天然产物化学
糖化学生物学
杂环化学

   

070303-有机化学
070321-化学生物学

糖化学生物学，药物化学
天然产物全合成

1992-07--1995-06   中国科学院化学研究所   理学博士学位
1989-09--1992-06   中国科学院化学研究所   理学硕士学位
1981-09--1985-06   江西师范大学   理学学士学位

1996年－1999年英国桑德兰大学生命学院博士后；
1999年－2001年英国牛津大学有机化学系(Dyson Perrins Laboratory)博士后

1985年－1989年上饶师专化学系助教 

​1995年－1996年中国科学院化学所助理研究员 

1996年－1999年英国Sunderland大学生命学院, 博士后

1999年－2001年,英国牛津大学, 博士后

2001年7月中国科学院“****”，中科院分子识别与功能重点实验室，研究员，博士生导师 

2012-01-01-今,国家单糖化学合成工程技术研究中心, 中心副主任，技术委员会委员

药物化学

   

[1] 俞初一, 王绪昆, 贾月梅. N-OH谷氨酰胺衍生物及其制备方法与应用. CN: CN115960014A, 2023-04-14.

[2] 俞初一, 陆甜甜, 李意羡, 贾月梅, 程宾, 加藤敦. C5枝化的1-脱氧野尻霉素衍生物及其制备方法和应用. CN: CN115433119A, 2022-12-06.

[3] 俞初一, 訾冬, 贾月梅, 李意羡, 加藤敦. 多羟基吡咯烷类化合物及其制备方法和应用. CN: CN114656391A, 2022-06-24.

[4] 俞初一, 訾冬, 贾月梅, 李意羡, 加藤敦. 多羟基吡咯烷类化合物及其制备方法和应用. 202210333880.9, 2022-03-30.

[5] 俞初一, 王俊哲, 李意羡, 贾月梅. 具有糖苷酶抑制活性的化合物及其盐和水合物和其应用. 202111453692.1, 2021-12-02.

[6] 俞初一, 李意羡, 范玉凯, 吕大超, 贾月梅. 5-溴-6-氯-3-羟基吲哚-2-甲酸甲酯化合物及其制备方法和应用. CN: CN111393352A, 2020-07-10.

[7] 俞初一, 杨林丰, 贾月梅, 李意羡, 加藤敦. 化合物及其制备方法与应用、糖苷酶抑制剂. CN: CN110128315A, 2019-08-16.

[8] 俞初一, 程宾, 贾月梅, 李意羡, 加藤敦. C4枝化的多羟基吡咯烷类化合物及其制备方法和应用. CN: CN106966943A, 2017-07-21.

[9] 俞初一, 郭斯阳, 贾月梅, 李意羡. 一种蓖麻油酸甲酯的制备方法. CN: CN106906051A, 2017-06-30.

[10] 俞初一, 宋营营, 贾月梅, 李意羡, 加藤敦. 多羟基吡咯烷类化合物及其制备方法和应用. CN: CN106349141A, 2017-01-25.

[11] 俞初一, 吴庆昆, 李意羡, 加藤敦. 一种小构树碱类似物及其制备方法和糖苷酶抑制剂与应用. CN: CN106117101A, 2016-11-16.

[12] 俞初一, 贾月梅, 李意羡, 郭斯阳. 偶氮苯甲酸类化合物及其制备方法和应用. CN: CN105985259A, 2016-10-05.

[13] 俞初一, 钱宝琛, 胡祥国. 吲哚里西啶亚氨基糖及其前体化合物和它们的制备方法与应用. CN: CN105732620A, 2016-07-06.

[14] 俞初一, 王洪耀, 贾月梅, 李意羡. 一种制备打碗花精及其中间体的方法. CN: CN105622459A, 2016-06-01.

[15] 俞初一, 钱宝琛, 宋营营, 贾月梅, 李意羡, 加藤敦. 苦马豆素及其中间体的制备方法和苦马豆素衍生物及其制备方法和应用. CN: CN105541854A, 2016-05-04.

[16] 俞初一, 宋营营, 贾月梅, 李意羡, 加藤敦. 小构树碱类化合物及其制备方法和应用. CN: CN105085357A, 2015-11-25.

[17] 俞初一, 宋营营, 贾月梅, 李意羡, 加藤敦. 小构树碱类化合物及其制备方法和应用. CN: CN105085356A, 2015-11-25.

[18] 俞初一, 赵辉, 贾月梅, 陈伟, 李意羡. 一种柠檬酸三酯类化合物及其制备方法和派立辛的制备方法. CN: CN104876980A, 2015-09-02.

[19] 俞初一, 李意羡, 加藤敦, 赵萱. 单氟代Radicamine化合物及其应用与制备方法. CN: CN104557654A, 2015-04-29.

[20] 俞初一, 徐文远, 贾月梅, 张威, 孙喆. 并环亚氨基糖化合物及其中间体和药物及其制备方法和应用. CN: CN103467470A, 2013-12-25.

[21] 俞初一, 朱建设, 贾月梅, 陈伟, 李意羡. 一种Pochonicine类似物或其药学上可接受的盐及其应用. CN: CN103435619A, 2013-12-11.

[22] 俞初一, 胡祥国, 贾月梅, 江新涛, 余官能, 章晓炜, 杨锦飞, 邱曾烨, 赵文博. 氮杂糖季铵盐化合物及其制备方法与应用. CN: CN103265476A, 2013-08-28.

[23] 俞初一, 胡祥国, 贾月梅, 江新涛, 余官能, 章晓炜, 杨锦飞, 邱曾烨, 赵文博. 一种螺环氮杂糖季铵盐化合物及其制备方法与应用. CN: CN103254120A, 2013-08-21.

[24] 俞初一, 余官能, 贾月梅, 胡祥国, 李意羡. 2,3-二脱氧核糖和2,3-二脱氧-2,3-二脱氢核糖及其前体化合物的制备方法. CN: CN103242277A, 2013-08-14.

[25] 俞初一, 余官能, 贾月梅, 胡祥国, 李意羡. 1-O-烷基-2,3-二脱氧-2,3-二脱氢-5-O-(烷基硅基)-呋喃糖的制备方法和应用. CN: CN103242405A, 2013-08-14.

[26] 俞初一, 赵文博, 贾月梅, 胡祥国. 七元环多羟基硝酮及其制备方法和应用. CN: CN102993095A, 2013-03-27.

[27] 俞初一, 赵辉, 贾月梅, 加藤敦. 小钩树碱I和J类似物及其制备方法与应用. CN: CN102775384A, 2012-11-14.

[28] 俞初一, 李意羡, 贾月梅. 氟代多羟基吡咯里西啶及其制备方法与应用. CN: CN102659787A, 2012-09-12.

[29] 俞初一, 李意羡, 贾月梅, 胡祥国. 一种以催化氢化法还原酮糖制备L-核糖的方法. CN: CN102276661A, 2011-12-14.

