基本信息
侯宏伟  男  博导  中国科学院水生生物研究所
电子邮件: houhw@ihb.ac.cn
通信地址: 湖北省武昌东湖南路7号,中国科学院水生生物研究所
邮政编码: 430072

研究领域

遗传学;水生生物学;植物学;生态学

研究兴趣

1、 环境因子对植物表型的调控和机制研究:“异形叶”指基因型相同的植物由于环境差异,叶形出现显著差异的现象,这种现象为研究环境对表型的调控作用提供了一个理想的研究模型。通过筛选,我们发现原产于热带和亚热带地区的一种水族观赏植物 – 爵床科(Acanthaceae)的异叶水蓑衣(Hygrophila difformis)的叶形在陆生和水生条件下差异显著,是典型的异形叶,对环境敏感、易于扩繁、组织培养和遗传转化简便,并以此植物为主要研究材料,研究环境因子、基因和植物激素等对异形叶形态的调控关系,目前已初步建立了环境因子调控异形叶形态的基因调控网络和主要途径。

2、 浮萍研究及应用:浮萍(Duckweed)属天南星科(Araceae)浮萍亚科(Lemnoideae)的水生高等植物,广布于各种淡水生境,包括紫萍属(Spirodela)、斑萍属(Landoltia)、青萍属(Lemna)、扁无根萍属 (Wolffiella)、芜萍属(Wolffia),36个种。浮萍具有个体小、结构简单、繁殖快等特点,适宜于工厂化生产,使其在研究植物形态建成、发育和进化,以及生物技术应用等方面有极大潜力。我们采(收)集了包括全部芜萍11个种的浮萍18个种,从种质保藏、无菌培养和遗传转化方法建立入手,结合形态解剖、比较基因组学等研究方法研究浮萍器官退化的可能机制,研究PHR1(Phosphate Starvation Response1)-miR399-lncRNA在浮萍低磷胁迫应答中的功能;我们还建立了浮萍生物反应器,用于表达鱼类抗病物质;此外,还筛选了适于监测和富集重金属的浮萍品系,并对Nramps(金属离子转运蛋白)、PCS(植物络合素)、GSH(谷胱甘肽)等重金属转运相关蛋白编码基因进行了克隆和功能研究。  

3、水生植物生态学研究:水生植物是湖泊、湿地等淡水生态系统重要的初级生产者,是水生生物群落多样性的基础,也是维持生态系统运转的关键类群,其多样性、环境适应和种群动态同样具有重要意义。我们以高原和长江流域的重要湖泊为对象,采用综合营养状态指数法对湖泊的营养水平现状进行评估;由于水环境中N、P等营养化水平会影响不同繁殖类型水生植物的繁殖方式,从而改变物种遗传格局,我们选择代表性的水生植物,如:菱(Trapa bispinosa)(有性生殖)、苦草(Vallisneria natans)(有性生殖和无性生殖混合)、金鱼藻(Ceratophyllum demersum)(无性生殖)等,用AFLP分子标记、甲基敏感多态性分析(MSAP)和微卫星标记(Microsatellite)等方法揭示不同的时空因素对物种、种群和个体水平的多样性和遗传格局的影响,揭示水生植物的分布、遗传多样性演变的规律及其在淡水生态系统中的功能。  

4、水生蔬菜、种养结合和循环农业研究及应用:通过多种栽培方式和组织培养等方法,研究水芹(Oenanthe javanica)、豆瓣菜(Nasturtium officinale)等水生蔬菜在水、温度等逆境胁迫下的生理变化和基因表达,鉴定重要性状基因,筛选优良种质。我们还与武汉市农科院蔬菜所、安徽省凤台县、武汉市江夏区等合作,建立种养结合和循环农业模式,研究水生蔬菜在浮床等生产方式下对畜禽粪污的消纳和应用等。 


招生专业
071007-遗传学
071004-水生生物学
071012-生态学
招生方向
植物生理学;遗传学
分子生物学;发育生物学
水生生物学

教育背景

1999-09--2004-06 北京大学 博士学位
1985-09--1989-06 河南师范大学 本科/理学学士
学历
博士研究生

学位
博士

近期发表论文

1.杨晶晶, 赵旭耀, 李高洁, 胡诗琦, 陈艳, 孙作亮,侯宏伟.浮萍的研究及应用进展,科学通报,2021.66(9):1026-1045.

2.李高洁,胡诗琦,杨晶晶,侯宏伟. 植物异形叶研究进展,植物生理学报,2020. 56 (10):2067–2078.

3.吴志刚, 熊文, 侯宏伟*. 长江流域水生植物多样性格局与保护. 水生生物学报 2018.43: 1000-3207.

