发表论文
[1] Huabin Tian, Kuai Yu, Liang He, Hongtao Xu, Chuanhui Han, Xiaolin Zhang, Xinlu Wang, Xuyuan Zhang, Liguo Zhang, Guangxia Gao, Hongyu Deng. RNF213 modulates γ-herpesvirus infection and reactivation via targeting the viral Replication and Transcription Activator. Proc Natl Acad Sci U S A[J]. 2023, 120(12): e2218825120-, [2] Dexin Mao, Feixiang Yan, Xiaolin Zhang, Guangxia Gao. TMEM106A inhibits enveloped virus release from cell surface. ISCIENCE[J]. 2022, 25(2): [3] Fu, Shaozu, Phan, An Thanh, Mao, Dexin, Wang, Xinlu, Gao, Guangxia, Goff, Stephen P, Zhu, Yiping. HIV-1 exploits the Fanconi anemia pathway for viral DNA integration. CELL REPORTS[J]. 2022, 39(8): http://dx.doi.org/10.1016/j.celrep.2022.110840.[4] Yan, Feixiang, Yang, Wei, Wang, Xinlu, Gao, Guangxia. TMEM45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication. JOURNAL OF VIROLOGY[J]. 2022, 96(17): http://dx.doi.org/10.1128/jvi.00919-22.[5] Luo, Xiu, Wang, Xinlu, Gao, Yina, Zhu, Jingpeng, Liu, Songqing, Gao, Guangxia, Gao, Pu. Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein. CELL REPORTS[J]. 2020, 30(1): 46-+, http://dx.doi.org/10.1016/j.celrep.2019.11.116.[6] Liu, Lixin, Liu, Zhijia, Chen, Haolin, Liu, Hong, Gao, Qiang, Cong, Feng, Gao, Guangxia, Chen, Yongming. Subunit Nanovaccine with Potent Cellular and Mucosal Immunity for COVID-19. ACS APPLIED BIO MATERIALS[J]. 2020, 3(9): 5633-5638, http://dx.doi.org/10.1021/acsabm.0c00668.[7] Yong Wang, Qi Zhan, Xinlu Wang, Peipei Li, Songqing Liu, Guangxia Gao, Pu Gao. Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://dx.doi.org/10.1038/s41467-020-16587-w.[8] Xinlu Wang, Yifang Xuan, Yuling Han, Xiang Ding, Kai Ye, Fuquan Yang, Pu Gao, Stephen P Goff, Guangxia Gao. Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed −1 Ribosomal Frameshifting. CELL[J]. 2019, 176(3): 625-635.e14, [9] Luo, Xinlong, Yang, Wei, Gao, Guangxia. SUN1 Regulates HIV-1 Nuclear Import in a Manner Dependent on the Interaction between the Viral Capsid and Cellular Cyclophilin A. JOURNAL OF VIROLOGY[J]. 2018, 92(13): https://www.webofscience.com/wos/woscc/full-record/WOS:000435100400011.[10] Xia, Pengyan, Wang, Shuo, Xiong, Zhen, Zhu, Xiaoxiao, Ye, Buqing, Du, Ying, Meng, Shu, Qu, Yuan, Liu, Jing, Gao, Guangxia, Tian, Yong, Fan, Zusen. The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity. NATURE IMMUNOLOGY[J]. 2018, 19(2): 141-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000423435200014.[11] Zhang, Xiaolin, Yang, Wei, Wang, Xinlu, Zhang, Xuyuan, Tian, Huabin, Deng, Hongyu, Zhang, Liguo, Gao, Guangxia. Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-beta activation. PROTEIN & CELL[J]. 2018, 9(9): 799-807, https://www.webofscience.com/wos/woscc/full-record/WOS:000442649400006.[12] Tang, Qiannan, Wang, Xinlu, Gao, Guangxia. The Short Form of the Zinc Finger Antiviral Protein Inhibits Influenza A Virus Protein Expression and Is Antagonized by the Virus-Encoded NS1. JOURNAL OF VIROLOGY[J]. 2017, 91(2): [13] Chen, Shaohong, Gao, Guangxia. MicroRNAs recruit eIF4E2 to repress translation of target mRNAs. PROTEIN & CELL[J]. 2017, 8(10): 750-761, http://lib.cqvip.com/Qikan/Article/Detail?id=673698842.[14] Zheng, Xiaojiao, Wang, Xinlu, Tu, Fan, Wang, Qin, Fan, Zusen, Gao, Guangxia. TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein. JOURNAL OF VIROLOGY[J]. 2017, 91(9): https://www.webofscience.com/wos/woscc/full-record/WOS:000399474400007.[15] Wang, Qin, Zhang, Xiaolin, Han, Yuling, Wang, Xinlu, Gao, Guangxia. M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner. SCIENTIFIC REPORTS[J]. 2016, 6: http://www.corc.org.cn/handle/1471x/2375680.[16] Wang, Xinlu, Li, Melody M H, Zhao, Jing, Li, Shenglan, MacDonald, Margaret R, Rice, Charles M, Gao, Xiang, Gao, Guangxia. Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance. JOURNAL OF VIROLOGY[J]. 