[30] 俞初一, 李意羡, 贾月梅, 胡祥国. 一种以催化氢化法还原酮糖制备D-阿洛糖的方法. CN: CN102268048A, 2011-12-07.

[31] 俞初一, 张朝兰, 贾月梅, 胡祥国, 加藤敦. 一种多羟基去甲基托品烷类化合物及其制备方法与应用. CN: CN102267993A, 2011-12-07.

[32] 俞初一, 李意羡, 贾月梅. 氟代亚氨基糖化合物及其制备方法与应用. CN: CN102199116A, 2011-09-28.

[33] 俞初一, 穆罕默德雅库, 贾月梅. 一类多环杂环化合物及其制备方法与应用. CN: CN101220030B, 2010-09-15.

[34] 黄志镗, 彭涛, 廖江鹏, 俞初一. 一种合成烯酮缩胺衍生物的方法. CN: CN101041635B, 2010-07-21.

[35] 俞初一, 王武宝, 贾月梅, 李意羡, 芮培欣, 张威. 一种制备六元环多羟基环状硝酮的方法. CN: CN101693686A, 2010-04-14.

[36] 俞初一, 苏加坤, 贾月梅, 李意羡, 芮培欣. 一种含芳基氮杂糖化合物及其制备方法与应用. CN: CN101693708A, 2010-04-14.

[37] 俞初一, 高红云. 一种合成多羟基吡咯啉士啶类生物碱的方法. CN: CN100567298C, 2009-12-09.

[38] 俞初一, 傅 颖, 黄木华, 高红云. 枝化多羟基吡咯烷衍生物及其制备方法与应用. CN: CN100537584C, 2009-09-09.

[39] 俞初一, 乔岩. 一种3－羟基烯酸衍生物及其制备方法与应用. CN: CN100491326C, 2009-05-27.

[40] 俞初一, 张提, 廖江鹏, 黄志镗. 并环碳苷类化合物、碳苷中间体化合物以及它们的制备方法与应用. CN: CN101200470A, 2008-06-18.

[41] 俞初一, 原学宁, 赵梅欣, 黄志镗. 1,2,3－三唑并1,3－二氮杂环化合物及其制备方法与应用. CN: CN101153041A, 2008-04-02.

[42] 俞初一, 苏青云. 一种双羟基高脯氨酸衍生物及其制备方法与应用. CN: CN101070301A, 2007-11-14.

[43] 俞初一, 杨鹏辉, 赵梅欣, 黄志镗. 四氢吡啶酮并1,3－二氮杂环化合物及其制备方法. CN: CN101070321A, 2007-11-14.

[44] 俞初一, 杨鹏辉, 赵梅欣, 黄志镗. 一种含硝基的并环杂环烯酮缩胺及其制备方法. CN: CN101070320A, 2007-11-14.

[45] 俞初一, 廖江鹏, 张提, 黄志镗. 多羟基杂环烯酮缩胺核苷类似物及其制备方法. CN: CN101070336A, 2007-11-14.

[46] 俞初一, 廖江鹏, 张提, 黄志镗. 1,4－二氢吡啶类化合物及其制备方法. CN: CN101058577A, 2007-10-24.

[47] 俞初一, 黄木华, 胡素琴, 胡祥国, 侯研博, 黄志镗. 一种制备多羟基环状硝酮的方法. CN: CN101058557A, 2007-10-24.

[48] 俞初一, 严胜骄, 张提, 黄志镗. 1,2－二氢吡啶衍生物、碳苷中间体及其制备方法与应用. CN: CN101041660A, 2007-09-26.

[49] 黄志镗, 彭涛, 廖江鹏, 俞初一. 一种合成杂环烯酮缩胺衍生物的方法. CN: CN101041636A, 2007-09-26.

[50] 俞初一, 严胜骄, 黄志镗, 虞爱加. 一种环状氟硼酸内盐衍生物及其制备方法与应用. CN: CN101029053A, 2007-09-05.

   