4.Sun, ZL; Zhao, XY; Li, GJ; Yang, JJ; Chen, Y; Xia, ML; Hwang, I; Hou, HW*,Metabolic flexibility during a trophic transition reveals the phenotypic plasticity of greater duckweed (Spirodela polyrhiza 7498), New Phytologiest, 2023, Accepted(IF5y=10.768)

5.Li, GJ; Yang, JJ; Chen, YM; Zhao, XY; Chen Y; Kimura S; Hu SQ; Hou, HW*, SHOOT MERISTEMLESS participates in the heterophylly of Hygrophila difformis (Acanthaceae). Plant Physiol, 2022, 190: 1777-1791 (IF5y=9.115)

6.Li, GJ; Chen, Y; Zhao, XY; Yang, JJ*; Wang XY; Li XZ; Hu SQ; Hou, HW*, Genome-wide analysis of the Growth-regulating factor (GRF) family in aquatic plants and their roles in the ABA-induced turion formation of Spirodela polyrhiza. Int J Mol Sci, 2022, 23:10485(IF5y=6.628)

7.Zhao, XY; Yang, JJ; Li, XZ; Li GJ; Sun, ZL; Chen Y; Chen YM; Xia ML; Li YX; Yao LG; Hou, HW*, Identification and expression analysis of GARP superfamily genes in response to nitrogen and phosphorus stress in Spirodela polyrhiza. BMC Plant Biol, 2022, 22: 308(IF5y=5.761)

8.Sun, ZL; Guo WJ; Zhao, XY; Chen Y; Yang, JJ; Xu SQ; Hou, HW*, Sulfur limitation boosts more starch accumulation than nitrogen or phosphorus limitation in duckweed (Spirodela polyrhiza). Ind Crop Prod, 2022, 185:115098(IF5y=6.508)

9.Yang, JJ; Li, GJ; Xia, ML; Chen, YM; Chen, Y; Kumar, S; Sun, ZL; Li, XZ; Zhao, XY*; Hou, HW*,  Combined effects of temperature and nutrients on the toxicity of cadmium in duckweed (Lemna aequinoctialis). J Hazard Mater, 2022, 43: 128646 (IF5y=14.2)

10.Yang, JJ; Zhao, XY; Chen, Y; Li, GJ; Li, XZ; Xia, ML; Sun, ZL;  Chen, YM; Li, YX; Yao, LG; Hou, HW*, Identification, structural, and expression analyses of SPX genes in giant duckweed (Spirodela polyrhiza) reveals its role in response to low phosphorus and nitrogen Stresses. Cells, 2022, 11: 1167 (IF5y=6.60)

11.Chen, Y; Li, GJ; Yang, JJ; Zhao, XY; Sun, ZL; Hou, HW*, Role of nramp transporter genes of Spirodela polyrhiza in cadmium accumulation. Ecotox Environ Safe, 2021, 227: 112907(IF5y=6.393)

12.Chen, Y; Zhao, XY; Li, GJ; Kumar, S; Sun, ZL; Li, YX; Guo, WJ; Yang, JJ*; Hou, HW*, Genome-wide identification of the Nramp gene family in Spirodela polyrhiza and expression analysis under cadmium stress. Int J Mol Sci, 2021, 22: 6414(IF5y=6.132)

13.Yang, JJ; Zhao, XY; Li, GJ; Hu, SQ; Hou, HW*, Frond architecture of the rootless duckweed Wolffia globosa. BMC Plant Biol, 2021, 21: 387(IF5y=4.96)

14. Kumar, S; Li, GJ; Huang, XF; Ji, Q; Zhou, K; Hou, HW; Ke, WD*; Yang, JJ*, Phenotypic, nutritional, and antioxidant characterization of blanched Oenanthe javanica for preferable cultivar. Front Plant Sci, 2021, 12: 639639(IF5y=6.612)

15.Kumar, S; Li, GJ; Yang, JJ; Huang, XF; Ji, Q; Liu, ZW; Ke, WD*; Hou, HW*, Effect of salt stress on growth, physiological parameters, and ionic concentration of water dropwort (Oenanthe javanica) cultivars. Front Plant Sci, 2021, 12: 660409(IF5y=6.612)

16.Zhao, XY; Li, GJ; Sun, ZL; Chen, Y; Guo, WJ; Li, YX; Chen, YM; Yang, JJ*; Hou, HW*, Identification, structure analysis, and transcript profiling of phosphate transporters under Pi deficiency in duckweeds. Int J Biol Macromol, 2021, 188 : 595-608(IF5y=6.737)

