基本信息

施兴华 研究员/教授(博导) 杰青

电子邮件:shixh@nanoctr.cn 
通信地址:国家纳米科学中心
邮政编码:100190
详情请关注纳米中心主页
http://sourcedb.nanoctr.cas.cn/zw/zxrck/201603/t20160307_4545177.html

研究领域

多尺度理论与计算

表界面力学

生物力学

纳米药物输运

学习经历

2006-08--2010-08   美国Brown University   博士
2001-09--2004-07   中国科学院力学研究所   硕士
1997-09--2004-07   北京大学   学士

教授课程

现代物理学概述
纳米尺度理论与计算
固体力学导论

专利与奖励

中国科学院卢嘉锡青年人才奖(2013),国家优秀青年基金(2014),中国科学院青年创新促进会优秀会员(2017),中国科学院优秀党务工作者(2020),中央和国家机关优秀党务工作者(2021),国家杰出青年基金(2021)


出版信息

   
发表论文
(1) Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues, Science Advances, 2020, 通讯作者
(2) Enhanced transport of shape and rigidity-tuned α-lactalbumin nanotubes across intestinal mucus and cellular barriers, Nano Letters, 2020, 通讯作者
(3) The effect of phenylalanine ligands on the chiral-selective oxidation of glucose on Au (111), Nanoscale, 2020, 通讯作者
(4) Bandgap engineering of few-layered MoS2 with low concentrations of S vacancies, RSC Advances, 2020, 通讯作者
(5) Effect of defects on the electronic structure of a PbI2/MoS2 van der Waals heterostructure: A first-principles study, Science in China Physics, Mechanics & Astronmy, 2020, 通讯作者
(6) Bending induced interlayer shearing, rippling and kink buckling of multilayered graphene sheets, Journal of the Mechanics and Physics of Solids, 2019, 通讯作者
(7) Temperature-and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels, Proceedings of the National Academy of Sciences, 2019, 通讯作者
(8) MOF-derived nitrogen-doped nanoporous carbon for electroreduction of CO 2 to CO: the calcining temperature effect and the mechanism, Nanoscale, 2019, 通讯作者
(9) Aggregation of Amyloid Peptides into Fibrils Driven by Nanoparticles and their Curvature Effect, Physical Chemistry Chemical Physics, 2019, 通讯作者
(10) Recent advances in nanozyme research, Advanced Materials, 2019, 通讯作者
(11) Multiscale Modeling and Simulation of Nano-carriers Delivery through Biological Barriers - A Review, Advanced Theory and Simulations, 2019, 通讯作者
(12) Multiscale Modeling and Simulation of Nano-carriers Delivery through Biological Barriers - A Review, Advanced Theory and Simulations, 2018, 通讯作者
(13) Macroscopic helical chirality and self-motion of hierarchical self-assemblies induced by enantiomeric small molecules, Nature communications, 2018, 通讯作者
(14) Microporous membranes comprising conjugated polymers with rigid backbones enable ultrafast organic-solvent nanofiltration, Nature chemistry, 2018, 第 3 作者
(15) Designed Self-Assembly of Peptides with G-Quadruplex/Hemin DNAzyme into Nanofibrils Possessing Enzyme-Mimicking Active Sites and Catalytic Functions, ACS Catalysis, 2018, 通讯作者
(16) Determination of the packing model of a supramolecular nanofiber via mass-per-length measurement and de novo simulation, Nanoscale, 2018, 通讯作者
(17) Diffusion of rod-like nanoparticles in non-adhesive and adhesive porous polymeric gels, Journal of the Mechanics and Physics of Solids, 2018, 通讯作者
(18) Targeting Endothelial Cell Junctions with Negatively Charged Gold Nanoparticles, Chemistry of Materials, 2018, 通讯作者
(19) Confinement Impact for the Dynamics of Supported Metal Nanoparticles, Small, 2018, 通讯作者
(20) Rapid Transport of Deformation-Tuned Nanoparticles across Biological Hydrogels and Cellular Barriers, Nature Communications, 2018, 通讯作者
(21) 2D Chiroptical Nanostructures for High‐Performance Photooxidants, Advanced Functional Materials, 2018, 通讯作者
(22) 肿瘤及其微环境的力学问题, 力学进展, 2018, 通讯作者
(23) One‐Step Microfluidic Synthesis of Nanocomplex with Tunable Rigidity and Acid‐Switchable Surface Charge for Overcoming Drug Resistance, Small, 2017, 第 6 作者
(24) Molecular dynamics simulation of diffusion of nanoparticles in mucus, Acta Mechanica Solida Sinica, 2017, 通讯作者
(25) The electrochemical performance of super P carbon black in reversible Li/Na ion uptake, Science in China, 2017, 第 4 作者
(26) Self-Assembled DNA/Peptide-Based Nanoparticle Exhibiting Synergistic Enzymatic Activity, ACS Nano, 2017, 通讯作者
(27) Lipid rafts enhance the binding constant of membrane-anchored receptors and ligands, Soft Matter, 2017, 第 3 作者
(28) Rotation-facilitated rapid transport of nanorods in mucosal tissues, Nano Letters, 2016, 通讯作者
(29) Grain boundary and curvature enhanced lithium adsorption on carbon, Carbon, 2016, 第 2 作者
(30) Nonspecific Organelle-Targeting Strategy with Core–Shell Nanoparticles of Varied Lipid Components/Ratios, Analytical Chemistry, 2016, 第 4 作者
(31) A molecular dynamics investigation of the deformation mechanism and shape memory effect of epoxy shape memory polymers, Science China Physics, Mechanics & Astronomy, 2016, 通讯作者
(32) Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake, Advanced Materials, 2015, 通讯作者
(33) Microfluidic synthesis of hybrid nanoparticles with controlled lipid layers: understanding flexibility-regulated cell-nanoparticle interaction, ACS Nano, 2015, 通讯作者
(34) Reformation Capability of Short-Range Order and Their Medium-Range Connections Regulates Deformability of Bulk Metallic Glasses, Scientific Reports, 2015, 通讯作者
(35) Cooperative entry of nanoparticles into the cell, Journal of the Mechanics and Physics of Solids, 2014, 通讯作者
(36) A universal law for cell uptake of one-dimensional nanomaterials, nano letters, 2014, 第 2 作者
(37) Energy barrier for configurational transformation of graphene nanoribbon on nanotube, Theoretical and Applied Mechanics Letters, 2014, 通讯作者
(38) Mechanics of rolling of nanoribbon on tube and sphere, Nanoscale, 2013, 通讯作者
(39) Tunable mechanical behavior of carbon nanoscroll crystals under uniaxial compression, Journal of Applied Mechanics-ASME, 2013, 通讯作者
(40) Surface energy controlled self-collapse of carbon nanotube bundle with large and reversible volumetric deformation, Journal of Applied Mechanics-ASME , 2013, 第 3 作者
(41) Stretch-induced softening of bending rigidity in graphene, applied physics letters, 2012, 通讯作者
(42) A theoretical analysis of the surface dependent binding, peeling and folding of graphene on single crystal copper, carbon, 2012, 通讯作者
(43) The nature of strength enhancement and weakening by pentagon–heptagon defects in graphene, Nature Materials, 2012, 第 4 作者
(44) Cellular uptake of elastic nanoparticles, Physical Review Letters, 2011, 第 2 作者
(45) Cell entry of one-dimensional nanomaterials occurs by tip recognition and rotation, Nature Nanotechnology, 2011, 第 1 作者