[1] Yang, LinFeng, Zhang, Ming, Shimadate, Yuna, Kato, Atsushi, Hou, TianYang Liu, Li, YiXian, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Design and synthesis of iso-allo-DNJ and L-isoDALDP derivatives: pursuit of potent and selective inhibitors of alpha-glucosidase. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2023, 21(16): 3453-3464, http://dx.doi.org/10.1039/d3ob00404j.
[2] Zi, Dong, Song, YingYing, Lu, TianTian, Kise, Maki, Kato, Atsushi, Wang, JunZhe, Jia, YueMei, Li, YiXian, Fleet, George W J, Yu, ChuYi. Nanomolar beta-glucosidase and beta-galactosidase inhibition by enantiomeric alpha-1-C-alkyl-1,4-dideoxy-1,4-imino-arabinitol derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2023, 247: http://dx.doi.org/10.1016/j.ejmech.2022.115056.
[3] Zi, Dong, Shimadate, Yuna, Wang, JunZhe, Kato, Atsushi, Li, YiXian, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Design, synthesis and glycosidase inhibition of DAB derivatives with C-4 peptide and dipeptide branches. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2023, 21(13): 2729-2741, http://dx.doi.org/10.1039/d3ob00097d.
[4] Wang, XuKun, Jia, YueMei, Li, YiXian, Yu, ChuYi. Total Synthesis of Pseudouridimycin. ORGANIC LETTERS[J]. 2022, 24(2): 511-515, http://dx.doi.org/10.1021/acs.orglett.1c03914.
[5] Wang, JunZhe, Shimadate, Yuna, Kise, Maki, Kato, Atsushi, Jia, YueMei, Li, YiXian, Fleet, George W J, Yu, ChuYi. trans, trans-2-C-Aryl-3,4-dihydroxypyrrolidines as potent and selective β-glucosidase inhibitors: Pharmacological chaperones for Gaucher disease. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2022, 238: 114499-, http://dx.doi.org/10.1016/j.ejmech.2022.114499.
[6] Zhang, Ming, Chen, HongWei, Liu, QingQuan, Gao, FengTeng, Li, YiXian, Hu, XiangGuo, Yu, ChuYi. De Novo Synthesis of Orthogonally-Protected C2-Fluoro Digitoxoses and Cymaroses: Development and Application for the Synthesis of Fluorinated Digoxin. JOURNAL OF ORGANIC CHEMISTRY[J]. 2022, 87(2): 1272-1284, http://dx.doi.org/10.1021/acs.joc.1c02592.
[7] Kato, Atsushi, Nakagome, Izumi, Kanekiyo, Uta, Lu, TianTian, Li, YiXian, Yoshimura, Kosuke, Kishida, Mana, Shinzawa, Kenta, Yoshida, Tomoki, Tanaka, Nobutada, Jia, YueMei, Nash, Robert J, Fleet, George W J, Yu, ChuYi. 5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease. JOURNAL OF MEDICINAL CHEMISTRY[J]. 2022, 65(3): 2329-2341, http://dx.doi.org/10.1021/acs.jmedchem.1c01673.
[8] Wang, Jun-Zhe, Cheng, Bin, Kato, Atsushi, Kise, Maki, Shimadate, Yuna, 贾月梅, 李意羡, George W. J. Fleet, 俞初一. Design, synthesis and glycosidase inhibition of C-4 branched LAB and DAB derivatives. European Journal of Medicinal Chemistry[J]. 2022, 233: 114230-, [9] Kato, Atsushi, Nakagome, Izumi, Yoshimura, Kosuke, Kanekiyo, Uta, Kishida, Mana, Shinzawa, Kenta, Lu, TianTian, Li, YiXian, Nash, Robert J, Fleet, George W J, Tanaka, Nobutada, Yu, ChuYi. Introduction of C-alkyl branches to l-iminosugars changes their active site binding orientation. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2022, 20(36): 7250-7260, [10] YiXian Li, JunZhe Wang, Yuna Shimadate, Maki Kise, Atsushi Kato, YueMei Jia, George WJ Fleet, ChuYi Yu. C-6 fluorinated casuarines as highly potent and selective amyloglucosidase inhibitors: Synthesis and structure-activity relationship study. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2022, 244: 114852-, http://dx.doi.org/10.1016/j.ejmech.2022.114852.
[11] Li, YiXian, Wang, JunZhe, Shimadate, Yuna, Kise, Maki, Kato, Atsushi, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Diastereoselective Synthesis, Glycosidase Inhibition, and Docking Study of C-7-Fluorinated Casuarine and Australine Derivatives. JOURNAL OF ORGANIC CHEMISTRY[J]. 2022, 87(11): 7291-7307, http://dx.doi.org/10.1021/acs.joc.2c00485.
[12] Li, YiXian, Wang, JunZhe, Kato, Atsushi, Shimadate, Yuna, Kise, Maki, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Stereocomplementary synthesis of casuarine and its 6-epi-, 7-epi-, and 6,7-diepi-stereoisomers. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2021, 19(43): 9410-9420, http://dx.doi.org/10.1039/d1ob01725j.
[13] Lu, TianTian, Shimadate, Yuna, Cheng, Bin, Kanekiyo, Uta, Kato, Atsushi, Wang, JunZhe, Li, YiXian, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-L-ido-DNJ derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2021, 224: http://dx.doi.org/10.1016/j.ejmech.2021.113716.
[14] Yan, Xin, Shimadate, Yuna, Kato, Atsushi, Li, YiXian, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Synthesis of Pyrrolidine Monocyclic Analogues of Pochonicine and Its Stereoisomers: Pursuit of Simplified Structures and Potent beta-N-Acetylhexosaminidase Inhibition. MOLECULES[J]. 2020, 25(7): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000531833400023.
[15] Yang, LinFeng, Shimadate, Yuna, Kato, Atsushi, Li, YiXian, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Synthesis and glycosidase inhibition of N-substituted derivatives of 1,4-dideoxy-1,4-imino-d-mannitol (DIM). ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2020, 18(5): 999-1011, http://dx.doi.org/10.1039/c9ob02029b.
[16] Zou, Liangjing, Ruan, Yao, Jiang, Wei, Yan, Nan, Liu, DeYong, Yu, ChuYi, Hu, XiangGuo. Switchable Regioselectivity in the Opening of Aziridine by Fluoride: DFT Calculation and Synthesis of Fluorinated Piperidines. CHEMISTRYSELECT[J]. 2019, 4(43): 12683-12688, https://www.webofscience.com/wos/woscc/full-record/WOS:000498799200034.
[17] Wu, QingKun, Kinami, Kyoko, Kato, Atsushi, Li, YiXian, Fleet, George W J, Yu, ChuYi, Jia, YueMei. Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues. MOLECULES[J]. 2019, 24(20): https://doaj.org/article/55ffc8a9900e4cb3a75fe0e9beb990ea.
[18] Yan, Xin, Li, YiXian, Jia, YueMei, Yu, ChuYi. Glycosylated Iminosugars: Isolation, Synthesis and Biological Activities. PROGRESS IN CHEMISTRY[J]. 2019, 31(11): 1472-1508, [19] 闫新, 李意羡, 贾月梅, 俞初一. 糖苷化的亚氨基糖：分离、合成与生物活性. 化学进展[J]. 2019, 31(11): 1472-1508, https://manu56.magtech.com.cn/progchem/CN/10.7536/PC190307.
