基本信息
韩建  男  硕导  中国科学院水生生物研究所
电子邮件: hanjian@ihb.ac.cn
通信地址: 湖北省武汉市武昌区东湖南路7号
邮政编码:

研究领域

环境毒理学

生态毒理学

水环境污染与健康

水生态安全评价

动物毒理学研究模型

招生信息

欢迎感兴趣的同学报考【硕士研究生】!

招生专业
071004-水生生物学
招生方向
环境毒理学,生态毒理学
水环境污染,水生态安全评价
动物毒理学模型

教育背景

2011-09--2014-07   中国科学院大学   博士

工作经历

   
工作简历
2019-12~现在, 中国科学院水生生物研究所, 副研究员
2018-12~2019-12,中国科学院水生生物研究所, 助理研究员
2015-02~2018-12,山东省科学院生物研究所, 助理研究员
社会兼职
2023-01-31-今,环境领域著名期刊Aquatic Toxicology编委, 编委

出版信息

   
发表论文
(1) Transcriptome reveals overview of Ca 2+dose-dependent metabolism disorders in zebrafish larvae after Cd 2+exposure, JOURNAL OF ENVIRONMENTAL SCIENCES, 2023, 通讯作者
(2) Antibiotic resistance genes and their links with bacteria and environmental factors in three predominant freshwater aquaculture modes, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2022, 通讯作者
(3) Endocrine disrupting effects induced by levonorgestrel linked to altered DNA methylation in rare minnow (Gobiocypris rarus), Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2022, 通讯作者
(4) Decabromodiphenyl ethane induced hyperactivity in developing zebrafish at environmentally relevant concentrations, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2022, 第 8 作者
(5) 南水北调中线总干渠水中酞酸酯类物质含量及风险评价, Levels and Risk Assessment of PAEs in Surface Water in Main Canal of Middle Route of South-to-North Water Diversion Project, 生态毒理学报, 2022, 第 5 作者
(6) Human viruses lurking in the environment activated by excessive use of COVID-19 prevention supplies, Environment International, 2022, 第 3 作者
(7) Neurotoxicity of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion, SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 通讯作者
(8) Effects of nano-TiO2 on the bioavailability and toxicity of bis (2-ethylhexyl)-2,3,4,5-tetrabromophthalate (TBPH) in developing zebrafish, Chemosphere, 2022, 通讯作者
(9) New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish, SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 通讯作者
(10) New evidence for neurobehavioral toxicity of deltamethrin at environmentally relevant levels in zebrafish, SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 通讯作者
(11) In vitro biolayer interferometry analysis of acetylcholinesterase as a potential target of aryl-organophosphorus flame-retardants, JOURNAL OF HAZARDOUS MATERIALS, 2021, 第 4 作者
(12) Nonalcoholic Fatty Liver Disease Development in Zebrafish upon Exposure to Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate, a Novel Brominated Flame Retardant, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2021, 第 6 作者
(13) Bioconcentration and developmental neurotoxicity of novel brominated flame retardants, hexabromobenzene and pentabromobenzene in zebrafish, ENVIRONMENTAL POLLUTION, 2021, 第 6 作者
(14) Bis(2-ethylhexyl)-tetrabromophthalate induces zebrafish obesity by altering the brain-gut axis and intestinal microbial composition, ENVIRONMENTAL POLLUTION, 2021, 通讯作者
(15) Effects of SiO2 nanoparticles on the uptake of tetrabromobisphenol A and its impact on the thyroid endocrine system in zebrafish larvae, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 第 2 作者
(16) Early-life exposure to tris (1,3-dichloro-2-propyl) phosphate caused multigenerational neurodevelopmental toxicity in zebrafish via altering maternal thyroid hormones transfer and epigenetic modifications, ENVIRONMENTAL POLLUTION, 2021, 第 3 作者
(17) 长江中游岸线水域典型污染物种类与来源解析, Typical Pollutants in Waters along the Riverbank of the Yangtze River Middle Mainstream:Species Identification and Source Analysis, 长江科学院院报, 2021, 第 7 作者