科研活动

   
科研项目
( 1 ) 纳米颗粒与细胞交互作用中的颗粒尺寸、形状、弹性性能效应研究, 主持, 国家级, 2003-01--2016-12
( 2 ) 国家优秀青年基金, 主持, 国家级, 2015-01--2017-12
( 3 ) 纳米颗粒形状效应影响其在粘蛋白网络结构中扩散的机制研究, 主持, 国家级, 2017-01--2020-12
( 4 ) 国家杰出青年基金, 主持, 国家级, 2022-01--2026-12
( 5 ) 多级次自组装体系中手性传递的机制研究, 主持, 国家级, 2021-01--2024-12
( 6 ) 原位加载下生理介质中粒子运动参数测量系统, 主持, 部委级, 2021-01--2022-12
( 7 ) 复杂载荷条件下生理屏障的结构演化和纳米药物 的输运研究, 主持, 部委级, 2021-01--2023-12

指导学生

已指导学生

李聪灵  硕士研究生  080102-固体力学  

殷其放  硕士研究生  085204-材料工程  

苏谦  硕士研究生  080102-固体力学  

王九令  博士研究生  080102-固体力学  

李华伟  硕士研究生  070205-凝聚态物理  

朱双  博士研究生  070205-凝聚态物理  

现指导学生

徐浩兰  博士研究生  0805J1-纳米科学与技术  

程锦皓  硕士研究生  0703J1-纳米科学与技术  

黄康  硕士研究生  085204-材料工程  

龚宇龙  博士研究生  0805J1-纳米科学与技术  

万铠玮  博士研究生  070304-物理化学  

徐赛  硕士研究生  0710J1-纳米科学与技术  

何建新  硕士研究生  0703J1-纳米科学与技术  

周童  硕士研究生  085600-材料与化工  

崔云晓  硕士研究生  0703J1-纳米科学与技术