[20] Li, Yixian, Jia, Yuemei, Yu, Chuyi. Synthesis and Glycosidase Inhibitory Activities of Fluorinated Iminosugars. PROGRESS IN CHEMISTRY[J]. 2018, 30(5): 586-600, https://www.webofscience.com/wos/woscc/full-record/WOS:000439521900012.
[21] Yang, Kunhao, Li, Zhongqiu, Lv, Yueguang, Yu, Chuyi, Wang, Peilong, Su, Xiaoou, Wu, Li, He, Yujian. Graphene and AuNPs based electrochemical aptasensor for ultrasensitive detection of hydroxylated polychlorinated biphenyl. ANALYTICA CHIMICA ACTA[J]. 2018, 1041: 94-101, http://dx.doi.org/10.1016/j.aca.2018.08.047.
[22] 李意羡, 贾月梅, 俞初一. 氟代亚氨基糖的合成与糖苷酶抑制活性. 化学进展[J]. 2018, 30(5): 586-600, http://lib.cqvip.com/Qikan/Article/Detail?id=675387087.
[23] Hu, Ludan, Xu, Huifen, Yang, Qin, Deng, Zhihong, Yu, ChuYi, Peng, Yiyuan. Quinazoline-directed selective ortho-iodination for the synthesis of 2-(2-iodoaryl)-4-arylquinazolines. JOURNAL OF ORGANOMETALLIC CHEMISTRY[J]. 2017, 843: 20-25, http://dx.doi.org/10.1016/j.jorganchem.2017.05.025.
[24] Cheng, Bin, Li, YiXian, Jia, YueMei, Yu, ChuYi. Concise synthesis of 1-epi-castanospermine. CHINESE CHEMICAL LETTERS[J]. 2017, 28(8): 1688-1692, http://dx.doi.org/10.1016/j.cclet.2017.05.013.
[25] Fang, Zheng, Hu, WenLi, Liu, DeYong, Yu, ChuYi, Hu, XiangGuo. Synthesis of tetrazines from gem-difluoroalkenes under aerobic conditions at room temperature. GREEN CHEMISTRY[J]. 2017, 19(5): 1299-1302, https://www.webofscience.com/wos/woscc/full-record/WOS:000396144200016.
[26] Liu, Qingju, Zhao, Chuanfang, Huang, Jincheng, Chen, Li, Yang, Kunhao, Gong, Lingling, Du, Yuguo, Yu, Chuyi, Wu, Li, Li, Xiangjun, He, Yujian. Enantioselectivity of D-amino acid oxidase in the presence of ionic liquids. RSC ADVANCES[J]. 2017, 7(54): 34110-34117, https://www.webofscience.com/wos/woscc/full-record/WOS:000405279100052.
[27] Cheng, Bin, Hirokami, Yuki, Li, YiXian, Kato, Atsushi, Jia, YueMei, Yu, ChuYi. Synthesis and glycosidase inhibition of C-7 modified casuarine derivatives. CHINESECHEMICALLETTERS[J]. 2017, 28(8): 1701-1704, http://dx.doi.org/10.1016/j.cclet.2017.06.016.
[28] Wu, QingKun, Li, YiXian, Jia, YueMei, Yu, ChuYi. Synthesis of a novel C-branched polyhydroxylated cyclic nitrone. CHINESE CHEMICAL LETTERS[J]. 2017, 28(4): 909-912, http://dx.doi.org/10.1016/j.cclet.2016.12.033.
[29] Li, YiXian, Iwaki, Ren, Kato, Atsushi, Jia, YueMei, Fleet, George W J, Zhao, Xuan, Xiao, Min, Yu, ChuYi. Fluorinated Radicamine A and B: Synthesis and Glycosidase Inhibition. EUROPEANJOURNALOFORGANICCHEMISTRY[J]. 2016, 2016(7): 1429-1438, [30] Li, YiXian, Kinami, Kyoko, Hirokami, Yuki, Kato, Atsushi, Su, JiaKun, Jia, YueMei, Fleet, George W J, Yu, ChuYi. Gem-difluoromethylated and trifluoromethylated derivatives of DMDP-related iminosugars: synthesis and glycosidase inhibition. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(7): 2249-2263, http://dx.doi.org/10.1039/c5ob02474a.
[31] Song, YingYing, Kinami, Kyoko, Kato, Atsushi, Jia, YueMei, Li, YiXian, Fleet, George W J, Yu, ChuYi. First total synthesis of (+)-broussonetine W: glycosidase inhibition of natural product & analogs. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(22): 5157-5174, [32] Wang, HongYao, Kato, Atsushi, Kinami, Kyoko, Li, YiXian, Fleet, George W J, Yu, ChuYi. Concise synthesis of calystegines B-2 and B-3 via intramolecular Nozaki-Hiyama-Kishi reaction. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(21): 4885-4896, http://dx.doi.org/10.1039/c6ob00697c.
[33] Liu, Zilei, Jenkinson, Sarah F, Kato, Atsushi, Nakagawa, Shinpei, Wormald, Mark R, Yu, ChuYi, Fleet, George W J. 3-Azidoazetidines as the first scaffolds for beta-amino azetidine carboxylic acid peptidomimetics: azetidine iminosugars containing an acetamido group do not inhibit beta-N-acetylhexosaminidases. TETRAHEDRON-ASYMMETRY[J]. 2016, 27(17-18): 872-881, http://ir.iccas.ac.cn/handle/121111/35282.
[34] Jiang, Xin, Yang, Qin, Yuan, Jianjun, Deng, Zhihong, Mao, Xuechun, Peng, Yiyuan, Yu, Chuyi. Rhodium-catalyzed tandem C-H activation and aza-Michael addition of 2-arylquinazolin-4-ones with acrylates for the synthesis of pyrrolo2,1-bquinazolin-9(1H)-one derivatives. TETRAHEDRON[J]. 2016, 72(9): 1238-1243, http://dx.doi.org/10.1016/j.tet.2016.01.020.
[35] Qian, BaoChen, Kamori, Akiko, Kinami, Kyoko, Kato, Atsushi, Li, YiXian, Fleet, George W J, Yu, ChuYi. Epimerization of C5 of an N-hydroxypyrrolidine in the synthesis of swainsonine related iminosugars. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2016, 14(19): 4488-4498, http://dx.doi.org/10.1039/c6ob00531d.
[36] Li, YiXian, Shimada, Yousuke, Sato, Kasumi, Kato, Atsushi, Zhang, Wei, Jia, YueMei, Fleet, George W J, Xiao, Min, Yu, ChuYi. Synthesis and Glycosidase Inhibition of Australine and Its Fluorinated Derivatives. ORGANIC LETTERS[J]. 2015, 17(3): 716-719, https://www.webofscience.com/wos/woscc/full-record/WOS:000349274200082.
[37] Kato, Atsushi, Zhang, ZhaoLan, Wang, HongYao, Jia, YueMei, Yu, ChuYi, Kinami, Kyoko, Hirokami, Yuki, Tsuji, Yutaro, Adachi, Isao, Nash, Robert J, Fleet, George W J, Koseki, Jun, Nakagome, Izumi, Hirono, Shuichi. Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal alpha-Glucosidases: Binding Conformation and Interaction for ntSI. JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 80(9): 4501-4515, http://ir.iccas.ac.cn/handle/121111/28074.
[38] Li, YiXian, Shimada, Yousuke, Adachi, Isao, Kato, Atsushi, Jia, YueMei, Fleet, George W J, Xiao, Min, Yu, ChuYi. Fluorinated and Conformationally Fixed Derivatives of L-HomoDMDP: Synthesis and Glycosidase Inhibition. JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 80(10): 5151-5158, http://ir.iccas.ac.cn/handle/121111/28138.
[39] YiXian Li Yousuke Shimada Kasumi Sato Atsushi Kato Wei Zhang YueMei Jia George W J Fleet Min Xiao and ChuYi Yu. Synthesis and Glycosidase Inhibition of Australine and Its Fluorinated Derivatives. ORG. LETT.[J]. 2015, 17(3): 716-719, http://ir.iccas.ac.cn/handle/121111/28699.
