基本信息
肖吉昌  男  博导  中国科学院上海有机化学研究所
电子邮件: jchxiao@mail.sioc.ac.cn
通信地址: 上海市零陵路345号
邮政编码: 200032

研究领域

   

招生信息

   
招生专业
070303-有机化学
招生方向
氟化学
稀土萃取与稀土化学
氟盐化学

教育背景

2000-08--中科院上海有机所   博士
学历
-- 研究生
学位
-- 博士

工作经历

   
工作简历
2005-08~现在, 中科院上海有机所, 研究员
社会兼职
   

教授课程

有机氟化学

专利与奖励

   
奖励信息
   
专利成果
( 1 ) 一种具有推拉电子结构的咪唑离子盐、制备方法及其用途, 发明, 2010, 第 1 作者, 专利号: CN 101143848
( 2 ) 一种高密度离子液体及其制备方法, 发明, 2011, 第 1 作者, 专利号: ZL200910053429.6
( 3 ) 一类含氟苯并噻唑磺酰类化合物、制备及应用, 发明, 2011, 第 1 作者, 专利号: ZL200710173706.8
( 4 ) 三氟甲基芳基锍盐在金属引发下对杂环化合物的三氟甲基化, 发明, 2013, 第 1 作者, 专利号: ZL201010272754.4
( 5 ) 一种用于制备熔盐的熔炼炉, 实用新型, 2014, 第 1 作者, 专利号: ZL201320216709.6
( 6 ) 一种用于制备氟化物熔盐的反应罐, 实用新型, 2015, 第 1 作者, 专利号: ZL201520614732.X
( 7 ) 一种气体分布器及包括其的鼓泡反应器, 实用新型, 2016, 第 1 作者, 专利号: ZL201520747785.9
( 8 ) 一种高纯度的氟化物熔盐及其制备方法, 发明, 2016, 第 1 作者, 专利号: ZL201310148929.4
( 9 ) 一种萃取体系、萃取方法及反萃取方法, 发明, 2016, 第 1 作者, 专利号: ZL201410010398.7