2016, 90(22): 10247-10258, https://www.webofscience.com/wos/woscc/full-record/WOS:000388468800018.[17] Pingping Zhu, Yanying Wang, Jiayi Wu, Guanling Huang, Benyu Liu, Buqing Ye, Ying Du, Guangxia Gao, Yong Tian, Lei He, Zusen Fan. LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells. NATURE COMMUNICATIONS[J]. 2016, 7(1): https://doaj.org/article/a14e02b6cfc44b4dbfedd36546c25516.[18] Xia, Pengyan, Wang, Shuo, Gao, Pu, Gao, Guangxia, Fan, Zusen. DNA sensor cGAS-mediated immune recognition. PROTEIN & CELL[J]. 2016, 7(11): 777-791, https://doaj.org/article/08e64bcfa6514b819f3e4423a0825201.[19] Tao, Xianzun, Gao, Guangxia. Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs. MOLECULAR AND CELLULAR BIOLOGY[J]. 2015, 35(22): 3921-3932, http://dx.doi.org/10.1128/MCB.00845-15.[20] Mu, Xin, Fu, Yajing, Zhu, Yiping, Wang, Xinlu, Xuan, Yifang, Shang, Hong, Goff, Stephen P, Gao, Guangxia. HIV-1 Exploits the Host Factor RuvB-like 2 to Balance Viral Protein Expression. CELL HOST & MICROBE[J]. 2015, 18(2): 233-242, http://dx.doi.org/10.1016/j.chom.2015.06.018.[21] Xuan, Yifang, Gong, Danyang, Qi, Jing, Han, Chuanhui, Deng, Hongyu, Gao, Guangxia. ZAP Inhibits Murine Gammaherpesvirus 68 ORF64 Expression and Is Antagonized by RTA. JOURNAL OF VIROLOGY[J]. 2013, 87(5): 2735-2743, http://www.irgrid.ac.cn/handle/1471x/756633.[22] Mu, Xin, Li, Wei, Wang, Xinlu, Gao, Guangxia. YB-1 stabilizes HIV-1 genomic RNA and enhances viral production. PROTEIN & CELL[J]. 2013, 4(8): 591-597, http://www.irgrid.ac.cn/handle/1471x/756661.[23] Xu, Jiwei, Peng, Wei, Sun, Yao, Wang, Xiangxi, Xu, Yihui, Li, Xuemei, Gao, Guangxia, Rao, Zihe. Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase. NUCLEIC ACIDS RESEARCH[J]. 2012, 40(14): 6957-6965, http://dx.doi.org/10.1093/nar/gks359.[24] Li, Wei, Wang, Xinlu, Gao, Guangxia. Expression of YB-1 enhances production of murine leukemia virus vectors by stabilizing genomic viral RNA. PROTEIN & CELL[J]. 2012, 3(12): 943-949, http://www.irgrid.ac.cn/handle/1471x/756793.[25] Xuan, Yifang, Liu, Ling, Shen, Sheng, Deng, Hongyu, Gao, Guangxia. Zinc Finger Antiviral Protein Inhibits Murine Gammaherpesvirus 68 M2 Expression and Regulates Viral Latency in Cultured Cells. JOURNAL OF VIROLOGY[J]. 2012, 86(22): 12431-12434, http://www.irgrid.ac.cn/handle/1471x/756987.[26] Wang, Xinlu, Tu, Fan, Zhu, Yiping, Gao, Guangxia. Zinc-Finger Antiviral Protein Inhibits XMRV Infection. PLOS ONE[J]. 2012, 7(6): http://www.irgrid.ac.cn/handle/1471x/756988.[27] Sun, Lin, Lv, Fengxiang, Guo, Xuemin, Gao, Guangxia. Glycogen Synthase Kinase 3 beta (GSK3 beta) Modulates Antiviral Activity of Zinc-finger Antiviral Protein (ZAP). JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2012, 287(27): 22882-22888, http://dx.doi.org/10.1074/jbc.M111.306373.[28] Wang ZhongFeng, Wang XinLu, Gao GuangXia. PR65A Regulates The Activity of The Zinc-finger Antiviral Protein. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2012, 39(5): 431-437, http://www.irgrid.ac.cn/handle/1471x/756892.[29] Chen, Shoudeng, Xu, Yihui, Zhang, Kuo, Wang, Xinlu, Sun, Jian, Gao, Guangxia, Liu, Yingfang. Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA. NATURE STRUCTURAL & MOLECULAR BIOLOGY[J]. 2012, 19(4): 430-435, http://dx.doi.org/10.1038/nsmb.2243.[30] Zhu, Yiping, Wang, Xinlu, Goff, Stephen P, Gao, Guangxia. Translational repression precedes and is required for ZAP-mediated mRNA decay. EMBO JOURNAL[J]. 2012, 31(21): 4236-4246, http://dx.doi.org/10.1038/emboj.2012.271.[31] Da, Qi, Yang, Xuanming, Xu, Youli, Gao, Guangxia, Cheng, Genhong, Tang, Hong. TANK-Binding Kinase 1 Attenuates PTAP-Dependent Retroviral Budding through Targeting Endosomal Sorting Complex Required for Transport-I. JOURNAL OF IMMUNOLOGY[J]. 2011, 186(5): 3023-3030, http://www.irgrid.ac.cn/handle/1471x/757441.