[40] Liu, Zilei, Jenkinson, Sarah F, Vermaas, Tom, Adachi, Isao, Wormald, Mark R, Hata, Yukako, Kurashima, Yukiko, Kaji, Akira, Yu, ChuYi, Kato, Atsushi, Fleet, George W J. 3-Fluoroazetidinecarboxylic Acids and trans,trans-3,4-Difluoroproline as Peptide Scaffolds: Inhibition of Pancreatic Cancer Cell Growth by a Fluoroazetidine Iminosugar. JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 80(9): 4244-4258, http://ir.iccas.ac.cn/handle/121111/28081.
[41] Ayers, Benjamin J, Glawar, Andreas F G, Martinez, R Fernando, Ngo, Nigel, Liu, Zilei, Fleet, George W J, Butters, Terry D, Nash, Robert J, Yu, ChuYi, Wormald, Mark R, Nakagawa, Shinpei, Adachi, Isao, Kato, Atsushi, Jenkinson, Sarah F. Nine of 16 Stereoisomeric Polyhydroxylated Proline Amides Are Potent beta-N-Acetylhexosaminidase Inhibitors. JOURNAL OF ORGANIC CHEMISTRY[J]. 2014, 79(8): 3398-3409, https://www.webofscience.com/wos/woscc/full-record/WOS:000334823800010.
[42] Xu, WenYuan, Iwaki, Ren, Jia, YueMei, Zhang, Wei, Kato, Atsushi, Yu, ChuYi. NHC-mediated cross-coupling of sugar-derived cyclic nitrones with enals: general and efficient synthesis of polyhydroxylated pyrrolizidines and indolizidines. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2013, 11(28): 4622-4639, https://www.webofscience.com/wos/woscc/full-record/WOS:000322059100009.
[43] Zhao, WenBo, Nakagawa, Shinpei, Kato, Atsushi, Adachi, Isao, Jia, YueMei, Hu, XiangGuo, Fleet, George W J, Wilson, Francis X, Horne, Graeme, Yoshihara, Akihide, Izumori, Ken, Yu, ChuYi. General Synthesis of Sugar-Derived Azepane Nitrones: Precursors of Azepane Iminosugars. JOURNAL OF ORGANIC CHEMISTRY[J]. 2013, 78(7): 3208-3221, https://www.webofscience.com/wos/woscc/full-record/WOS:000317327800040.
[44] WenYuan Xu, Ren Iwaki, YueMei Jia, Wei Zhang, Atsushi Kato, ChuYi Yu. NHC-mediated cross-coupling of sugar-derived cyclic nitrones with enals: general and efficient synthesis of polyhydroxylated pyrrolizidines and indolizidines. ORG. BIOMOL. CHEM.[J]. 2013, 11(28): 4622-4639, http://ir.iccas.ac.cn/handle/121111/28696.
[45] Hui Zhao, Atsushi Kato, Kasumi Sato, YueMei Jia, ChuYi Yu. Total synthesis and glycosidase inhibition of broussonetine I and j2. J. ORG. CHEM.[J]. 2013, 78(16): 7896-7902, http://ir.iccas.ac.cn/handle/121111/28695.
[46] Huang, MuHua, Li, YiXian, Jia, YueMei, Yu, ChuYi. General Intermediates for the Synthesis of 6-C-Alkylated DMDP-Related Natural Products. MOLECULES[J]. 2013, 18(6): 6723-6733, http://ir.iccas.ac.cn/handle/121111/28697.
[47] JianShe Zhu, Shinpei Nakagawa, Wei Chen, Graeme Horne, Renate van Well, Atsushi Kato, ChuYi Yu, Isao Adachi, YueMei Jia, XiangGuo Hu, George W J Fleet, Francis X Wilson, Teruhiko Nitoda. Synthesis of Eight Stereoisomers of Pochonicine: Nanomolar Inhibition of β-N-Acetylhexosaminidases. J. ORG. CHEM.[J]. 2013, 78(20): 10298-10309, http://ir.iccas.ac.cn/handle/121111/28691.
[48] WenBo Zhao, Shinpei Nakagawa, Atsushi Kato, Akihide Yoshihara, Ken Izumori, ChuYi Yu, Isao Adachi, YueMei Jia, XiangGuo Hu, George W J Fleet, Francis X Wilson, Graeme Horne. General Synthesis of Sugar-Derived Azepane Nitrones: Precursors of Azepane Iminosugars. J. ORG. CHEM.[J]. 2013, 78(7): 3208-3221, http://ir.iccas.ac.cn/handle/121111/28692.
[49] Zhao, Hui, Zhao, WenBo, Zhu, JianShe, Jia, YueMei, Yu, ChuYi. An Efficient Synthesis of Aldohexose-Derived Piperidine Nitrones: Precursors of Piperidine Iminosugars. MOLECULES[J]. 2013, 18(5): 6021-6034, http://ir.iccas.ac.cn/handle/121111/28693.
[50] Zhu, JianShe, Nakagawa, Shinpei, Chen, Wei, Adachi, Isao, Jia, YueMei, Hu, XiangGuo, Fleet, George W J, Wilson, Francis X, Nitoda, Teruhiko, Horne, Graeme, van Well, Renate, Kato, Atsushi, Yu, ChuYi. Synthesis of Eight Stereoisomers of Pochonicine: Nanomolar Inhibition of beta-N-Acetylhexosaminidases. JOURNAL OF ORGANIC CHEMISTRY[J]. 2013, 78(20): 10298-10309, http://dx.doi.org/10.1021/jo401694e.
[51] Zhang, Ning, Li, Yafeng, Zhou, Yueming, Hou, Jian, He, Qing, Hu, XiangGuo, Jia, YueMei, Yu, ChuYi, Nie, Zongxiu. Rapid detection of polyhydroxylated alkaloids in mulberry using leaf spray mass spectrometry. ANALYTICAL METHODS[J]. 2013, 5(10): 2455-2460, https://www.webofscience.com/wos/woscc/full-record/WOS:000318314700003.
[52] Zhao, Hui, Wang, WuBao, Nakagawa, Shinpei, Jia, YueMei, Hu, XiangGuo, Fleet, George W J, Wilson, Francis X, Nash, Robert J, Kato, Atsushi, Yu, ChuYi. Novel 2-aryl-3,4,5-trihydroxypiperidines: Synthesis and glycosidase inhibition. CHINESE CHEMICAL LETTERS[J]. 2013, 24(12): 1059-1063, http://lib.cqvip.com/Qikan/Article/Detail?id=48218804.
[53] Zhao, Hui, Kato, Atsushi, Sato, Kasumi, Jia, YueMei, Yu, ChuYi. Total Synthesis and Glycosidase Inhibition of Broussonetine I and J(2). JOURNAL OF ORGANIC CHEMISTRY[J]. 2013, 78(16): 7896-7902, https://www.webofscience.com/wos/woscc/full-record/WOS:000323362600010.
[54] 张宁, 李亚峰, 周跃明, 侯剑, 何清, 胡祥国, 贾月梅, 俞初一, 聂宗秀. 叶喷雾质谱法快速检测桑叶中的多羟基生物碱. ANAL. METH.[J]. 2013, 2455-2460, http://ir.iccas.ac.cn/handle/121111/27207.
[55] LenaghSnow, Gabriel M J, Araujo, Noelia, Jenkinson, Sarah F, Martinez, R Fernando, Shimada, Yousuke, Yu, ChuYi, Kato, Atsushi, Fleet, George W J. Azetidine Iminosugars from the Cyclization of 3,5-Di-O-triflates of alpha-Furanosides and of 2,4-Di-O-triflates of beta-Pyranosides Derived from Glucose. ORGANIC LETTERS[J]. 2012, 14(8): 2142-2145, http://dx.doi.org/10.1021/ol300669v.
[56] LenaghSnow, Gabriel M J, Araujo, Noelia, Jenkinson, Sarah F, Rutherford, Catherine, Nakagawa, Shinpei, Kato, Atsushi, Yu, ChuYi, WeymouthWilson, Alexander C, Fleet, George W J. Inhibition of Nonmammalian Glycosidases by Azetidine Iminosugars Derived from Stable 3,5-Di-O-triflates of Pentoses. ORGANIC LETTERS[J]. 2011, 13(21): 5834-5837, http://dx.doi.org/10.1021/ol2024482.
[57] ZhaoLan Zhang Shinpei Nakagawa Atsushi Kato YueMei Jia XiangGuo Hua and ChuYi Yu. A Concise Stereoselective Synthesis of (-)-Erycibelline. ORG. BIOMOL. CHEM.[J]. 2011, 9(22): 7713-7719, http://ir.iccas.ac.cn/handle/121111/28688.
[58] Zhang, Wei, Sato, Kasumi, Kato, Atsushi, Jia, YueMei, Hu, XiangGuo, Wilson, Francis X, van Well, Renate, Horne, Graeme, Fleet, George W J, Nash, Robert J, Yu, ChuYi. Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization. ORGANIC LETTERS[J]. 2011, 13(16): 4414-4417, http://dx.doi.org/10.1021/ol201749c.