出版信息

   
发表论文
(1) One-Step Synthesis of High-purity Li2BeF4 Molten Salt, J. Fluorine Chem. 2016, 181, 30-35, 2016, 通讯作者
(2) O-difluoromethylation of 1,3-diones with S-difluoromethyl sulfonium salt, RSC Adv. 2016, 6, 35705-35708, 2016, 通讯作者
(3) Nucleophilic arylation with tetraarylphosphonium salts, Nat. Commun. 2016, 7: 10337 doi: 10.1038/ncomms10337, 2016, 通讯作者
(4) Cu-catalyzed C-H trifluoromethylation of 3-arylprop-1-ynes for the selective construction of allenic Csp2-CF3 and propargyl Csp3-CF3 bonds, Org. Lett. 2016, 18, 1000-1003, 2016, 通讯作者
(5) DBU-Promoted Trifluoromethylation of Aryl Iodides with Difluoromethyltriphenylphosphonium Bromide, Chin. J. Chem. 2016, 34, 481-484, 2016, 通讯作者
(6) Prediction of solubility properties from transfer energies for acidic phosphorus-containing Rare-Earth extractants using Implicit Solvation Model, Solvent Extr. Ion Exch. 2016, 34, 347-354, 2016, 通讯作者
(7) pKa Prediction for Acidic Phosphorus-Containing Compounds Using Multiple Linear Regression with Computational Descriptors, J. Comput. Chem. 2016, 37, 1668-1671, 2016, 通讯作者
(8) A Trifluoromethylcarbene Source, Org. Lett. 2016, 18, 2471-2474, 2016, 通讯作者
(9) α,β-Substituent effect of dialkylphosphinic acids on lanthanide extraction, RSC Adv. 2016, 6, 56004-56008, 2016, 通讯作者
(10) Hydroperfluoroalkylation of electron-deficient olefins with perfluoroalkyl iodides promoted by Zinc / viologen, RSC Adv. 2016, 6, 60080-60083, 2016, 通讯作者
(11) Direct Nucleophilic Difluoromethylation of Carbonyl Compounds, Org. Lett. 2016, 18, 3206-3209, 2016, 通讯作者
(12) FLiNaK熔盐中微量氧的测定, Determination of trace oxygen in FLiNaK molten salt, 中国无机分析化学,2015, 5(1), 45-48, 2015, 通讯作者
(13) 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)-Promoted Decomposition of Difluorocarbene and the Subsequent Trifluoromethylation, Org. Lett. 2015, 17, 532-535, 2015, 通讯作者
(14) Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylation, Chem. Commun. 2015, 51, 8805-8808, 2015, 通讯作者
(15) An overview of reductive trifluoromethylation reactions using electrophilic '+CF3' reagents, Tetrahedron 2015, 71, 7949-7976, 2015, 通讯作者
(16) Diastereoselective Johnson-Corey-Chaykovsky trifluoroethylidenation, Chem. Commun. 2015, 51, 13127-13130, 2015, 通讯作者
(17) Recent Advances in C-H Trifluoromethylthiolation and Trifluoromethoxylation Reactions, Curr. Org. Chem. 2015, 19, 1541-1553, 2015, 通讯作者
(18) One-pot synthesis of gem-difluorostyrenes from benzyl bromide via olefination of phosphonium ylide with difluorocarbene, J. Fluorine Chem. 2015, 179, 116-120, 2015, 通讯作者
(19) Difluorocarbene-Derived Trifluoromethylthiolation and [18F]Trifluoromethylthiolation of Aliphatic Electrophiles, Angew. Chem. Int. Ed. 2015, 54, 13236-13240, 2015, 通讯作者
(20) Cross-Coupling between difluorocarbene and carbene-derived in-termediates generated from diazocompounds for the synthesis of gem-difluoroolefins, Org. Lett. 2015, 17, 6150-6153, 2015, 通讯作者
(21) Microwave-assisted synthesis of dialkylphosphinic acids and a structure–reactivity study in Rare Earth metal extraction, RSC Adv. 2015, 5, 104258-104262, 2015, 通讯作者
(22) Difluoromethylation and Trifluoromethylation Reagents Derived from Tetrafluoroethane β-Sultone: Synthesis, Reactivity and Applications, Coord. Chem. Rev. 2014, 261, 28-72, 2014, 通讯作者
(23) Rh-Catalyzed Allylic C-F Bond Activation: The Stereosynthesis of Trisubstituted Monofluoroalkenes and A Mechanism Study, Org. Biomol. Chem. 2014, 12, 581-588, 2014, 通讯作者
(24) Boron-trihalide-promoted Regioselective Ring-opening Reactions of gem-Difluorocyclopropyl Ketones, Chem. Commun. 2014, 50, 1077-1079, 2014, 通讯作者
(25) Decarboxylative Julia–Kocienski gem-difluoroolefination of 2-Pyridinyl sulfonyl-difluoroacetate, Eur. J. Org. Chem. 2014, 928-932, 2014, 通讯作者
(26) Copper-mediated Trifluoromethylation of Propargyl Acetates Leading to Trifluoromethyl-allenes, Org. Biomol. Chem. 2014, 12, 2903–2906, 2014, 通讯作者
(27) FLiNaK熔盐的制备, Preparation of FLiNaK molten salt, 核技术,2014, 37, 050604-1-5, 2014, 通讯作者
(28) Wittig gem-Difluoroolefination of Aldehydes with Difluoromethyltriphenylphosphonium Bromide, J. Fluorine Chem. 2014, 163, 38-41, 2014, 通讯作者
(29) 盐析剂存在下稀土含量的准确测定, Accurate Measurement of Rare Earth in the Presence of Salting-Out Agent—NaCl, 中国稀土学报 2014, 32, 370-376, 2014, 通讯作者
(30) Cu-promoted Oxidative Trifluoromethylation of Terminal Alkynes with Difluoromethylene Phosphobetaine, Chin. J. Chem. 2014, 32, 689-693, 2014, 通讯作者
(31) Recent advances in asymmetric fluorination and fluoroalkylation reactions via organocatalysis, Tetrahedron Lett. 2014, 55, 6147-6155, 2014, 通讯作者
(32) Copper-catalyzed Tandem Trifluoromethylation/ Cyclization of Internal Alkynes, Org. Chem. Front. 2014, 1, 1280-1284, 2014, 通讯作者
(33) Stereoselective Synthesis of α-Trifluoromethyl Enones by Au(I)/Cu(I)-Cocatalyzed Tandem 1,3-Acyloxy Migration/Trifluoromethylation of Propargyl Acetates, Eur. J. Org. Chem. 2014, 7948-7954, 2014, 通讯作者
(34) Direct N-gem-difluorocyclopropylation of nitro-heterocycles by utilizing gem-difluorocyclopropyl Tosylate, Chin. Chem. Lett. 2014, 25, 24-28, 2014, 通讯作者
(35) Copper-mediated trifluoromethylation of terminal alkynes by S-(trifluoromethyl)diarylsulfonium salt, Chin. J. Chem. 2013, 31, 915-920, 2013, 通讯作者