17.Zhao, XY; Yang, JJ; Li, GJ; Sun, ZL; Hu SQ; Chen Y; Guo WJ; Hou HW*, Genome-wide identification and comparative analysis of the WRKY gene family in aquatic plants and their response to abiotic stresses in giant duckweed (Spirodela polyrhiza). Genomics, 2021, 113: 1761-1777(IF5y=4.939)

18.Li, GJ; Hu SQ; Zhao, XY; Kumar S; Li YX; Yang JJ*; Hou HW*,  Mechanisms of the morphological plasticity induced by phytohormones and the environment in plants. Int J Mol Sci, 2021, 22: 765(IF5y=6.132)

19.Kumar, S; Li, GJ; Yang JJ; Huang, XF; Ji Q; Zhou, K; Khan,  S; Ke, WD*; Hou HW*, Investigation of an antioxidative system for salinity tolerance in Oenanthe javanica.Antioxidants, 2020, 9, 940 (IF5y=6.313)

20.Sun, ZL;  Guo, WJ;  Yang, JJ;  Zhao, XY;  Chen, Y;  Yao, LG; Hou HW*. Enhanced biomass production and pollutant removal by duckweed in mixotrophic conditions. Bioresour Technol. 2020, 317:124029 (IF5y=9.237)

21.Heenatigala, PPM;  Sun, ZL;  Yang, JJ;  Zhao, XY;  Hou, HW*, Expression of LamB vaccine antigen in Wolffia globosa (Duckweed) against fish vibriosis. Front Immunol, 2020, 11: 1857 (IF5y=7.561) 

22.Li, GJ #;  Hu, SQ #;  Yang, JJ;  Zhao, XY;  Schultz, E;  Kimura, S;  Hou, HW*, Establishment of an Agrobacterium mediated transformation protocol for the detection of cytokinin in the heterophyllous plant Hygrophila difformis (Acanthaceae), Plant Cell Rep, 2020, 39:737-750 (IF5y=4.463)

23.Wu, ZG; Xu, X; Zhang, J; Wiegleb, G; Hou, HW*, Influence of environmental factors on the genetic variation of the aquatic macrophyte Ranunculus subrigidus on the Qinghai-Tibetan Plateau. BMC Evol Biol, 2019, 19: 228  (IF5y=3.260)

24.Yang, JJ; Li, GJ; Hu, SQ; Bishopp, A; Heenatigala, PPM; Kumar, S; Duan, PF; Yao, LG; Hou HW*, A protocol for efficient callus induction and stable transformation of Spirodela polyrhiza (L.) Schleiden using Agrobacterium tumefaciens. Aquat Bot, 2018, 151: 80-86 (IF5y=2.417)

25.Heenatigala, PPM;  Yang, JJ;  Bishopp, A;  Sun, ZL; Li, GJ; Kumar, S;  Hu, SQ;  Wu, ZG;  Lin W;  Yao, LG;  Duan, PF;  Hou, HW*, Development of efficient protocols for stable and transient gene transformation for Wolffia globosa using Agrobacterium. Front Chem, 2018, 6: 227 (IF5y=5.385) 

26.Mariyamma, NP; Hou, HW; Carland, FM; Nelson, T; Schultz, EA*, Localization of Arabidopsis FORKED1 to a RABA positive compartment suggests a role in secretion. J Exp Bot, 2017, 68:3375-3390  (IF5y=7.860) 

27.Li, GJ; Hu, SQ; Hou, HW; Kimura, S*, Heterophylly: phenotypic plasticity of leaf shape in aquatic and amphibious. Plants, 2019, 8 420 (IF5y=3.396)

28.Khan, S; Liu, Y; Siddique, R; Nabi, G; Xue, M*; Hou, HW*, Impact of chronically alternating light-dark cycles on circadian clock mediated expression of cancer (glioma)-related genes in the brain. Int J Biol Sci, 2019, 15: 1816-1834  (IF5y=6.479)

29.Mariyamma, N; Clarke, K; Yu, H; Hou, HW; Wilton, E; Dyk, J; Schultz, E*, Members of the Arabidopsis FORKED1-LIKE gene family act to localize PIN1 in developing veins. J Exp Bot, 2018, 69: 4773-4790 (IF5y=7.860)

30.Khan, S; Nabi, G; Yao, L*; Siddique, R; Sajjad, W; Kumar, S; Duan, P; Hou, HW*, Health risks associated with genetic alterations in internal clock system by external factors. Int J Biol Sci, 2018, 14: 791-798  (IF5y=6.479)

31.Khan, S; Duan, P; Yao, L*; Hou, HW*, Shiftwork-mediated disruptions of circadian rhythms and sleep homeostasis cause serious health problems. Int J Genomics. 2018, 2018: 8576890 (IF5y=2.557) 