[59] Wei Zhang Kasumi Sato Atsushi Kato YueMei Jia XiangGuo Hu Francis X Wilson Renate van Well Graeme Horne George W J Fleet Robert J Nash and ChuYi Yu. Synthesis of Fully Substituted Polyhydroxylated Pyrrolizidines via Cope-House Cyclization. ORG. LETT.[J]. 2011, 13(16): 4414-4417, http://ir.iccas.ac.cn/handle/121111/28689.
[60] Nash, Robert J, Kato, Atsushi, Yu, ChuYi, Fleet, George W J. Iminosugars as therapeutic agents: recent advances and promising trends. FUTURE MEDICINAL CHEMISTRYnull. 2011, 3(12): 1513-1521, https://www.webofscience.com/wos/woscc/full-record/WOS:000295491900012.
[61] YiXian Li MuHua Huang Yukiko Yamashita Atsushi KatoYueMei Jia WuBao Wang George W J Fleet Robert J Nash and ChuYi Yu. L-DMDP, L-homoDMDP and Their C-3 Fluorinated Derivatives: Synthesis and Glycosidase-Inhibition. ORG. BIOMOL. CHEM.[J]. 2011, 9(9): 3405-3414, http://ir.iccas.ac.cn/handle/121111/28685.
[62] Zhang, ZhaoLan, Nakagawa, Shinpei, Kato, Atsushi, Jia, YueMei, Hu, XiangGuo, Yu, ChuYi. A concise stereoselective synthesis of (-)-erycibelline. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2011, 9(22): 7713-7719, http://dx.doi.org/10.1039/c1ob06244a.
[63] Li, YiXian, Huang, MuHua, Yamashita, Yukiko, Kato, Atsushi, Jia, YueMei, Wang, WuBao, Fleet, George W J, Nash, Robert J, Yu, ChuYi. L-DMDP, L-homoDMDP and their C-3 fluorinated derivatives: synthesis and glycosidase-inhibition. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2011, 9(9): 3405-3414, http://dx.doi.org/10.1039/c0ob01063d.
[64] Zhao, Hui, Zeng, AiQun, Liao, WeiLin, Jia, YueMei, Wang, LiBen, Huang, ZhiTang, Yu, ChuYi. REACTIONS OF HETEROCYCLIC KETENE AMINALS WITH ACRYLONITRILE: AN EFFICIENT SYNTHESIS OF DIHYDROPYRIDINE-FUSED 1,3-DIAZAHETEROCYCLES. HETEROCYCLES[J]. 2010, 82(1): 619-629, http://dx.doi.org/10.3987/COM-10-S(E)34.
[65] Hu, XiangGuo, Jia, YueMei, Xiang, Junfeng, Yu, ChuYi. Exploratory Studies en Route to 5-Alkyl-Hyacinthacines: Synthesis of 5-epi-(-)-Hyacinthacine A(3) and (-)-Hyacinthacine A(3). SYNLETT[J]. 2010, 982-986, http://www.corc.org.cn/handle/1471x/2407118.
[66] Xu, WenYuan, Jia, YueMei, Yang, JingKui, Huang, ZhiTang, Yu, ChuYi. Reactions of Heterocyclic Ketene Aminals with 2-3-Oxoisobenzofuran-1(3H)-ylidenemalononitrile: Synthesis of Novel Polyfunctionalized 1,4-Dihydropyridine-Fused 1,3-Diazaheterocycles. SYNLETT[J]. 2010, 1682-1684, http://www.corc.org.cn/handle/1471x/2414725.
[67] Zhang, Ti, Yu, ChuYi, Huang, ZhiTang, Jia, YueMei. Solvent-Free and Stereoselective Synthesis of C-Glycosides by Michael-Type Addition of Enamino Esters to 2-Nitro-D-glucal. SYNLETT[J]. 2010, 2174-2178, http://dx.doi.org/10.1055/s-0030-1258498.
[68] WenYuan Xu, YueMei Jia, JingKui Yang, ZhiTang Huang, ChuYi Yu. Reactions of Heterocyclic Ketene Aminals with 2-(3-Oxoisobenzofuran-1(3H)-ylidene) Malononitrile: An Efficient Synthesis of Polyfunctionalized Spiro 1,4-Dihydropyridine-Fused 1,3-Diazaheterocycles. SYNLETT[J]. 2010, 2010(11): 1682-1684, http://ir.iccas.ac.cn/handle/121111/28681.
[69] Kato, Atsushi, Hollinshead, Jackie, Yamashita, Yukiko, Nakagawa, Shinpei, Koike, Yuriko, Adachi, Isao, Yu, ChuYi, Fleet, George W J, Nash, Robert J. An alpha-glucoside of 1,4-dideoxy-1,4-imino-D-lyxitol with an eleven carbon side chain. PHYTOCHEMISTRY LETTERS[J]. 2010, 3(4): 230-233, https://www.webofscience.com/wos/woscc/full-record/WOS:000287849600014.
[70] Best, Daniel, Chairatana, Phoom, Glawar, Andreas F G, Crabtree, Elizabeth, Butters, Terry D, Wilson, Francis X, Yu, ChuYi, Wang, WuBao, Jia, YueMei, Adachi, Isao, Kato, Atsushi, Fleet, George W J. Synthesis of 2-acetamido-1,2-dideoxy-D-galacto-nojirimycin DGJNAc from D-glucuronolactone: the first sub-micromolar inhibitor of alpha-N-acetylgalactosaminidases. TETRAHEDRON LETTERS[J]. 2010, 51(17): 2222-2224, https://www.webofscience.com/wos/woscc/full-record/WOS:000276588100003.
[71] Su, JiaKun, Jia, YueMei, He, Ruirui, Rui, PeiXin, Han, Nanyin, He, Xihui, Xiang, Junfeng, Chen, Xin, Zhu, Jinghua, Yu, ChuYi. A Rapid Synthesis of 2-Aryl Polyhydroxylated Pyrrolidines. SYNLETT[J]. 2010, 2010(11): 1609-1616, http://dx.doi.org/10.1055/s-0029-1258085.
[72] XiangGuo Hu, YueMei Jia, Junfeng Xiang, ChuYi Yu. Exploratory studies en route to 5-alkyl-: synthesis of 5-epi-(-)-hyacinthacine A3 and (-)-hyacinthacine A3. SYNLETT[J]. 2010, 2010(6): 982-986, http://ir.iccas.ac.cn/handle/121111/28680.
[73] Michalik, Agnieszka, Hollinshead, Jacqueline, Jones, Laurence, Fleet, George W J, Yu, ChuYi, Hu, XiangGuo, van Well, Renate, Horne, Graeme, Wilson, Francis X, Kato, Atsushi, Jenkinson, Sarah F, Nash, Robert J. Steviamine, a new indolizidine alkaloid from Stevia rebaudiana. PHYTOCHEMISTRY LETTERS[J]. 2010, 3(3): 136-138, http://dx.doi.org/10.1016/j.phytol.2010.04.004.
[74] Wang, WuBao, Huang, MuHua, Li, YiXian, Rui, PeiXin, Hu, XiangGuo, Zhang, Wei, Su, JiaKun, Zhang, ZhaoLan, Zhu, JianShe, Xu, WeiHua, Xie, XianQing, Jia, YueMei, Yu, ChuYi. A Practical Synthesis of Sugar-Derived Cyclic Nitrones: Powerful Synthons for the Synthesis of Iminosugars. SYNLETT[J]. 2010, 488-492, http://ir.iccas.ac.cn/handle/121111/28679.
[75] Hu, XiangGuo, Bartholomew, Barbara, Nash, Robert J, Wilson, Francis X, Fleet, George W J, Nakagawa, Shinpei, Kato, Atsushi, Jia, YueMei, van Well, Renate, Yu, ChuYi. Synthesis and Glycosidase Inhibition of the Enantiomer of (-)-Steviamine, the First Example of a New Class of Indolizidine Alkaloid. ORGANIC LETTERS[J]. 2010, 12(11): 2562-2565, https://www.webofscience.com/wos/woscc/full-record/WOS:000278062600032.
[76] Deng, Jieli, Sheng, Zhonghan, Zhou, Kai, Duan, Mingxing, Yu, Chuyi, Jiang, Long. Construction of Effective Receptor for Recognition of Avian Influenza H5N1 Protein HA1 by Assembly of Monohead Glycolipids on Polydiacetylene Vesicle Surface. BIOCONJUGATE CHEMISTRY[J]. 2009, 20(3): 533-537, https://www.webofscience.com/wos/woscc/full-record/WOS:000264389800017.
