基本信息
林旭  女  博导  中国科学院上海营养与健康研究所
电子邮件: xlin@sibs.ac.cn
通信地址: 上海市岳阳路320号
邮政编码: 200031
部门/实验室:营养科学研究所

招生信息

   
招生专业
100104-病理学与病理生理学
招生方向
代谢性疾病相关的遗传和营养等环境因素的人群队列和干预研究

教育背景

1990-09--美国康奈尔大学营养科学分部   营养生物化学专业获博
1978-10--浙江中医药大学   学士学位

工作经历

   
工作简历
2003-08~现在, 中国科学院上海生命科学研究院营养科学研究所, 研究员、博导
2003-01~现在, 美国国家环境保护署,国家健康与环境影响研究实验室, 研究员
2001-08~现在, 美国杜克大学医学中心外科系泌尿科, 研究员
1999-04~现在, 美国国立卫生研究院,美国国家老龄研究院,美国杜克大学医学中心老龄研究中心外科系, 博士后研究员
1997-10~现在, 美国国立卫生研究院、美国国家环境卫生科学研究院,美国北卡罗来那大学医学院病理和实验医学系, 博士后研究员
1990-09~现在, 美国康奈尔大学营养科学分部, 营养生物化学专业获博
1983-07~现在, 浙江省中医药大学附属浙江省中医院, 住院医师
1978-10~现在, 浙江中医药大学, 学士学位
社会兼职
2016-01-01-今,《Nutrition and Metabolism》杂志, 共同主编
2013-01-01-今,中国营养学会基础营养研究分会, 主任
2003-07-28-今,中国营养学会理事, 常务理事
2003-07-28-今,上海营养学会理事, 常务理事

专利与奖励

   
奖励信息
(1) 中国营养学会杰出贡献奖, , 其他, 2015
(2) 中国科学院科普工作先进个人, , 院级, 2014
(3) 中国十大最具影响力糖尿病研究奖, , 市地级, 2012
(4) 国务院政府特殊津贴, , 国家级, 2011
(5) 中科院建院60周年成果展, , 院级, 2009
(6) 中国科学院2008年度主要科技进展, , 院级, 2009
(7) 上海生命科学研究院首席科学家, , 院级, 2008
(8) 上海市领军人才, , 市地级, 2008
(9) 上海市三八红旗手, , 市地级, 2008
(10) 比翼双飞模范佳侣, , 市地级, 2008
专利成果
( 1 ) 亚麻子及其衍生物的新用途, 2010, 第 1 作者, 专利号: 201010538933.8
( 2 ) 膳食分析系统(版本号:V1.00), 2008, 第 1 作者, 专利号: 2008120420
( 3 ) 2型糖尿病易感位点及检测方法和试剂盒, 2012, 第 1 作者, 专利号: 201210226735.7
( 4 ) 中国人群体脂百分比预测公式的建立与验证, 2014, 第 1 作者, 专利号: 201410403782.3

