生医材料,生物传感器,生物分子辨识机制,材料表面改性

2004-09--2010-01   Chemical and Materials Engineering   Ph. D
2002-09--2004-06   Biotechnology and Chemical Engineering   master
1998-09--2002-06   Biomedical Engineering    Bachelor

2022-12~现在, 中国科学院大学,材料科学与光电技术学院, 教授

2012-07~2022-12,中国科学院大学,材料科学与光电技术学院, 副教授

2011-09~2012-07,DeltaBio, INC., Taiwan, 研究员

2010-10~2011-01,Tokyo Tech’s Department of Metallurgy and Ceramics, Short-term visiting researcher

2010-04~2011-07,Biomedical Engineering, I-Shou University, Postdoctoral Research Fellow

2010-02~2011-01,Shanglin biotechnology company, Taiwan , R & D Consultant

纳米生物与仿生材料
高分子化学
可分解高分子材料实验
聚合物基复合材料
生物材料实验
生物可降解高分子材料
医用材料生物兼容性实验
生物科技仪器应用特论
高分子材料表面修饰及其生医应用
生物材料导论
IC半导体设备制程整合
文献阅读课
生物可降解高分子

（ 1 ） 一种无创皮下组织液提取装置的自适应调控系统, 发明专利, 2025, 第 2 作者, 专利号: ZL 2024 08139660

（ 2 ） 一种通过离子浓度定量体液分泌体积的方法及监测系统, 发明授权, 2025, 第 2 作者, 专利号: CN118830834B

（ 3 ） 一种通过离子浓度定量体液分泌体积的方法及监测系统, 发明专利, 2025, 第 2 作者, 专利号: ZL 2024 1 0866532.7

（ 4 ） 一种生物可分解高分子肠钉及其制备方法, 发明授权, 2024, 第 1 作者, 专利号: CN117919521B

（ 5 ） 一种生物可分解高分子肠钉及其制备方法, 发明专利, 2024, 第 1 作者, 专利号: ZL 2024 01080346

（ 6 ） 一种高抗垢性高准确率的粪便隐血传感器及其制备方法和应用, 发明专利, 2023, 第 2 作者, 专利号: ZL 2023 1 0728712.4

（ 7 ） 一种无创皮下组织液提取-检测装置和提取-检测方法, 发明授权, 2022, 第 1 作者, 专利号: CN114557694B

（ 8 ） 一种抗HCT干扰的葡萄糖传感器, 发明授权, 2022, 第 2 作者, 专利号: CN109270136B

（ 9 ） 一种用于生化分析的纸基电极检测平台及其制备方法, 发明授权, 2019, 第 1 作者, 专利号: CN105954331B

（ 10 ） 一种可连续旋转的光学扫描装置, 发明专利, 2018, 第 3 作者, 专利号: CN108169134A

（ 11 ） 一种可连续旋转的光学扫描装置, 发明专利, 2018, 第 3 作者, 专利号: CN107941698A

1.Invitation speaker and chair of Young Investigator’s Forum in BIT’s 4th International Congress of Antibodies - 2012 (ICA-2012), Beijing, China.

2. Invitation to be short-term visiting researcher in Tokyo Tech’s Department of Metallurgy and Ceramics Science (2010/11/15~2011/1/20)

3. Invitation to be interview in the Journals of Chinese edition of Electronics Letters

4. The Outstanding researcher Award in Nnational Central University, Taiwan, 2008

5. Jang-Zern Tsai, Zhen-Chia Liu, Ching-Jung Chen, Kai-Hung Hsueh, Yue-Ming Hsin, Wen-Yih Chen, “Characterization of Interdigitated Electrode Pairs as Biosensors for Human Serum Albumin”, The Asia-Pacific Biochemical Engineering Conference,Taipei, Taiwan, 2007 November.( The Outstanding researcher Award)

6. 劉仁材, 林勃伸, 陳文逸,“利用表面電漿共振儀檢測人類血清白蛋白”,生物醫學工程科技研討會暨國科會醫學工程學門成果發表會, 台中, 台灣, 2007 12月.(傑出研究獎)

   