[77] Thompson, Amber L, Michalik, Agnieszka, Nash, Robert J, Wilson, Francis X, van Well, Renate, Johnson, Peter, Fleet, George W J, Yu, ChuYi, Hu, XiangGuo, Cooper, Richard I, Watkin, David J. Steviamine, a new class of indolizidine alkaloid (1R,2S,3R,5R,8aR)-3-hydroxymethyl-5-methyloctahydroindolizine-1,2-diol hydrobromide. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE[J]. 2009, 65(Pt 11): O2904-U2232, https://doaj.org/article/5291fcab05ff425dbeb8474867a68d7c.
[78] Zhang, Ti, Jia, YueMei, Yan, ShengJiao, Yu, ChuYi, Huang, ZhiTang. Synthesis of BF2 complex of 3-methylthio enaminones. ARKIVOC[J]. 2009, 156-170, http://dx.doi.org/10.3998/ark.5550190.0010.e15.
[79] Jenkinson, Sarah F, Cruz, Filipa P, Booth, Kathrine V, Fleet, George W J, Izumori, Ken, Yu, ChuYi, Watkin, David J. 1-deoxy-D-arabinitol. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE[J]. 2008, 64: O1010-U1581, http://dx.doi.org/10.1107/S1600536808012555.
[80] Yaqub, Muhammad, Yu, ChuYi, Jia, YueMei, Huang, ZhiTang. Reactions of Heterocyclic ketene aminals with baylis-hillman acetates: A novel synthesis of tetrahydropyridine-fused 1,3-diazaheterocycles. SYNLETT[J]. 2008, 1357-1360, http://ir.iccas.ac.cn/handle/121111/28673.
[81] Zhou, Qiuju, Xiang, Junfeng, Tang, Yalin, Liao, Jiangpeng, Yu, Chuyi, Du, Hongyan, Yang, Qianfan, Xu, Guangzhi. Interaction of spiro(2R,3R,4S)-4-benzyloxy-2,3-iso-propylidenedioxy-1-oxacyclopentane-5,5 '-(2-nitromethylene-1,3-diazacyclohexane) with bovine serum albumin. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY[J]. 2008, 92(1): 43-47, http://www.corc.org.cn/handle/1471x/2391357.
[82] Zhou, Qiuju, Xiang, Junfeng, Tang, Yalin, Liao, Jiangpeng, Yu, Chuyi, Zhang, Hong, Li, Lin, Yang, Yueyang, Xu, Guangzhi. Investigation on the interaction between a heterocyclic aminal derivative, SBDC, and human serum albumin. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2008, 61(1): 75-80, http://www.corc.org.cn/handle/1471x/2392824.
[83] Li, Lin, Tian, YanHong, Yu, ChuYi, Wang, LiBen. (E)-benzoyl1-(2-hydroxyethyl)imidazolidin-2-ylideneacetonitrile. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE[J]. 2008, 64: O62-U3064, http://dx.doi.org/10.1107/S1600536807055778.
[84] Yu, ChuYi, Yuan, XueNing, Huang, ZhiTang. 9-(4-Methoxybenzoyl)-1,2,3,4-tetrahydro-6H-pyrido1,2-apyrimidin-6-one. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2007, 63: O3186-U3282, https://www.webofscience.com/wos/woscc/full-record/WOS:000248149900315.
[85] Liao, JiangPeng, Zhang, Ti, Yu, ChuYi, Huang, ZhiTang. Reaction of heterocyclic ketene aminals with bis(methylthio)methylene malononitrile: Synthesis of polyfunctionalized pyridine-fused 1,3-diazaheterocycles from heterocyclic ketene aminals. SYNLETT[J]. 2007, 761-764, http://ir.iccas.ac.cn/handle/121111/28672.
[86] Yu, ChuYi, Fu, Ying. 1,4-dideoxy-2,3-O-isopropylidene-N-3-(3-nitrobenzoylamino)benzoyl-1,4-imino-D-talitol. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O3113-O3114, https://www.webofscience.com/wos/woscc/full-record/WOS:000238731900345.
[87] Yu, ChuYi, Gao, HongYun, Qiao, Yan. Methyl 3-(E)-2-(4-bromobenzoylmethyl-idene)imidazolidin-1-ylacrylate. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O5443-O5444, https://www.webofscience.com/wos/woscc/full-record/WOS:000242434600231.
[88] Yu, ChuYi, Yan, ShengJiao, Huang, ZhiTang. 1-(4-chlorophenyl)-2-(imidazolidin-2-ylidene)ethanone. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O2655-O2656, https://www.webofscience.com/wos/woscc/full-record/WOS:000238731900151.
[89] Peng Tao, Yan ShengJiao, Yu ChuYi, Huang ZhiTang. 9-(4-methyoxylbenzoyl)-1,2,3,4,7,8-hexa-hydropyrido1,2-apyrimidin-6-one. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE[J]. 2006, 62(7): O3040-O3041, http://www.corc.org.cn/handle/1471x/2379759.
[90] Yu, ChuYi, Fu, Ying. (2S,3a ' R,4 ' R,5 ' S,6 ' R)-4 ',5 '-isoprolidenedioxy-6 '-(trityloxymethyl)-2 '-oxotetrahydro-1H-spiropyrrolidine-2,3 '-pyrrolo1,2-bisoxazole-1-carbaldehyde. ACTACRYSTALLOGRAPHICASECTIONECRYSTALLOGRAPHICCOMMUNICATIONS[J]. 2006, 62: O3172-O3173, https://www.webofscience.com/wos/woscc/full-record/WOS:000239392200131.
[91] Yu, ChuYi, Gao, HongYun, Qiao, Yan. 1-(2-hydroxyethyl)imidazolidin-2-ylidenemalononitrile. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O5114-O5115, https://www.webofscience.com/wos/woscc/full-record/WOS:000241691500301.
[92] Yu, ChuYi, Qiao, Yan, Gao, HongYun. Allyl 4,6-O-benzylidene-2-deoxy-2-tetrachlorophthalimido-beta-D-glucopyranoside. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O5163-O5164, https://www.webofscience.com/wos/woscc/full-record/WOS:000241691500322.
[93] Yu, ChuYi, Fu, Ying. 1,3 : 4,6-di-O-benzylidene-N-cinnamyl-2,5-dideoxy2,5-imino-L-iditol. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O3115-O3116, https://www.webofscience.com/wos/woscc/full-record/WOS:000238731900346.
[94] Yu, ChuYi, Yang, PengHui, Zhao, MeiXin, Huang, ZhiTang. A novel one-pot reaction of heterocyclic ketene aminals: Synthesis of a small library of tetrahydropyridinone-fused 1,3-diazaheterocycles. SYNLETT[J]. 2006, 1835-1840, http://ir.iccas.ac.cn/handle/121111/28670.
[95] Yu, ChuYi, Qiao, Yan, Gao, HongYun. 1,3,4,6-tetra-O-acetyl-2-deoxy-2-tetrachlorophthalimido-alpha-D-glucopyranoside. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O5123-O5124, https://www.webofscience.com/wos/woscc/full-record/WOS:000241691500305.
[96] Liao, JiangPeng, Zhang, Ti, Yu, ChuYi, Huang, ZhiTang. Ethyl 2-cyano-2-(E)-1-(2-hydroxyethyl)imidazolidin-2-ylideneacetate. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O5161-O5162, https://www.webofscience.com/wos/woscc/full-record/WOS:000241691500321.
[97] Yu, ChuYi, Yan, ShengJiao, Huang, ZhiTang. Ethyl 8-benzoyl-5-oxo-7-phenyl-1,2,3,5,6,7-hexahydroimidazo1,2-apyridine-6-carboxylate. ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS[J]. 2006, 62: O2731-O2733, https://www.webofscience.com/wos/woscc/full-record/WOS:000238731900180.
[98] Peng, Tao, Yu, Chu Yi, Huang, Zhi Tang. Solid-phase synthesis of a novel kind of hydroxylated heterocyclic ketene aminals. CHINESE CHEMICAL LETTERS[J]. 2006, 17(11): 1451-1453, http://lib.cqvip.com/Qikan/Article/Detail?id=23367614.