32.Li, GJ; Hu, SQ; Yang, JJ; Schultz E; Clarke K; Hou HW*, Water-Wisteria as an ideal plant for heterophylly study in higher aquatic plants. Plant Cell Reports, 2017. 36: 1225-1236 (IF5y=4.463) 

33.Hu, SQ; Li, GJ; Yang, JJ; Hou, HW*, Aquatic plant genomics: advances, applications, and prospects. Int J Genomics, 2017, 2017: 6347874 (IF5y=2.557)

34.Wu, Z; Wu, J; Wang, Y; Hou HW*, Development of EST-derived microsatellite markers in the aquatic macrophyte Ranunculus bungei (Ranunculaceae). Applications in Plant Sciences, 2017, 5: 1700022 (IF5y=1.929)

35.Mariyamma, N; Hou, HW; Carland, F; Nelson, T; Schultz, E*, Localization of Arabidopsis FORKED1 to a RABA positive compartment suggests a role in secretion. J Exp Bot, 2017, 68: 3375-3390  (IF5y=7.860)

36. Khan, S; Ullah, M; Siddique, R; Nabi, G; Manan, S; Yousaf, M; Hou, HW*, Role of recombinant DNA technology to improve life. Int J Genomics, 2016, 2016: 2405954 (IF5y=2.557)

37. Shen, S; Hou, HW; Ding, C; Bing, D; Lu, Z*, Protein content correlates with starch morphology, composition and physicochemical properties in field peas. Can J Plant Sci, 2016, 96: 404–412 (IF5y=1.018)

38.Hou, HW*; Atlihan, N; Lu, ZX*, New biotechnology enhances the application of cisgenesis in plant breeding. Front Plant Sci. 2014, 5: 389  (IF5y=6.612)

39.Yoon, H#; Hossain, M#; Held, M; Hou, HW; Kehl, M;Tromas, A; Sato, S;Tabata, T; Andersen, S; Stougaard, J; Ross, L; Szczyglowski, K*, Lotus japonicus SUNERGOS1 encodes apredicted subunit A of a DNA topoisomerase VI and is required for nodule differentiationand accommodation of rhizobial infection. Plant J, 2014, 78: 811-821 (IF5y=7.666)

40.Hou, HW; Zhang, Z*; Zhao, W; Hou, J, Generating DNA sequences encoding tandem peptide repeats suitable for expression and immunological application. World J Microbiol Biotechnol, 2012, 28: 2175-80 (IF5y=3.580)

41.Garrett, J#; Meents, M; Blackshaw, M; Blackshaw, L; Hou, HW; Styranko, D; Kohalmi, S; Schultz, E*, A novel, semi-dominant allele of MONOPTEROS provides insight into leaf initiation and vein pattern formation. Planta, 2012, 236: 297-312 (IF5y=4.316)

42.Hou, HW; Erickson, J; Meservy, J; Schultz, E*, FORKED1 encodes a PH domain proteinthat is required for PIN1 canalization in developing leaf veins. Plant J, 2010, 63: 960–973 (IF5y=7.666)

43.Held, M#; Hou, H#; Miri, M#; Huynh, C; Ross, L; Hossain, S; Sato, S; Tabata, S; Perry, J; Wang, T; Szczyglowski, K*, Lotus japonicus cytokinin receptors work partially redundantly to mediate nodule formation. Plant Cell, 2014, 26: 678-694 (IF5y=12.061)

44.Hou, HW; Zhou, Y; He, X; Mwange, K; Li, W; Cui, K*, The ABP1 expression regulated by IAA and ABA is associated with the cambial activity periodicity in Eucommia ulmoides. J Exp Bot, 2006, 57: 3857-3867  (IF5y=7.860)

45.Mwange, K#; Hou, HW#;Wang, Y; He, X; Cui, K*, Opposite patterns in the annual distribution and time course of endogenous abscisic acid and indole-3-acetic acid in relation to the periodicity of cambial activity in Eucommia ulmoides Oliv. J Exp Bot, 2005, 56: 1017-1028 (IF5y=7.860)

46.Mwange, K; Hou, HW; Cui, K*, Relationship between endogenous indole-3-acetic acid and abscisic acid changes and bark recovery in Eucommia ulmoides after girdling. J Exp Bot, 2003, 54: 1899-1907  (IF5y=7.860)


工作经历

   

专利与奖励

   
专利成果
[1] 侯宏伟, 孙作亮, 杨晶晶, 支承钧, 王杰. 一种提高紫萍生物量积累和对氮、磷、COD去除效率的方法. CN: CN112056198A, 2020-12-11.
[2] 杨晶晶, 侯宏伟. 一种农杆菌介导的紫萍稳定转化体系建立的方法. CN: CN106011169A, 2016-10-12.

科研活动