（1） Integrated microfluidic colorimetric patch with auto-framing APP for multiplex temporal detection of ketone bodies in sweat, Lab on a Chip, 2025, 第 7 作者
（2） Metal-organic frameworks for electrochemical glucose sensors progress and challenges, Coordination Chemistry Reviews, 2025, 
（3） Fabrication and Evaluation of Screen-Printed Electrodes on Chitosan Films for Cardiac Patch Applications with In Vitro and In Vivo Evaluation, Polymers, 2025, 第 3 作者
（4） Flexible cellulose paper-based biosensor from inkjet printing for non-invasive glucose monitoring, POLYMER TESTING, 2024, 第 8 作者  通讯作者
（5） Calibration algorithms for continuous glucose monitoring systems based on interstitial fluid sensing, BIOSENSORS & BIOELECTRONICS, 2024, 第 2 作者  通讯作者
（6） Application of chitosan with different molecular weights in cartilage tissue engineering, CARBOHYDRATE POLYMERS, 2023, 第 6 作者  通讯作者
（7） Surface Plasmon Resonance (SPR) Combined Technology: A Powerful Tool for Investigating Interface Phenomena, ADVANCED MATERIALS INTERFACES, 2023, 第 5 作者  通讯作者
（8） Micro interstitial fluid extraction and detection device integrated with the optimal extraction conditions for noninvasive glucose monitoring, BIOSENSORS & BIOELECTRONICS, 2023, 第 5 作者  通讯作者
（9） Recent advances in disease diagnosis based on electrochemical-optical dual-mode detection method, TALANTA, 2023, 第 7 作者  通讯作者
（10） The Treatment of Keloid Scars via Modulating Heterogeneous Gelatin-Structured Composite Microneedles to Control Transdermal Dual-Drug Release, POLYMERS, 2022, 第 7 作者  通讯作者
（11） Analyzation of the binding mechanism and the isoelectric point of glycated albumin with self-assembled, aptamer-conjugated films by using surface plasmon resonance, Colloids and Surfaces B-Biointerfaces, 2022, 第 4 作者  通讯作者
（12） Review-Glucose Monitoring Sensors: History, Principle, and Challenges, JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 2022, 第 4 作者  通讯作者
（13） Investigation of the recognition interaction between glycated hemoglobin and its aptamer by using surface plasmon resonance, TALANTA, 2021, 第 5 作者  通讯作者
（14） A Facile Fabrication of Biodegradable and Biocompatible Cross-Linked Gelatin as Screen Printing Substrates, POLYMERS, 2020, 第 6 作者
（15） Non-Invasive Blood Glucose Monitoring Technology: A Review, SENSORS (BASEL, SWITZERLAND), 2020, 第 4 作者  通讯作者
（16） Peptide-based antifouling aptasensor for cardiac troponin I detection by surface plasmon resonance applied in medium sized Myocardial Infarction, Annals of Biomedical Science and Engineering 4(2020), 001-008., 2020, 第 5 作者  通讯作者
（17） 一种低成本的表面等离子体共振检测系统, Low Cost Surface Plasmon Resonance Sensor System, 仪表技术与传感器, 2019, 第 3 作者
（18） An anti-HCT-interference glucose sensor based on a fiber paper-based screen-printed carbon electrode, SENSORS AND ACTUATORS B-CHEMICAL, 2019, 第 5 作者  通讯作者
（19） High-sensitivity glycated hemoglobin (HbA1c) aptasensor in rapid-prototyping surface plasmon resonance, SENSORS AND ACTUATORS B-CHEMICAL, 2019, 第 5 作者  通讯作者
（20） Angle-Scanning Surface Plasmon Resonance System with 3D Printed Components for Biorecognition Investigation, ADVANCES IN CONDENSED MATTER PHYSICS, 2018, 第 4 作者  通讯作者
（21） Preparation and evaluation of chitosan biocompatible electronic skin, COMPUTERS IN INDUSTRY, 2018, 第 7 作者  通讯作者
（22） A Flexible Interdigital Electrode Used in Skin Penetration Promotion and Evaluation with Electroporation and Reverse Iontophoresis Synergistically, SENSORS, 2018, 第 7 作者