出版信息

   
发表论文
(1) Nickel Exposure is Associated with the Prevalence of Type 2 Diabetes in Chinese Adults. , Int J Epidemiol. , 2015, 通讯作者
(2) Dairy consumption, type 2 diabetes, and changes in cardiometabolic traits: a prospective cohort study of middle-aged and older chinese in beijing and shanghai., Diabetes Care. , 2014, 通讯作者
(3) Lipopolysaccharide binding protein, obesity status, and incidence of metabolic syndrome: a prospective study among middle-aged and older Chinese. , Diabetologia., 2014, 通讯作者
(4) Association of genetic predisposition to obesity with type 2 diabetes risk in Chinese Hans. , Diabetologia. , 2014, 通讯作者
(5)  A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans., Diabetes. , 2013, 通讯作者
(6) Thiamine nutritional status and depressive symptoms are inversely associated among older Chinese adults. , Journal of Nutrition. , 2013, 通讯作者
(7) Associations of fatty acids in the de novo lipogenesis pathway with risk of metabolic syndrome in middle-aged and older Chinese., Am J Clin Nutr., 2013, 通讯作者
(8) Erythrocyte trans-fatty acids, type 2 diabetes, and cardiovascular risk factors in middle-aged and older Chinese. , Diabetologia., 2012, 通讯作者
(9) Associations of erythrocyte palmitoleic acid with adipokines, inflammatory markers, and metabolic syndrome in middle-aged and older Chinese., Am J Clin Nutr., 2012, 通讯作者
(10) Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans. , J Hypertens., 2011, 通讯作者
(11) Effects of Body Fat on the Associations of High-molecular-weight Adiponectin, Leptin and Soluble Leptin Receptor with Metabolic Syndrome in Chinese., PLoS One., 2011, 通讯作者
(12)  Lean body mass, interleukin 18, and metabolic syndrome in apparently healthy chinese., PLoS One. , 2011, 通讯作者
(13) Substituting Brown Rice for White Rice to Lower Diabetes Risk: A Focus Group Study in Chinese Adults. , J Am Diet Assoc., 2010, 通讯作者
(14) MTNR1B rs10830963 is associated with fasting plasma glucose, HbA1C and impaired beta-cell function in Chinese Hans from Shanghai. , BMC Med Genet., 2010, 通讯作者
(15) Independent and Opposite Associations of Trunk and Leg Fat Depots with Adipokines, Inflammatory Markers, and Metabolic Syndrome in Middle-Aged and Older Chinese Men and Women., Journal of Clinical Endocrinology and Metabolism., 2010, 通讯作者
(16) A Marker of Endotoxemia Is Associated With Obesity and Related Metabolic Disorders in Apparently Healthy Chinese., Diabetes Care, 2010, 通讯作者
(17) Combined effects of 17 common genetic variants on type 2 diabetes risk in a Han Chinese population. , Diabetologia., 2010, 通讯作者
(18) Lifestyle counseling and supplementation with flaxseed or walnuts influence the management of metabolic syndrome., J Nutr., 2010, 通讯作者
(19)  Opposite associations of trunk and leg fat depots with plasma ferritin levels in middle-aged and older Chinese men and women. , PLoS One., 2010, 通讯作者
(20) Associations of alcohol consumption with diabetes mellitus and impaired fasting glycemia among middle-aged and elderly Chinese., BMC public health. , 2010, 通讯作者
(21) Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population. , PLoS One., 2010, 通讯作者
(22) Identification of new genetic risk variants for type 2 diabetes., PLoS Genet., 2010, 通讯作者
(23) Mapping the availability and accessibility of healthy food in rural and urban New Zealand - Te Wai o Rona: Diabetes Prevention Strategy., Public Health Nutrition. , 2010, 通讯作者
(24) Plasma 25-hydroxyvitamin D Concentration and Metabolic Syndrome among Middle-aged and Elderly Chinese., Diabetes Care. , 2009, 通讯作者
(25) Meta-analysis of the effects of flaxseed interventions on the blood lipids., American Journal of Clinical Nutrition., 2009, 通讯作者
(26) Association between depressive symptoms and 25-hydroxyvitamin D in middle-aged and elderly Chinese. , Journal of Affective Disorders., 2009, 通讯作者
(27) Associations of physical activity with inflammatory factors, adipocytokines and metabolic syndrome in middle-aged and older Chinese people. , Circulation., 2009, 通讯作者
(28) Franco OH. Sleep Quality in Middle-aged and Elderly Chinese: distribution, associated factors and associations with cardio-metabolic risk factors. , BMC Public Health., 2009, 通讯作者
(29) Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. , Human Molecular Genetics. , 2009, 通讯作者
(30) Franco OH. Self-Rated Health in middle-aged and elderly Chinese: distribution, determinants and associations with cardio-metabolic risk factors., BMC Public Health., 2009, 通讯作者
(31) Associations of inflammatory factors with glycemic status among middle-aged and older Chinese people., Clin Endocrinol., 2009, 通讯作者
(32) Independent association of body-size adjusted fat mass and fat-free mass with the metabolic syndrome in Chinese., Annals of Human Biology. , 2009, 通讯作者
(33) Effects of a flaxseed-derived lignan supplement on C-reactive protein, IL-6 and retinol-binding protein 4 in type 2 diabetic patients., British Journal of Nutrition. , 2009, 通讯作者
(34) Role of Iron Deficiency and Overload in the Pathogenesis of Diabetes and Diabetic Complications., Current Medicinal Chemistry., 2009, 通讯作者
(35) Association of GCKRrs 780094 alone or in combination with GCKrs 1799884 with type 2 diabetes and related traits in a Chinese Han population., Diabetologia., 2009, 通讯作者
(36) Obesity related metabolic abnormalities: Distribution and geographic differences among middle-aged and older Chinese populations., Preventive Medicine., 2009, 第 2 作者
(37) Enterolactone inhibits insulin-like growth factor-1 receptor signaling in human prostatic carcinoma PC-3 cells., Journal of Nutrition., 2009, 通讯作者
(38) RBP4 variants are significantly associated with plasmaRBP4 levels and hypertriglyceridemia risk in Chinese Hans., Journal of Lipid Research. , 2009, 通讯作者
(39) Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8 and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population, Diabetes, 2008, 通讯作者
(40) Variants in FTO gene are not associated with obesity in a Chinese Han population, Diabetes., 2008, 通讯作者
(41) Adiponectin and Metabolic Syndrome in Middle-aged and Elderly Chinese, Obesity, 2008, 通讯作者
(42) Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China Study., Journal of Affective Disorders., 2008, 通讯作者
(43) Prevalence and geographic disparity of depressive symptoms among middle-aged and elderly in China, Journal of Affective Disorders, 2008, 通讯作者
(44) The Association of Depressive Symptoms with Inflammatory Factors and Adipokines in Middle-aged and Older Chinese., PLoS ONE, 2008, 通讯作者
(45) Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation. , European Journal of Human Genetics., 2008, 通讯作者
(46) Soy protein intake has sex-specific effects on the risk of metabolic syndrome in middle-aged and elderly Chinese., Journal of Nutrition., 2008, 通讯作者
(47) Ferritin concentrations, metabolic syndrome, and type 2 diabetes in middle-aged and elderly Chinese. , Journal of Clinical Endocrinology and Metabolism, 2008, 通讯作者
(48) Associations of resistin with inflammatory and fibrinolytic markers, insulin resistance, and metabolic syndrome in middle-aged and older Chinese., European Journal of Endocrinology., 2008, 通讯作者
(49) Macrosomia is associated with high weight-for-height in children aged 1-3 years in Shanghai, China., International Journal of Obesity., 2008, 通讯作者
(50) Dietary energy density predicts the risk of incident type 2 diabetes: the European Prospective Investigation of Cancer (EPIC)-Norfolk Study, Diabetes Care, 2008, 通讯作者

