会   林旭   2011-07-02