(18) Early-life exposure to the organophosphorus flame-retardant tris (1,3-dichloro-2-propyl) phosphate induces delayed neurotoxicity associated with DNA methylation in adult zebrafish, ENVIRONMENT INTERNATIONAL, 2020, 第 6 作者
(19) Bioconcentration of 2,4,6-tribromophenol (TBP) and thyroid endocrine disruption in zebrafish larvae, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 通讯作者
(20) Titanium dioxide nanoparticles enhanced thyroid endocrine disruption of pentachlorophenol rather than neurobehavioral defects in zebrafish larvae, CHEMOSPHERE, 2020, 通讯作者
(21) Nano-TiO2 enhanced bioaccumulation and developmental neurotoxicity of bisphenol a in zebrafish larvae, ENVIRONMENTAL RESEARCH, 2020, 通讯作者
(22) Optical toxicity of triphenyl phosphate in zebrafish larvae, AQUATIC TOXICOLOGY, 2019, 通讯作者
(23) Exposure to cadmium causes inhibition of otolith development and behavioral impairment in zebrafish larvae, AQUATIC TOXICOLOGY, 2019, 通讯作者
(24) 孕激素左炔诺孕酮长期低剂量暴露对雄性斑马鱼的生殖毒性, Reproductive Toxicity in Male Zebrafish after Long-term Exposure to Low Concentrations of Progestin Levonorgestrel, 生态毒理学报, 2019, 第 2 作者
(25) Impact of co-exposure to titanium dioxide nanoparticles and Pb on zebrafish embryos, CHEMOSPHERE, 2019, 通讯作者
(26) Bioconcentration, depuration and toxicity of Pb in the presence of titanium dioxide nanoparticles in zebrafish larvae, AQUATIC TOXICOLOGY, 2019, 通讯作者
(27) 苯并芘和邻苯二甲酸二(2-乙基己基)酯复合暴露对稀有鮈鲫的内分泌干扰效应研究, Endocrine Disruption Effects of Benzo(a) pyrene and Di-2-ethylhexyl Phthalate on Chinese Rare Minnow(Gobiocypris rarus), 生态毒理学报, 2019, 第 3 作者
(28) Bioconcentration, Biotransformation, and Thyroid Endocrine Disruption of Decabromodiphenyl Ethane (Dbdpe), A Novel Brominated Flame Retardant, in Zebrafish Larvae, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 第 6 作者
(29) Endocrine disruption in Chinese rare minnow (Gobiocypris rarus) after long-term exposure to low environmental concentrations of progestin megestrol acetate, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 第 2 作者
(30) 孕激素醋酸甲地孕酮和雌激素乙炔雌二醇复合暴露对斑马鱼的生殖毒性, 环境化学, 2017, 第 1 作者
(31) Structure-Based Investigation on the Binding and Activation of Typical Pesticides With Thyroid Receptor, TOXICOLOGICAL SCIENCES, 2017, 第 2 作者
(32) The binary mixtures of megestrol acetate and 17α-ethynylestradiol adversely affect zebrafish reproduction, ENVIRONMENTAL POLLUTION, 2016, 第 2 作者
(33) THE DEVELOPMENTAL NEUROTOXICITY OF POLYBROMINATED DIPHENYL ETHERS: EFFECT OF DE-71 ON DOPAMINE IN ZEBRAFISH LARVAE, ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2015, 第 6 作者
(34) the synthetic progestin megestrol acetate adversely affects zebrafish reproduction, AQUATICTOXICOLOGY, 2014, 第 1 作者
(35) Endocrine disruption by di-(2-ethylhexyl)-phthalate in Chinese rare minnow (Gobiocypris rarus), ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 2013, 第 5 作者
(36) Toxicogenomic Responses of Zebrafish Embryos/Larvae to Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) Reveal Possible Molecular Mechanisms of Developmental Toxicity, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2013, 第 2 作者
(37) Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2,4-dichlorophenol, AQUATIC TOXICOLOGY, 2012, 第 2 作者
发表著作
(1) 环境化学前沿(第三辑), Frontiers of Environmental Chemistry, 科学出版社, 2022-07, 第 其他 作者

科研活动

   
科研项目
( 1 ) 基于斑马鱼模型研究重金属镉对耳石发育的毒性效应及机制, 负责人, 国家任务, 2019-01--2021-12
( 2 ) 智能感知修复生物体系的环境风险评价, 负责人, 国家任务, 2020-11--2025-10
( 3 ) 典型溴代阻燃剂与纳米二氧化钛、有机碳相互作用诱导的斑马鱼甲状腺内分泌干扰效应, 参与, 国家任务, 2020-01--2023-12
( 4 ) 十溴二苯乙烷对斑马鱼脂质代谢的干扰效应与机制, 负责人, 国家任务, 2023-01--2026-12