科研活动

   
科研项目
( 1 ) 2型糖尿病全基因组关联分析和药物基因组学研究, 主持, 国家级, 2009-01--2011-12
( 2 ) 基因与环境因素相互作用对2型糖尿病发病的影响研究, 主持, 国家级, 2010-01--2013-12
( 3 ) 重大慢性疾病发生发展的营养与遗传机制的研究, 主持, 部委级, 2008-10--2011-09
( 4 ) 营养因素与2型糖尿病的关系及作用机制, 参与, 国家级, 2011-01--2013-12
( 5 ) 中国人群的营养遗传与慢性代谢性疾病的关系及预防研究, 参与, 部委级, 2011-01--2013-12
( 6 ) 糖脂代谢调控在代谢性疾病发生中的致病机制研究, 参与, 国家级, 2011-01--2013-12
( 7 ) 脂代谢紊乱疾病发生发展进程中的标志性代谢产物研究, 参与, 国家级, 2010-12--2015-12
( 8 ) GRK5 基因区域与2 型糖尿病相关的功能性位点的研究, 主持, 国家级, 2015-01--2018-12
( 9 ) 中国万人脂肪酸谱的建立、特征及其与疾病的关系, 主持, 部委级, 2016-01--2018-12
( 10 ) 新时期国民营养和粮食需求战略研究计划 2017/1/1 2017/12/31 700, 主持, 部委级, 2017-01--2017-12
( 11 ) 肥胖及2型糖尿病个体化治疗靶标发现与新技术研发, 主持, 国家级, 2017-01--2019-12
参与会议
(1)Linking of omics-based biomarkers with cardiometabolic diseases in Chinese   2016-05-27
(2)The findings from 2 stages of vitamin D trials in Chinese   2016-01-28
(3)Genetic Variants, Nutrient-related Biomarkers Metabolic Diseases in Chinese   2015-10-14
(4)Genetic variants, nutrient-related biomarkers on metabolic diseases in Chinese   2015年联合利华合作研讨会   2015-09-21
(5)Linking of Omics-based Biomarkers with Nutritional Status and Cardiometabolic Outcome in Chinese   2015营养基因组学研究与应用研讨会   2015-05-15
(6)Nutrition and Diabetes- roles of nutrient and other biomarkers in disease prediction   林旭   2014-11-20
(7)The productive role of omics-based biomarkers in the development of type 2 diabetes   林旭   2014-11-07
(8)营养素生物标记,基因变异,以及其交互作用与营养状况和代谢性疾病的中国人群研究(Studies of Nutrient Biomarkers, Genetic Variants and Their Interactions on Nutritional Status and Metabolic Disease in Chinese Population)   第三届“广州营养与健康国际学术研讨会”   林旭   2014-09-16
(9)Effects of nutrition, lifestyle and genetic factors on metabolic abnormalities among Chinese   林旭   2013-09-14
(10)Effects of genetic variants and nutritional factors on metabolic disease among Chinese populations   第12届国际人类遗传学大会和第61届美国人类遗传学会年会   林旭   2011-11-01
(11)中国人群红细胞膜脂肪酸与慢性代谢性疾病的关系研   中国居民蛋白质脂肪摄入状况与相关慢性病学术研讨会   林旭   2011-07-02