（23） Development of carbon−graphene-based aptamer biosensor for EN2 protein detection, ANALYTICAL BIOCHEMISTRY, 2017, 第 2 作者
（24） 一步水热法合成超低电荷转移阻抗的碳材料及其葡萄糖检测性能研究, Ultra-low charge transfer resistance carbons by onepot hydrothermal method for glucose sensing, SCIENCE CHINA Materials, 2017, 第 2 作者  通讯作者
（25） In Situ Reductive Synthesis of Structural Supported Gold Nanorods in Porous Silicon Particles for Multifunctional Nanovectors, ACS APPLIED MATERIALS & INTERFACES, 2016, 第 2 作者
（26） Analytical performance of paper electro-biosensor detection platform for point-of-care diagnosis, CELLULOSE, 2016, 第 3 作者  通讯作者
（27） Paper-based electrochemical biosensor detection platform, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2016, 第 1 作者
（28） Screen-printed carbon electrode-based electrochemical immunosensor for rapid detection of microalbuminuria, BIOSENSORS & BIOELECTRONICS, 2016, 第 6 作者  通讯作者
（29） Porous carbon paste electrode for biomarker detection, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2016, 第 3 作者  通讯作者
（30） Detecting human serum albumin using screen-printed carbon electrode by cyclic voltammetry, JOURNAL OF MICROBIOLOGY, IMMUNOLOGY AND INFECTION, 2015, 第 2 作者
（31） Capacitance sensor for detecting Escherichia Coli in urinary tract infection diagnosis, JOURNAL OF MICROBIOLOGY, IMMUNOLOGY AND INFECTION, 2015, 第 3 作者
（32） Impedimetric method for measuring ultra-low E. coli concentrations in human urine, BIOSENSORS AND BIOELECTRONICS, 2015, 第 3 作者  通讯作者
（33） Impedance sensor for rapid enumeration of E. coli in milk samples, ELECTROCHIMICA ACTA, 2015, 第 1 作者
（34） Resonant efficiency improvement design of piezoelectric biosensor for bacteria gravimetric sensing, BIO-MEDICAL MATERIALS AND ENGINEERING, 2014, 第 4 作者
（35） Concept for E. coli Detection Using Interdigitated Microelectrode Impedance Sensor, 2013 35TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2013, 第 2 作者  通讯作者
（36） Development of a portable impedance detection system for monitoring the growth of mouse L929 cells, JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS, 2012, 第 2 作者
（37） Surface plasmon resonance biosensor with high anti-fouling ability for the detection of cardiac marker troponin T, ANALYTICA CHIMICA ACTA, 2011, 第 1 作者  通讯作者
（38） A Guided Mode Resonance Aptasensor for Thrombin Detection, SENSORS, 2011, 第 3 作者
（39） Surface plasmon resonance biosensor for microalbumin detection, JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS, 2011, 第 1 作者
（40） Capacitance Sensor System for Oligonucleotide Hybridization Detection, SENSORS AND MATERIALS, 2011, 第 4 作者
（41） A new PZT piezoelectric sensor for gravimetric applications using the resonance-frequency detection, SENSORS AND ACTUATORS B-CHEMICAL, 2009, 第 1 作者
（42） The investigation of recognition interaction between phenylboronate monolayer and glycated hemoglobin using surface plasmon resonance, ANALYTICAL BIOCHEMISTRY, 2008, 第 1 作者
（43） The hydrophobic interactions of the ion-exchanger resin ligands with proteins at high salt concentrations by adsorption isotherms and isothermal titration calorimetry, SEPARATION AND PURIFICATION TECHNOLOGY, 2007, 

已指导学生

陶常冰  硕士研究生  085204-材料工程  

胡博韬  硕士研究生  080502-材料学  

冯吉勇  硕士研究生  085204-材料工程  

唐柳  硕士研究生  085204-材料工程  

荆岩珍  硕士研究生  085204-材料工程  

现指导学生

张润杰  硕士研究生  085600-材料与化工  

张丙焕  硕士研究生  080502-材料学  

辛佳霖  硕士研究生  085600-材料与化工  

刘禹宸  硕士研究生  085400-电子信息  

王丽媛  硕士研究生  085600-材料与化工