   

（ 1 ） 与DMDP结构相关的天然亚氨基糖的合成及其生物活性研究, 主持, 国家级, 2013-01--2016-12
（ 2 ） 基于中草药中氮杂糖类化合物的创新药物研究——以GPCRb1/b2AR为靶标的中药活性筛选及创新中药发现, 参与, 国家级, 2013-01--2015-12
（ 3 ） 海上大位移井钻井液关键技术研究, 参与, 国家级, 2012-01--2015-12
（ 4 ） 药物关键中间体的产业化, 主持, 部委级, 2014-01--2015-12
（ 5 ） 单糖药物及其中间体的合成技术研究, 主持, 研究所（学校）, 2013-01--2015-12
（ 6 ） 肿瘤的糖化学生物学前沿研究, 参与, 国家级, 2012-01--2016-12
（ 7 ） 核苷和糖类化合物系列产品的绿色制备, 主持, 院级, 2017-12--2020-11
（ 8 ） 糖化学品合成工艺研究及技术服务, 主持, 院级, 2018-01--2020-12

已指导学生

高红云  博士研究生  070303-有机化学  

苏青云  博士研究生  070303-有机化学  

乔岩  博士研究生  070303-有机化学  

严胜骄  博士研究生  070303-有机化学  

傅颖  博士研究生  070303-有机化学  

黄木华  博士研究生  070303-有机化学  

杨鹏辉  博士研究生  070303-有机化学  

王武宝  博士研究生  070303-有机化学  

苏加坤  博士研究生  070303-有机化学  

胡祥国  博士研究生  070303-有机化学  

张威  博士研究生  070303-有机化学  

李意羡  博士研究生  070303-有机化学  

张朝兰  博士研究生  070303-有机化学  

赵文博  博士研究生  070303-有机化学  

徐文远  博士研究生  070303-有机化学  

朱建设  博士研究生  070303-有机化学  

赵辉  博士研究生  070303-有机化学  

王洪耀  博士研究生  070303-有机化学  

钱宝琛  博士研究生  070303-有机化学  

吴庆昆  博士研究生  070303-有机化学  

宋营营  博士研究生  070303-有机化学  

程宾  博士研究生  070303-有机化学  

现指导学生

闫新  博士研究生  070303-有机化学  

杨林丰  博士研究生  070303-有机化学  

王俊哲  硕士研究生  070303-有机化学  

訾冬  博士研究生  070303-有机化学  

陆甜甜  硕士研究生  070303-有机化学  

王绪昆  博士研究生  070303-有机化学