(36) Synthesis and decarboxylative Wittig reaction of difluoromethylene phosphobetaine, Chem. Commun. 2013, 49, 7513-7515, 2013, 通讯作者
(37) A novel reaction of gem-difluorocyclopropyl ketones with nitriles leading to 2-fluoropyrroles, Chem. Commun. 2013, 49, 9833-9835, 2013, 通讯作者
(38) Conversion between Difluorocarbene and Difluoromethylene Ylide, Chem. Eur. J. 2013, 19, 15261-15266, 2013, 通讯作者
(39) 氯乙酸缓冲体系在稀土测定中的应用研究, Research on buffer solution of chloroacetic acid in rare earth detection, 中国稀土学报 2013, 31, 636-640, 2013, 通讯作者
(40) Copper-catalyzed Trifluoromethylation of Alkenes with Electrophilic Trifluoromethylating Reagent, Beilstein J. Org. Chem. 2013, 9, 2635-2640, 2013, 通讯作者
(41) Bi-Functional Fluoroalkylation Reagents: An introduction to Halo-substituted 3-Oxa-Perfluoroalkanesulfonyl Fluorides, Tetrahedron 2013, 69, 10955-10989, 2013, 通讯作者
(42) Efficient Synthesis of 1-Alkyl-3-methylimidazolium Fluorides and Possibility of the Existence of Hydrogen Bonding Between Fluoride Anion and C(sp3)–H, J. Fluorine Chem. 2012, 133, 160-162., 2012, 通讯作者
(43) Electrophilic Fluoroalkylation of Ni(II) N-Confused Porphyrins with Fluoroalkylarylsulfonium Salts, J. Org. Chem. 2012, 77, 3604-3608., 2012, 通讯作者
(44) Progress in fluoroalkylation of organic compounds via sulfinatodehalogenation initiation system, Chem. Soc. Rev. 2012, 41, 4536-4559., 2012, 通讯作者
(45) The asymmetric synthesis of CF3- or -CF2-substituted tetrahydroquinolines by employing a chiral phosphoric acid as catalyst, Chem. Commun. 2012, 48, 7738-7740., 2012, 通讯作者
(46) 聚苯乙烯-co-聚(2,3,4,5,6-五氟苯乙烯)共聚物:合成及其多孔薄膜的制备, Polystyrene-co-poly(2,3,4,5,6-pentafluorostyrene) Copolymers: Synthesis and Fabrication of Their Porous Films, 化学学报,2012, 70, 1125-1130, 2012, 通讯作者
(47) Generation of the CF3 radical from trifluoromethylsulfonium triflate and, Chem. Commun., 2011, 47, 6632–6634, 2011, 通讯作者
(48) Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds by Trifluoromethyl Sulfonium Salts, Angew. Chem. Int. Ed. 2011, 50, 1896-1900, 2011, 通讯作者
(49) Monofluorovinyl Tosylate: A Useful Building Block for the Synthesis of Terminal Vinyl Monofluorides via Suzuki-Miyaura Coupling, Org. Lett., 2011, 13, 560–563, 2011, 通讯作者
(50) Thermal rearrangement of substituted difluoro(methylene)cyclopropane, J. Fluorine Chem. 2011, 132, 63-67, 2011, 通讯作者
(51) N-Heterocyclic Carbene Catalyzed Reaction of Alkynyl Aldehydes with 1,3-Ketoesters or 1,3-Diketones, Adv. Synth. Catal. 2010, 352, 2455-2458, 2010, 通讯作者
(52) Synthesis and Physicochemical Properties of Bis(fluoroalkanesulfonyl)imide-based Ionic Liquids, Eur. J. Inorg. Chem. 2010, 3419-3422, 2010, 通讯作者
(53) Electrophilic Reaction of Ag(III) N-Confused Porphyrin with Alcohols, J. Org. Chem. 2010, 75, 3511-3514, 2010, 通讯作者
(54) Determination of pKa Values of Fluoroalkanesulfonamides and Investigation of Their Nucleophilicity, J. Fluorine Chem. 2010, 131, 761-766, 2010, 通讯作者
(55) New Electrophilic Bromodifluoromethylation and Pentafluoroethylation Reagents, Synlett 2010, 1089-1092, 2010, 通讯作者
(56) One-pot synthesis of arylfluoroalkylsulfoxides and study of their anomalous 19F NMR behavior, J. Fluorine Chem. 2010, 131, 433-438, 2010, 通讯作者
(57) Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water, Green Chem. 2009, 11, 1750-1753, 2009, 通讯作者
(58) Unexpected Reactions of Push-Pull N-Heterocyclic Carbene Derived from N-(4-methoxyphenyl)-N-(4-nitrophenyl)-imidazolium Chloride, Synlett 2009, 2305-2308, 2009, 通讯作者
(59) Reaction of difluorocarbene with propargyl esters and efficient synthesis of difluorocyclopropyl ketones, Tetrahedron 2009, 65, 6320-6324, 2009, 通讯作者
(60) A mild hydrodehalogenation of fluoroalkyl halides, J. Fluorine Chem. 2009, 130, 671-673, 2009, 通讯作者
(61) The Oxidation of Ni(II) N-Confused Porphyrins (NCPs) with Azo Radical Initiators and an Unexpected Intramolecular Nucleophilic Substitution Reaction via a Proposed Ni(III) NCP Intermediate, Chem. Commun. 2009, 3732-3734, 2009, 通讯作者
(62) A novel pyrrolidinium ionic liquid with 1,1,2,2-tetrafluoro-2-(1,1,2,2- tetrafluoroethoxy)ethanesulfonate anion as a recyclable reaction medium and efficient catalyst for Friedel-Crafts alkylations of indoles with nitroalkenes, J. Fluorine Chem. 2009, 130, 394-398, 2009, 通讯作者
(63) Synthesis and Reactions of the First Fluoroalkylated Ni(II) N-Confused Porphyrins, Chem. Commun. 2008, 5435-5437, 2008, 通讯作者
(64) Ring-Opening Reactions of Difluoro(methylene)cyclopropanes with Halogens and Amines, J. Org. Chem. 2008, 73, 8598-8600, 2008, 通讯作者
(65) Novel low-melting salts with donor-acceptor substituents as targets for second-order nonlinear optical applications, Chem. Commun. 2008, 5016-5018, 2008, 通讯作者
(66) 1,3-Dipolar Cycloaddition of Difluoro(methylene)cyclopropanes with Nitrones: Efficient synthesis of 3,3-Difluorinated Tetrahydropyridinols, Synlett 2008, 1989-1992, 2008, 通讯作者
(67) Reactions of HMPA with hexafluorobenzene, pentafluorochlorobenzene and pentafluorophenol, J. Fluorine Chem. 2008, 129, 424-428, 2008, 通讯作者
(68) Highly regio- and stereoselective Diels-Alder cycloaddition of difluoro(methylene)cyclopropanes, Eur. J. Org. Chem. 2008, 1101-1106, 2008, 通讯作者
发表著作
   