[32] Zhu, Yiping, Chen, Guifang, Lv, Fengxiang, Wang, Xinlu, Ji, Xin, Xu, Yihui, Sun, Jing, Wu, Li, Zheng, YongTang, Gao, Guangxia. Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2011, 108(38): 15834-15839, http://dx.doi.org/10.1073/pnas.1101676108.[33] Ding, Jiwei, Su, Lishan, Gao, Guangxia. Hrs inhibits citron kinase-mediated HIV-1 budding via its FYVE domain. PROTEIN & CELL[J]. 2011, 2(6): 470-476, http://dx.doi.org/10.1007/s13238-011-1053-y.[34] Ye, Peiying, Liu, Shufeng, Zhu, Yiping, Chen, Guifang, Gao, Guangxia. DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein. PROTEIN & CELL[J]. 2010, 1(10): 956-964, http://www.corc.org.cn/handle/1471x/2407965.[35] Mai, Yun, Gao, Guangxia. Expression of IMP1 Enhances Production of Murine Leukemia Virus Vector by Facilitating Viral Genomic RNA Packaging. PLOS ONE[J]. 2010, 5(12): http://www.irgrid.ac.cn/handle/1471x/757121.[36] Huang, Zhi, Wang, Xinlu, Gao, Guangxia. Analyses of SELEX-derived ZAP-binding RNA aptamers suggest that the binding specificity is determined by both structure and sequence of the RNA. PROTEIN & CELL[J]. 2010, 1(8): 752-759, https://www.webofscience.com/wos/woscc/full-record/WOS:000208511300009.[37] Wang, Xinlu, Lv, Fengxiang, Gao, Guangxia. Mutagenesis analysis of the zinc-finger antiviral protein. RETROVIROLOGY[J]. 2010, 7(1): http://dx.doi.org/10.1186/1742-4690-7-19.[38] Wolf, Daniel, Gao, Guangxia, Guo, Xuemin, Bick, Matthew J, Carroll, JohnWilliam N, MacDonald, Margaret R, Goff, Stephen P. Retroviral restriction factors: new mechanisms of innate immunity. RETROVIROLOGY[J]. 2009, 6(Suppl 2): I1-I1, http://www.irgrid.ac.cn/handle/1471x/758014.[39] Kuang, YiQun, Tang, Xia, Liu, FengLiang, Jiang, XueLong, Zhang, YaPing, Gao, Guangxia, Zheng, YongTang. Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection. RETROVIROLOGY[J]. 2009, 6(1): http://159.226.149.42:8080:8088/handle/152453/4669.[40] Xu, Jing, Liu, Shufeng, Xu, Yihui, Tien, Po, Gao, Guangxia. Identification of the nonstructural protein 4B of hepatitis C virus as a factor that inhibits the antiviral activity of interferon-alpha. VIRUS RESEARCH[J]. 2009, 141(1): 55-62, http://dx.doi.org/10.1016/j.virusres.2009.01.001.[41] Zhu, Yiping, Gao, Guangxia. ZAP-mediated mRNA degradation. RNA BIOLOGY. 2008, 5(2): 65-67, http://www.irgrid.ac.cn/handle/1471x/757767.[42] Chen, Guifang, Guo, Xuemin, Lv, Fengxiang, Xu, Yihui, Gao, Guangxia. p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2008, 105(11): 4352-4357, http://www.irgrid.ac.cn/handle/1471x/757710.[43] Guo, Xuemin, Ma, Jing, Sun, Jing, Gao, Guangxia. The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2007, 104(1): 151-156, https://www.webofscience.com/wos/woscc/full-record/WOS:000243456300029.[44] Li ZhiQiang, Liu LiXin, Lu FengXiang, Ma Jing, Gao GuangXia. Fusing ZAP to HIV RNA binding proteins to inhibit HIV. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2007, 34(1): 50-56, https://www.webofscience.com/wos/woscc/full-record/WOS:000243624800007.[45] Liu, LX, Chen, GF, Ji, X, Gao, GX. ZAP is a CRM1-dependent nucleocytoplasmic shuttling protein. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2004, 321(3): 517-523, https://www.webofscience.com/wos/woscc/full-record/WOS:000223277600002.[46] Stephen P Goff, Guangxia Gao. Isolation of suppressor genes that restore retrovirus susceptibility to a virus-resistant cell line. RETROVIROLOGY[J]. 2004, 1(1): http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201707076241247ZK.[47] Guo, XM, Carroll, JWN, MacDonald, MR, Goff, SP, Gao, GX. The zinc finger antiviral protein directly binds to specific viral mRNAs through the CCCH zinc finger motifs. JOURNAL OF VIROLOGY[J]. 2004, 78(23): 12781-12787, http://124.16.144.217/handle/311023/1382.[48] 高光侠. Inhibition of Retroviral RNA Production by ZAP, a CCCH-type Antiviral Protein. SCIENCE. 2002,