科研活动

   
科研项目
( 1 ) 高张力有机小分子——二氟(亚甲基)环丙烷的合成与反应研究, 主持, 国家级, 2010-01--2012-12
( 2 ) 氟烷基锍盐的制备与反应研究, 主持, 国家级, 2012-01--2015-12
( 3 ) 单氟烯烃的合成与反应, 主持, 国家级, 2015-01--2018-12
( 4 ) 高效稀土萃取剂的分子设计、合成与性能, 主持, 国家级, 2012-01--2016-08
参与会议
(1)Conversion Between Difluorocarbene And Difluoromethylene Ylide   第21届国际氟化学会议   2015-08-23
(2)Synthesis and Reaction of Some Fluorine-containing Phosphonium Salts    第十七届欧洲氟化学会议   2013-07-21

合作情况

   
项目协作单位
   

指导学生

已指导学生

辜伟鹏  02  19132  

杭晓春  01  19132  

蔡吉  01  19132  

蒋华卫  01  19132  

郝菲  02  19132  

林锦鸿  01  19132  

张成潘  01  19132  

朱志强  01  19132  

李强  02  19132  

张禾  01  19132  

于静  02  63220  

季云龙  01  19132  

姜延华  02  63220  

郑剑  01  19132  

邓祖勇  01  19132  

现指导学生

于蛟  02  19132  

罗佳佳  02  19132  

邓晓云  01  19132  

段亚亚  01  19132  

张维  02  19132  

张敏  02  19132  

陈佳  01  19132  

张唯  01  19132